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Volumn 22, Issue 2, 2012, Pages 109-116

Thymosin β4: A potential molecular target for tumor therapy

Author keywords

Actin sequestering; Cancer therapy; Cell migration; Inflammation; Thymosin 4

Indexed keywords

ANGIOGENIC FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MATRILYSIN; REACTIVE OXYGEN METABOLITE; THYMOSIN BETA4; VASCULOTROPIN;

EID: 84865636011     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevEukarGeneExpr.v22.i2.30     Document Type: Article
Times cited : (17)

References (55)
  • 1
    • 0033949064 scopus 로고    scopus 로고
    • Sequestered actin in chick embryo fibroblasts
    • Nagamalleswari K, Safer D. Sequestered actin in chick embryo fibroblasts. Mol Cell Biochem. 2000;209(1-2):63-7.
    • (2000) Mol Cell Biochem , vol.209 , Issue.1-2 , pp. 63-67
    • Nagamalleswari, K.1    Safer, D.2
  • 2
    • 51449109987 scopus 로고    scopus 로고
    • Thymosin beta4 is cytoprotective in human gingival fibroblasts
    • Reti R, Kwon E, Qiu P, Wheater M, Sosne G. Thymosin beta4 is cytoprotective in human gingival fibroblasts. Eur J Oral Sci. 2008;116(5):424-30.
    • (2008) Eur J Oral Sci , vol.116 , Issue.5 , pp. 424-430
    • Reti, R.1    Kwon, E.2    Qiu, P.3    Wheater, M.4    Sosne, G.5
  • 5
    • 33645525974 scopus 로고    scopus 로고
    • Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells
    • Mu H, Ohashi R, Yang H, Wang X, Li M, Lin P, Yao Q, Chen C. Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells. Cell Motil Cytoskeleton. 2006;63(4):222-30.
    • (2006) Cell Motil Cytoskeleton , vol.63 , Issue.4 , pp. 222-230
    • Mu, H.1    Ohashi, R.2    Yang, H.3    Wang, X.4    Li, M.5    Lin, P.6    Yao, Q.7    Chen, C.8
  • 6
    • 0035947763 scopus 로고    scopus 로고
    • Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning
    • Roy P, Rajfur Z, Jones D, Marriott G, Loew L, Jacobson K. Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning. J Cell Biol. 2001;153(5):1035-48.
    • (2001) J Cell Biol , vol.153 , Issue.5 , pp. 1035-1048
    • Roy, P.1    Rajfur, Z.2    Jones, D.3    Marriott, G.4    Loew, L.5    Jacobson, K.6
  • 7
    • 0642303652 scopus 로고    scopus 로고
    • The actin binding site on thymosin beta4 promotes angiogenesis
    • Philp D, Huff T, Gho YS, Hannappel E, Kleinman HK. The actin binding site on thymosin beta4 promotes angiogenesis. FASEB J. 2003;17(14):2103-5.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 2103-2105
    • Philp, D.1    Huff, T.2    Gho, Y.S.3    Hannappel, E.4    Kleinman, H.K.5
  • 8
    • 35348975977 scopus 로고    scopus 로고
    • Pressure ulcers: A role for thymosin beta4
    • Francis Godschalk M. Pressure ulcers: a role for thymosin beta4. Ann N Y Acad Sci.2007;1112:413-7.
    • (2007) Ann N Y Acad Sci , vol.1112 , pp. 413-417
    • Francis, G.M.1
  • 9
    • 35748956386 scopus 로고    scopus 로고
    • Thymosin beta4 and angiogenesis: Modes of action and therapeutic potential
    • Smart N, Rossdeutsch A, Riley PR. Thymosin beta4 and angiogenesis: modes of action and therapeutic potential. Angiogenesis. 2007;10(4):229-41.
    • (2007) Angiogenesis , vol.10 , Issue.4 , pp. 229-241
    • Smart, N.1    Rossdeutsch, A.2    Riley, P.R.3
  • 12
    • 0342576715 scopus 로고
    • Complete amino acid sequence of bovine thymosin beta 4: A thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations
    • Low TL HS, Goldstein AL. Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Proc Natl Acad Sci U S A. 1981;78(2):1162-6.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , Issue.2 , pp. 1162-1166
    • Low, T.L.H.S.1    Goldstein, A.L.2
  • 13
    • 20944441453 scopus 로고    scopus 로고
    • Molecular cloning and structural characterization of the functional human thymosin beta4 gene
    • Yang SP, Lee HJ, Su Y. Molecular cloning and structural characterization of the functional human thymosin beta4 gene. Mol Cell Biochem. 2005;272(1-2):97-105.
    • (2005) Mol Cell Biochem , vol.272 , Issue.1-2 , pp. 97-105
    • Yang, S.P.1    Lee, H.J.2    Su, Y.3
  • 14
    • 2542492280 scopus 로고    scopus 로고
    • Coupling of folding and binding of thymosin beta4 upon interaction with monomeric actin monitored by nuclear magnetic resonance
    • Domanski M HM, Coutant J, Gutsche-Perelroizen I, Bontems F, Carlier MF, Guittet E, van Heijenoort C. Coupling of folding and binding of thymosin beta4 upon interaction with monomeric actin monitored by nuclear magnetic resonance. J Biol Chem. 2004;279(22):23637-45.
    • (2004) J Biol Chem , vol.279 , Issue.22 , pp. 23637-23645
    • Domanski, M.H.M.1    Coutant, J.2    Gutsche-Perelroizen, I.3    Bontems, F.4    Carlier, M.F.5    Guittet, E.6    van Heijenoort, C.7
  • 17
    • 35348933141 scopus 로고    scopus 로고
    • Subcellular distribution of thymosin beta4
    • Zoubek RE, Hannappel E. Subcellular distribution of thymosin beta4. Ann N Y Acad Sci. 2007;1112:442-50.
    • (2007) Ann N Y Acad Sci , vol.1112 , pp. 442-450
    • Zoubek, R.E.1    Hannappel, E.2
  • 19
    • 77956455480 scopus 로고    scopus 로고
    • Thymosin beta4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1alpha-dependent manner
    • Jo JO, Kim SR, Bae MK, Kang YJ, Ock MS, Kleinman HK, Cha HJ. Thymosin beta4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1alpha-dependent manner. Biochim Biophys Acta. 2010;1803(11):1244-51.
    • (2010) Biochim Biophys Acta , vol.1803 , Issue.11 , pp. 1244-1251
    • Jo, J.O.1    Kim, S.R.2    Bae, M.K.3    Kang, Y.J.4    Ock, M.S.5    Kleinman, H.K.6    Cha, H.J.7
  • 21
    • 0037607199 scopus 로고    scopus 로고
    • Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells
    • Wang WS CP, Hsiao HL, Ju SY, Su Y. Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells. Oncogene. 2003;22(21):3297-306.
    • (2003) Oncogene , vol.22 , Issue.21 , pp. 3297-3306
    • Wang, W.S.C.P.1    Hsiao, H.L.2    Ju, S.Y.3    Su, Y.4
  • 22
    • 4444295381 scopus 로고    scopus 로고
    • Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma
    • Wang WS CP, Hsiao HL, Wang HS, Liang WY, Su Y. Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma. Oncogene. 2004;23(39):6666-71.
    • (2004) Oncogene , vol.23 , Issue.39 , pp. 6666-6671
    • Wang, W.S.C.P.1    Hsiao, H.L.2    Wang, H.S.3    Liang, W.Y.4    Su, Y.5
  • 23
    • 84857654849 scopus 로고    scopus 로고
    • Evaluation of thymosin beta4 in the regulation of epithelial-mesenchymal transformation in urothelial carcinoma
    • Wang ZY, Zeng FQ, Zhu ZH, Jiang GS, Lv L, Wan F, Dong R, Xiao XY, Xing SA. Evaluation of thymosin beta4 in the regulation of epithelial-mesenchymal transformation in urothelial carcinoma. Urol Oncol. 2012;30(2):167-76.
    • (2012) Urol Oncol , vol.30 , Issue.2 , pp. 167-176
    • Wang, Z.Y.1    Zeng, F.Q.2    Zhu, Z.H.3    Jiang, G.S.4    Lv, L.5    Wan, F.6    Dong, R.7    Xiao, X.Y.8    Xing, S.A.9
  • 24
    • 34247479062 scopus 로고    scopus 로고
    • Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase
    • Huang HC, Hu CH, Tang MC, Wang WS, Chen PM, Su Y. Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. Oncogene. 2007;26(19):2781-90.
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2781-2790
    • Huang, H.C.1    Hu, C.H.2    Tang, M.C.3    Wang, W.S.4    Chen, P.M.5    Su, Y.6
  • 25
    • 33645088351 scopus 로고    scopus 로고
    • Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively
    • Hsiao HL WW, Chen PM, Su Y. Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively. Carcinogenesis. 2006;27(5):936-44.
    • (2006) Carcinogenesis , vol.27 , Issue.5 , pp. 936-944
    • Hsiao, H.L.W.W.1    Chen, P.M.2    Su, Y.3
  • 26
    • 77955768685 scopus 로고    scopus 로고
    • Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells
    • Oh JM ME. Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells. Life Sci. 2010;87(9-10):286-93.
    • (2010) Life Sci , vol.87 , Issue.9-10 , pp. 286-293
    • Oh, J.M.M.E.1
  • 27
    • 0344858002 scopus 로고    scopus 로고
    • Role of thymosin beta4 in tumor metastasis and angiogenesis
    • Cha HJ, Jeong MJ, Kleinman HK. Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst. 2003;95(22):1674-80.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.22 , pp. 1674-1680
    • Cha, H.J.1    Jeong, M.J.2    Kleinman, H.K.3
  • 28
    • 67650076573 scopus 로고    scopus 로고
    • Identification of integrins alpha6 and beta7 as c-Jun-and transformation-relevant genes in highly invasive fibrosarcoma cells
    • Kielosto M, Nummela P, Jarvinen K, Yin M, Holtta E. Identification of integrins alpha6 and beta7 as c-Jun-and transformation-relevant genes in highly invasive fibrosarcoma cells. Int J Cancer. 2009.125(5):1065-73.
    • (2009) Int J Cancer , vol.125 , Issue.5 , pp. 1065-1073
    • Kielosto, M.1    Nummela, P.2    Jarvinen, K.3    Yin, M.4    Holtta, E.5
  • 29
    • 70350370754 scopus 로고    scopus 로고
    • Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells
    • Kim A, Son M, Kim KI, Yang Y, Song EY, Lee HG, Lim JS. Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells. Exp Cell Res. 2009;315(19):3325-35.
    • (2009) Exp Cell Res , vol.315 , Issue.19 , pp. 3325-3335
    • Kim, A.1    Son, M.2    Kim, K.I.3    Yang, Y.4    Song, E.Y.5    Lee, H.G.6    Lim, J.S.7
  • 30
    • 80052709604 scopus 로고    scopus 로고
    • Elevated expression of thymosin beta4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1alpha in early-stage cervical cancers
    • Kim NS, Kang YJ, Jo JO, Kim HY, Oh YR, Kim YO, Jung MH, Ock MS, Cha HJ. Elevated expression of thymosin beta4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1alpha in early-stage cervical cancers. Pathol Oncol Res. 2011;17(3):493-502.
    • (2011) Pathol Oncol Res , vol.17 , Issue.3 , pp. 493-502
    • Kim, N.S.1    Kang, Y.J.2    Jo, J.O.3    Kim, H.Y.4    Oh, Y.R.5    Kim, Y.O.6    Jung, M.H.7    Ock, M.S.8    Cha, H.J.9
  • 34
    • 58049195459 scopus 로고    scopus 로고
    • Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population
    • Steiniger SC, Coppinger JA, Kruger JA, Yates J, 3rd, Janda KD. Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population. Stem Cells. 2008;26(12):3037-46.
    • (2008) Stem Cells , vol.26 , Issue.12 , pp. 3037-3046
    • Steiniger, S.C.1    Coppinger, J.A.2    Kruger, J.A.3    Yates III, J.4    Janda, K.D.5
  • 35
    • 0842346016 scopus 로고    scopus 로고
    • Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development
    • Philp D, Goldstein AL, Kleinman HK. Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development. Mech Ageing Dev. 2004;125(2):113-15.
    • (2004) Mech Ageing Dev , vol.125 , Issue.2 , pp. 113-115
    • Philp, D.1    Goldstein, A.L.2    Kleinman, H.K.3
  • 37
    • 33746919929 scopus 로고    scopus 로고
    • Thymosin beta4 inhibits benzalkonium chloride-mediated apoptosis in corneal and conjunctival epithelial cells in vitro
    • Sosne G, Albeiruti AR, Hollis B, Siddiqi A, Ellenberg D, Kurpakus-Wheater M. Thymosin beta4 inhibits benzalkonium chloride-mediated apoptosis in corneal and conjunctival epithelial cells in vitro. Exp Eye Res. 2006;83(3):502-7.
    • (2006) Exp Eye Res , vol.83 , Issue.3 , pp. 502-507
    • Sosne, G.1    Albeiruti, A.R.2    Hollis, B.3    Siddiqi, A.4    Ellenberg, D.5    Kurpakus-Wheater, M.6
  • 38
    • 23244447079 scopus 로고    scopus 로고
    • Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury
    • Sosne G, Christopherson PL, Barrett RP, Fridman R. Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury. Invest Ophthalmol Vis Sc.i 2005;46(7):2388-95.
    • (2005) Invest Ophthalmol Vis Sc.i , vol.46 , Issue.7 , pp. 2388-2395
    • Sosne, G.1    Christopherson, P.L.2    Barrett, R.P.3    Fridman, R.4
  • 39
    • 0036025330 scopus 로고    scopus 로고
    • Thymosin beta4 promotes human conjunctival epithelial cell migration
    • Sosne G, Hafeez S, Greenberry AL, 2nd, Kurpakus-Wheater M. Thymosin beta4 promotes human conjunctival epithelial cell migration. Curr Eye Res. 2002;24(4):268-73.
    • (2002) Curr Eye Res , vol.24 , Issue.4 , pp. 268-273
    • Sosne, G.1    Hafeez, S.2    Greenberry II, A.L.3    Kurpakus-Wheater, M.4
  • 40
    • 77954447831 scopus 로고    scopus 로고
    • Biological activities of thymosin beta4 defined by active sites in short peptide sequences
    • Sosne G, Qiu P, Goldstein AL, Wheater M. Biological activities of thymosin beta4 defined by active sites in short peptide sequences. FASEB J. 2010;24(7):2144-51.
    • (2010) FASEB J , vol.24 , Issue.7 , pp. 2144-2151
    • Sosne, G.1    Qiu, P.2    Goldstein, A.L.3    Wheater, M.4
  • 41
    • 77951845671 scopus 로고    scopus 로고
    • Thymosin beta4 and corneal wound healing: Visions of the future
    • Sosne G, Qiu P, Kurpakus-Wheater M, Matthew H. Thymosin beta4 and corneal wound healing: visions of the future. Ann N Y Acad Sci. 2010;1194:190-98.
    • (2010) Ann N Y Acad Sci , vol.1194 , pp. 190-198
    • Sosne, G.1    Qiu, P.2    Kurpakus-Wheater, M.3    Matthew, H.4
  • 42
    • 2142763869 scopus 로고    scopus 로고
    • Thymosin-beta4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro
    • Sosne G, Siddiqi A, Kurpakus-Wheater M. Thymosin-beta4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro. Invest Ophthalmol Vis Sci. 2004;45(4):1095-100.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.4 , pp. 1095-1100
    • Sosne, G.1    Siddiqi, A.2    Kurpakus-Wheater, M.3
  • 43
    • 38149091473 scopus 로고    scopus 로고
    • Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells
    • Leeanansaksiri W, DeSimone SK, Huff T, Hannappel E, Huff TF. Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells. Chem Biodivers. 2004;1(7):1091-100.
    • (2004) Chem Biodivers , vol.1 , Issue.7 , pp. 1091-1100
    • Leeanansaksiri, W.1    Desimone, S.K.2    Huff, T.3    Hannappel, E.4    Huff, T.F.5
  • 44
    • 9644281738 scopus 로고    scopus 로고
    • Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
    • Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-72.
    • (2004) Nature , vol.432 , Issue.7016 , pp. 466-472
    • Bock-Marquette, I.1    Saxena, A.2    White, M.D.3    Dimaio, J.M.4    Srivastava, D.5
  • 45
    • 67649206633 scopus 로고    scopus 로고
    • Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway
    • Qiu FY, Song XX, Zheng H, Zhao YB, Fu GS. Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway. J Cardiovasc Pharmacol. 2009;53(3):209-14.
    • (2009) J Cardiovasc Pharmacol , vol.53 , Issue.3 , pp. 209-214
    • Qiu, F.Y.1    Song, X.X.2    Zheng, H.3    Zhao, Y.B.4    Fu, G.S.5
  • 46
    • 79959232291 scopus 로고    scopus 로고
    • Thymosin-beta4 (Tbeta4) blunts PDGF-dependent phosphorylation and binding of AKT to actin in hepatic stellate cells
    • Reyes-Gordillo K, Shah R, Popratiloff A, Fu S, Hindle A, Brody F, Rojkind M. Thymosin-beta4 (Tbeta4) blunts PDGF-dependent phosphorylation and binding of AKT to actin in hepatic stellate cells. Am J Pathol. 2011;178(5):2100-8.
    • (2011) Am J Pathol , vol.178 , Issue.5 , pp. 2100-2108
    • Reyes-Gordillo, K.1    Shah, R.2    Popratiloff, A.3    Fu, S.4    Hindle, A.5    Brody, F.6    Rojkind, M.7
  • 51
    • 76749109357 scopus 로고    scopus 로고
    • Thymosin-beta4 attenuates ethanol-induced neurotoxicity in cultured cerebral cortical astrocytes by inhibiting apoptosis
    • Yang H, Cui GB, Jiao XY, Wang J, Ju G, You SW. Thymosin-beta4 attenuates ethanol-induced neurotoxicity in cultured cerebral cortical astrocytes by inhibiting apoptosis. Cell Mol Neurobiol. 2010;30(1):149-60.
    • (2010) Cell Mol Neurobiol , vol.30 , Issue.1 , pp. 149-160
    • Yang, H.1    Cui, G.B.2    Jiao, X.Y.3    Wang, J.4    Ju, G.5    You, S.W.6
  • 52
    • 84856423405 scopus 로고    scopus 로고
    • Thymosin beta4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation
    • Zhao Y, Qiu F, Xu S, Yu L, Fu G. Thymosin beta4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation. J Cell Physiol.
    • J Cell Physiol
    • Zhao, Y.1    Qiu, F.2    Xu, S.3    Yu, L.4    Fu, G.5
  • 53
    • 0031054485 scopus 로고    scopus 로고
    • Functional roles of Phe of deacetyl-thymosin beta4 in the impaired blastogenic response of uraemic T-lymphocytes
    • Abiko T, Sekino H. Functional roles of Phe of deacetyl-thymosin beta4 in the impaired blastogenic response of uraemic T-lymphocytes. Mediators Inflamm. 1997;6(1):64-68.
    • (1997) Mediators Inflamm , vol.6 , Issue.1 , pp. 64-68
    • Abiko, T.1    Sekino, H.2
  • 54
    • 80054678987 scopus 로고    scopus 로고
    • Increased levels of thymosin beta4 in synovial fluid of patients with rheumatoid arthritis: Association of thymosin beta4 with other factors that are involved in inflammation and bone erosion in joints
    • Choi HM, Lee YA, Yang HI, Yoo MC, Kim KS. Increased levels of thymosin beta4 in synovial fluid of patients with rheumatoid arthritis: association of thymosin beta4 with other factors that are involved in inflammation and bone erosion in joints. Int J Rheum Dis. 2011;14(4):320-24.
    • (2011) Int J Rheum Dis , vol.14 , Issue.4 , pp. 320-324
    • Choi, H.M.1    Lee, Y.A.2    Yang, H.I.3    Yoo, M.C.4    Kim, K.S.5
  • 55
    • 79957922304 scopus 로고    scopus 로고
    • Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK
    • Qiu P, Wheater MK, Qiu Y, Sosne G. Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK. FASEB J. 2011;25(6):1815-26.
    • (2011) FASEB J , vol.25 , Issue.6 , pp. 1815-1826
    • Qiu, P.1    Wheater, M.K.2    Qiu, Y.3    Sosne, G.4


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