Thymosin β4 targeting impairs tumorigenic activity of colon cancer stem cells

FASEB Journal

Volumn 24, Issue 11, 2010, Pages 4291-4301

  Ricci Vitiani, Lucia ^a   Mollinari, Cristiana ^a,b   Di Martino, Simona ^a   Biffoni, Mauro ^a   Pilozzi, Emanuela ^c   Pagliuca, Alfredo ^a   De Stefano, Maria Chiara ^a   Circo, Rita ^d   Merlo, Daniela ^a,e   De Maria, Ruggero ^a,d   Garaci, Enrico ^f  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b CNR   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Mediterranean Institute of Oncology   (Italy)

^e IRCCS SAN RAFFAELE PISANA   (Italy)

^f UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Actin cytoskeleton; Cell cycle; Target therapy; Tumor growth

Indexed keywords

INTEGRIN LINKED KINASE; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; THYMOSIN BETA4; INTEGRIN-LINKED KINASE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; THYMOSIN; THYMOSIN BETA(4);

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER STEM CELL; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; CELL DIFFERENTIATION; CELL MOTION; COLON TUMOR; CYTOLOGY; DOWN REGULATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE; VIROLOGY;

MUS;

ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLONIC NEOPLASMS; DOWN-REGULATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LENTIVIRUS; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; ONCOGENE PROTEIN V-AKT; PROTEIN-SERINE-THREONINE KINASES; PTEN PHOSPHOHYDROLASE; THYMOSIN;

EID: 78649844351     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-159970     Document Type: Article

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