메뉴 건너뛰기




Volumn 64, Issue 1, 2012, Pages 5-15

Umbilical Cord Blood-Derived Stromal Cells Regulate Megakaryocytic Proliferation and Migration Through SDF-1/PECAM-1 Pathway

Author keywords

Cell migration; Cell proliferation; Cell signaling; Human umbilical cord blood derived stromal cells; Megakaryocytes; Platelet endothelial cell adhesion molecule 1; Stromal cell derived factor 1

Indexed keywords

CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CXCL12 PROTEIN, HUMAN; STROMAL CELL DERIVED FACTOR 1;

EID: 84865555338     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-012-9362-1     Document Type: Article
Times cited : (3)

References (50)
  • 1
    • 0037082510 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism
    • Lataillade, J. J., Clay, D., Bourin, P., Herodin, F., Dupuy, C., Jasmin, C., et al. (2002). Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. Blood, 99, 1117-1129.
    • (2002) Blood , vol.99 , pp. 1117-1129
    • Lataillade, J.J.1    Clay, D.2    Bourin, P.3    Herodin, F.4    Dupuy, C.5    Jasmin, C.6
  • 2
    • 6344293549 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1)\CXCR4 couple plays multiple roles on haematopoietic progenitors at the border between the old cytokine and new chemokine worlds: survival, cell cycling and trafficking
    • Lataillade, J. J., Domenech, J., & Le Bousse-Kerdiles, M. C. (2004). Stromal cell-derived factor-1 (SDF-1)\CXCR4 couple plays multiple roles on haematopoietic progenitors at the border between the old cytokine and new chemokine worlds: survival, cell cycling and trafficking. European Cytokine Network, 15, 177-188.
    • (2004) European Cytokine Network , vol.15 , pp. 177-188
    • Lataillade, J.J.1    Domenech, J.2    Le Bousse-Kerdiles, M.C.3
  • 3
    • 0030878970 scopus 로고    scopus 로고
    • Regulation of megakaryocytopoiesis by thrombopoietin and stromal cells
    • Nagata, Y., Nagahisa, H., Nagasawa, T., & Todokoro, K. (1997). Regulation of megakaryocytopoiesis by thrombopoietin and stromal cells. Leukemia, 11(Suppl 3), 435-438.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 3 , pp. 435-438
    • Nagata, Y.1    Nagahisa, H.2    Nagasawa, T.3    Todokoro, K.4
  • 4
    • 4544277651 scopus 로고    scopus 로고
    • Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
    • Tong, W., & Lodish, H. F. (2004). Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. Journal of Experimental Medicine, 200, 569-580.
    • (2004) Journal of Experimental Medicine , vol.200 , pp. 569-580
    • Tong, W.1    Lodish, H.F.2
  • 6
    • 11144356721 scopus 로고    scopus 로고
    • Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
    • Avecilla, S. T., Hattori, K., Heissig, B., Tejada, R., Liao, F., Shido, K., et al. (2004). Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nature Medicine, 10, 64-71.
    • (2004) Nature Medicine , vol.10 , pp. 64-71
    • Avecilla, S.T.1    Hattori, K.2    Heissig, B.3    Tejada, R.4    Liao, F.5    Shido, K.6
  • 7
    • 1642433313 scopus 로고    scopus 로고
    • SDF-1 and CXCR4 in normal and malignant hematopoiesis
    • Juarez, J., & Bendall, L. (2004). SDF-1 and CXCR4 in normal and malignant hematopoiesis. Histology and Histopathology, 19, 299-309.
    • (2004) Histology and Histopathology , vol.19 , pp. 299-309
    • Juarez, J.1    Bendall, L.2
  • 8
    • 0034142019 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)
    • Hodohara, K., Fujii, N., Yamamoto, N., & Kaushansky, K. (2000). Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK). Blood, 95, 769-775.
    • (2000) Blood , vol.95 , pp. 769-775
    • Hodohara, K.1    Fujii, N.2    Yamamoto, N.3    Kaushansky, K.4
  • 9
    • 0038120892 scopus 로고    scopus 로고
    • Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology
    • Newman, P. J., & Newman, D. K. (2003). Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. Arteriosclerosis, Thrombosis, and Vascular Biology, 23, 953-964.
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , pp. 953-964
    • Newman, P.J.1    Newman, D.K.2
  • 10
    • 34248341412 scopus 로고    scopus 로고
    • A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice
    • Dhanjal, T. S., Pendaries, C., Ross, E. A., Larson, M. K., Protty, M. B., Buckley, C. D., et al. (2007). A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice. Blood, 109, 4237-4244.
    • (2007) Blood , vol.109 , pp. 4237-4244
    • Dhanjal, T.S.1    Pendaries, C.2    Ross, E.A.3    Larson, M.K.4    Protty, M.B.5    Buckley, C.D.6
  • 12
    • 78751538825 scopus 로고    scopus 로고
    • Cotransplantation of human umbilical cord blood-derived stromal cells enhances hematopoietic reconstitution and engraftment in irradiated BABL/c mice
    • Liu, Y., Yi, L., Zhang, X., Gao, L., Zhang, C., Feng, Y. M., et al. (2011). Cotransplantation of human umbilical cord blood-derived stromal cells enhances hematopoietic reconstitution and engraftment in irradiated BABL/c mice. Cancer Biology and Therapy, 11, 84-94.
    • (2011) Cancer Biology and Therapy , vol.11 , pp. 84-94
    • Liu, Y.1    Yi, L.2    Zhang, X.3    Gao, L.4    Zhang, C.5    Feng, Y.M.6
  • 13
    • 77953585878 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived stromal cells: multifaceted regulators of megakaryocytopoiesis
    • Gao, L., Chen, X. H., Feng, Y. M., Zhang, X., Yu, S. C., Zhang, C., et al. (2010). Human umbilical cord blood-derived stromal cells: multifaceted regulators of megakaryocytopoiesis. Cell Cycle, 9, 1342-1353.
    • (2010) Cell Cycle , vol.9 , pp. 1342-1353
    • Gao, L.1    Chen, X.H.2    Feng, Y.M.3    Zhang, X.4    Yu, S.C.5    Zhang, C.6
  • 14
    • 57849099594 scopus 로고    scopus 로고
    • Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol
    • Catani, M., Fezza, F., Baldassarri, S., Gasperi, V., Bertoni, A., Pasquariello, N., et al. (2009). Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. Journal of Molecular Medicine, 87, 65-74.
    • (2009) Journal of Molecular Medicine , vol.87 , pp. 65-74
    • Catani, M.1    Fezza, F.2    Baldassarri, S.3    Gasperi, V.4    Bertoni, A.5    Pasquariello, N.6
  • 15
    • 0021382037 scopus 로고
    • Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL)
    • Tabilio, A., Rosa, J., Testa, U., Kieffer, N., Nurden, A., Del Canizo, M., et al. (1984). Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL). EMBO Journal, 3, 453-459.
    • (1984) EMBO Journal , vol.3 , pp. 453-459
    • Tabilio, A.1    Rosa, J.2    Testa, U.3    Kieffer, N.4    Nurden, A.5    Del Canizo, M.6
  • 19
    • 0026808723 scopus 로고
    • Interaction of fibroblast growth factor (FGF) with megakaryocytopoiesis and demonstration of FGF receptor expression in megakaryocytes and megakaryocytic-like cells
    • Bikfalvi, A., Han, Z. C., & Fuhrmann, G. (1992). Interaction of fibroblast growth factor (FGF) with megakaryocytopoiesis and demonstration of FGF receptor expression in megakaryocytes and megakaryocytic-like cells. Blood, 80, 1905-1913.
    • (1992) Blood , vol.80 , pp. 1905-1913
    • Bikfalvi, A.1    Han, Z.C.2    Fuhrmann, G.3
  • 20
    • 50849127848 scopus 로고    scopus 로고
    • Effects of RNA interference inhibiting SDF-1 expression in bone marrow stromal cells on the proliferation and apoptosis of co-cultured Jurkat cells
    • (in Chinese)
    • Yang, W. B., Kong, P. Y., Chang, C., Wei, L., Zeng, D. F., Peng, X. G., et al. (2005) Effects of RNA interference inhibiting SDF-1 expression in bone marrow stromal cells on the proliferation and apoptosis of co-cultured Jurkat cells. Zhonghua Xue Ye Xue Za Zhi, 26, 421-424 (in Chinese).
    • (2005) Zhonghua Xue Ye Xue Za Zhi , vol.26 , pp. 421-424
    • Yang, W.B.1    Kong, P.Y.2    Chang, C.3    Wei, L.4    Zeng, D.F.5    Peng, X.G.6
  • 21
    • 33846947172 scopus 로고    scopus 로고
    • The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy
    • Bergom, C., Goel, R., Paddock, C., Gao, C., Newman, D. K., Matsuyama, S., et al. (2006). The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. Cancer Biology and Therapy, 5, 1699-1707.
    • (2006) Cancer Biology and Therapy , vol.5 , pp. 1699-1707
    • Bergom, C.1    Goel, R.2    Paddock, C.3    Gao, C.4    Newman, D.K.5    Matsuyama, S.6
  • 22
    • 0035353204 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells
    • Guerriero, R., Mattia, G., Testa, U., Chelucci, C., Macioce, G., Casella, I., et al. (2001). Stromal cell-derived factor 1alpha increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells. Blood, 97, 2587-2595.
    • (2001) Blood , vol.97 , pp. 2587-2595
    • Guerriero, R.1    Mattia, G.2    Testa, U.3    Chelucci, C.4    Macioce, G.5    Casella, I.6
  • 23
    • 70649103096 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived stromal cells suppress xenogeneic immune cell response in vitro
    • Hao, L., Zhang, C., Chen, X. H., Zou, Z. M., Zhang, X., Kong, P. Y., et al. (2009). Human umbilical cord blood-derived stromal cells suppress xenogeneic immune cell response in vitro. Croatian Medical Journal, 50, 351-360.
    • (2009) Croatian Medical Journal , vol.50 , pp. 351-360
    • Hao, L.1    Zhang, C.2    Chen, X.H.3    Zou, Z.M.4    Zhang, X.5    Kong, P.Y.6
  • 24
    • 78650402526 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived stromal cells prevent graft-versus-host disease in mice following haplo-identical stem cell transplantation
    • Hao, L., Gao, L., Chen, X., Zou, Z., Zhang, X., Kong, P., et al. (2011). Human umbilical cord blood-derived stromal cells prevent graft-versus-host disease in mice following haplo-identical stem cell transplantation. Cytotherapy, 13, 83-91.
    • (2011) Cytotherapy , vol.13 , pp. 83-91
    • Hao, L.1    Gao, L.2    Chen, X.3    Zou, Z.4    Zhang, X.5    Kong, P.6
  • 25
    • 77955658462 scopus 로고    scopus 로고
    • Hypothesis: human umbilical cord blood-derived stromal cells promote megakaryocytopoiesis through the influence of SDF-1 and PECAM-1
    • Feng, Y., Chen, X., & Gao, L. (2010). Hypothesis: human umbilical cord blood-derived stromal cells promote megakaryocytopoiesis through the influence of SDF-1 and PECAM-1. Cell Biochemistry and Biophysics, 58, 25-30.
    • (2010) Cell Biochemistry and Biophysics , vol.58 , pp. 25-30
    • Feng, Y.1    Chen, X.2    Gao, L.3
  • 26
    • 0034141444 scopus 로고    scopus 로고
    • Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival
    • Lataillade, J. J., Clay, D., Dupuy, C., Rigal, S., Jasmin, C., Bourin, P., et al. (2000). Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood, 95, 756-768.
    • (2000) Blood , vol.95 , pp. 756-768
    • Lataillade, J.J.1    Clay, D.2    Dupuy, C.3    Rigal, S.4    Jasmin, C.5    Bourin, P.6
  • 27
    • 34547931490 scopus 로고    scopus 로고
    • PECAM-1: a multifaceted regulator of megakaryocytopoiesis
    • Wu, Y., Welte, T., Michaud, M., & Madri, J. A. (2007). PECAM-1: a multifaceted regulator of megakaryocytopoiesis. Blood, 110, 851-859.
    • (2007) Blood , vol.110 , pp. 851-859
    • Wu, Y.1    Welte, T.2    Michaud, M.3    Madri, J.A.4
  • 28
    • 1842483293 scopus 로고    scopus 로고
    • Chemokines and their receptors as therapeutic targets: the role of the SDF-1/CXCR4 axis
    • Juarez, J., Bendall, L., & Bradstock, K. (2004). Chemokines and their receptors as therapeutic targets: the role of the SDF-1/CXCR4 axis. Current Pharmaceutical Design, 10, 1245-1259.
    • (2004) Current Pharmaceutical Design , vol.10 , pp. 1245-1259
    • Juarez, J.1    Bendall, L.2    Bradstock, K.3
  • 29
    • 33750294009 scopus 로고    scopus 로고
    • The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis
    • Ratajczak, M., Zuba-Surma, E., Kucia, M., Reca, R., Wojakowski, W., & Ratajczak, J. (2006). The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis. Leukemia, 20, 1915-1924.
    • (2006) Leukemia , vol.20 , pp. 1915-1924
    • Ratajczak, M.1    Zuba-Surma, E.2    Kucia, M.3    Reca, R.4    Wojakowski, W.5    Ratajczak, J.6
  • 30
    • 0032929789 scopus 로고    scopus 로고
    • EGF stimulates tyrosine phosphorylation of focal adhesion kinase (p125FAK) and paxillin in rat pancreatic acini by a phospholipase C-independent process that depends on phosphatidylinositol 3-kinase, the small GTP-binding protein, p21rho, and the integrity of the actin cytoskeleton
    • Tapia, J. A., Camello, C., Jensen, R. T., & Garcia, L. J. (1999). EGF stimulates tyrosine phosphorylation of focal adhesion kinase (p125FAK) and paxillin in rat pancreatic acini by a phospholipase C-independent process that depends on phosphatidylinositol 3-kinase, the small GTP-binding protein, p21rho, and the integrity of the actin cytoskeleton. Biochimica et Biophysica Acta, 1448, 486-499.
    • (1999) Biochimica Et Biophysica Acta , vol.1448 , pp. 486-499
    • Tapia, J.A.1    Camello, C.2    Jensen, R.T.3    Garcia, L.J.4
  • 31
    • 0032483419 scopus 로고    scopus 로고
    • The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    • Ganju, R. K., Brubaker, S. A., Meyer, J., Dutt, P., Yang, Y., Qin, S., et al. (1998). The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. Journal of Biological Chemistry, 273, 23169-23175.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3    Dutt, P.4    Yang, Y.5    Qin, S.6
  • 33
    • 78651328424 scopus 로고    scopus 로고
    • PI3 kinase-dependent stimulation of platelet migration by stromal cell-derived factor 1 (SDF-1)
    • Kraemer, B., Borst, O., Gehring, E., Schoenberger, T., Urban, B., Ninci, E., et al. (2010). PI3 kinase-dependent stimulation of platelet migration by stromal cell-derived factor 1 (SDF-1). Journal of Molecular Medicine, 88, 1277-1288.
    • (2010) Journal of Molecular Medicine , vol.88 , pp. 1277-1288
    • Kraemer, B.1    Borst, O.2    Gehring, E.3    Schoenberger, T.4    Urban, B.5    Ninci, E.6
  • 34
    • 0034016785 scopus 로고    scopus 로고
    • Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT
    • Majka, M., Ratajczak, J., Kowalska, M. A., & Ratajczak, M. Z. (2000). Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT. European Journal of Haematology, 64, 164-172.
    • (2000) European Journal of Haematology , vol.64 , pp. 164-172
    • Majka, M.1    Ratajczak, J.2    Kowalska, M.A.3    Ratajczak, M.Z.4
  • 35
    • 0034672371 scopus 로고    scopus 로고
    • Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis
    • Majka, M., Janowska-Wieczorek, A., Ratajczak, J., Kowalska, M. A., Vilaire, G., Pan, Z. K., et al. (2000). Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. Blood, 96, 4142-4151.
    • (2000) Blood , vol.96 , pp. 4142-4151
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3    Kowalska, M.A.4    Vilaire, G.5    Pan, Z.K.6
  • 36
    • 0035874498 scopus 로고    scopus 로고
    • Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner
    • Majka, M., Janowska-Wieczorek, A., Ratajczak, J., Ehrenman, K., Pietrzkowski, Z., Kowalska, M. A., et al. (2001). Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood, 97, 3075-3085.
    • (2001) Blood , vol.97 , pp. 3075-3085
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3    Ehrenman, K.4    Pietrzkowski, Z.5    Kowalska, M.A.6
  • 37
    • 0037431021 scopus 로고    scopus 로고
    • The unfolding tale of PECAM-1
    • Jackson, D. E. (2003). The unfolding tale of PECAM-1. FEBS Letters, 540, 7-14.
    • (2003) FEBS Letters , vol.540 , pp. 7-14
    • Jackson, D.E.1
  • 38
    • 34147134626 scopus 로고    scopus 로고
    • Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training
    • Wadley, G. D., Konstantopoulos, N., Macaulay, L., Howlett, K. F., Garnham, A., Hargreaves, M., et al. (2007). Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training. Journal of Applied Physiology, 102, 1624-1631.
    • (2007) Journal of Applied Physiology , vol.102 , pp. 1624-1631
    • Wadley, G.D.1    Konstantopoulos, N.2    Macaulay, L.3    Howlett, K.F.4    Garnham, A.5    Hargreaves, M.6
  • 39
    • 34247221517 scopus 로고    scopus 로고
    • The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation
    • Laramee, M., Chabot, C., Cloutier, M., Stenne, R., Holgado-Madruga, M., Wong, A. J., et al. (2007). The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation. Journal of Biological Chemistry, 282, 7758-7769.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 7758-7769
    • Laramee, M.1    Chabot, C.2    Cloutier, M.3    Stenne, R.4    Holgado-Madruga, M.5    Wong, A.J.6
  • 40
    • 33751084570 scopus 로고    scopus 로고
    • Modulation of alpha-catenin Tyr phosphorylation by SHP2 positively effects cell transformation induced by the constitutively active FGFR3
    • Burks, J., & Agazie, Y. M. (2006). Modulation of alpha-catenin Tyr phosphorylation by SHP2 positively effects cell transformation induced by the constitutively active FGFR3. Oncogene, 25, 7166-7179.
    • (2006) Oncogene , vol.25 , pp. 7166-7179
    • Burks, J.1    Agazie, Y.M.2
  • 42
    • 1842525884 scopus 로고    scopus 로고
    • SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis
    • Ivins Zito, C., Kontaridis, M. I., Fornaro, M., Feng, G. S., & Bennett, A. M. (2004). SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis. Journal of Cellular Physiology, 199, 227-236.
    • (2004) Journal of Cellular Physiology , vol.199 , pp. 227-236
    • Ivins Zito, C.1    Kontaridis, M.I.2    Fornaro, M.3    Feng, G.S.4    Bennett, A.M.5
  • 43
    • 22344440360 scopus 로고    scopus 로고
    • Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2
    • Haider, U. G., Roos, T. U., Kontaridis, M. I., Neel, B. G., Sorescu, D., Griendling, K. K., et al. (2005). Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2. Molecular Pharmacology, 68, 41-48.
    • (2005) Molecular Pharmacology , vol.68 , pp. 41-48
    • Haider, U.G.1    Roos, T.U.2    Kontaridis, M.I.3    Neel, B.G.4    Sorescu, D.5    Griendling, K.K.6
  • 44
    • 34748831102 scopus 로고    scopus 로고
    • The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury
    • Chong, Z. Z., & Maiese, K. (2007). The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury. Histology and Histopathology, 22, 1251-1267.
    • (2007) Histology and Histopathology , vol.22 , pp. 1251-1267
    • Chong, Z.Z.1    Maiese, K.2
  • 45
    • 0033965899 scopus 로고    scopus 로고
    • Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity
    • Shi, Z. Q., Yu, D. H., Park, M., Marshall, M., & Feng, G. S. (2000). Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Molecular and Cellular Biology, 20, 1526-1536.
    • (2000) Molecular and Cellular Biology , vol.20 , pp. 1526-1536
    • Shi, Z.Q.1    Yu, D.H.2    Park, M.3    Marshall, M.4    Feng, G.S.5
  • 46
  • 47
    • 3543036342 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
    • Yu, D. H., Qu, C. K., Henegariu, O., Lu, X., & Feng, G. S. (1998). Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. Journal of Biological Chemistry, 273, 21125-21131.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 21125-21131
    • Yu, D.H.1    Qu, C.K.2    Henegariu, O.3    Lu, X.4    Feng, G.S.5
  • 48
    • 0032877293 scopus 로고    scopus 로고
    • PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated β-catenin
    • Ilan, N., Mahooti, S., Rimm, D. L., & Madri, J. A. (1999). PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated β-catenin. Journal of Cell Science, 112(Pt 18), 3005-3014.
    • (1999) Journal of Cell Science , vol.112 , Issue.Pt 18 , pp. 3005-3014
    • Ilan, N.1    Mahooti, S.2    Rimm, D.L.3    Madri, J.A.4
  • 49
    • 0034647532 scopus 로고    scopus 로고
    • Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation
    • Ilan, N., Cheung, L., Pinter, E., & Madri, J. A. (2000). Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation. Journal of Biological Chemistry, 275, 21435-21443.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 21435-21443
    • Ilan, N.1    Cheung, L.2    Pinter, E.3    Madri, J.A.4
  • 50
    • 79952653707 scopus 로고    scopus 로고
    • Hematopoietic stromal cells and megakaryocyte development
    • Feng, Y., Gao, L., & Chen, X. (2011). Hematopoietic stromal cells and megakaryocyte development. Hematology, 16, 67-72.
    • (2011) Hematology , vol.16 , pp. 67-72
    • Feng, Y.1    Gao, L.2    Chen, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.