Regulation of megakaryocytopoiesis by thrombopoietin and stromal cells

Leukemia

Volumn 11, Issue SUPPL. 3, 1997, Pages 435-438

  Nagata, Yuka ^a   Nagahisa, Hiroshi ^a   Nagasawa, Toshiro ^a   Todokoro, Kazuo ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; THROMBOPOIETIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; BONE MARROW CELL; CELL ADHESION; CELL MATURATION; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STROMA CELL; THROMBOCYTOPENIA; THROMBOSIS; TISSUE DISTRIBUTION;

EID: 0030878970     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. de Sauvage FJ et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature, 1994; 369: 533-538.
2. Lok S et al. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature, 1994; 369; 565-568.
3. Kaushansky K et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature, 1994; 369: 568-571.
4. Wendling F et al. c-Mpl ligand is a humoral regulator of megakaryocytopoiesis. Nature, 1994; 369: 571-574.
5. Bartley TD. et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl Cell, 1994; 77: 1117-1124.
6. Nagata Y et al. submitted.
7. Nagahisa H et al. Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation. Blood, in press.
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9. Nagata Y et al. Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cell. J Biol Chem 1995; 270: 19673-19675.
10. Wada T et al. Characterization of the truncated thrombopoietin variants. Biochem Biophys Res Commun, 1995; 213: 1091-1098.