Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia

Journal of Proteomics

Volumn 75, Issue 17, 2012, Pages 5449-5462

  Izquierdo Álvarez, Alicia ^a   Ramos, Elena ^a   Villanueva, Joan ^b   Hernansanz Agustín, Pablo ^a   Fernández Rodríguez, Rubén ^a,c   Tello, Daniel ^a   Carrascal, Montserrat ^b   Martínez Ruiz, Antonio ^a  

^a Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^b INST D INVESTIGACIONS B   (Spain)

^c University of Granada   (Spain)

Author keywords

Cell signaling; Cysteine oxidation; Post translational modifications; Redox fluorescence switch (RFS); Thiol redox proteomics; Two dimensional electrophoresis (2 DE)

Indexed keywords

CYSTEINE; HYPOXIA INDUCIBLE FACTOR; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL HYPOXIA; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; REDOX FLUORESCENCE SWITCH; REOXYGENATION; TWO DIMENSIONAL ELECTROPHORESIS;

CELL HYPOXIA; CELLS, CULTURED; CYSTEINE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; PROTEOMICS; REACTIVE OXYGEN SPECIES; STRESS, PHYSIOLOGICAL; SULFHYDRYL COMPOUNDS; TIME FACTORS;

METAZOA;

EID: 84865540710     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2012.06.035     Document Type: Article

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