Identification of Chemical Inhibitors to Human Tissue Transglutaminase by Screening Existing Drug Libraries

Chemistry and Biology

Volumn 15, Issue 9, 2008, Pages 969-978

  Lai, Thung S ^a   Liu, Yusha ^a   Tucker, Tim ^a   Daniel, Kurt R ^b   Sane, David C ^b   Toone, Eric ^c   Burke, James R ^a   Strittmatter, Warren J ^a   Greenberg, Charles S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

CELLBIO; CHEMBIO

Indexed keywords

BLOOD CLOTTING FACTOR 13A; CALCIUM; ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATE; NAPHTHOQUINONE; OCTOXINOL; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TISSUE TRANSGLUTAMINASE 2, HUMAN; TYRPHOSTIN;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DISEASE MODEL; DROSOPHILA MELANOGASTER; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; HUMAN; MACHADO JOSEPH DISEASE; METABOLISM;

ANIMALS; CALCIUM; COMBINATORIAL CHEMISTRY TECHNIQUES; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FACTOR XIIIA; GUANOSINE TRIPHOSPHATE; HUMANS; MACHADO-JOSEPH DISEASE; MOLECULAR STRUCTURE; NAPHTHOQUINONES; OCTOXYNOL; TRANSGLUTAMINASES; TYRPHOSTINS;

EID: 51649127246     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2008.07.015     Document Type: Article

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