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Volumn 75, Issue 17, 2012, Pages 5215-5225

Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach

Author keywords

Conopeptides; Conotoxins; Conus venom; Peptidomics; Transcriptomics

Indexed keywords

ACTINOPORIN; CONKUNITZIN; CONOPEPTIDE; CONOPORIN; CONOPROTEIN; CONOTOXIN; HYALURONIDASE; HYDROXYPROLINE; MEMBRANE PROTEIN; MESSENGER RNA; METHIONINE; PEPTIDE DERIVATIVE; SNAIL VENOM; UNCLASSIFIED DRUG;

EID: 84865539150     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2012.06.001     Document Type: Article
Times cited : (73)

References (42)
  • 1
    • 70349414436 scopus 로고    scopus 로고
    • Marine snail venoms: use and trends in receptor and channel neuropharmacology
    • Favreau P., Stocklin R. Marine snail venoms: use and trends in receptor and channel neuropharmacology. Curr Opin Pharmacol 2009, 9:594-601.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 594-601
    • Favreau, P.1    Stocklin, R.2
  • 2
    • 17644403453 scopus 로고    scopus 로고
    • Molecular prospecting for drugs from the sea. Isolating therapeutic peptides and proteins from cone snail venom
    • Gayler K., Sandall D., Greening D., Keays D., Polidano M., Livett B., et al. Molecular prospecting for drugs from the sea. Isolating therapeutic peptides and proteins from cone snail venom. IEEE Eng Med Biol Mag 2005, 24:79-84.
    • (2005) IEEE Eng Med Biol Mag , vol.24 , pp. 79-84
    • Gayler, K.1    Sandall, D.2    Greening, D.3    Keays, D.4    Polidano, M.5    Livett, B.6
  • 3
    • 67649592405 scopus 로고    scopus 로고
    • Conotoxins: natural product drug leads
    • Halai R., Craik D.J. Conotoxins: natural product drug leads. Nat Prod Rep 2009, 26:526-536.
    • (2009) Nat Prod Rep , vol.26 , pp. 526-536
    • Halai, R.1    Craik, D.J.2
  • 4
    • 57049092282 scopus 로고    scopus 로고
    • Marine genetic resources: a review of scientific and commercial interest
    • Leary D., Vierros M., Hamon G.l., Arico S., Monagle C. Marine genetic resources: a review of scientific and commercial interest. Mar Policy 2009, 33:183-194.
    • (2009) Mar Policy , vol.33 , pp. 183-194
    • Leary, D.1    Vierros, M.2    Hamon, G.3    Arico, S.4    Monagle, C.5
  • 6
    • 84874442131 scopus 로고    scopus 로고
    • Pharmacological characterization of a novel mu-conopeptide, CnIIIC, indicates potent and preferential inhibition of sodium channel subtypes (Na(V) 1.2/1.4) and reveals unusual activity on neuronal nicotinic acetylcholine receptors. Br J Pharmacol in press
    • Favreau P, Benoit E, Hocking HG, Carlier L, D'hoedt D, Leipold E, et al. Pharmacological characterization of a novel mu-conopeptide, CnIIIC, indicates potent and preferential inhibition of sodium channel subtypes (Na(V) 1.2/1.4) and reveals unusual activity on neuronal nicotinic acetylcholine receptors. Br J Pharmacol in press.
    • Favreau, P.1    Benoit, E.2    Hocking, H.G.3    Carlier, L.4    D'hoedt, D.5    Leipold, E.6
  • 7
    • 52949118506 scopus 로고    scopus 로고
    • Conus venoms - a rich source of peptide-based therapeutics
    • Han T.S., Teichert R.W., Olivera B.M., Bulaj G. Conus venoms - a rich source of peptide-based therapeutics. Curr Pharm Des 2008, 14:2462-2479.
    • (2008) Curr Pharm Des , vol.14 , pp. 2462-2479
    • Han, T.S.1    Teichert, R.W.2    Olivera, B.M.3    Bulaj, G.4
  • 8
    • 84857049157 scopus 로고    scopus 로고
    • Discovery and development of the chi-conopeptide class of analgesic peptides
    • Lewis R.J. Discovery and development of the chi-conopeptide class of analgesic peptides. Toxicon 2012, 59:524-528.
    • (2012) Toxicon , vol.59 , pp. 524-528
    • Lewis, R.J.1
  • 9
    • 34249017949 scopus 로고    scopus 로고
    • Ziconotide: a review of its pharmacology and use in the treatment of pain
    • McGivern J.G. Ziconotide: a review of its pharmacology and use in the treatment of pain. Neuropsychiatr Dis Treat 2007, 3:69-85.
    • (2007) Neuropsychiatr Dis Treat , vol.3 , pp. 69-85
    • McGivern, J.G.1
  • 10
    • 9144272640 scopus 로고    scopus 로고
    • Ziconotide: neuronal calcium channel blocker for treating severe chronic pain
    • Miljanich G.P. Ziconotide: neuronal calcium channel blocker for treating severe chronic pain. Curr Med Chem 2004, 11:3029-3040.
    • (2004) Curr Med Chem , vol.11 , pp. 3029-3040
    • Miljanich, G.P.1
  • 11
    • 60249089640 scopus 로고    scopus 로고
    • Comparative proteomic study of the venom of the piscivorous cone snail Conus consors
    • Biass D., Dutertre S., Gerbault A., Menou J.L., Offord R., Favreau P., et al. Comparative proteomic study of the venom of the piscivorous cone snail Conus consors. J Proteomics 2009, 72:210-218.
    • (2009) J Proteomics , vol.72 , pp. 210-218
    • Biass, D.1    Dutertre, S.2    Gerbault, A.3    Menou, J.L.4    Offord, R.5    Favreau, P.6
  • 12
    • 67349175001 scopus 로고    scopus 로고
    • Remarkable inter- and intra-species complexity of conotoxins revealed by LC/MS
    • Davis J., Jones A., Lewis R.J. Remarkable inter- and intra-species complexity of conotoxins revealed by LC/MS. Peptides 2009, 30:1222-1227.
    • (2009) Peptides , vol.30 , pp. 1222-1227
    • Davis, J.1    Jones, A.2    Lewis, R.J.3
  • 13
    • 80052446687 scopus 로고    scopus 로고
    • Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway
    • Safavi-Hemami H., Siero W.A., Gorasia D.G., Young N.D., Macmillan D., Williamson N.A., et al. Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway. J Proteome Res 2011, 10:3904-3919.
    • (2011) J Proteome Res , vol.10 , pp. 3904-3919
    • Safavi-Hemami, H.1    Siero, W.A.2    Gorasia, D.G.3    Young, N.D.4    Macmillan, D.5    Williamson, N.A.6
  • 14
    • 77952068729 scopus 로고    scopus 로고
    • Proteomic analysis provides insights on venom processing in Conus textile
    • Tayo L.L., Lu B., Cruz L.J., Yates J.R. Proteomic analysis provides insights on venom processing in Conus textile. J Proteome Res 2010, 9:2292-2301.
    • (2010) J Proteome Res , vol.9 , pp. 2292-2301
    • Tayo, L.L.1    Lu, B.2    Cruz, L.J.3    Yates, J.R.4
  • 15
    • 77952243217 scopus 로고    scopus 로고
    • Dramatic intraspecimen variations within the injected venom of Conus consors: an unsuspected contribution to venom diversity
    • Dutertre S., Biass D., Stocklin R., Favreau P. Dramatic intraspecimen variations within the injected venom of Conus consors: an unsuspected contribution to venom diversity. Toxicon 2010, 55:1453-1462.
    • (2010) Toxicon , vol.55 , pp. 1453-1462
    • Dutertre, S.1    Biass, D.2    Stocklin, R.3    Favreau, P.4
  • 17
    • 0032795276 scopus 로고    scopus 로고
    • Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns
    • Olivera B.M., Walker C., Cartier G.E., Hooper D., Santos A.D., Schoenfeld R., et al. Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns. Ann N Y Acad Sci 1999, 870:223-237.
    • (1999) Ann N Y Acad Sci , vol.870 , pp. 223-237
    • Olivera, B.M.1    Walker, C.2    Cartier, G.E.3    Hooper, D.4    Santos, A.D.5    Schoenfeld, R.6
  • 19
    • 13044283060 scopus 로고    scopus 로고
    • Molecular genetics of ecological diversification: duplication and rapid evolution of toxin genes of the venomous gastropod Conus
    • Duda T.F., Palumbi S.R. Molecular genetics of ecological diversification: duplication and rapid evolution of toxin genes of the venomous gastropod Conus. Proc Natl Acad Sci U S A 1999, 96:6820-6823.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6820-6823
    • Duda, T.F.1    Palumbi, S.R.2
  • 20
    • 27944494442 scopus 로고    scopus 로고
    • Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins
    • Pi C., Liu Y., Peng C., Jiang X., Liu J., Xu B., et al. Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins. Biochimie 2006, 88:131-140.
    • (2006) Biochimie , vol.88 , pp. 131-140
    • Pi, C.1    Liu, Y.2    Peng, C.3    Jiang, X.4    Liu, J.5    Xu, B.6
  • 21
    • 33751118759 scopus 로고    scopus 로고
    • Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus
    • Pi C., Liu J., Peng C., Liu Y., Jiang X., Zhao Y., et al. Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus. Genomics 2006, 88:809-819.
    • (2006) Genomics , vol.88 , pp. 809-819
    • Pi, C.1    Liu, J.2    Peng, C.3    Liu, Y.4    Jiang, X.5    Zhao, Y.6
  • 23
    • 78951484618 scopus 로고    scopus 로고
    • Characterization of the Conus bullatus genome and its venom-duct transcriptome
    • Hu H., Bandyopadhyay P.K., Olivera B.M., Yandell M. Characterization of the Conus bullatus genome and its venom-duct transcriptome. BMC Genomics 2011, 12:60.
    • (2011) BMC Genomics , vol.12 , pp. 60
    • Hu, H.1    Bandyopadhyay, P.K.2    Olivera, B.M.3    Yandell, M.4
  • 24
    • 81155148629 scopus 로고    scopus 로고
    • High-resolution picture of a venom gland transcriptome: case study with the marine snail Conus consors
    • Terrat Y., Biass D., Dutertre S., Favreau P., Remm M., Stocklin R., et al. High-resolution picture of a venom gland transcriptome: case study with the marine snail Conus consors. Toxicon 2012, 59:34-46.
    • (2012) Toxicon , vol.59 , pp. 34-46
    • Terrat, Y.1    Biass, D.2    Dutertre, S.3    Favreau, P.4    Remm, M.5    Stocklin, R.6
  • 25
    • 0029080121 scopus 로고
    • A new family of Conus peptides targeted to the nicotinic acetylcholine receptor
    • Hopkins C., Grilley M., Miller C., Shon K.J., Cruz L.J., Gray W.R., et al. A new family of Conus peptides targeted to the nicotinic acetylcholine receptor. J Biol Chem 1995, 270:22361-22367.
    • (1995) J Biol Chem , vol.270 , pp. 22361-22367
    • Hopkins, C.1    Grilley, M.2    Miller, C.3    Shon, K.J.4    Cruz, L.J.5    Gray, W.R.6
  • 26
    • 60149091267 scopus 로고    scopus 로고
    • TxXIIIA, an atypical homodimeric conotoxin found in the Conus textile venom
    • Quinton L., Gilles N., De P.E. TxXIIIA, an atypical homodimeric conotoxin found in the Conus textile venom. J Proteomics 2009, 72:219-226.
    • (2009) J Proteomics , vol.72 , pp. 219-226
    • Quinton, L.1    Gilles, N.2    De, P.E.3
  • 27
    • 33751049816 scopus 로고    scopus 로고
    • Conotoxins down under
    • Norton R.S., Olivera B.M. Conotoxins down under. Toxicon 2006, 48:780-798.
    • (2006) Toxicon , vol.48 , pp. 780-798
    • Norton, R.S.1    Olivera, B.M.2
  • 30
    • 0033545910 scopus 로고    scopus 로고
    • Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors
    • Favreau P., Krimm I., Le G.F., Bobenrieth M.J., Lamthanh H., Bouet F., et al. Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors. Biochemistry 1999, 38:6317-6326.
    • (1999) Biochemistry , vol.38 , pp. 6317-6326
    • Favreau, P.1    Krimm, I.2    Le, G.F.3    Bobenrieth, M.J.4    Lamthanh, H.5    Bouet, F.6
  • 32
    • 0025788030 scopus 로고
    • Effects of amino acid sequence, buffers, and ionic strength on the rate and mechanism of deamidation of asparagine residues in small peptides
    • Tyler-Cross R., Schirch V. Effects of amino acid sequence, buffers, and ionic strength on the rate and mechanism of deamidation of asparagine residues in small peptides. J Biol Chem 1991, 266:22549-22556.
    • (1991) J Biol Chem , vol.266 , pp. 22549-22556
    • Tyler-Cross, R.1    Schirch, V.2
  • 34
    • 33750054370 scopus 로고    scopus 로고
    • Characterization of novel M-superfamily conotoxins with new disulfide linkage
    • Han Y.H., Wang Q., Jiang H., Liu L., Xiao C., Yuan D.D., et al. Characterization of novel M-superfamily conotoxins with new disulfide linkage. FEBS J 2006, 273:4972-4982.
    • (2006) FEBS J , vol.273 , pp. 4972-4982
    • Han, Y.H.1    Wang, Q.2    Jiang, H.3    Liu, L.4    Xiao, C.5    Yuan, D.D.6
  • 35
    • 70349623944 scopus 로고    scopus 로고
    • Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents
    • Wang L., Liu J., Pi C., Zeng X., Zhou M., Jiang X., et al. Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents. Arch Toxicol 2009, 83:925-932.
    • (2009) Arch Toxicol , vol.83 , pp. 925-932
    • Wang, L.1    Liu, J.2    Pi, C.3    Zeng, X.4    Zhou, M.5    Jiang, X.6
  • 36
    • 0030973424 scopus 로고    scopus 로고
    • Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues
    • Lew M.J., Flinn J.P., Pallaghy P.K., Murphy R., Whorlow S.L., Wright C.E., et al. Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues. J Biol Chem 1997, 272:12014-12023.
    • (1997) J Biol Chem , vol.272 , pp. 12014-12023
    • Lew, M.J.1    Flinn, J.P.2    Pallaghy, P.K.3    Murphy, R.4    Whorlow, S.L.5    Wright, C.E.6
  • 37
    • 21244493712 scopus 로고    scopus 로고
    • Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization
    • Bayrhuber M., Vijayan V., Ferber M., Graf R., Korukottu J., Imperial J., et al. Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. J Biol Chem 2005, 280:23766-23770.
    • (2005) J Biol Chem , vol.280 , pp. 23766-23770
    • Bayrhuber, M.1    Vijayan, V.2    Ferber, M.3    Graf, R.4    Korukottu, J.5    Imperial, J.6
  • 38
    • 84858205449 scopus 로고    scopus 로고
    • Recruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms
    • Violette A., Leonardi A., Piquemal D., Terrat Y., Biass D., Dutertre S., et al. Recruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms. Mar Drugs 2012, 10:258-280.
    • (2012) Mar Drugs , vol.10 , pp. 258-280
    • Violette, A.1    Leonardi, A.2    Piquemal, D.3    Terrat, Y.4    Biass, D.5    Dutertre, S.6
  • 39
    • 33645372800 scopus 로고    scopus 로고
    • Hyaluronidases: their genomics, structures, and mechanisms of action
    • Stern R., Jedrzejas M.J. Hyaluronidases: their genomics, structures, and mechanisms of action. Chem Rev 2006, 106:818-839.
    • (2006) Chem Rev , vol.106 , pp. 818-839
    • Stern, R.1    Jedrzejas, M.J.2
  • 40
    • 1542496676 scopus 로고    scopus 로고
    • Primary structure of echotoxin 2, an actinoporin-like hemolytic toxin from the salivary gland of the marine gastropod Monoplex echo
    • Kawashima Y., Nagai H., Ishida M., Nagashima Y., Shiomi K. Primary structure of echotoxin 2, an actinoporin-like hemolytic toxin from the salivary gland of the marine gastropod Monoplex echo. Toxicon 2003, 42:491-497.
    • (2003) Toxicon , vol.42 , pp. 491-497
    • Kawashima, Y.1    Nagai, H.2    Ishida, M.3    Nagashima, Y.4    Shiomi, K.5
  • 41
    • 0036161949 scopus 로고    scopus 로고
    • Properties of proteinaceous toxins in the salivary gland of the marine gastropod (Monoplex echo)
    • Shiomi K., Kawashima Y., Mizukami M., Nagashima Y. Properties of proteinaceous toxins in the salivary gland of the marine gastropod (Monoplex echo). Toxicon 2002, 40:563-571.
    • (2002) Toxicon , vol.40 , pp. 563-571
    • Shiomi, K.1    Kawashima, Y.2    Mizukami, M.3    Nagashima, Y.4
  • 42
    • 0033198875 scopus 로고    scopus 로고
    • Post-translationally modified neuropeptides from Conus venoms
    • Craig A.G., Bandyopadhyay P., Olivera B.M. Post-translationally modified neuropeptides from Conus venoms. Eur J Biochem 1999, 264:271-275.
    • (1999) Eur J Biochem , vol.264 , pp. 271-275
    • Craig, A.G.1    Bandyopadhyay, P.2    Olivera, B.M.3


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