Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family: Structural and functional characterization

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 23766-23770

  Bayrhuber, Monika ^a   Vijayan, Vinesh ^a   Ferber, Michael ^b   Graf, Roland ^a   Korukottu, Jegannath ^a   Imperial, Julita ^c   Garrett, James E ^d   Olivera, Baldomero M ^c   Terlau, Heinrich ^b   Zweckstetter, Markus ^a   Becker, Stefan ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^c UNIVERSITY OF UTAH   (United States)

^d Cognetix Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHARACTERIZATION; CROSSLINKING; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POTASSIUM; PROTEINS;

FUNCTIONAL CHARACTERIZATION; NEUROTOXIN; PORE MUTATION;

TOXICITY;

NEUROTOXIN; PROTEIN CONKUNITZIN S1; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CROSS LINKING; DISULFIDE BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLLUSK VENOMS; NEUROTOXINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

CONUS STRIATUS; GASTROPODA;

EID: 21244493712     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C500064200     Document Type: Article

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