Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents

Archives of Toxicology

Volumn 83, Issue 10, 2009, Pages 925-932

  Wang, Lei ^a   Liu, Junliang ^a   Pi, Canhui ^a   Zeng, Xiayun ^a   Zhou, Maojun ^a   Jiang, Xiaoyu ^a   Chen, Shangwu ^a   Ren, Zhenghua ^a   Xu, Anlong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Conus litteratus; M superfamily conotoxin; Post translational modification; Rat dorsal root ganglion neurons; Tetrodotoxin sensitive sodium channels

Indexed keywords

COMPLEMENTARY DNA; CONOTOXIN; CONOTOXIN M; GLUTAMIC ACID DERIVATIVE; HYDROXYPROLINE; SODIUM; TETRODOTOXIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONUS LITTERATUS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN PROCESSING; PURIFICATION; RAT; SNAIL; SODIUM CURRENT; SPINAL CORD NERVE CELL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CONOTOXINS; CONUS SNAIL; ELECTRIC CONDUCTIVITY; EXPRESSED SEQUENCE TAGS; GANGLIA, SPINAL; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TETRODOTOXIN;

CONUS LITTERATUS; RATTUS;

EID: 70349623944     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-009-0453-8     Document Type: Article

References (22)

1. O Buczek G Bulaj BM Olivera 2005 Conotoxins and the posttranslational modification of secreted gene products Cell Mol Life Sci 62 3067 3079 16314929 10.1007/s00018-005-5283-0 1:CAS:528:DC%2BD28Xms1Gqsg%3D%3D (Pubitemid 43004755)
2. G Bulaj O Buczek I Goodsell EC Jimenez J Kranski JS Nielsen JE Garrett BM Olivera 2003 Efficient oxidative folding of conotoxins and the radiation of venomous cone snails Proc Natl Acad Sci USA 100 Suppl 2 14562 14568 14573706 10.1073/pnas.2335845100 1:CAS:528:DC%2BD3sXpsFaku7w%3D
3. S Cestèle WA Catterall 2000 Molecular mechanisms of neurotoxin action on voltage-gated sodium channels Biochimie 82 883 892 11086218 10.1016/S0300-9084(00)01174-3 (Pubitemid 30843369)
4. GP Corpuz RB Jacobsen EC Jimenez M Watkins C Walker C Colledge JE Garrett O McDougal W Li WR Gray DR Hillyard J Rivier JM McIntosh LJ Cruz BM Olivera 2005 Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms Biochemistry 44 8176 8186 15924437 10.1021/bi047541b 1:CAS:528:DC%2BD2MXktVKls7c%3D (Pubitemid 40776679)
5. J Ekberg DJ Adams 2006 Neuronal voltage-gated sodium channel subtypes: key roles in inflammatory and neuropathic pain Int J Biochem Cell Biol 38 12 2005 2010 16919992 10.1016/j.biocel.2006.06.008 1:CAS:528:DC%2BD28XpvFSjur0%3D (Pubitemid 44397622)
6. J Ekberg DJ Craik DJ Adams 2008 Conotoxin modulation of voltage-gated sodium channels Int J Biochem Cell Biol 40 11 2363 2368 17951097 10.1016/j.biocel.2007.08.017 1:CAS:528:DC%2BD1cXpsVagtbY%3D
7. GJ Gross DC Warltier HF Hardman S Shibata 1985 Cardiotonic effects of anthopleurin-A (AP-A), a polypeptide from a sea anemone, in dogs with a coronary artery stenosis Eur J Pharmacol 110 2 271 276 3987818 10.1016/0014-2999(85) 90223-7 1:CAS:528:DyaL2MXitFCqsbg%3D (Pubitemid 15074384)
8. NA Hagen KM Fisher B Lapointe P du Souich S Chary D Moulin E Sellers AH Ngoc Canadian Tetrodotoxin Study Group 2007 An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain J Pain Symptom Manage 34 2 171 182 17662911 10.1016/j.jpainsymman.2006.11.008 1:CAS:528:DC%2BD2sXhtVeitbfE (Pubitemid 47096781)
9. YH Han Q Wang H Jiang L Liu C Xiao DD Yuan XX Shao QY Dai JS Cheng CW Chi 2006 Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J 273 4972 4982 17042781 10.1111/j.1742-4658.2006.05493.x 1:CAS:528:DC%2BD28Xht1Grt7%2FF (Pubitemid 44583519)
10. JA Jakubowski DA Keays WP Kelley dW Sandall JP Bingham BG Livett KR Gayler JV Sweedler 2004 Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry J Mass Spectrom 39 548 557 15170751 10.1002/jms.624 1:CAS:528:DC%2BD2cXktlOrsrk%3D (Pubitemid 38714820)
11. JA Jakubowski WP Kelley JV Sweedler 2006 Screening for post-translational modifications in conotoxins using liquid chromatography/mass spectrometry: an important component of conotoxin discovery Toxicon 47 688 699 16574181 10.1016/j.toxicon.2006.01.021 1:CAS:528:DC%2BD28XktVWntbc%3D
12. H Jiang CZ Wang CQ Xu CX Fan XD Dai JS Chen CW Chi 2006 A novel M-superfamily conotoxin with a unique motif from Conus vexillum Peptides 27 682 689 16181706 10.1016/j.peptides.2005.08.004 1:CAS:528:DC%2BD28XjtFWru7s%3D
13. RJ Lewis ML Garcia 2003 Therapeutic potential of venom peptides Nat Rev Drug Discov 2 10 790 802 14526382 10.1038/nrd1197 1:CAS:528:DC%2BD3sXnslarsb4%3D
14. J Liu Q Wu C Pi Y Zhao M Zhou L Wang S Chen A Xu 2007 Isolation and characterization of a T-superfamily conotoxin from Conus litteratus with targeting tetrodotoxin-sensitive sodium channels Peptides 28 2313 2319 17961831 10.1016/j.peptides.2007.09.006 1:CAS:528:DC%2BD2sXhtlCqsrrE (Pubitemid 350123559)
15. Gm Nicholson R Walsh MJ Little MI Tyler 1998 Characterization of the effects of robustoxin, the lethal neurotoxin from the Sydney funnel-web spider Atrax robustus, on sodium channel activation and inactivation Pflugers Arch 436 117 126 9560455 10.1007/s004240050612 1:CAS:528:DyaK1cXitlyjsL0%3D (Pubitemid 28206324)
16. BMEE Olivera 1997 Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology Mol Biol Cell 8 2101 2109 9362055 1:CAS:528:DyaK2sXntFylu7c%3D
17. BM Olivera 2006 Conus peptides: biodiversity-based discovery and exogenomics JBC 81 31173 31177 10.1074/jbc.R600020200 (Pubitemid 46041381)
18. BM Olivera LJ Cruz 2004 Conotoxins, in retrospect Toxicon 39 7 14 10.1016/S0041-0101(00)00157-4
19. C Pi J Liu C Peng Y Liu X Jiang Y Zhao S Tang L Wang M Dong S Chen A Xu 2006 Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus Genomics 88 809 819 16908117 10.1016/j.ygeno.2006.06.014 1:CAS:528:DC%2BD28Xht1WmsrzJ (Pubitemid 44768064)
20. J Shi TT Liu X Wang DH Epstein LY Zhao XL Zhang L Lu 2009 Tetrodotoxin reduces cue-induced drug craving and anxiety in abstinent heroin addicts Pharmacol Biochem Behav 92 4 603 607 19268686 10.1016/j.pbb.2009.02.013 1:CAS:528:DC%2BD1MXltlaqtrc%3D
21. H Terlau BM Olivera 2004 Conus venoms: a rich source of novel ion channel-targeted peptides Physiol Rev 84 41 68 14715910 10.1152/physrev.00020. 2003 1:CAS:528:DC%2BD2cXotl2rtA%3D%3D (Pubitemid 38049875)
22. MJ Wang SH Xiong ZW Li 2001 Neurokinin B potentiates ATP-activated currents in rat DRG neurons Brain Res 923 157 162 11743983 10.1016/S0006- 8993(01)03211-5 1:CAS:528:DC%2BD3MXovF2jsbw%3D (Pubitemid 34024947)