메뉴 건너뛰기




Volumn 287, Issue 35, 2012, Pages 29543-29553

Assessment of anti-recombination and double-strand break-induced gene conversion in human cells by a chromosomal reporter

Author keywords

[No Author keywords available]

Indexed keywords

ASSAY SYSTEM; CANCER CELLS; DISTAL REGIONS; DOUBLE-STRAND BREAKS; GENE CONVERSION; HETERODUPLEX; HOMOLOGOUS RECOMBINATION; HUMAN CELLS; STRAND ANNEALING; SURROUNDING REGIONS; TUMOR SUPPRESSOR GENES;

EID: 84865511730     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.352302     Document Type: Article
Times cited : (10)

References (52)
  • 1
    • 29244437908 scopus 로고    scopus 로고
    • The role of double-strand break repair: Insights from human genetics
    • O'Driscoll, M., and Jeggo, P. A. (2006) The role of double-strand break repair: Insights from human genetics. Nat. Rev. Genet. 7, 45-54
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 45-54
    • O'Driscoll, M.1    Jeggo, P.A.2
  • 2
    • 0031904003 scopus 로고    scopus 로고
    • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae
    • Kirkpatrick, D. T., Dominska, M., and Petes, T. D. (1998) Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. Genetics 149, 1693-1705
    • (1998) Genetics , vol.149 , pp. 1693-1705
    • Kirkpatrick, D.T.1    Dominska, M.2    Petes, T.D.3
  • 3
    • 0033049472 scopus 로고    scopus 로고
    • Contribution of gene conversion in the evolution of the human β-like globin gene family
    • Papadakis, M. N., and Patrinos, G. P. (1999) Contribution of gene conversion in the evolution of the human β-like globin gene family. Hum. Genet. 104, 117-125
    • (1999) Hum. Genet. , vol.104 , pp. 117-125
    • Papadakis, M.N.1    Patrinos, G.P.2
  • 4
    • 34249945536 scopus 로고    scopus 로고
    • DNA double-strand break repair: From mechanistic understanding to cancer treatment
    • Helleday, T., Lo, J., van Gent, D. C., and Engelward, B. P. (2007) DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair 6, 923-935
    • (2007) DNA Repair , vol.6 , pp. 923-935
    • Helleday, T.1    Lo, J.2    Van Gent, D.C.3    Engelward, B.P.4
  • 5
    • 0020541955 scopus 로고
    • The double-strand-break repair model for recombination
    • Szostak, J. W., Orr-Weaver, T. L., Rothstein, R. J., and Stahl, F. W. (1983) The double-strand-break repair model for recombination. Cell 33, 25-35
    • (1983) Cell , vol.33 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.L.2    Rothstein, R.J.3    Stahl, F.W.4
  • 6
    • 34547194269 scopus 로고    scopus 로고
    • Interchromosomal crossover in human cells is associated with long gene conversion tracts
    • Neuwirth, E. A., Honma, M., and Grosovsky, A. J. (2007) Interchromosomal crossover in human cells is associated with long gene conversion tracts. Mol. Cell. Biol. 27, 5261-5274
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 5261-5274
    • Neuwirth, E.A.1    Honma, M.2    Grosovsky, A.J.3
  • 7
    • 2442690342 scopus 로고    scopus 로고
    • Dynamics of a human interparalog gene conversion hotspot
    • Bosch, E., Hurles, M. E., Navarro, A., and Jobling, M. A. (2004) Dynamics of a human interparalog gene conversion hotspot. Genome Res. 14, 835-844
    • (2004) Genome Res. , vol.14 , pp. 835-844
    • Bosch, E.1    Hurles, M.E.2    Navarro, A.3    Jobling, M.A.4
  • 9
    • 31544454387 scopus 로고    scopus 로고
    • Gene conversion is a frequent mechanism of inactivation of the wild-type allele in cancers from MLH1/MSH2 deletion carriers
    • Zhang, J., Lindroos, A., Ollila, S., Russell, A., Marra, G., Mueller, H., Peltomaki, P., Plasilova, M., and Heinimann, K. (2006) Gene conversion is a frequent mechanism of inactivation of the wild-type allele in cancers from MLH1/MSH2 deletion carriers. Cancer Res. 66, 659-664
    • (2006) Cancer Res. , vol.66 , pp. 659-664
    • Zhang, J.1    Lindroos, A.2    Ollila, S.3    Russell, A.4    Marra, G.5    Mueller, H.6    Peltomaki, P.7    Plasilova, M.8    Heinimann, K.9
  • 11
    • 77649131406 scopus 로고    scopus 로고
    • Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
    • Moynahan, M. E., and Jasin, M. (2010) Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 11, 196-207
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 196-207
    • Moynahan, M.E.1    Jasin, M.2
  • 12
    • 5644277503 scopus 로고    scopus 로고
    • Mismatch repair proteins: Key regulators of genetic recombination
    • Surtees, J. A., Argueso, J. L., and Alani, E. (2004) Mismatch repair proteins: Key regulators of genetic recombination. Cytogenet Genome Res. 107, 146-159
    • (2004) Cytogenet Genome Res. , vol.107 , pp. 146-159
    • Surtees, J.A.1    Argueso, J.L.2    Alani, E.3
  • 13
    • 0032922005 scopus 로고    scopus 로고
    • The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast
    • Chen, W., and Jinks-Robertson, S. (1999) The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast. Genetics 151, 1299-1313
    • (1999) Genetics , vol.151 , pp. 1299-1313
    • Chen, W.1    Jinks-Robertson, S.2
  • 14
    • 0030885649 scopus 로고    scopus 로고
    • Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast
    • Datta, A., Hendrix, M., Lipsitch, M., and Jinks-Robertson, S. (1997) Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast. Proc. Natl. Acad. Sci. U.S.A. 94, 9757-9762
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 9757-9762
    • Datta, A.1    Hendrix, M.2    Lipsitch, M.3    Jinks-Robertson, S.4
  • 15
    • 0034500024 scopus 로고    scopus 로고
    • DNA mismatch repair and genetic instability
    • Harfe, B. D., and Jinks-Robertson, S. (2000) DNA mismatch repair and genetic instability. Annu. Rev. Genet. 34, 359-399
    • (2000) Annu. Rev. Genet. , vol.34 , pp. 359-399
    • Harfe, B.D.1    Jinks-Robertson, S.2
  • 16
    • 0036563287 scopus 로고    scopus 로고
    • Evidence for the lack of mismatch repair-directed antirecombination during mouse meiosis
    • Qin, J., Baker, S., Te Riele, H., Liskay, R. M., and Arnheim, N. (2002) Evidence for the lack of mismatch repair-directed antirecombination during mouse meiosis. J. Hered. 93, 201-205
    • (2002) J. Hered. , vol.93 , pp. 201-205
    • Qin, J.1    Baker, S.2    Te Riele, H.3    Liskay, R.M.4    Arnheim, N.5
  • 18
    • 31644444587 scopus 로고    scopus 로고
    • High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells
    • Wang, Q., Ponomareva, O. N., Lasarev, M., and Turker, M. S. (2006) High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells. Mutat. Res. 594, 189-198
    • (2006) Mutat. Res. , vol.594 , pp. 189-198
    • Wang, Q.1    Ponomareva, O.N.2    Lasarev, M.3    Turker, M.S.4
  • 19
    • 72549108617 scopus 로고    scopus 로고
    • Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells
    • Yan, T., Seo, Y., and Kinsella, T. J. (2009) Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells. Clin. Cancer Res. 15, 6912-6920
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6912-6920
    • Yan, T.1    Seo, Y.2    Kinsella, T.J.3
  • 20
    • 58149145579 scopus 로고    scopus 로고
    • Human MutL complexes monitor homologous recombination independently of mismatch repair
    • Siehler, S. Y., Schrauder, M., Gerischer, U., Cantor, S., Marra, G., and Wiesmüller, L. (2009) Human MutL complexes monitor homologous recombination independently of mismatch repair. DNA Repair 8, 242-252
    • (2009) DNA Repair , vol.8 , pp. 242-252
    • Siehler, S.Y.1    Schrauder, M.2    Gerischer, U.3    Cantor, S.4    Marra, G.5    Wiesmüller, L.6
  • 22
    • 0030779879 scopus 로고    scopus 로고
    • Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells
    • Taghian, D. G., and Nickoloff, J. A. (1997) Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells. Mol. Cell. Biol. 17, 6386-6393
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6386-6393
    • Taghian, D.G.1    Nickoloff, J.A.2
  • 24
    • 19444379003 scopus 로고    scopus 로고
    • hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
    • Vo, A. T., Zhu, F., Wu, X., Yuan, F., Gao, Y., Gu, L., Li, G. M., Lee, T. H., and Her, C. (2005) hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO Rep. 6, 438-444
    • (2005) EMBO Rep. , vol.6 , pp. 438-444
    • Vo, A.T.1    Zhu, F.2    Wu, X.3    Yuan, F.4    Gao, Y.5    Gu, L.6    Li, G.M.7    Lee, T.H.8    Her, C.9
  • 25
    • 0028237305 scopus 로고
    • Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
    • Rouet, P., Smih, F., and Jasin, M. (1994) Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 91, 6064-6068
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 6064-6068
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 26
    • 0031863007 scopus 로고    scopus 로고
    • Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells
    • Donoho, G., Jasin, M., and Berg, P. (1998) Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol. Cell. Biol. 18, 4070-4078
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4070-4078
    • Donoho, G.1    Jasin, M.2    Berg, P.3
  • 27
    • 84872207282 scopus 로고    scopus 로고
    • Deleted in proof
    • Deleted in proof
  • 28
    • 0027269844 scopus 로고
    • Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction
    • Fang, W. H., and Modrich, P. (1993) Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. J. Biol. Chem. 268, 11838-11844
    • (1993) J. Biol. Chem. , vol.268 , pp. 11838-11844
    • Fang, W.H.1    Modrich, P.2
  • 29
    • 0030815268 scopus 로고    scopus 로고
    • DNA replication and postreplication mismatch repair in cell-free extracts from cultured human neuroblastoma and fibroblast cells
    • David, P., Efrati, E., Tocco, G., Krauss, S. W., and Goodman, M. F. (1997) DNA replication and postreplication mismatch repair in cell-free extracts from cultured human neuroblastoma and fibroblast cells. J. Neurosci. 17, 8711-8720
    • (1997) J. Neurosci. , vol.17 , pp. 8711-8720
    • David, P.1    Efrati, E.2    Tocco, G.3    Krauss, S.W.4    Goodman, M.F.5
  • 30
    • 66149115286 scopus 로고    scopus 로고
    • The nucleotide binding dynamics of human MSH2-MSH3 are lesion-dependent
    • Owen, B. A., H. Lang, W., and McMurray, C. T. (2009) The nucleotide binding dynamics of human MSH2-MSH3 are lesion-dependent. Nat. Struct. Mol. Biol. 16, 550-557
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 550-557
    • Owen, B.A.H.1    Lang, W.2    McMurray, C.T.3
  • 31
    • 0027095976 scopus 로고
    • The purification of a human mismatch- binding protein and identification of its associated ATPase and helicase activities
    • Hughes, M. J., and Jiricny, J. (1992) The purification of a human mismatch- binding protein and identification of its associated ATPase and helicase activities. J. Biol. Chem. 267, 23876-23882
    • (1992) J. Biol. Chem. , vol.267 , pp. 23876-23882
    • Hughes, M.J.1    Jiricny, J.2
  • 32
    • 0029659046 scopus 로고    scopus 로고
    • hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
    • Palombo, F., Iaccarino, I., Nakajima, E., Ikejima, M., Shimada, T., and Jiricny, J. (1996) hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 6, 1181-1184
    • (1996) Curr. Biol. , vol.6 , pp. 1181-1184
    • Palombo, F.1    Iaccarino, I.2    Nakajima, E.3    Ikejima, M.4    Shimada, T.5    Jiricny, J.6
  • 33
    • 28844503379 scopus 로고    scopus 로고
    • Human mismatch repair: Reconstitution of a nick-directed bidirectional reaction
    • Constantin, N., Dzantiev, L., Kadyrov, F. A., and Modrich, P. (2005) Human mismatch repair: Reconstitution of a nick-directed bidirectional reaction. J. Biol. Chem. 280, 39752-39761
    • (2005) J. Biol. Chem. , vol.280 , pp. 39752-39761
    • Constantin, N.1    Dzantiev, L.2    Kadyrov, F.A.3    Modrich, P.4
  • 34
    • 33746189409 scopus 로고    scopus 로고
    • Endonucleolytic function of MutLα in human mismatch repair
    • Kadyrov, F. A., Dzantiev, L., Constantin, N., and Modrich, P. (2006) Endonucleolytic function of MutLα in human mismatch repair. Cell 126, 297-308
    • (2006) Cell , vol.126 , pp. 297-308
    • Kadyrov, F.A.1    Dzantiev, L.2    Constantin, N.3    Modrich, P.4
  • 35
    • 81755181064 scopus 로고    scopus 로고
    • Causal link between micro-satellite instability and hMRE11 dysfunction in human cancers
    • Wu, X., Xu, Y., Chai, W., and Her, C. (2011) Causal link between micro-satellite instability and hMRE11 dysfunction in human cancers. Mol. Cancer Res. 9, 1443-1448
    • (2011) Mol. Cancer Res. , vol.9 , pp. 1443-1448
    • Wu, X.1    Xu, Y.2    Chai, W.3    Her, C.4
  • 36
    • 0037019607 scopus 로고    scopus 로고
    • Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1
    • Her, C., Vo, A. T., and Wu, X. (2002) Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1. DNA Repair 1, 719-729
    • (2002) DNA Repair , vol.1 , pp. 719-729
    • Her, C.1    Vo, A.T.2    Wu, X.3
  • 38
    • 0034655991 scopus 로고    scopus 로고
    • BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
    • Wang, Y., Cortez, D., Yazdi, P., Neff, N., Elledge, S. J., and Qin, J. (2000) BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14, 927-939
    • (2000) Genes Dev. , vol.14 , pp. 927-939
    • Wang, Y.1    Cortez, D.2    Yazdi, P.3    Neff, N.4    Elledge, S.J.5    Qin, J.6
  • 40
    • 68249146431 scopus 로고    scopus 로고
    • Role of mammalian Mre11 in classical and alternative nonhomologous end joining
    • Xie, A., Kwok, A., and Scully, R. (2009) Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat. Struct. Mol. Biol. 16, 814-818
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 814-818
    • Xie, A.1    Kwok, A.2    Scully, R.3
  • 42
    • 71049189711 scopus 로고    scopus 로고
    • Exonuclease function of human Mre11 promotes deletional nonhomologous end joining
    • Zhuang, J., Jiang, G., Willers, H., and Xia, F. (2009) Exonuclease function of human Mre11 promotes deletional nonhomologous end joining. J. Biol. Chem. 284, 30565-30573
    • (2009) J. Biol. Chem. , vol.284 , pp. 30565-30573
    • Zhuang, J.1    Jiang, G.2    Willers, H.3    Xia, F.4
  • 43
    • 24144447320 scopus 로고    scopus 로고
    • Reconstitution of 5′-directed human mismatch repair in a purified system
    • Zhang, Y., Yuan, F., Presnell, S. R., Tian, K., Gao, Y., Tomkinson, A. E., Gu, L., and Li, G. M. (2005) Reconstitution of 5′-directed human mismatch repair in a purified system. Cell 122, 693-705
    • (2005) Cell , vol.122 , pp. 693-705
    • Zhang, Y.1    Yuan, F.2    Presnell, S.R.3    Tian, K.4    Gao, Y.5    Tomkinson, A.E.6    Gu, L.7    Li, G.M.8
  • 45
    • 1842685232 scopus 로고    scopus 로고
    • Modulation of error-prone double-strand break repair in mammalian chromosomes by DNA mismatch repair protein Mlh1
    • Bannister, L. A., Waldman, B. C., and Waldman, A. S. (2004) Modulation of error-prone double-strand break repair in mammalian chromosomes by DNA mismatch repair protein Mlh1. DNA Repair 3, 465-474
    • (2004) DNA Repair , vol.3 , pp. 465-474
    • Bannister, L.A.1    Waldman, B.C.2    Waldman, A.S.3
  • 46
    • 0034461607 scopus 로고    scopus 로고
    • Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells
    • Richardson, C., and Jasin, M. (2000) Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol. Cell. Biol. 20, 9068-9075
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 9068-9075
    • Richardson, C.1    Jasin, M.2
  • 47
    • 0029896663 scopus 로고    scopus 로고
    • Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae
    • Saparbaev, M., Prakash, L., and Prakash, S. (1996) Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae. Genetics 142, 727-736
    • (1996) Genetics , vol.142 , pp. 727-736
    • Saparbaev, M.1    Prakash, L.2    Prakash, S.3
  • 48
    • 0030834260 scopus 로고    scopus 로고
    • Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in doublestrand break-induced recombination
    • Sugawara, N., Pâques, F., Colaiácovo, M., and Haber, J. E. (1997) Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in doublestrand break-induced recombination. Proc. Natl. Acad. Sci. U.S.A. 94, 9214-9219
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 9214-9219
    • Sugawara, N.1    Pâques, F.2    Colaiácovo, M.3    Haber, J.E.4
  • 49
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signaling
    • D'Amours, D., and Jackson, S. P. (2002) The Mre11 complex: At the crossroads of DNA repair and checkpoint signaling. Nat. Rev. Mol. Cell Biol. 3, 317-327
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 51
    • 70450237030 scopus 로고    scopus 로고
    • Evidence that nucleosomes inhibit mismatch repair in eukaryotic cells
    • Li, F., Tian, L., Gu, L., and Li, G. M. (2009) Evidence that nucleosomes inhibit mismatch repair in eukaryotic cells. J. Biol. Chem. 284, 33056-33061
    • (2009) J. Biol. Chem. , vol.284 , pp. 33056-33061
    • Li, F.1    Tian, L.2    Gu, L.3    Li, G.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.