Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation

British Journal of Haematology

Volumn 148, Issue 1, 2010, Pages 69-79

  Li, Xiaoqing ^a,b   Liu, Jun ^a,b   Zhou, Rui ^b   Huang, Shi ^c   Huang, Shiang ^a   Chen, Xian Ming ^b  

^a Union Hospital   (China)

^b CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

DNA methylation; Epigenetics; Histone modification; MicroRNA 22; MicroRNAs

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; HISTONE; MICRORNA; TRICHOSTATIN A;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B CELL LEUKEMIA; CANCER CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MIR22 GENE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; RNA GENE; UPREGULATION;

AZACITIDINE; CPG ISLANDS; DNA METHYLATION; DNA, NEOPLASM; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, NEOPLASM; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYDROXAMIC ACIDS; MICRORNAS; POLYMERASE CHAIN REACTION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC; TUMOR CELLS, CULTURED;

EID: 72249107533     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07920.x     Document Type: Article

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