메뉴 건너뛰기




Volumn 10, Issue 4, 2012, Pages 382-392

The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix

Author keywords

[No Author keywords available]

Indexed keywords

2,3 BIS (2 METHOXY 4 NITRO 5 SULFOPHENYL) 2H TETRAZOLIUM 5 CARBOXANILIDE; CARBOXIN; COLLAGEN; MATRIGEL; UNCLASSIFIED DRUG;

EID: 84865460836     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2011.391     Document Type: Article
Times cited : (77)

References (59)
  • 1
    • 56449122304 scopus 로고    scopus 로고
    • A high density assay format for the detection of novel cytotoxic agents in large chemical libraries
    • Shum D, Radu C, Kim E, et al.: A high density assay format for the detection of novel cytotoxic agents in large chemical libraries. J Enzyme Inhib Med Chem 2008;23:931-945.
    • (2008) J Enzyme Inhib Med Chem , vol.23 , pp. 931-945
    • Shum, D.1    Radu, C.2    Kim, E.3
  • 2
    • 77649203114 scopus 로고    scopus 로고
    • Microplate spectrophotometry for high-throughput screening of cytotoxic molecules
    • Tomelleri C, Dalla Pellegrina C, Chignola R: Microplate spectrophotometry for high-throughput screening of cytotoxic molecules. Cell Prolif 2010;43:130-138.
    • (2010) Cell Prolif , vol.43 , pp. 130-138
    • Tomelleri, C.1    Dalla Pellegrina, C.2    Chignola, R.3
  • 3
    • 0035823098 scopus 로고    scopus 로고
    • Cytotoxicity tests for high-throughput drug discovery
    • DOI 10.1016/S0958-1669(00)00177-4
    • Slater K: Cytotoxicity tests for high-throughput drug discovery. Curr Opin Biotechnol 2001;12:70-74. (Pubitemid 32843147)
    • (2001) Current Opinion in Biotechnology , vol.12 , Issue.1 , pp. 70-74
    • Slater, K.1
  • 4
    • 33748872333 scopus 로고    scopus 로고
    • High throughput screening in drug discovery
    • Carnero A: High throughput screening in drug discovery. Clin Transl Oncol 2006;8:482-490.
    • (2006) Clin Transl Oncol , vol.8 , pp. 482-490
    • Carnero, A.1
  • 5
    • 58149178486 scopus 로고    scopus 로고
    • 3D cell culture opens new dimensions in cellbased assays
    • Justice BA, Badr NA, Felder RA: 3D cell culture opens new dimensions in cellbased assays. Drug Discov Today 2009;14:102-107.
    • (2009) Drug Discov Today , vol.14 , pp. 102-107
    • Justice, B.A.1    Badr, N.A.2    Felder, R.A.3
  • 6
    • 79953670987 scopus 로고    scopus 로고
    • Biophysical regulation of tumor cell invasion: Moving beyond matrix stiffness
    • Pathak A, Kumar S: Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness. Integr Biol (Camb) 2011;3:267-278.
    • (2011) Integr Biol (Camb) , vol.3 , pp. 267-278
    • Pathak, A.1    Kumar, S.2
  • 8
    • 0042358985 scopus 로고    scopus 로고
    • Biology's new dimension
    • DOI 10.1038/424870a
    • Abbott A: Cell culture: biology's new dimension. Nature 2003;424:870-872. (Pubitemid 37051657)
    • (2003) Nature , vol.424 , Issue.6951 , pp. 870-872
    • Abbott, A.1
  • 9
    • 33748685968 scopus 로고    scopus 로고
    • ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through β1 integrin-dependent activation of PI3-kinase
    • DOI 10.1038/sj.cdd.4401849, PII 4401849
    • Hodkinson PS, Elliott T, Wong WS, et al.: ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrindependent activation of PI3-kinase. Cell Death Differ 2006;13:1776-1788. (Pubitemid 44390864)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.10 , pp. 1776-1788
    • Hodkinson, P.S.1    Elliott, T.2    Wong, W.S.3    Rintoul, R.C.4    Mackinnon, A.C.5    Haslett, C.6    Sethi, T.7
  • 10
    • 34547931078 scopus 로고    scopus 로고
    • Modeling Tissue Morphogenesis and Cancer in 3D
    • DOI 10.1016/j.cell.2007.08.006, PII S0092867407010288
    • Yamada KM, Cukierman E: Modeling tissue morphogenesis and cancer in 3D. Cell 2007;130:601-610. (Pubitemid 47268064)
    • (2007) Cell , vol.130 , Issue.4 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 11
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • DOI 10.1038/nmeth1015, PII NMETH1015
    • Lee GY, Kenny PA, Lee EH, Bissell MJ: Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 2007;4:359-365. (Pubitemid 46766981)
    • (2007) Nature Methods , vol.4 , Issue.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 12
    • 4544382532 scopus 로고    scopus 로고
    • Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen
    • DOI 10.1016/j.biomaterials.2004.04.012, PII S0142961204003539
    • Dhiman HK, Ray AR, Panda AK: Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen. Biomaterials 2005;26:979-986. (Pubitemid 39213976)
    • (2005) Biomaterials , vol.26 , Issue.9 , pp. 979-986
    • Dhiman, H.K.1    Ray, A.R.2    Panda, A.K.3
  • 13
    • 79959887793 scopus 로고    scopus 로고
    • The use of nanoimprinted scaffolds as 3D culture models to facilitate spontaneous tumor cell migration and wellregulated spheroid formation
    • Yoshii Y, Waki A, Yoshida K, et al.: The use of nanoimprinted scaffolds as 3D culture models to facilitate spontaneous tumor cell migration and wellregulated spheroid formation. Biomaterials 2011;32:6052-6058.
    • (2011) Biomaterials , vol.32 , pp. 6052-6058
    • Yoshii, Y.1    Waki, A.2    Yoshida, K.3
  • 14
    • 41549140437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells
    • Shen YH, Shoichet MS, Radisic M: Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells. Acta Biomater 2008;4:477-489.
    • (2008) Acta Biomater , vol.4 , pp. 477-489
    • Shen, Y.H.1    Shoichet, M.S.2    Radisic, M.3
  • 15
    • 77955968267 scopus 로고    scopus 로고
    • Developments in three-dimensional cell culture technology aimed at improving the accuracy of in vitro analyses
    • Maltman DJ, Przyborski SA: Developments in three-dimensional cell culture technology aimed at improving the accuracy of in vitro analyses. Biochem Soc Trans 2010;38:1072-1075.
    • (2010) Biochem Soc Trans , vol.38 , pp. 1072-1075
    • Maltman, D.J.1    Przyborski, S.A.2
  • 16
    • 67650169752 scopus 로고    scopus 로고
    • Hydrogels as extracellular matrix mimics for 3D cell culture
    • Tibbitt MW, Anseth KS: Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng 2009;103:655-663.
    • (2009) Biotechnol Bioeng , vol.103 , pp. 655-663
    • Tibbitt, M.W.1    Anseth, K.S.2
  • 17
    • 38349143408 scopus 로고    scopus 로고
    • Evaluating drug efficacy and toxicology in three dimensions: Using synthetic extracellular matrices in drug discovery
    • Prestwich GD: Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery. Acc Chem Res 2008;41:139-148.
    • (2008) Acc Chem Res , vol.41 , pp. 139-148
    • Prestwich, G.D.1
  • 18
    • 77956611459 scopus 로고    scopus 로고
    • Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors
    • Cukierman E, Bassi DE: Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors. Semin Cancer Biol 2010;20:139-145.
    • (2010) Semin Cancer Biol , vol.20 , pp. 139-145
    • Cukierman, E.1    Bassi, D.E.2
  • 19
    • 70449133451 scopus 로고    scopus 로고
    • Collagen-based cell migration models in vitro and in vivo
    • Wolf K, Alexander S, Schacht V, et al.: Collagen-based cell migration models in vitro and in vivo. Semin Cell Dev Biol 2009;20:931-941.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 931-941
    • Wolf, K.1    Alexander, S.2    Schacht, V.3
  • 20
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63. (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 22
    • 0035427561 scopus 로고    scopus 로고
    • Sensitive determination of cell number using the CyQUANT® cell proliferation assay
    • DOI 10.1016/S0022-1759(01)00404-5, PII S0022175901004045
    • Jones LJ, Gray M, Yue ST, Haugland RP, Singer VL: Sensitive determination of cell number using the CyQUANT cell proliferation assay. J Immunol Methods 2001;254:85-98. (Pubitemid 32530750)
    • (2001) Journal of Immunological Methods , vol.254 , Issue.1-2 , pp. 85-98
    • Jones, L.J.1    Gray, M.2    Yue, S.T.3    Haugland, R.P.4    Singer, V.L.5
  • 23
    • 57049161490 scopus 로고    scopus 로고
    • High-throughput screening platform for anticancer therapeutic drug cytotoxicity
    • Sekhon BK, Roubin RH, Tan A, Chan WK, Sze DM: High-throughput screening platform for anticancer therapeutic drug cytotoxicity. Assay Drug Dev Technol 2008;6:711-721.
    • (2008) Assay Drug Dev Technol , vol.6 , pp. 711-721
    • Sekhon, B.K.1    Roubin, R.H.2    Tan, A.3    Chan, W.K.4    Sze, D.M.5
  • 24
    • 77953953888 scopus 로고    scopus 로고
    • Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research
    • Quent VM, Loessner D, Friis T, Reichert JC, Hutmacher DW: Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research. J Cell Mol Med 2010;14:1003-1013.
    • (2010) J Cell Mol Med , vol.14 , pp. 1003-1013
    • Quent, V.M.1    Loessner, D.2    Friis, T.3    Reichert, J.C.4    Hutmacher, D.W.5
  • 25
    • 0031852098 scopus 로고    scopus 로고
    • A novel one-step, highly sensitive fluorometric assay to evaluate cell- mediated cytotoxicity
    • DOI 10.1016/S0022-1759(98)00028-3, PII S0022175998000283
    • Nociari MM, Shalev A, Benias P, Russo C: A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity. J Immunol Methods 1998;213:157-167. (Pubitemid 28332808)
    • (1998) Journal of Immunological Methods , vol.213 , Issue.2 , pp. 157-167
    • Nociari, M.M.1    Shalev, A.2    Benias, P.3    Russo, C.4
  • 26
    • 0023792919 scopus 로고
    • Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
    • Scudiero DA, Shoemaker RH, Paull KD, et al.: Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 1988;48:4827-4833.
    • (1988) Cancer Res , vol.48 , pp. 4827-4833
    • Scudiero, D.A.1    Shoemaker, R.H.2    Paull, K.D.3
  • 27
    • 84858333989 scopus 로고    scopus 로고
    • Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin
    • Huertas D, Soler M, Moreto J, et al.: Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene 2012;31:1408-1418.
    • (2012) Oncogene , vol.31 , pp. 1408-1418
    • Huertas, D.1    Soler, M.2    Moreto, J.3
  • 28
    • 70449360366 scopus 로고    scopus 로고
    • Cisplatin cytotoxicity is increased by mifepristone in cervical carcinoma: An in vitro and in vivo study
    • Jurado R, Lopez-Flores A, Alvarez A, Garcia-Lopez P: Cisplatin cytotoxicity is increased by mifepristone in cervical carcinoma: an in vitro and in vivo study. Oncol Rep 2009;22:1237-1245.
    • (2009) Oncol Rep , vol.22 , pp. 1237-1245
    • Jurado, R.1    Lopez-Flores, A.2    Alvarez, A.3    Garcia-Lopez, P.4
  • 29
    • 0036348389 scopus 로고    scopus 로고
    • Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines
    • Mad'arova J, Lukesova M, Hlobilkova A, et al.: Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines. Mol Pathol 2002;55:227-234.
    • (2002) Mol Pathol , vol.55 , pp. 227-234
    • Mad'arova, J.1    Lukesova, M.2    Hlobilkova, A.3
  • 30
    • 0032699619 scopus 로고    scopus 로고
    • Effect of cell plating density and extracellular matrix protein on cell growth of epithelial rests of Malassez in vitro
    • Nishimura M, Abiko Y, Mitamura J, Kaku T: Effect of cell plating density and extracellular matrix protein on cell growth of epithelial rests of Malassez in vitro. Med Electron Microsc 1999;32:127-132.
    • (1999) Med Electron Microsc , vol.32 , pp. 127-132
    • Nishimura, M.1    Abiko, Y.2    Mitamura, J.3    Kaku, T.4
  • 31
    • 61449561797 scopus 로고    scopus 로고
    • Effect of interleukins response to ECM-induced acquisition of drug resistance in MCF-7 cells
    • Ohbayashi M, Yasuda M, Kawakami I, Kohyama N, Kobayashi Y, Yamamoto T: Effect of interleukins response to ECM-induced acquisition of drug resistance in MCF-7 cells. Exp Oncol 2008;30:276-282.
    • (2008) Exp Oncol , vol.30 , pp. 276-282
    • Ohbayashi, M.1    Yasuda, M.2    Kawakami, I.3    Kohyama, N.4    Kobayashi, Y.5    Yamamoto, T.6
  • 32
    • 0031808060 scopus 로고    scopus 로고
    • Reduced viability of human vascular endothelial cells cultured on matrigel
    • DOI 10.1002/(SICI)1097-4652(199807)176:1<92::AID-JCP11>3.0.CO;2-Q
    • Ranta V, Mikkola T, Ylikorkala O, Viinikka L, Orpana A: Reduced viability of human vascular endothelial cells cultured on Matrigel. J Cell Physiol 1998;176:92-98. (Pubitemid 28277199)
    • (1998) Journal of Cellular Physiology , vol.176 , Issue.1 , pp. 92-98
    • Ranta, V.1    Mikkola, T.2    Ylikorkala, O.3    Viinikka, L.4    Orpana, A.5
  • 33
    • 78650173842 scopus 로고    scopus 로고
    • Three-dimensional culture of rat BMMSCs in a porous chitosan-gelatin scaffold: A promising association for bone tissue engineering in oral reconstruction
    • Miranda SC, Silva GA, Hell RC, Martins MD, Alves JB, Goes AM: Three-dimensional culture of rat BMMSCs in a porous chitosan-gelatin scaffold: A promising association for bone tissue engineering in oral reconstruction. Arch Oral Biol 2011;56:1-15.
    • (2011) Arch Oral Biol , vol.56 , pp. 1-15
    • Miranda, S.C.1    Silva, G.A.2    Hell, R.C.3    Martins, M.D.4    Alves, J.B.5    Goes, A.M.6
  • 34
    • 77952946124 scopus 로고    scopus 로고
    • In vitro evaluation of the compatibility of a novel collagen-heparan sulfate biological scaffold with olfactory ensheathing cells
    • Tang ZP, Liu N, Li ZW, et al.: In vitro evaluation of the compatibility of a novel collagen-heparan sulfate biological scaffold with olfactory ensheathing cells. Chin Med J (Engl) 2010;123:1299-1304.
    • (2010) Chin Med J (Engl) , vol.123 , pp. 1299-1304
    • Tang, Z.P.1    Liu, N.2    Li, Z.W.3
  • 35
    • 78650283515 scopus 로고    scopus 로고
    • Defining conditions for covalent immobilization of angiogenic growth factors onto scaffolds for tissue engineering
    • Chiu LL, Weisel RD, Li RK, Radisic M: Defining conditions for covalent immobilization of angiogenic growth factors onto scaffolds for tissue engineering. J Tissue Eng Regen Med 2011;5:69-84.
    • (2011) J Tissue Eng Regen Med , vol.5 , pp. 69-84
    • Chiu, L.L.1    Weisel, R.D.2    Li, R.K.3    Radisic, M.4
  • 36
    • 77954890424 scopus 로고    scopus 로고
    • QSG-7701 human hepatocytes form polarized acini in three-dimensional culture
    • Zhang F, Xu R, Zhao MJ: QSG-7701 human hepatocytes form polarized acini in three-dimensional culture. J Cell Biochem 2010;110:1175-1186.
    • (2010) J Cell Biochem , vol.110 , pp. 1175-1186
    • Zhang, F.1    Xu, R.2    Zhao, M.J.3
  • 37
    • 84860523085 scopus 로고    scopus 로고
    • Collagen three-dimensional hydrogel matrix carrying basic fibroblast growth factor for the cultivation of mesenchymal stem cells and osteogenic differentiation
    • Oh SA, Lee HY, Lee JH, et al.: Collagen three-dimensional hydrogel matrix carrying basic fibroblast growth factor for the cultivation of mesenchymal stem cells and osteogenic differentiation. Tissue Eng Part A 2012;18:1087-1100.
    • (2012) Tissue Eng Part A , vol.18 , pp. 1087-1100
    • Oh, S.A.1    Lee, H.Y.2    Lee, J.H.3
  • 38
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • DOI 10.1177/108705719900400206
    • Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67-73. (Pubitemid 29278954)
    • (1999) Journal of Biomolecular Screening , vol.4 , Issue.2 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.Y.2    Oldenburg, K.R.3
  • 39
    • 79951979271 scopus 로고    scopus 로고
    • A quantitative, facile, and highthroughput image-based cell migration method is a robust alternative to the scratch assay
    • Gough W, Hulkower KI, Lynch R, et al.: A quantitative, facile, and highthroughput image-based cell migration method is a robust alternative to the scratch assay. J Biomol Screen 2011;16:155-163.
    • (2011) J Biomol Screen , vol.16 , pp. 155-163
    • Gough, W.1    Hulkower, K.I.2    Lynch, R.3
  • 40
    • 70350198030 scopus 로고    scopus 로고
    • Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells
    • Nizamutdinova IT, Kim YM, Chung JI, et al.: Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells. Food Chem Toxicol 2009;47:2806-2812.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2806-2812
    • Nizamutdinova, I.T.1    Kim, Y.M.2    Chung, J.I.3
  • 42
    • 77952956786 scopus 로고    scopus 로고
    • P53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma
    • Lim SO, Kim H, Jung G: p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma. FEBS Lett 2010;584:2231-2236.
    • (2010) FEBS Lett , vol.584 , pp. 2231-2236
    • Lim, S.O.1    Kim, H.2    Jung, G.3
  • 43
    • 78650676828 scopus 로고    scopus 로고
    • Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells
    • Attoub S, Hassan AH, Vanhoecke B, et al.: Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells. Eur J Pharmacol 2011;651:18-25.
    • (2011) Eur J Pharmacol , vol.651 , pp. 18-25
    • Attoub, S.1    Hassan, A.H.2    Vanhoecke, B.3
  • 44
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three- dimensional culture and in vivo by integrin blocking antibodies
    • DOI 10.1083/jcb.137.1.231
    • Weaver VM, Petersen OW, Wang F, et al.: Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997;137:231-245. (Pubitemid 27167310)
    • (1997) Journal of Cell Biology , vol.137 , Issue.1 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6    Bissell, M.J.7
  • 45
    • 79952111440 scopus 로고    scopus 로고
    • Scaffolds are active" regulators of signaling modules
    • Alexa A, Varga J, Remenyi A: Scaffolds are active" regulators of signaling modules. FEBS J 2010;277:4376-4382.
    • (2010) FEBS J , vol.277 , pp. 4376-4382
    • Alexa, A.1    Varga, J.2    Remenyi, A.3
  • 46
    • 77949752828 scopus 로고    scopus 로고
    • Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells
    • Chen XD: Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells. Birth Defects Res C Embryo Today 2010;90:45-54.
    • (2010) Birth Defects Res C Embryo Today , vol.90 , pp. 45-54
    • Chen, X.D.1
  • 47
    • 33750552711 scopus 로고    scopus 로고
    • Growth of mesenchymal stem cells on electrospun type I collagen nanofibers
    • DOI 10.1634/stemcells.2006-0253
    • Shih YR, Chen CN, Tsai SW, Wang YJ, Lee OK: Growth of mesenchymal stem cells on electrospun type I collagen nanofibers. Stem Cells 2006;24:2391-2397. (Pubitemid 44674298)
    • (2006) Stem Cells , vol.24 , Issue.11 , pp. 2391-2397
    • Shih, Y.-R.V.1    Chen, C.-N.2    Tsai, S.-W.3    Yng, J.W.4    Lee, O.K.5
  • 48
    • 0015962412 scopus 로고
    • Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate
    • Santi DV, McHenry CS, Sommer H: Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry 1974;13:471-481.
    • (1974) Biochemistry , vol.13 , pp. 471-481
    • Santi, D.V.1    McHenry, C.S.2    Sommer, H.3
  • 49
    • 0030739913 scopus 로고    scopus 로고
    • An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug
    • DOI 10.1016/S0006-2952(97)00040-3, PII S0006295297000403
    • Ghoshal K, Jacob ST: An alternative molecular mechanism of action of 5fluorouracil, a potent anticancer drug. Biochem Pharmacol 1997;53:1569-1575. (Pubitemid 27356085)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.11 , pp. 1569-1575
    • Ghoshal, K.1    Jacob, S.T.2
  • 50
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: A multiscale tuning model
    • Friedl P, Wolf K: Plasticity of cell migration: a multiscale tuning model. J Cell Biol 2009;188:11-19.
    • (2009) J Cell Biol , vol.188 , pp. 11-19
    • Friedl, P.1    Wolf, K.2
  • 54
    • 33847073342 scopus 로고    scopus 로고
    • DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma
    • DOI 10.1016/j.bbrc.2007.01.121, PII S0006291X07001581
    • Kim TY, Lee JW, Kim HP, Jong HS, Jung M, Bang YJ: DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma. Biochem Biophys Res Commun 2007;355:72-77. (Pubitemid 46273368)
    • (2007) Biochemical and Biophysical Research Communications , vol.355 , Issue.1 , pp. 72-77
    • Kim, T.Y.1    Lee, J.W.2    Kim, H.-P.3    Jong, H.-S.4    Kim, T.-Y.5    Jung, M.6    Bang, Y.-J.7
  • 55
    • 83055187108 scopus 로고    scopus 로고
    • Rho kinase proteins-pleiotropic modulators of cell survival and apoptosis
    • Street CA, Bryan BA: Rho kinase proteins-pleiotropic modulators of cell survival and apoptosis. Anticancer Res 2011;31:3645-3657.
    • (2011) Anticancer Res , vol.31 , pp. 3645-3657
    • Street, C.A.1    Bryan, B.A.2
  • 56
    • 61449123217 scopus 로고    scopus 로고
    • Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation
    • Zohrabian VM, Forzani B, Chau Z, Murali R, Jhanwar-Uniyal M: Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation. Anticancer Res 2009;29:119-123.
    • (2009) Anticancer Res , vol.29 , pp. 119-123
    • Zohrabian, V.M.1    Forzani, B.2    Chau, Z.3    Murali, R.4    Jhanwar-Uniyal, M.5
  • 57
    • 79953148385 scopus 로고    scopus 로고
    • Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
    • Provenzano PP, Keely PJ: Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J Cell Sci 2011;124(Pt 8):1195-1205.
    • (2011) J Cell Sci , vol.124 , Issue.8 PART , pp. 1195-1205
    • Provenzano, P.P.1    Keely, P.J.2
  • 58
    • 79952129858 scopus 로고    scopus 로고
    • Direct comparisons of the morphology, migration, cell adhesions, and actin cytoskeleton of fibroblasts in four different three-dimensional extracellular matrices
    • Hakkinen KM, Harunaga JS, Doyle AD, Yamada KM: Direct comparisons of the morphology, migration, cell adhesions, and actin cytoskeleton of fibroblasts in four different three-dimensional extracellular matrices. Tissue Eng Part A 2011;17:713-724.
    • (2011) Tissue Eng Part A , vol.17 , pp. 713-724
    • Hakkinen, K.M.1    Harunaga, J.S.2    Doyle, A.D.3    Yamada, K.M.4
  • 59
    • 77955795393 scopus 로고    scopus 로고
    • More than just bare scaffolds: Towards multicomponent and decorated fibrous biomaterials
    • Woolfson DN, Mahmoud ZN: More than just bare scaffolds: towards multicomponent and decorated fibrous biomaterials. Chem Soc Rev 2010;39:3464-3479.
    • (2010) Chem Soc Rev , vol.39 , pp. 3464-3479
    • Woolfson, D.N.1    Mahmoud, Z.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.