A quantitative, facile, and high-throughput image-based cell migration method is a robust alternative to the scratch assay

Journal of Biomolecular Screening

Volumn 16, Issue 2, 2011, Pages 155-163

  Gough, Wendy ^a   Hulkower, Keren I ^b   Lynch, Renee ^a   McGlynn, Patrick ^a   Uhlik, Mark ^a   Yan, Lei ^a   Lee, Jonathan A ^a  

^a ELI LILLY AND COMPANY   (United States)

^b Platypus Technologies LLC   (United States)

Author keywords

cell migration; cellular imaging; dasatinib; high content imaging; high throughput screening; multiplexed assay; phenotypic assay; phenotypic mechanism of action; scratch assay

Indexed keywords

DASATINIB;

ARTICLE; CELL ASSAY; CELL DAMAGE; CELL MIGRATION; COLONY FORMING CELL; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMAGE CYTOMETRY; MOLECULAR IMAGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCRATCH ASSAY; SIGNAL NOISE RATIO; STEM CELL; STRUCTURE ACTIVITY RELATION;

CELL MIGRATION ASSAYS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PROTEIN KINASE INHIBITORS; PYRIMIDINES; THIAZOLES;

EID: 79951979271     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110393340     Document Type: Article

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