메뉴 건너뛰기




Volumn 263, Issue 3, 2012, Pages 338-344

Maternal low-dose estradiol-17β exposure during pregnancy impairs postnatal progeny weight development and body composition

Author keywords

Birth weight; Childhood disease; Endocrine disruptors; Epigenetics; Estradiol 17 ; Fetal basis of adult disease; Obesity

Indexed keywords

ESTRADIOL; TESTOSTERONE;

EID: 84865430575     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.07.006     Document Type: Article
Times cited : (17)

References (61)
  • 1
    • 0026635508 scopus 로고
    • Cellular and molecular aspects of adipose tissue development
    • Ailhaud G., Grimaldi P., Negrel R. Cellular and molecular aspects of adipose tissue development. Annu. Rev. Nutr. 1992, 12:207-233.
    • (1992) Annu. Rev. Nutr. , vol.12 , pp. 207-233
    • Ailhaud, G.1    Grimaldi, P.2    Negrel, R.3
  • 2
    • 0842313074 scopus 로고    scopus 로고
    • Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells
    • Akingbemi B.T., Sottas C.M., Koulova A.I., Klinefelter G.R., Hardy M.P. Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology 2004, 145:592-603.
    • (2004) Endocrinology , vol.145 , pp. 592-603
    • Akingbemi, B.T.1    Sottas, C.M.2    Koulova, A.I.3    Klinefelter, G.R.4    Hardy, M.P.5
  • 4
    • 0023082013 scopus 로고
    • Changes in the genital tract of female swine after feeding with practice-relevant amounts of zearalenone
    • Bauer J., Heinritzi K., Gareis M., Gedek B. Changes in the genital tract of female swine after feeding with practice-relevant amounts of zearalenone. Tierarztl. Prax. 1987, 15:33-36.
    • (1987) Tierarztl. Prax. , vol.15 , pp. 33-36
    • Bauer, J.1    Heinritzi, K.2    Gareis, M.3    Gedek, B.4
  • 5
    • 0031240934 scopus 로고    scopus 로고
    • Hormonal control of regional fat distribution
    • Bjorntorp P. Hormonal control of regional fat distribution. Hum. Reprod. 1997, 12(Suppl. 1):21-25.
    • (1997) Hum. Reprod. , vol.12 , Issue.SUPPL. 1 , pp. 21-25
    • Bjorntorp, P.1
  • 6
    • 58149212804 scopus 로고
    • Inverse relationship between testicular proliferation and apoptosis in mammalian seasonal breeders
    • Blottner S., Hingst O., Meyer H.H. Inverse relationship between testicular proliferation and apoptosis in mammalian seasonal breeders. Theriogenology 1995, 44:321-328.
    • (1995) Theriogenology , vol.44 , pp. 321-328
    • Blottner, S.1    Hingst, O.2    Meyer, H.H.3
  • 7
    • 0035545490 scopus 로고    scopus 로고
    • Assessment of meat fat content using dual energy X-ray absorption
    • Brienne J.P., Denoyelle C., Baussart H., Daudin J.D. Assessment of meat fat content using dual energy X-ray absorption. Meat Sci. 2001, 57:235-244.
    • (2001) Meat Sci. , vol.57 , pp. 235-244
    • Brienne, J.P.1    Denoyelle, C.2    Baussart, H.3    Daudin, J.D.4
  • 8
    • 0031840552 scopus 로고    scopus 로고
    • Autoregulation of estrogen and androgen receptor mRNAs and downregulation of androgen receptor mRNA by estrogen in primary cultures of lizard testis cells
    • Cardone A., Angelini F., Varriale B. Autoregulation of estrogen and androgen receptor mRNAs and downregulation of androgen receptor mRNA by estrogen in primary cultures of lizard testis cells. Gen. Comp. Endocrinol. 1998, 110:227-236.
    • (1998) Gen. Comp. Endocrinol. , vol.110 , pp. 227-236
    • Cardone, A.1    Angelini, F.2    Varriale, B.3
  • 11
    • 33845304731 scopus 로고    scopus 로고
    • Rise of testosterone, nortestosterone, and 17beta-estradiol concentrations in peripheral blood plasma of pigs after sublingual application in vivo
    • Claus R., Haussler S., Lacorn M. Rise of testosterone, nortestosterone, and 17beta-estradiol concentrations in peripheral blood plasma of pigs after sublingual application in vivo. Food Chem. Toxicol. 2007, 45:225-228.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 225-228
    • Claus, R.1    Haussler, S.2    Lacorn, M.3
  • 12
    • 1942504144 scopus 로고    scopus 로고
    • Are all estrogens the same?
    • Coelingh Bennink H.J. Are all estrogens the same?. Maturitas 2004, 47:269-275.
    • (2004) Maturitas , vol.47 , pp. 269-275
    • Coelingh Bennink, H.J.1
  • 13
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn T., vom Saal F.S., Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 1993, 101:378-384.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 378-384
    • Colborn, T.1    vom Saal, F.S.2    Soto, A.M.3
  • 14
    • 0034219912 scopus 로고    scopus 로고
    • Detection of anabolic residues in misplaced implantation sites in cattle
    • Daxenberger A., Lange I.G., Meyer K., Meyer H.H. Detection of anabolic residues in misplaced implantation sites in cattle. J. AOAC Int. 2000, 83:809-819.
    • (2000) J. AOAC Int. , vol.83 , pp. 809-819
    • Daxenberger, A.1    Lange, I.G.2    Meyer, K.3    Meyer, H.H.4
  • 15
    • 46349106991 scopus 로고    scopus 로고
    • The effects of estrogen therapy and estrogen combined with different androgenic progestins on carbohydrate and lipid metabolism in overweight-obese younger postmenopausal women
    • Demir B., Ozturkoglu E., Solaroglu A., Baskan B., Kandemir O., Karabulut E., Haberal A. The effects of estrogen therapy and estrogen combined with different androgenic progestins on carbohydrate and lipid metabolism in overweight-obese younger postmenopausal women. Gynecol. Endocrinol. 2008, 24:347-353.
    • (2008) Gynecol. Endocrinol. , vol.24 , pp. 347-353
    • Demir, B.1    Ozturkoglu, E.2    Solaroglu, A.3    Baskan, B.4    Kandemir, O.5    Karabulut, E.6    Haberal, A.7
  • 16
    • 0034465232 scopus 로고    scopus 로고
    • Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor gamma2
    • Dieudonne M.N., Pecquery R., Leneveu M.C., Giudicelli Y. Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor gamma2. Endocrinology 2000, 141:649-656.
    • (2000) Endocrinology , vol.141 , pp. 649-656
    • Dieudonne, M.N.1    Pecquery, R.2    Leneveu, M.C.3    Giudicelli, Y.4
  • 17
    • 34547942682 scopus 로고    scopus 로고
    • Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice
    • Gioiosa L., Fissore E., Ghirardelli G., Parmigiani S., Palanza P. Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice. Horm. Behav. 2007, 52:307-316.
    • (2007) Horm. Behav. , vol.52 , pp. 307-316
    • Gioiosa, L.1    Fissore, E.2    Ghirardelli, G.3    Parmigiani, S.4    Palanza, P.5
  • 18
    • 4544366928 scopus 로고    scopus 로고
    • Living with the past: evolution, development, and patterns of disease
    • Gluckman P.D., Hanson M.A. Living with the past: evolution, development, and patterns of disease. Science 2004, 305:1733-1736.
    • (2004) Science , vol.305 , pp. 1733-1736
    • Gluckman, P.D.1    Hanson, M.A.2
  • 19
    • 34548749230 scopus 로고    scopus 로고
    • Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis
    • Grun F., Blumberg B. Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis. Rev. Endocr. Metab. Disord. 2007, 8:161-171.
    • (2007) Rev. Endocr. Metab. Disord. , vol.8 , pp. 161-171
    • Grun, F.1    Blumberg, B.2
  • 20
    • 33847378868 scopus 로고    scopus 로고
    • Changes of testicular aromatase expression during fetal development in male pigs (Sus scrofa)
    • Haeussler S., Wagner A., Welter H., Claus R. Changes of testicular aromatase expression during fetal development in male pigs (Sus scrofa). Reproduction 2007, 133:323-330.
    • (2007) Reproduction , vol.133 , pp. 323-330
    • Haeussler, S.1    Wagner, A.2    Welter, H.3    Claus, R.4
  • 21
    • 67349125425 scopus 로고    scopus 로고
    • Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity
    • Heindel J.J., vom Saal F.S. Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity. Mol. Cell. Endocrinol. 2009, 304:90-96.
    • (2009) Mol. Cell. Endocrinol. , vol.304 , pp. 90-96
    • Heindel, J.J.1    vom Saal, F.S.2
  • 22
    • 33745246032 scopus 로고    scopus 로고
    • Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4
    • Ho S.M., Tang W.Y., Belmonte de Frausto J., Prins G.S. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Res. 2006, 66:5624-5632.
    • (2006) Cancer Res. , vol.66 , pp. 5624-5632
    • Ho, S.M.1    Tang, W.Y.2    Belmonte de Frausto, J.3    Prins, G.S.4
  • 23
    • 79952808057 scopus 로고    scopus 로고
    • Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity
    • Janesick A., Blumberg B. Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity. Birth Defects Res. C Embryo Today 2011, 93:34-50.
    • (2011) Birth Defects Res. C Embryo Today , vol.93 , pp. 34-50
    • Janesick, A.1    Blumberg, B.2
  • 25
    • 77249160182 scopus 로고    scopus 로고
    • Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes
    • Kirchner S., Kieu T., Chow C., Casey S., Blumberg B. Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol. Endocrinol. 2010, 24:526-539.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 526-539
    • Kirchner, S.1    Kieu, T.2    Chow, C.3    Casey, S.4    Blumberg, B.5
  • 26
    • 40949126212 scopus 로고    scopus 로고
    • Introduction: endocrine disruptors-exposure assessment, novel end points, and low-dose and mixture effects
    • Kortenkamp A. Introduction: endocrine disruptors-exposure assessment, novel end points, and low-dose and mixture effects. Environ. Health Perspect. 2007, 115(Suppl. 1):7.
    • (2007) Environ. Health Perspect. , vol.115 , Issue.SUPPL. 1 , pp. 7
    • Kortenkamp, A.1
  • 27
    • 40349094571 scopus 로고    scopus 로고
    • Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology
    • Kortenkamp A. Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology. Int. J. Androl. 2008, 31:233-240.
    • (2008) Int. J. Androl. , vol.31 , pp. 233-240
    • Kortenkamp, A.1
  • 28
    • 0027222826 scopus 로고
    • Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving
    • Krishnan A.V., Stathis P., Permuth S.F., Tokes L., Feldman D. Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 1993, 132:2279-2286.
    • (1993) Endocrinology , vol.132 , pp. 2279-2286
    • Krishnan, A.V.1    Stathis, P.2    Permuth, S.F.3    Tokes, L.4    Feldman, D.5
  • 29
    • 0037357403 scopus 로고    scopus 로고
    • Estimation of Canadian and European lean yields and composition of pig carcasses by dual-energy X-ray absorptiometry
    • Marcoux M., Bernier J.F., Pomar C. Estimation of Canadian and European lean yields and composition of pig carcasses by dual-energy X-ray absorptiometry. Meat Sci. 2003, 63:359-365.
    • (2003) Meat Sci. , vol.63 , pp. 359-365
    • Marcoux, M.1    Bernier, J.F.2    Pomar, C.3
  • 30
    • 0025089915 scopus 로고
    • Immunoaffinity chromatography and a biotin-streptavidin amplified enzymeimmunoassay for sensitive and specific estimation of estradiol-17 beta
    • Meyer H.H., Sauerwein H., Mutayoba B.M. Immunoaffinity chromatography and a biotin-streptavidin amplified enzymeimmunoassay for sensitive and specific estimation of estradiol-17 beta. J. Steroid Biochem. 1990, 35:263-269.
    • (1990) J. Steroid Biochem. , vol.35 , pp. 263-269
    • Meyer, H.H.1    Sauerwein, H.2    Mutayoba, B.M.3
  • 31
    • 0037387209 scopus 로고    scopus 로고
    • Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse
    • Misso M.L., Murata Y., Boon W.C., Jones M.E., Britt K.L., Simpson E.R. Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse. Endocrinology 2003, 144:1474-1480.
    • (2003) Endocrinology , vol.144 , pp. 1474-1480
    • Misso, M.L.1    Murata, Y.2    Boon, W.C.3    Jones, M.E.4    Britt, K.L.5    Simpson, E.R.6
  • 32
    • 38449087228 scopus 로고    scopus 로고
    • Perinatal and postnatal exposure to bisphenol a increases adipose tissue mass and serum cholesterol level in mice
    • Miyawaki J., Sakayama K., Kato H., Yamamoto H., Masuno H. Perinatal and postnatal exposure to bisphenol a increases adipose tissue mass and serum cholesterol level in mice. J. Atheroscler. Thromb. 2007, 14:245-252.
    • (2007) J. Atheroscler. Thromb. , vol.14 , pp. 245-252
    • Miyawaki, J.1    Sakayama, K.2    Kato, H.3    Yamamoto, H.4    Masuno, H.5
  • 33
    • 0030893546 scopus 로고    scopus 로고
    • Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol
    • Nagel S.C., vom Saal F.S., Thayer K.A., Dhar M.G., Boechler M., Welshons W.V. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. Environ. Health Perspect. 1997, 105:70-76.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 70-76
    • Nagel, S.C.1    vom Saal, F.S.2    Thayer, K.A.3    Dhar, M.G.4    Boechler, M.5    Welshons, W.V.6
  • 38
    • 77951961782 scopus 로고    scopus 로고
    • Lifetime cardiovascular risk of childhood obesity
    • Raghuveer G. Lifetime cardiovascular risk of childhood obesity. Am. J. Clin. Nutr. 2010, 91:1514S-1519S.
    • (2010) Am. J. Clin. Nutr. , vol.91
    • Raghuveer, G.1
  • 39
    • 78649469940 scopus 로고    scopus 로고
    • Obesity in children & adolescents
    • Raj M., Kumar R.K. Obesity in children & adolescents. Indian J. Med. Res. 2010, 132:598-607.
    • (2010) Indian J. Med. Res. , vol.132 , pp. 598-607
    • Raj, M.1    Kumar, R.K.2
  • 40
    • 24644453899 scopus 로고    scopus 로고
    • Descriptive epidemiology and health consequences of childhood obesity
    • Reilly J.J. Descriptive epidemiology and health consequences of childhood obesity. Best Pract. Res. Clin. Endocrinol. Metab. 2005, 19:327-341.
    • (2005) Best Pract. Res. Clin. Endocrinol. Metab. , vol.19 , pp. 327-341
    • Reilly, J.J.1
  • 42
    • 0034858392 scopus 로고    scopus 로고
    • Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels
    • Rubin B.S., Murray M.K., Damassa D.A., King J.C., Soto A.M. Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels. Environ. Health Perspect. 2001, 109:675-680.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 675-680
    • Rubin, B.S.1    Murray, M.K.2    Damassa, D.A.3    King, J.C.4    Soto, A.M.5
  • 45
    • 0027546823 scopus 로고
    • Plasma levels of several androgens and estrogens from birth to puberty in male domestic pigs
    • Schwarzenberger F., Toole G.S., Christie H.L., Raeside J.I. Plasma levels of several androgens and estrogens from birth to puberty in male domestic pigs. Acta Endocrinol. (Copenh.) 1993, 128:173-177.
    • (1993) Acta Endocrinol. (Copenh.) , vol.128 , pp. 173-177
    • Schwarzenberger, F.1    Toole, G.S.2    Christie, H.L.3    Raeside, J.I.4
  • 46
    • 80051492645 scopus 로고    scopus 로고
    • Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
    • Semirale A.A., Zhang X.W., Wiren K.M. Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation. J. Cell. Biochem. 2011, 112:1773-1786.
    • (2011) J. Cell. Biochem. , vol.112 , pp. 1773-1786
    • Semirale, A.A.1    Zhang, X.W.2    Wiren, K.M.3
  • 48
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • Singh R., Artaza J.N., Taylor W.E., Gonzalez-Cadavid N.F., Bhasin S. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology 2003, 144:5081-5088.
    • (2003) Endocrinology , vol.144 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 49
    • 0035004535 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects
    • Skakkebaek N.E., Rajpert-De Meyts E., Main K.M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum. Reprod. 2001, 16:972-978.
    • (2001) Hum. Reprod. , vol.16 , pp. 972-978
    • Skakkebaek, N.E.1    Rajpert-De Meyts, E.2    Main, K.M.3
  • 51
    • 0035092875 scopus 로고    scopus 로고
    • Validation of dual energy X-ray absorptiometry (DXA) by comparison with chemical analysis of dogs and cats
    • Speakman J.R., Booles D., Butterwick R. Validation of dual energy X-ray absorptiometry (DXA) by comparison with chemical analysis of dogs and cats. Int. J. Obes. Relat. Metab. Disord. 2001, 25:439-447.
    • (2001) Int. J. Obes. Relat. Metab. Disord. , vol.25 , pp. 439-447
    • Speakman, J.R.1    Booles, D.2    Butterwick, R.3
  • 52
    • 84870255429 scopus 로고    scopus 로고
    • Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance
    • Stubbins R.E., Holcomb V.B., Hong J., Nunez N.P. Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance. Eur. J. Nutr. 2011, 10.1007/s00394-011-0266-4.
    • (2011) Eur. J. Nutr.
    • Stubbins, R.E.1    Holcomb, V.B.2    Hong, J.3    Nunez, N.P.4
  • 53
    • 34447311377 scopus 로고    scopus 로고
    • Semen quality of fertile US males in relation to their mothers' beef consumption during pregnancy
    • Swan S.H., Liu F., Overstreet J.W., Brazil C., Skakkebaek N.E. Semen quality of fertile US males in relation to their mothers' beef consumption during pregnancy. Hum. Reprod. 2007, 22:1497-1502.
    • (2007) Hum. Reprod. , vol.22 , pp. 1497-1502
    • Swan, S.H.1    Liu, F.2    Overstreet, J.W.3    Brazil, C.4    Skakkebaek, N.E.5
  • 54
    • 68349091505 scopus 로고    scopus 로고
    • The early life environment and the epigenome
    • Szyf M. The early life environment and the epigenome. Biochim. Biophys. Acta 2009, 1790:878-885.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 878-885
    • Szyf, M.1
  • 55
    • 78149330579 scopus 로고    scopus 로고
    • Association of adolescent obesity with risk of severe obesity in adulthood
    • The N.S., Suchindran C., North K.E., Popkin B.M., Gordon-Larsen P. Association of adolescent obesity with risk of severe obesity in adulthood. JAMA 2010, 304:2042-2047.
    • (2010) JAMA , vol.304 , pp. 2042-2047
    • The, N.S.1    Suchindran, C.2    North, K.E.3    Popkin, B.M.4    Gordon-Larsen, P.5
  • 56
    • 33845312652 scopus 로고    scopus 로고
    • Chronic exposure of mice to environmentally relevant, low doses of cadmium leads to early renal damage, not predicted by blood or urine cadmium levels
    • Thijssen S., Maringwa J., Faes C., Lambrichts I., Van Kerkhove E. Chronic exposure of mice to environmentally relevant, low doses of cadmium leads to early renal damage, not predicted by blood or urine cadmium levels. Toxicology 2007, 229:145-156.
    • (2007) Toxicology , vol.229 , pp. 145-156
    • Thijssen, S.1    Maringwa, J.2    Faes, C.3    Lambrichts, I.4    Van Kerkhove, E.5
  • 59
  • 60
    • 42149190626 scopus 로고    scopus 로고
    • Aromatase and 11beta-hydroxysteroid dehydrogenase 2 localisation in the testes of pigs from birth to puberty linked to changes of hormone pattern and testicular morphology
    • Wagner A., Claus R. Aromatase and 11beta-hydroxysteroid dehydrogenase 2 localisation in the testes of pigs from birth to puberty linked to changes of hormone pattern and testicular morphology. Reprod. Fertil. Dev. 2008, 20:505-512.
    • (2008) Reprod. Fertil. Dev. , vol.20 , pp. 505-512
    • Wagner, A.1    Claus, R.2
  • 61


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.