Chronic exposure of mice to environmentally relevant, low doses of cadmium leads to early renal damage, not predicted by blood or urine cadmium levels

Toxicology

Volumn 229, Issue 1-2, 2007, Pages 145-156

  Thijssen, Sandy ^a   Maringwa, John ^b   Faes, Christel ^b   Lambrichts, Ivo ^a   Van Kerkhove, Emmy ^a  

^a HASSELT UNIVERSITY   (Belgium)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

Cadmium; Environmentally relevant; Histology; Low exposure; Proteinuria; Proximal tubule

Indexed keywords

CADMIUM; DRINKING WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYMURIA; GLUCOSURIA; HISTOPATHOLOGY; KIDNEY; KIDNEY CORTEX; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; LIVER LEVEL; LYSOSOME; MOUSE; MOUSE STRAIN; MULTIVARIATE ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; STATISTICAL SIGNIFICANCE; URINE LEVEL;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL MARKERS; CADMIUM CHLORIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENVIRONMENTAL EXPOSURE; KIDNEY; KIDNEY CORTEX; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; LIVER; MALE; MICE; MICE, INBRED C57BL; MULTIVARIATE ANALYSIS; PHOTOMICROGRAPHY; PROTEINURIA; REGRESSION ANALYSIS; SPECTROPHOTOMETRY, ATOMIC; TIME FACTORS; WEIGHT GAIN;

ANIMALIA;

EID: 33845312652     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.10.011     Document Type: Article

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