Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: Evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor γ2

Endocrinology

Volumn 141, Issue 2, 2000, Pages 649-656

  Dieudonne, M N ^a   Pecquery, R ^a   Leneveu, M C ^a   Giudicelli, Y ^a  

^a CENTRE HOSPITALIER INTERCOMMUNAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; ESTRADIOL; ESTROGEN; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HORMONE RECEPTOR BLOCKING AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; SOMATOMEDIN C RECEPTOR; TESTOSTERONE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; BODY DISTRIBUTION; BODY FAT; CELL DIFFERENTIATION; CELL PROLIFERATION; CULTURE MEDIUM; ENZYME ACTIVITY; EPIDIDYMIS FAT; FEMALE; GROWTH RATE; HORMONE ACTION; MALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SEX DIFFERENCE;

EID: 0034465232     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.2.7293     Document Type: Article

References (57)

1. Fat cell metabolism in different regions in women: Effect of menstrual cycle, pregnancy and lactation
2. Regional adipose tissue metabolism in men and postmenopausal women
3. Long-term testosterone administration increases visceral fat in female to male transsexuals
4. Adipose tissue distribution and function
5. Transcriptional regulation of gene expression during adipocyte differentiation
6. Molecular events in adipose development
7. Cellular and molecular aspect of adipose tissue development
8. Ectopic expression of the CAAT/enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells
9. Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and CEBPα
10. mPPARγ2: Tissue specific regulator of an adipocyte enhancer
11. Hormonal regulation of adipose differentiation
12. Regulation of adipocyte development
13. Control of adipocyte differentiation
14. Promotion of human adipocyte precursor replication by 17-beta estradiol in culture
15. Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells
16. Effects of steroid hormones on differentiation of adipose precursor cells in primary culture
17. Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anti-carcinogenic steroids
18. Dehydroepiandrosterone attenuates preadipocyte growth in primary cultures of stromal-vascular cells
19. Dehydroepiandrosterone reduces proliferation and differentiation of 3T3L1 preadipocytes
20. Nuclear estradiol binding in rat adipocytes. Regional variations and regulatory influence of hormones
21. Up-regulation of androgen receptor binding in male rat fat pad adipose precursor cells exposed to testosterone: Study in a whole cell assay system
22. Androgen receptor in cultured rat adipose precursor cells during proliferation and differentiation: Regional specificities and regulation by testosterone
23. Identification of estrogen receptor in human adipose tissue and adipocytes
24. Androgen binding to ammonium sulfate precipitates of human adipose tissue cytosols
25. Androgen receptors in hamster white adipose tissue and their precursor cells: Regional variations and modulation by androgens
26. Estrogen binding sites in hamster white adipose tissue: Sex- and -site related variations, modulation by testosterone
27. Influence of ovariectomy and regional fat distribution on the membranous transducing system controlling lipolysis in rat fat cells
28. Development of a chemically defined serum free medium for differentiation of rat adipose precursor cells
29. TNFα increase the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase
30. Participation of one isoenzyme of cytosolic glycerophosphate deshydrogenase in adipose conversion of 3T3 cells
31. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein dye binding
32. Enhanced androgen sensitivity in serum-free medium of a subline of the LNCaP human prostate cancer cell line
33. Effects of oestrogens on cell proliferation and cell cycle kinetics. A hypothesis on the cell cycle effects of antioestrogens
34. Estrogen regulation of human osteoblastic cell proliferation and differentiation
35. Evidence for a regional-specific control of rat preadipocyte proliferation and differentiation by the androgenic status
36. Varying capacities for replication of rat adipocytes precursor clones and adipose tissue growth
37. Sex an depot-specific stimulation of creatine kinase B in rat adipose tissues by gonadal steroids
38. Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: Dexamethasone and estradiol stimulate leptin release in women, but not in men
39. Capacity of adipose tissue to promote growth and metastasic of a murine mammary carcinoma: Effect of estrogens and progesterone
40. Androgens regulate proliferation of human prostate cancer cells in culture by increasing transforming growth factor (TGFα) and epidermal growth factor (EGF)/TGFα receptor
41. Regulation of uterine epidermal growth factor (EGF) receptors by estrogen in the mature rat and during the estrous cycle
42. IGF1: A mitogen involved in differentiation processes in mammalian cells
43. Fatty acids as signal transducing molecules involvement in the differentiation of preadipose to adipose cells
44. Proliferation and differentiation of rat adipose precursor cells in chemically defined medium: Differential action of anti-adipogenic agents
45. Expression and possible role of sex steroid receptors in rat and human preadipocytes during adipogenesis
46. Pharmacological and clinical studies of the antiandrogen anandron
47. Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the PPAR in hepatic cells
48. Gene regulation by steroid hormones
49. Induction of PPARγ during the conversion of 3T3 fibroblasts into adipocytes is mediated by CEBPβ, CEBPδ and glucocorticoids
50. IGF1 is an essential regulator of the differentiation of 3T3L1 adipocytes
51. Dehydroepiandrosterone-sulfate, body fat distribution and insulin in obese men
52. Expression and hormonal regulation of coactivator and corepressor genes
53. Effects of testosterone and estrogens on deltoid and trochanter adipocytes in two cases of transsexualism
54. Regional adipocyte precursors in the female rat: Influence of ovarian factors
55. Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma
56. Estrogen induced production of a peroxisome proliferator activated receptor (PPAR) ligand in a PPAR gamma expressing tissue