Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theaflavin-3,3'-digallate from black tea in NIH3T3 cells

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 4, 1999, Pages 1416-1421

  Chen, Yen Chou ^a   Liang, Yu Chih ^a   Lin Shiau, Shoei Yn ^b   Ho, Chi Tang ^c   Lin, Jen Kun ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

AP 1 binding activity; Black tea; PKC; Theaflavin 3,3' digallate; TPA; Tumor promotion

Indexed keywords

ANTIOXIDANT; DRUG DERIVATIVE; FUSED ALICYCLIC AROMATIC COMPOUND; GALLIC ACID; MYELIN BASIC PROTEIN; PHENOL DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; POLYMER; POLYPHENOLS; PROTEIN KINASE C; QUERCETIN; THEAFLAVINE DIGALLATE; TRANSCRIPTION FACTOR AP 1; TUMOR PROMOTER;

ANIMAL; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL STRAIN 3T3; CHEMISTRY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; METABOLISM; MOUSE; PROMOTER REGION; TEA; TRANSCRIPTION REGULATION; TUMOR GROWTH; TUMOR PROMOTION;

3T3 CELLS; ANIMALS; ANTIOXIDANTS; BIFLAVONOIDS; CATECHIN; FLAVONOIDS; GALLIC ACID; MICE; PHENOLS; POLYMERS; PROTEIN KINASE C; TEA; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

ANIMALIA; CAMELLIA SINENSIS;

EID: 0032915853     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf981099k     Document Type: Article

References (29)

1. Birt, D. F.; Walker, B.; M. Tibbels, G.; Bresnick, E. Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis 1986, 7, 959-963.
2. Blumber, P. M. Protein kinase C as the receptor the phorbol ester tumor promoter. Cancer Res. 1988, 48, 1-8.
3. Carter, T. H. Mechanism of environmental Carcinogenesis; CRC Press: Boca Raton, FL, 1987; pp 47-80.
4. Chen, C. W.; Ho, C. T. Antioxidant properties of polyphenols extracted from green and black tea. J. Food Lipids 1995, 2, 35-46.
5. Chen, Y. C.; Tsai, S. H.; Lin-Shiau, S. Y.; Lin, J. K. Elevation of apoptotic potential by anoxia/hyperoxia shift in NIH 3T3 cells. Mol. Cell. Biochem. 1998, in press.
6. Chomcynsk, P.; Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987, 162, 156-159.
7. Fujiki, H.; Tanaka Y.; Miyake, R., Kikkawa, U.; Nishizuka, Y.; Sugimura, T. Activation of calcium-activated, phospholipid-dependent protein kinase (protein kinase C) by new classes of tumor promoters: teleocidin and debromoaplysiatoxin. Biochem. Biophys. Res. Commun. 1984, 120, 339-343.
8. Grausz, J. D.; Fradelizi, D.; Dautry, F.; Monier, R.; Lehn, P. Modulation of c-fos and c-jun mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester. Eur. J. Immunol. 1986, 16, 1217-1221.
9. Huang, M. T.; Ferraro, T. Phenolic compounds in food and cancer prevention. In Phenolic Compounds in Food and Their Effects on Health II; Huang, M. T., Ho, C. T., Lee, C. Y., Eds.; ACS Symposium Series 507; American Chemical Society: Washington, DC, 1992; pp 8-34.
10. Huang, M. T.; Ferraro, T. Phenolic compounds in food and cancer prevention. In Phenolic Compounds in Food and Their Effects on Health II; Huang, M. T., Ho, C. T., Lee, C. Y., Eds.; ACS Symposium Series 507; American Chemical Society: Washington, DC, 1992; pp 8-34.
11. Huang, T. S.; Lee, S. C.; Lin, J. K. Suppression of c-Jun/AP-1 activation by an inhibitory of tumor promotion in mouse fibroblast cells. Proc. Natl. Acad. Sci. U.S.A. 1991, 88, 5292-5296.
12. Katiyar, S. K.; Agarwal, R.; Ekker, S.; Wood, G. S.; Mukhtar, H. Protection against 12-O-tetradecanoyl phorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea. Carcinogenesis 1993a, 14, 361-365.
13. Katiyar, S. K.; Agarwal, R.; Zaim, M. T.; Mukhtar H. Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea. Carcinogenesis 1993b, 14, 849-855.
14. Lee, S. F.; Lin, J. K. Inhibitory effects of phytopolyphenols on TPA-induced transformation PKC activation and c-Jun expression in mouse fibroblast cells. Nutr, Cancer 1997, 28, 177-183.
15. Lerman, M. I., Colburn, N. H. Tumor promotion: Biological Approaches for Mechanistic Studies and Assay Systems; Raven Press: New York, 1987; pp 357-385.
16. Liang, Y. C.; Lin-Shiau, S. Y.; Chen, C. F.; Lin, J. K. Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J. Cell. Biochem. 1997, 67, 55-65.
17. Lin, Y. L.; Lin, J. K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kB. Mol. Pharmacol. 1997, 52, 465-472.
18. Lin, Y. L.; Juan, I. M.; Liang, Y. C.; Lin, J. K. Composition of polyphenols in flesh tea leaves and association of their oxygen-radical-absorbing capacity with antiproliferative actions in fibroblast cells. J. Agric. Food Chem. 1996, 44, 1387-1394.
19. Maniatis, T.; Firstsch, E. F.; Sambrook, J. Molecular cloning: a laboratory manual; Cold Spring Harbor Laboratory Press: New York, 1989.
20. Nishina, H.; Sato, H.; Suzuki, T.; Sato, M.; Iba, H. Isolation and characterization of fra-2, an additional number of the fos gene family. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 3619-3623.
21. Nishizuka, Y. The family of protein kinase C for signal transduction. J. Am. Med. Assoc. 1989, 262, 1826-1833.
22. Ransone, L. J.; Verma, I. M. Nuclear proto-oncogene fos and jun. Annu. Rev. Cell Biol. 1990, 6, 539-557.
23. Ryder, K.; Nathans, D. Induction of proto-oncogene c-Jun by serum growth factors. Proc. Natl. Acad. Sci. U.S.A. 1988, 85, 9464-9467.
24. Ryseck, R. P.; Hirai, S. I.; Yaniv, M.; Bravo, R. Transcription activation of c-jun during the G0/G1 transition in mouse fibroblasts. Nature 1988, 34, 535-537.
25. Shi, S. T.; Wang, Z. Y.; Smith, T. J.; Hong, J. Y.; Chen, W. F.; Ho, C. T.; Yang C. S. Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation and lung tumorigenesis in A/J mice. Cancer Res. 1994, 54, 4641-4647.
26. Slaga, T. J. Overview of tumor promotion in animals. Environ. Health Perspect. 1983, 50, 3-14.
27. Wang, Z. Y.; Huang, M. T.; Lou, Y. R.;Xie, J. G.; Reuhl, K. R.; Newmark, H. L.; Ho, C. T.; Yang, C. S.; Conney, A. H. Inhibitory effects of black tea, green tea, decaffeinated black tea and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice. Cancer Res. 1994, 54, 3428-3435.
28. Weinstein, I. B. The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment-twenty-seventh G.H.A. Clows Memorial Award Lecture. Cancer Res. 1988, 48, 4135-4143.
29. Wu, W. S.; Lin, J. K.; Wu, F. Y. H. Differential induction of c-fos and c-jun proto-oncogenes and AP-1 activity by tumor promoter 12-O-tetradecanoyl phorbol 13-acetate in cells at different stages of tumor promotion in vitro. Oncogene 1992, 7, 2287-2294.