Non-classical membrane trafficking processes galore

Journal of Cellular Physiology

Volumn 227, Issue 12, 2012, Pages 3722-3730

  Chua, Christelle En Lin ^a   Lim, Yi Shan ^a   Lee, Min Goo ^b   Tang, Bor Luen ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; ALPHA INTEGRIN; FIBROBLAST GROWTH FACTOR 2; GOLGI REASSEMBLY STACKING PROTEIN; INTERLEUKIN 1BETA; PROTEIN; UNCLASSIFIED DRUG;

AUTOPHAGY; CELL MEMBRANE TRANSPORT; EXOCYTOSIS; LYSOSOME; MITOCHONDRION; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; REVIEW;

ANIMALS; BIOLOGICAL TRANSPORT; EXOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR MEMBRANES;

EID: 84865415457     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24082     Document Type: Review

References (121)

1. Abrahamsen H, Stenmark H. 2010. Protein secretion: Unconventional exit by exophagy. Curr Biol 20: R415-R418.
2. Alto NM, Soderling J, Scott JD. 2002. Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics. J Cell Biol 158: 659-668.
3. Andrade-Navarro MA, Sanchez-Pulido L, McBride HM. 2009. Mitochondrial vesicles: An ancient process providing new links to peroxisomes. Curr Opin Cell Biol 21: 560-567.
4. Andrei C, Dazzi C, Lotti L, Torrisi MR, Chimini G, Rubartelli A. 1999. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol Biol Cell 10: 1463-1475.
5. Andrei C, Margiocco P, Poggi A, Lotti LV, Torrisi MR, Rubartelli A. 2004. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes. Proc Natl Acad Sci USA 101: 9745-9750.
6. Babst M. 2011. MVB vesicle formation: ESCRT-dependent, ESCRT-independent and everything in between. Curr Opin Cell Biol 23: 452-457.
7. Banerjee R, Beal MF, Thomas B. 2010. Autophagy in neurodegenerative disorders: Pathogenic roles and therapeutic implications. Trends Neurosci 33: 541-549.
8. Beau I, Mehrpour M, Codogno P. 2011. Autophagosomes and human diseases. Int J Biochem Cell Biol 43: 460-464.
9. Beck R, Rawet M, Ravet M, Wieland FT, Cassel D. 2009. The COPI system: Molecular mechanisms and function. FEBS Lett 583: 2701-2709.
10. Becker CE, Creagh EM, O'Neill LAJ. 2009. Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion. J Biol Chem 284: 34531-34537.
11. Beumer JH, Tawbi H. 2010. Role of histone deacetylases and their inhibitors in cancer biology and treatment. Curr Clin Pharmacol 5: 196-208.
12. Bianco F, Pravettoni E, Colombo A, Schenk U, Möller T, Matteoli M, Verderio C. 2005. Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J Immunol 174: 7268-7277.
13. Blott EJ, Griffiths GM. 2002. Secretory lysosomes. Nat Rev Mol Cell Biol 3: 122-131.
14. Bonifacino JS, Glick BS. 2004. The mechanisms of vesicle budding and fusion. Cell 116: 153-166.
15. Bossard C, Laurell H, Van den Berghe L, Meunier S, Zanibellato C, Prats H. 2003. Translokin is an intracellular mediator of FGF-2 trafficking. Nat Cell Biol 5: 433-439.
16. Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S. 2000. Role of COPI in phagosome maturation. J Biol Chem 275: 15717-15727.
17. Bours MJL, Dagnelie PC, Giuliani AL, Wesselius A, Di Virgilio F. 2011. P2 receptors and extracellular ATP: A novel homeostatic pathway in inflammation. Front Biosci 3: 1443-1456.
18. Braschi E, Zunino R, McBride HM. 2009. MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Rep 10: 748-754.
19. Bruns C, McCaffery JM, Curwin AJ, Duran JM, Malhotra V. 2011. Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion. J Cell Biol 195: 979-992.
20. Bui M, Gilady SY, Fitzsimmons REB, Benson MD, Lynes EM, Gesson K, Alto NM, Strack S, Scott JD, Simmen T. 2010. Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem 285: 31590-31602.
21. Cabral M, Anjard C, Malhotra V, Loomis WF, Kuspa A. 2010. Unconventional secretion of AcbA in Dictyostelium discoideum through a vesicular intermediate. Eukaryot Cell 9: 1009-1017.
22. Camussi G, Deregibus MC, Bruno S, Cantaluppi V, Biancone L. 2010. Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int 78: 838-848.
23. Carta S, Tassi S, Semino C, Fossati G, Mascagni P, Dinarello CA, Rubartelli A. 2006. Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: Role of microtubules. Blood 108: 1618-1626.
24. Chang JL, Tsai HJ. 1996. Carp cDNA sequence encoding a putative diazepam-binding inhibitor/endozepine/acyl-CoA-binding protein. Biochim Biophys Acta 1298: 9-11.
25. Chua CEL, Gan BQ, Tang BL. 2011. Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation. Cell Mol Life Sci 68: 3349-3358.
26. Cocucci E, Racchetti G, Meldolesi J. 2009. Shedding microvesicles: Artefacts no more. Trends Cell Biol 19: 43-51.
27. Collins BM. 2008. The structure and function of the retromer protein complex. Traffic 9: 1811-1822.
28. Costa E, Guidotti A. 1991. Diazepam binding inhibitor (DBI): A peptide with multiple biological actions. Life Sci 49: 325-344.
29. Csordás G, Hajnóczky G. 2009. SR/ER-mitochondrial local communication: Calcium and ROS. Biochim Biophys Acta 1787: 1352-1362.
30. Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. 2011. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J 30: 4701-4711.
31. Duran JM, Anjard C, Stefan C, Loomis WF, Malhotra V. 2010. Unconventional secretion of Acb1 is mediated by autophagosomes. J Cell Biol 188: 527-536.
32. Ebert AD, Laussmann M, Wegehingel S, Kaderali L, Erfle H, Reichert J, Lechner J, Beer HD, Pepperkok R, Nickel W. 2010. Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion. Traffic 11: 813-826.
33. Eder C. 2009. Mechanisms of interleukin-1beta release. Immunobiology 214: 543-553.
34. Faergeman NJ, Knudsen J. 2002. Acyl-CoA binding protein is an essential protein in mammalian cell lines. Biochem J 368: 679-682.
35. Feinstein TN, Linstedt AD. 2008. GRASP55 regulates Golgi ribbon formation. Mol Biol Cell 19: 2696-2707.
36. Février B, Raposo G. 2004. Exosomes: Endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol 16: 415-421.
37. Fujimoto M, Hayashi T. 2011. New insights into the role of mitochondria-associated endoplasmic reticulum membrane. Int Rev Cell Mol Biol 292: 73-117.
38. Fung KYC, Brierley GV, Henderson S, Hoffmann P, McColl SR, Lockett T, Head R, Cosgrove L. 2011. Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response. J Proteome Res 10: 1860-1869.
39. Gardella S, Andrei C, Lotti LV, Poggi A, Torrisi MR, Zocchi MR, Rubartelli A. 2001. CD8(+) T lymphocytes induce polarized exocytosis of secretory lysosomes by dendritic cells with release of interleukin-1beta and cathepsin D. Blood 98: 2152-2159.
40. Gardella S, Andrei C, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, Rubartelli A. 2002. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep 3: 995-1001.
41. Gee H, Roh S, Tang B, Kim K, Lee M. 2011. Rescue of deltaF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway. Cell 146: 746-760.
42. Gerdes HH, Carvalho RN. 2008. Intercellular transfer mediated by tunneling nanotubes. Curr Opin Cell Biol 20: 470-475.
43. Gerdes HH, Bukoreshtliev NV, Barroso JFV. 2007. Tunneling nanotubes: A new route for the exchange of components between animal cells. FEBS Lett 581: 2194-2201.
44. Giuliani F, Grieve A, Rabouille C. 2011. Unconventional secretion: A stress on GRASP. Curr Opin Cell Biol 23: 498-504.
45. Grimm S. 2011. The ER-mitochondria interface: The social network of cell death. Biochim Biophys Acta 1823: 327-334.
46. Gu F, Aniento F, Parton RG, Gruenberg J. 1997. Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes. J Cell Biol 139: 1183-1195.
47. Gurke S, Barroso JFV, Gerdes HH. 2008. The art of cellular communication: Tunneling nanotubes bridge the divide. Histochem Cell Biol 129: 539-550.
48. György B, Szabó TG, Pásztói M, Pál Z, Misják P, Aradi B, László V, Pállinger E, Pap E, Kittel A, Nagy G, Falus A, Buzás EI. 2011. Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles. Cell Mol Life Sci 68: 2667-2688.
49. Holt OJ, Gallo F, Griffiths GM. 2006. Regulating secretory lysosomes. J Biochem 140: 7-12.
50. Huang H, Atshaves BP, Frolov A, Kier AB, Schroeder F. 2005. Acyl-coenzyme A binding protein expression alters liver fatty acyl-coenzyme A metabolism. Biochemistry 44: 10282-10297.
51. Hurley JH. 2008. ESCRT complexes and the biogenesis of multivesicular bodies. Curr Opin Cell Biol 20: 4-11.
52. Hurley JH. 2010. The ESCRT complexes. Crit Rev Biochem Mol Biol 45: 463-487.
53. Irion U, St Johnston D. 2007. Bicoid RNA localization requires specific binding of an endosomal sorting complex. Nature 445: 554-558.
54. Jensen D, Schekman R. 2011. COPII-mediated vesicle formation at a glance. J Cell Sci 124: 1-4.
55. Karbowski M, Neutzner A. 2012. Neurodegeneration as a consequence of failed mitochondrial maintenance. Acta Neuropathol 123: 157-171.
56. Karhinen L, Bastos RN, Jokitalo E, Makarow M. 2005. Endoplasmic reticulum exit of a secretory glycoprotein in the absence of sec24p family proteins in yeast. Traffic 6: 562-574.
57. Kinseth MA, Anjard C, Fuller D, Guizzunti G, Loomis WF, Malhotra V. 2007. The Golgi-associated protein GRASP is required for unconventional protein secretion during development. Cell 130: 524-534.
58. Kroemer G, Mariño G, Levine B. 2010. Autophagy and the integrated stress response. Mol Cell 40: 280-293.
59. Lee TH, D'Asti E, Magnus N, Al-Nedawi K, Meehan B, Rak J. 2011. Microvesicles as mediators of intercellular communication in cancer-The emerging science of cellular 'debris'. Semin Immunopathol 33: 455-467.
60. Lee J, Giordano S, Zhang J. 2012. Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling. Biochem J 441: 523-540.
61. Lelliott CJ, Vidal-Puig A. 2009. PGC-1beta: A co-activator that sets the tone for both basal and stress-stimulated mitochondrial activity. Adv Exp Med Biol 646: 133-139.
62. Li W, Bengtson MH, Ulbrich A, Matsuda A, Reddy VA, Orth A, Chanda SK, Batalov S, Joazeiro CAP. 2008. Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS ONE 3: e1487.
63. Ma C, Agrawal G, Subramani S. 2011. Peroxisome assembly: Matrix and membrane protein biogenesis. J Cell Biol 193: 7-16.
64. MacKenzie A, Wilson HL, Kiss-Toth E, Dower SK, North RA, Surprenant A. 2001. Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity 15: 825-835.
65. Manjithaya R, Subramani S. 2011. Autophagy: A broad role in unconventional protein secretion? Trends Cell Biol 21: 67-73.
66. Manjithaya R, Anjard C, Loomis WF, Subramani S. 2010. Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation. J Cell Biol 188: 537-546.
67. Mariño G, Madeo F, Kroemer G. 2011. Autophagy for tissue homeostasis and neuroprotection. Curr Opin Cell Biol 23: 198-206.
68. Mathew R, White E. 2011. Autophagy in tumorigenesis and energy metabolism: Friend by day, foe by night. Curr Opin Genet Dev 21: 113-119.
69. Mathivanan S, Ji H, Simpson RJ. 2010. Exosomes: Extracellular organelles important in intercellular communication. J Proteomics 73: 1907-1920.
70. McGough IJ, Cullen PJ. 2011. Recent advances in retromer biology. Traffic 12: 963-971.
71. Meunier S, Navarro MGJ, Bossard C, Laurell H, Touriol C, Lacazette E, Prats H. 2009. Pivotal role of translokin/CEP57 in the unconventional secretion versus nuclear translocation of FGF2. Traffic 10: 1765-1772.
72. Neuspiel M, Schauss AC, Braschi E, Zunino R, Rippstein P, Rachubinski RA, Andrade-Navarro MA, McBride HM. 2008. Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol 18: 102-108.
73. Nickel W. 2011. The unconventional secretory machinery of fibroblast growth factor 2. Traffic 12: 799-805.
74. Nickel W, Rabouille C. 2009. Mechanisms of regulated unconventional protein secretion. Nat Rev Mol Cell Biol 10: 148-155.
75. Nickel W, Seedorf M. 2008. Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells. Annu Rev Cell Dev Biol 24: 287-308.
76. Oku M, Sakai Y. 2010. Peroxisomes as dynamic organelles: Autophagic degradation. FEBS J 277: 3289-3294.
77. Orci L, Palmer DJ, Ravazzola M, Perrelet A, Amherdt M, Rothman JE. 1993. Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins. Nature 362: 648-652.
78. Pizzirani C, Ferrari D, Chiozzi P, Adinolfi E, Sandonà D, Savaglio E, Di Virgilio F. 2007. Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells. Blood 109: 3856-3864.
79. Qu Y, Dubyak GR. 2009. P2×7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways. Purinergic Signal 5: 163-173.
80. Qu Y, Franchi L, Nunez G, Dubyak GR. 2007. Nonclassical IL-1 beta secretion stimulated by P2×7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol 179: 1913-1925.
81. Quinton PM. 1999. Physiological basis of cystic fibrosis: A historical perspective. Physiol Rev 79: S3-S22.
82. Rambold AS, Lippincott-Schwartz J. 2011. Mechanisms of mitochondria and autophagy crosstalk. Cell Cycle 10: 4032-4038.
83. Record M, Subra C, Silvente-Poirot S, Poirot M. 2011. Exosomes as intercellular signalosomes and pharmacological effectors. Biochem Pharmacol 81: 1171-1182.
84. Reggiori F, Klionsky DJ. 2002. Autophagy in the eukaryotic cell. Eukaryot Cell 1: 11-21.
85. Rosenfeldt MT, Ryan KM. 2011. The multiple roles of autophagy in cancer. Carcinogenesis 32: 955-963.
86. Rothman JE. 1994. Mechanisms of intracellular protein transport. Nature 372: 55-63.
87. Royle SJ. 2011. Mitotic moonlighting functions for membrane trafficking proteins. Traffic 12: 791-798.
88. Rubartelli A, Cozzolino F, Talio M, Sitia R. 1990. A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. EMBO J 9: 1503-1510.
89. Sadallah S, Eken C, Schifferli JA. 2011. Ectosomes as modulators of inflammation and immunity. Clin Exp Immunol 163: 26-32.
90. Santel A, Frank S. 2008. Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1. IUBMB Life 60: 448-455.
91. Schäfer T, Zentgraf H, Zehe C, Brügger B, Bernhagen J, Nickel W. 2004. Unconventional secretion of fibroblast growth factor 2 is mediated by direct translocation across the plasma membrane of mammalian cells. J Biol Chem 279: 6244-6251.
92. Schmitt K, Grimm A, Kazmierczak A, Strosznajder JB, Götz J, Eckert A. 2011. Insights into mitochondrial dysfunction: Aging, amyloid-β and Tau-A deleterious trio. Antioxid Redox Signal (in press).
93. Schorey JS, Bhatnagar S. 2008. Exosome function: From tumor immunology to pathogen biology. Traffic 9: 871-881.
94. Schotman H, Karhinen L, Rabouille C. 2008. dGRASP-mediated noncanonical integrin secretion is required for Drosophila epithelial remodeling. Dev Cell 14: 171-182.
95. Schotman H, Karhinen L, Rabouille C. 2009. Integrins mediate their unconventional, mechanical-stress-induced secretion via RhoA and PINCH in Drosophila. J Cell Sci 122: 2662-2672.
96. Seelenmeyer C, Wegehingel S, Tews I, Künzler M, Aebi M, Nickel W. 2005. Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1. J Cell Biol 171: 373-381.
97. Seelenmeyer C, Stegmayer C, Nickel W. 2008. Unconventional secretion of fibroblast growth factor 2 and galectin-1 does not require shedding of plasma membrane-derived vesicles. FEBS Lett 582: 1362-1368.
98. Sherer NM, Mothes W. 2008. Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends Cell Biol 18: 414-420.
99. Shorter J, Watson R, Giannakou ME, Clarke M, Warren G, Barr FA. 1999. GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. EMBO J 18: 4949-4960.
100. Shulga N, Pastorino JG. 2006. Acyl coenzyme A-binding protein augments bid-induced mitochondrial damage and cell death by activating mu-calpain. J Biol Chem 281: 30824-30833.
101. Simeone TA, Donevan SD, Rho JM. 2003. Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system. J Child Neurol 18: 39-48, discussion 49.
102. Simons M, Raposo G. 2009. Exosomes-vesicular carriers for intercellular communication. Curr Opin Cell Biol 21: 575-581.
103. Small SA. 2008. Retromer sorting: A pathogenic pathway in late-onset Alzheimer disease. Arch Neurol 65: 323-328.
104. Soubannier V, McLelland GL, Zunino R, Braschi E, Rippstein P, Fon EA, McBride HM. 2012. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr Biol 22: 135-141.
105. Strowig T, Henao-Mejia J, Elinav E, Flavell R. 2012. Inflammasomes in health and disease. Nature 481: 278-286.
106. Sullivan CP, Jay AG, Stack EC, Pakaluk M, Wadlinger E, Fine RE, Wells JM, Morin PJ. 2011. Retromer disruption promotes amyloidogenic APP processing. Neurobiol Dis 43: 338-345.
107. Swerdlow RH. 2011. Brain aging, Alzheimer's disease, and mitochondria. Biochim Biophys Acta 1812: 1630-1639.
108. Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W. 2004. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. Mol Biol Cell 15: 4011-4022.
109. Tang BL, Wang Y, Ong YS, Hong W. 2005. COPII and exit from the endoplasmic reticulum. Biochim Biophys Acta 1744: 293-303.
110. Temmerman K, Ebert AD, Müller HM, Sinning I, Tews I, Nickel W. 2008. A direct role for phosphatidylinositol-4, 5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic 9: 1204-1217.
111. Truscott KN, Brandner K, Pfanner N. 2003. Mechanisms of protein import into mitochondria. Curr Biol 13: R326-R337.
112. Turner N, Grose R. 2010. Fibroblast growth factor signalling: From development to cancer. Nat Rev Cancer 10: 116-129.
113. Vergés M. 2008. Retromer: Multipurpose sorting and specialization in polarized transport. Int Rev Cell Mol Biol 271: 153-198.
114. Wen L, Tang FL, Hong Y, Luo SW, Wang CL, He W, Shen C, Jung JU, Xiong F, Lee DH, Zhang QG, Brann D, Kim TW, Yan R, Mei L, Xiong WC. 2011. VPS35 haploinsufficiency increases Alzheimer's disease neuropathology. J Cell Biol 195: 765-779.
115. Wendler F, Tooze S. 2001. Syntaxin 6: The promiscuous behaviour of a SNARE protein. Traffic 2: 606-611.
116. Wiedemann N, Frazier AE, Pfanner N. 2004. The protein import machinery of mitochondria. J Biol Chem 279: 14473-14476.
117. Xiang Y, Wang Y. 2010. GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. J Cell Biol 188: 237-251.
118. Xilouri M, Stefanis L. 2010. Autophagy in the central nervous system: Implications for neurodegenerative disorders. CNS Neurol Disord Drug Targets 9: 701-719.
119. Yang Z, Klionsky DJ. 2010. Eaten alive: A history of macroautophagy. Nat Cell Biol 12: 814-822.
120. Yoo JS, Moyer BD, Bannykh S, Yoo HM, Riordan JR, Balch WE. 2002. Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway. J Biol Chem 277: 11401-11409.
121. Zehe C, Engling A, Wegehingel S, Schäfer T, Nickel W. 2006. Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2. Proc Natl Acad Sci USA 103: 15479-15484.