bicoid RNA localization requires specific binding of an endosomal sorting complex

Nature

Volumn 445, Issue 7127, 2007, Pages 554-558

  Irion, Uwe ^a,b   St Johnston, Daniel ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BICOID PROTEIN; MESSENGER RNA; PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

CELL ORGANELLE; CYTOPLASM; EGG; EMBRYO; FLY; MUTATION; PROTEIN; RNA;

3' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOSOME; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; UBIQUITINATION;

VERTEBRATA;

EID: 33846662786     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05503     Document Type: Article

References (30)

1. Frohnhöfer, H. G. & Nüsslein-Volhard, C. Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid. Nature 324, 120-125 (1986).
2. Berleth, T. et al. The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. EMBO J. 7, 1749-1756 (1988).
3. Driever, W. & Nüsslein-Volhard, C. A gradient of Bicoid protein in Drosophila embryos. Cell 54, 83-93 (1988).
4. Driever, W. & Nüsslein-Volhard, C. The Bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54, 95-104 (1988).
5. Arn, E. A., Cha, B. J., Theurkauf, W. E. & Macdonald, P. M. Recognition of a bicoid mRNA localization signal by a protein complex containing Swallow, Nod, and RNA binding proteins. Dev. Cell 4, 41-51 (2003).
6. St Johnston, D., Beuchle, D. & Nüsslein-Volhard, C. staufen, a gene required to localize maternal RNAs in the Drosophila egg. Cell 66, 51-63 (1991).
7. Ramos, A. et al. RNA recognition by a Staufen double-stranded RNA-binding domain. EMBO J. 19, 997-1009 (2000).
8. Babst, M. A protein's final ESCRT. Traffic 6, 2-9 (2005).
9. Babst, M., Katzmann, D. J., Snyder, W. B., Wendland, B. & Emr, S. D. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev. Cell 3, 283-289 (2002).
10. Vaccari, T. & Bilder, D. The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating Notch trafficking. Dev. Cell 9, 687-698 (2005).
11. Thompson, B. J. et al. Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev. Cell 9, 711-720 (2005).
12. Teo, H. et al. ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell 125, 99-111 (2006).
13. Frohnhöfer, H. G. & Nüsslein-Volhard, C. Maternal genes required for the anterior localization of bicoid activity in the embryo of Drosophila. Genes Dev. 1, 880-890 (1987).
14. Macdonald, P. M., Luk, S. K. & Kilpatrick, M. Protein encoded by the exuperantia gene is concentrated at sites of bicoid mRNA accumulation in Drosophila nurse cells but not in oocytes or embryos. Genes Dev. 5, 2455-2466 (1991).
15. Wilhelm, J. E. et al. Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes. J. Cell Biol. 148, 427-440 (2000).
16. Theurkauf, W. E. & Hazelrigg, T. I. In vivo analyses of cytoplasmic transport and cytoskeletal organization during Drosophila oogenesis: characterization of a multi-step anterior localization pathway. Development 125, 3655-3666 (1998).
17. Moon, W. & Hazelrigg, T. The Drosophila microtubule-associated protein Mini spindles is required for cytoplasmic microtubules in oogenesis. Curr. Biol. 14, 1957-1961 (2004).
18. Vogt, N., Koch, I., Schwarz, H., Schnorrer, F. & Nüsslein- Volhard, C. The γTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline. Development 133, 3963-3972 (2006).
19. Ferrandon, D., Elphick, L., Nüsslein-Volhard, C. & St Johnston, D. Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner. Cell 79, 1221-1232 (1994).
20. Weil, T. T., Forrest, K. M. & Gavis, E. R. Localization of bicoid mRNA in late oocytes is maintained by continual active transport. Dev. Cell 11, 251-262 (2006).
21. St Johnston, D., Driever, W., Berleth, T., Richstein, S. & Nüsslein-Volhard, C. Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. Development 107 (Suppl), 13-19 (1989).
22. Macdonald, P. M., Kerr, K., Smith, J. L. & Leask, A. RNA regulatory element BLE1 directs the early steps of bicoid mRNA localization. Development 118, 1233-1243 (1993).
23. Micklem, D. R., Adams, J., Grunert, S. & St Johnston, D. Distinct roles of two conserved Staufen domains in oskar mRNA localization and translation. EMBO J. 19, 1366-1377 (2000).
24. Martin, S. G., Leclerc, V., Smith-Litière, K. & St Johnston, D. The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen. Development 130, 4201-4215 (2003).
25. Teo, H., Perisic, O., Gonzalez, B. & Williams, R. L. ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes. Dev. Cell 7, 559-569 (2004).
26. Moberg, K. H., Schelble, S., Burdick, S. K. & Hariharan, I. K. Mutations in erupted, the Drosophila ortholog of mammalian Tumor Susceptibility Gene 101, elicit non-cell-autonomous overgrowth. Dev. Cell 9, 699-710 (2005).
27. Kamura, T. et al. Cloning and characterization of ELL-associated proteins EAP45 and EAP20. A role for yeast EAP-like proteins in regulation of gene expression by glucose. J. Biol. Chem. 276, 16528-16533 (2001).
28. Schmidt, A. E., Miller, T., Schmidt, S. L., Shiekhattar, R. & Shilatifard, A. Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II. J. Biol. Chem. 274, 21981-21985 (1999).
29. Jin, Y., Mancuso, J. J., Uzawa, S., Cronembold, D. & Cande, W. Z. The fission yeast homolog of the human transcription factor EAP30 blocks meiotic spindle pole body amplification. Dev. Cell 9, 63-73 (2005).
30. Putz, U., Skehel, P. & Kuhl, D. A tri-hybrid system for the analysis and detection of RNA-protein interactions. Nucleic Acids Res. 24, 4838-4840 (1996).