Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1264-1278

  Weldy, Chad S ^a   Luttrell, Ian P ^a   White, Collin C ^a   Morgan Stevenson, Vicki ^b   Bammler, Theo K ^a   Beyer, Richard P ^a   Afsharinejad, Zahra ^a   Kim, Francis ^b   Chitaley, Kanchan ^a   Kavanagh, Terrance J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Free radicals; GCLM knockout mouse; Glutamate cysteine ligase; Glutathione; Nitric oxide; Vascular reactivity

Indexed keywords

3 NITROTYROSINE; GLUTATHIONE; NITRIC OXIDE; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL REACTIVITY; CALCIUM SIGNALING; CONTROLLED STUDY; GCLM GENE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUTATHIONE METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ACETYLCHOLINE; ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ANIMALS; AORTA; CHOLINERGIC AGONISTS; CYCLIC GMP; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENYLEPHRINE; REACTIVE OXYGEN SPECIES; TRANSCRIPTOME; TYROSINE; VASOCONSTRICTION; VASODILATION;

MUS;

EID: 84865408270     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.006     Document Type: Article

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