GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension

Hypertension

Volumn 56, Issue 6, 2010, Pages 1137-1144

  Xie, He Hui ^a,b   Zhou, Shuang ^a,b   Chen, Dan Dan ^b,c   Channon, Keith M ^d   Su, Ding Feng ^a   Chen, Alex F ^a,b,c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

endothelial progenitor cell; GTP cyclohydrolase; nitric oxide synthase; tetrahydrobiopterin; thrombospondin 1

Indexed keywords

DEOXYCORTICOSTERONE ACETATE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; MACROGOL; N(G) NITROARGININE; NITRIC OXIDE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN; THROMBOSPONDIN 1;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIAL PROGENITOR CELL; HYPERTENSION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANGIOGENESIS INHIBITORS; ANIMALS; BIOPTERIN; CELL ADHESION; DESOXYCORTICOSTERONE; GTP CYCLOHYDROLASE; HYPERTENSION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; NITROARGININE; OXIDATIVE STRESS; POLYETHYLENE GLYCOLS; STEM CELLS; SUPEROXIDE DISMUTASE; SUPEROXIDES; THROMBOSPONDIN 1;

EID: 78650419148     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.160622     Document Type: Article

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