Modulating GSH synthesis using glutamate cysteine ligase transgenic and gene-targeted mice

Drug Metabolism Reviews

Volumn 40, Issue 3, 2008, Pages 465-477

  Botta, Dianne ^a   White, Collin C ^a   Vliet Gregg, Portia ^a   Mohar, Isaac ^a   Shi, Shengli ^a   McGrath, Monica B ^a   McConnachie, Lisa A ^a   Kavanagh, Terrance J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Acetaminophen; Gene targeting; Glutamate cysteine ligase; Glutathione; Liver injury; Mice; Transgenic

Indexed keywords

ANTIOXIDANT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MIFEPRISTONE; PARACETAMOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE TARGETING; GLUTATHIONE METABOLISM; LIVER INJURY; NONHUMAN; PROTEIN EXPRESSION; REVIEW; TRANSGENIC MOUSE;

ACETAMINOPHEN; ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; GENE TARGETING; GENOTYPE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; LIVER; LIVER DISEASES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE;

EID: 47649128397     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.1080/03602530802186587     Document Type: Review

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