Impairment of excitatory amino acid transporter activity by oxidative stress conditions in retinal cells: Effect of antioxidants

FASEB Journal

Volumn 11, Issue 2, 1997, Pages 154-163

  Agostinho, Paula ^a,b   Duarte, Carlos B ^a,b   Oliveira, Catarina R ^a,c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

antioxidants; D 3H asparte uptake; lipid peroxidation; melatonin; oxidation of proteins

Indexed keywords

2 (4 AMYLCINNAMIDO) 4 CHLOROBENZOIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALKADIENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ARACHIDONIC ACID; ASPARTIC ACID; BOVINE SERUM ALBUMIN; CARRIER PROTEIN; DITHIOTHREITOL; DIZOCILPINE; EXCITATORY AMINO ACID; FERROUS ASCORBATE; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GLUTATHIONE; LACTATE DEHYDROGENASE; MEGLUMINE; MELATONIN; PHOSPHOLIPASE A2; SODIUM; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CHICKEN; CONTROLLED STUDY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RETINA CELL;

ANIMALIA; BOVINAE; GALLUS GALLUS;

EID: 0031027249     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.2.9039958     Document Type: Article

References (57)

1. Sies, H. (1993) Strategies of antioxidant defense. Eur. J. Biochem. 215, 213-219
2. Coyle, J.T., and Puttfarcken, P. (1993) Oxidative stress, glutamate, and neurodegenerative diseases. Science 262, 689-695
3. Reiter, R. J. (1995) Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9, 526-533
4. Halliwell B., and Gutteridge J. M. C. (1985) Oxygen radicals and the nervous system. Trends Neurosci. 8, 22-26
5. Danbolt, N. C. (1994) The high affinity uptake system for excitatory amino acids in the brain. Prog. Neurobiol. 44, 377-396
6. Choi, D. W. (1987) Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7, 369-379
7. Rego, A. C., Santos, M. S., and Oliveira, C. R. (1996) Oxidative stress, hypoxia, and ischemia-like conditions increase the release of endogenous amino acids by distinct mechanisms in cultured retinal cells. J. Neurochem. 66, 2506-2516
8. Miyamoto, M., Murphy, T. H., Schnaar, R. L., and Coyle, J. T. (1989) Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. J. Pharmacol. Exp. Ther. 250, 1132-1140
9. Pellegrini-Gampietro, D. E., Cherici, G., Alesiani, M., Carla, V., and Moroni, F. (1990) Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 10, 1035-1041
10. Handelman, G. J., and Dratz, E. (1986) The role of antioxidants in the retina and retinal pigment epithelium and the nature of prooxidant-induced damage. Adv. Free Rad. Biol. Med. 2, 1-89
11. Neal, M. J., Cunningham, J. R., Huston, P. H., and Hogg, J. (1994) Effects of ischaemia on neurotransmitter release from isolated retina. J. Neurochem. 62, 1025-1033
12. Romano, C., Price M. T., and Olney, J. W. (1995) Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina. J. Neurochem. 65, 59-67
13. Facci, L., Leon, A., and Skaper, S. D. (1990) Excitatory amino acid neurotoxicity in cultured retinal neurons: involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors and effect of ganglioside GMI. J. Neurosci. Res. 27, 202-210
14. 2+ influx through glutamate receptor-associated channels in retina cells correlates with neuronal cell death. Eur. J. Pharmacol. 302, 153-162
15. Chen, L.-D., Melchiorri, D., Sewerynek, E., and Reiter, R. J. (1995) Retinal lipid peroxidation in vitro is inhibited by melatonin. Neurosci. Res. Commun. 17, 151-158
16. Agostinho, P., Duarte, C. B., Carvalho, A. P., and Oliveira, C. R. (1995) Modulation of N-methyl-D-aspartate receptor activity by oxidative stress conditions in chick retinal cells. Neurosc. Lett. 198, 193-196
17. 2+-induced oxidative stress. J. Neurochem. 67, 1153-1163
18. 3H]GABA in cultured chick retina cells. Brain Res. 655, 213-221
19. Huba, R., and Hofmann, H. D. (1990) Identification of GABAergic amacrine cell-like neurons developing in chick retinal monolayer cultures. Neurosci. Lett. 117, 37-42
20. Wässle, H., and Boycott, B. B. (1991) Functional architecture of the mammalian retina. Physiol. Rev. 71, 447-480
21. Buege, J. A., and Aust, S. D. (1967) Microsomal lipid peroxidation. In Methods of Enzymology (Colowick S. P., and Kaplan N. O., eds) Vol. 52, pp. 302-310, Academic Press, New York
22. Reed, C. F., Swisher, S. N., Marinetti, G. V., and Eden, E. G. (1960) Studies of the lipids of the erythrocyte. I. Quantitative analysis of the lipids of normal human red blood cells. J. Lab. Clin. Med. 56, 281-289
23. Sedmak, J. J., and Grossero, S. E. (1977) A rapid sensitive and versatile assay for protein using coomassie brilliant blue G 250. Ann. Biochem. 79, 544-552
24. Bergmeyer, H. U., and Brent, E. (1974) UV-assay with pyruvate and NADH. In Methods of Enzymatic Analysis (Bergmeyer, H. U., ed) pp. 574-579, Academic Press, New York
25. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63
26. Gutteridge, J. M. C., and Halliwell, B. (1990) The measurements and mechanism of lipid peroxidation in biological systems. Trends Biochem. Sci. 15, 129-135
27. Balcar, V. J., and Johnston, G. A. R. (1972) The strucutral specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices. J. Neurochem. 19, 2657-2666
28. Kelley, E. R., Buettner, G. R., and Burns, C. P. (1995) Relative α-tocopherol deficiency in cultured cells: free radical-mediated lipid peroxidation, lipid oxidizability, and cellular polyunsaturated fatty acid content. Arch. Biochem. Biophys. 319, 102-109
29. Littlefield, L. G., Joiner, E. K., Colyer, S. P., Sayer, A. M., and Frane, E. L. (1988) Modulation of radiation induced chromosome aberrations by DMSO, an •OH radical scavenger. 1. Dose response studies on human lymphocytes exposed to 220 KV X-rays. Int. J. Radiat. Biol. 53, 875-880
30. Tan, D.-X.; Chen, L. D., Poeggler, B., Manchester, L. C., and Reiter, R. J. (1993) Melatonin: a potent endogenous hydroxyl radical scavenger. Endocrine J. 1, 57-60
31. Katsuki, H., and Okuda, S. (1995) Arachidonic acid as a neurotoxic and neurotrophic substance. Prog. Neurobiol. 46, 607-636
32. Barbour, B., Szatkowski, M., Ingledew, N., and Attwell, D. (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature (London) 342, 918-920
33. Volterra, A. (1994) Inhibition of high affinity glutamate transport in neuronal and glial cells by arachidonic acid and oxygen-free radicals. Renal Physiol. Biochem. 17, 165-167
34. Trotti, D., Volterra, A., Lehre, K. P., Rossi, D., Gjesdal, O., Racagni, G., and Danbolt, N. (1995) Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane. J. Biol. Chem. 270, 9890-9895
35. + concentration increases in cultured retinal cells under oxidative stress conditions. Neurosci. Res. 25, 343-351
36. Meister, A., and Anderson, M. E. (1983) Glutathione. Annu. Rev. Biochem. 52, 711-760
37. Cleland, W. W. (1964) Dithiothreitol, a new protective reagent for SH groups. Biochemistry 3, 480-485
38. Volterra, A., Trotti, D., Tromba, C., Floridi S., and Racagni, G. (1994) Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J. Neurosci. 14, 2924-2932
39. Kanai, Y., Smith, C. P., and Hediger, M. A. (1993) A new family of neurotransmitter transporters: the high-affinity glutamate transporters. FASEB J. 7, 1450-1459
40. Rothstein, J. D., Matin, L., Levey, A. I., Dykes-Hoberg, M., Jin, L., Wu, D., Nash, N., and Kuncl, R. W. (1994) Localization of neuronal and glial glutamate transporters. Neuron 13, 713-725
41. +-dependent glulamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA 89, 10955-10959
42. Pines, G., Danbolt, N. C., Bjoras, M., Zhang, Y., Bendehan, A., Eide, L., Koepsell, H., Storm-Mathisen, J., Seeberg, E., and Kanner, B. I. (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature (London) 360, 464-467
43. Rauen, T., and Kanner, B. I. (1994) Localization of the glutamate transporter GLT-1 in rat and macaque monkey retina. Neurosci. Lett. 169, 137-140
44. Derouiche, A., and Rauen, T. (1995) Coincidence of L-glutamate/L-Aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: Evidence for coupling of GLAST and GS in transmitter clearance. J. Neurosci. Res. 42, 131-143
45. Nicholls, D., and Attwell, D. (1990) The release and uptake of excitatory amino acids. Trends Pharmacol. 11, 462-468
46. Witting, L. A. (1980) Vitamin E and lipid antioxidants in free-radical-initiated reactions. In: Free radicals in Biology (Pryor, W. A., ed) Vol. 4, pp. 295-319, Academic, New York
47. Poeggeler, B., Reiter, R. J., Tan, D.-X., Chen, L.-D., and Manchester, L. C. (1993) Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis. J. Pineal Res. 14, 151-168
48. Pieri, C., Marra, M., Moroni, F., Decchioni, R., and Marcheselli, F. (1994) Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life. Sci. 55, 271-276
49. Hardeland, R., Reiter, R. J., Poeggeler, B., and Tan, D.X. (1993) The significance of the metabolism of the neurohormone melatonin: antioxidative protection and formation of bioactive substances. Neurosci. Biobehav. Res. 17, 347-357
50. Yim, M. B. Chae, H. Z., Rhee S. G. Chock, P. B., and Stadtman E. R. (1994) On the protective mechanism of the thiol-specific antioxidant enzyme against the oxidative damage of biomacromolecules. J. Biol. Chem. 269, 1621-1626
51. Reed, D. J., and Fariss, M. W. (1984) Glutathione depletion and susceptibility. Pharmacol. Rev. 36, 25-33
52. Clark J. A., and Amara, S. G. (1993) Amino acid neurotransmitter transporters: structure, function, and molecular diversity. Bioessays 15, 323-332
53. Casado, M., Zafra, F., Aragón, C., and Giménez, C. (1991) Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures. J. Neurochem. 57, 1185-1190
54. Attwell, D., Miller, B., and Sarantis, M. (1993) Arachidonic acid as a messenger in the Central Nervous System. Semin. Neurosci. 5, 159-169
55. Duarte, C. B., Santos, P. F., Sánchez-Prieto, J., and Carvalho, A.P. (1996) Glutamate release evoked by glutamate receptor agonists in cultured chick retina cells: modulation by arachidonic acid. J. Neurosci. Res. 44, 363-373
56. Chan, P. H., Chen, S. F., and Yu, A. C. H. (1988) Induction of intracellular superoxide radical formation by arachidonic acid and by polyunsaturated fatty acids in primary astrocytic cultures. J. Neurochem. 50, 1004-1007
57. Yang, C.-S., Lin N.-N., Tsai, P.-J., and Kuo, J.-S. (1996) In vivo evidence of hydroxyl radical formation induced by elevation of extracellular glutamate after cerebral ischemia in the cortex of anesthetized rats. Free Rad. Biol. Med. 20, 245-250