Alcohol steatosis and cytotoxicity: The role of cytochrome P4502E1 and autophagy

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1346-1357

  Wu, Defeng ^a   Wang, Xiaodong ^a   Zhou, Richard ^a   Yang, Lili ^a   Cederbaum, Arthur I ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Autophagy; Binge ethanol; CYP2E1; Hepatotoxicity; Oxidative Stress; Steatosis

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; ALCOHOL; BECLIN 1; CLOMETHIAZOLE; CYTOCHROME P450 2E1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN P62; RAPAMYCIN; REACTIVE OXYGEN METABOLITE;

ALCOHOLIC FATTY LIVER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIPID STORAGE; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; AUTOPHAGY; BINGE DRINKING; CELL SURVIVAL; CYTOCHROME P-450 CYP2E1; ETHANOL; FATTY LIVER; GLUTATHIONE; HEP G2 CELLS; HUMANS; LIVER; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; OXIDATIVE STRESS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRIGLYCERIDES;

MUS;

EID: 84865313269     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.005     Document Type: Article

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