Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin

American Journal of Pathology

Volumn 181, Issue 3, 2012, Pages 1017-1033

  Heaton, Joanne H ^a   Wood, Michelle A ^a   Kim, Alex C ^a   Lima, Lorena O ^c   Barlaskar, Ferdous M ^a   Almeida, Madson Q ^c   Fragoso, Maria C B V ^c   Kuick, Rork ^b   Lerario, Antonio M ^c   Simon, Derek P ^a   Soares, Ibere C ^c   Starnes, Elisabeth ^a   Thomas, Dafydd G ^a   Latronico, Ana C ^c   Giordano, Thomas J ^a,b   Hammer, Gary D ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; SOMATOMEDIN B;

ADRENAL CORTEX CARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA CATENIN GENE; CANCER GROWTH; CARCINOGENESIS; CUSHING SYNDROME; GENE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; INSULIN LIKE GROWTH FACTOR 2 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ADRENAL CORTEX HORMONES; ADRENAL CORTEX NEOPLASMS; ANIMALS; BETA CATENIN; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC IMPRINTING; HUMANS; HYPERPLASIA; INSULIN-LIKE GROWTH FACTOR II; LYMPHOID ENHANCER-BINDING FACTOR 1; MICE; MICE, KNOCKOUT; MULTIVARIATE ANALYSIS; MUTATION; NEOPLASM GRADING; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTEIN STABILITY; PROTEIN TRANSPORT; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84865260495     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.05.026     Document Type: Article

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