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Volumn 23, Issue 2, 2009, Pages 261-271

Pathogenesis of adrenocortical cancer

Author keywords

catenin; adrenocortical cancer; IGF II; TP53; trancriptome

Indexed keywords

BETA CATENIN; CORTICOTROPIN RECEPTOR; PROTEIN P53; SOMATOMEDIN B; WNT PROTEIN;

EID: 66549090652     PISSN: 1521690X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beem.2008.10.006     Document Type: Review
Times cited : (43)

References (67)
  • 1
    • 0037418546 scopus 로고    scopus 로고
    • Management of the clinically inapparent adrenal mass ('incidentaloma')
    • Grumbach M.M., Biller B.M., Braunstein G.D., et al. Management of the clinically inapparent adrenal mass ('incidentaloma'). Annals of Internal Medicine 138 (2003) 424-429
    • (2003) Annals of Internal Medicine , vol.138 , pp. 424-429
    • Grumbach, M.M.1    Biller, B.M.2    Braunstein, G.D.3
  • 2
    • 0025248241 scopus 로고
    • Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy
    • Luton J.P., Cerdas S., Billaud L., et al. Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy. New England Journal of Medicine 322 (1990) 1195-1201
    • (1990) New England Journal of Medicine , vol.322 , pp. 1195-1201
    • Luton, J.P.1    Cerdas, S.2    Billaud, L.3
  • 4
    • 33745777816 scopus 로고    scopus 로고
    • Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients
    • Abiven G., Coste J., Groussin L., et al. Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients. Journal of Clinical Endocrinology and Metabolism 91 (2006) 2650-2655
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 2650-2655
    • Abiven, G.1    Coste, J.2    Groussin, L.3
  • 5
    • 34249810952 scopus 로고    scopus 로고
    • Adrenocortical cancer: pathophysiology and clinical management
    • Libe R., Fratticci A., and Bertherat J. Adrenocortical cancer: pathophysiology and clinical management. Endocrine-Related Cancer 14 (2007) 13-28
    • (2007) Endocrine-Related Cancer , vol.14 , pp. 13-28
    • Libe, R.1    Fratticci, A.2    Bertherat, J.3
  • 6
    • 27644431904 scopus 로고    scopus 로고
    • Molecular genetics of adrenocortical tumours, from familial to sporadic diseases
    • Libe R., and Bertherat J. Molecular genetics of adrenocortical tumours, from familial to sporadic diseases. European Journal of Endocrinology 153 (2005) 477-487
    • (2005) European Journal of Endocrinology , vol.153 , pp. 477-487
    • Libe, R.1    Bertherat, J.2
  • 8
    • 0027967028 scopus 로고
    • Clonal composition of human adrenocortical neoplasms
    • Beuschlein F., Reincke M., Karl M., et al. Clonal composition of human adrenocortical neoplasms. Cancer Research 54 (1994) 4927-4932
    • (1994) Cancer Research , vol.54 , pp. 4927-4932
    • Beuschlein, F.1    Reincke, M.2    Karl, M.3
  • 10
    • 0029810445 scopus 로고    scopus 로고
    • Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy
    • Kjellman M., Kallioniemi O.P., Karhu R., et al. Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy. Cancer Research 56 (1996) 4219-4223
    • (1996) Cancer Research , vol.56 , pp. 4219-4223
    • Kjellman, M.1    Kallioniemi, O.P.2    Karhu, R.3
  • 11
    • 0032979047 scopus 로고    scopus 로고
    • Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16
    • Kjellman M., Roshani L., Teh B.T., et al. Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16. Journal of Clinical Endocrinology and Metabolism 84 (1999) 730-735
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , pp. 730-735
    • Kjellman, M.1    Roshani, L.2    Teh, B.T.3
  • 12
    • 0032830530 scopus 로고    scopus 로고
    • Analysis of genomic alterations in sporadic adrenocortical lesions. Gain of chromosome 17 is an early event in adrenocortical tumorigenesis
    • Zhao J., Speel E.J., Muletta-Feurer S., et al. Analysis of genomic alterations in sporadic adrenocortical lesions. Gain of chromosome 17 is an early event in adrenocortical tumorigenesis. American Journal of Pathology 155 (1999) 1039-1045
    • (1999) American Journal of Pathology , vol.155 , pp. 1039-1045
    • Zhao, J.1    Speel, E.J.2    Muletta-Feurer, S.3
  • 13
    • 0034057732 scopus 로고    scopus 로고
    • Adrenocortical carcinoma is characterized by a high frequency of chromosomal gains and high-level amplifications
    • Dohna M., Reincke M., Mincheva A., et al. Adrenocortical carcinoma is characterized by a high frequency of chromosomal gains and high-level amplifications. Genes Chromosomes Cancer 28 (2000) 145-152
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 145-152
    • Dohna, M.1    Reincke, M.2    Mincheva, A.3
  • 14
    • 0035884186 scopus 로고    scopus 로고
    • Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors
    • Gicquel C., Bertagna X., Gaston V., et al. Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors. Cancer Research 61 (2001) 6762-6767
    • (2001) Cancer Research , vol.61 , pp. 6762-6767
    • Gicquel, C.1    Bertagna, X.2    Gaston, V.3
  • 15
    • 0026579237 scopus 로고
    • TP53 tumor suppressor gene: a model for investigating human mutagenesis
    • Caron de Fromentel C., and Soussi T. TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromosomes Cancer 4 (1992) 1-15
    • (1992) Genes Chromosomes Cancer , vol.4 , pp. 1-15
    • Caron de Fromentel, C.1    Soussi, T.2
  • 17
    • 0033601346 scopus 로고    scopus 로고
    • Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
    • Bell D.W., Varley J.M., Szydlo T.E., et al. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 286 (1999) 2528-2531
    • (1999) Science , vol.286 , pp. 2528-2531
    • Bell, D.W.1    Varley, J.M.2    Szydlo, T.E.3
  • 18
    • 0027985697 scopus 로고
    • High frequency of germline p53 mutations in childhood adrenocortical cancer
    • Wagner J., Portwine C., Rabin K., et al. High frequency of germline p53 mutations in childhood adrenocortical cancer. Journal of the National Cancer Institute 86 (1994) 1707-1710
    • (1994) Journal of the National Cancer Institute , vol.86 , pp. 1707-1710
    • Wagner, J.1    Portwine, C.2    Rabin, K.3
  • 19
    • 0033365202 scopus 로고    scopus 로고
    • Are there low-penetrance TP53 Alleles? evidence from childhood adrenocortical tumors
    • Varley J.M., McGown G., Thorncroft M., et al. Are there low-penetrance TP53 Alleles? evidence from childhood adrenocortical tumors. American Journal of Human Genetics 65 (1999) 995-1006
    • (1999) American Journal of Human Genetics , vol.65 , pp. 995-1006
    • Varley, J.M.1    McGown, G.2    Thorncroft, M.3
  • 21
    • 0034750121 scopus 로고    scopus 로고
    • An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors
    • Latronico A.C., Pinto E.M., Domenice S., et al. An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism 86 (2001) 4970-4973
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , pp. 4970-4973
    • Latronico, A.C.1    Pinto, E.M.2    Domenice, S.3
  • 22
    • 0036143771 scopus 로고    scopus 로고
    • A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer
    • DiGiammarino E.L., Lee A.S., Cadwell C., et al. A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer. Nature Structural Biology 9 (2002) 12-16
    • (2002) Nature Structural Biology , vol.9 , pp. 12-16
    • DiGiammarino, E.L.1    Lee, A.S.2    Cadwell, C.3
  • 24
    • 0028177520 scopus 로고
    • p53 mutations in human adrenocortical neoplasms: immunohistochemical and molecular studies
    • Reincke M., Karl M., Travis W.H., et al. p53 mutations in human adrenocortical neoplasms: immunohistochemical and molecular studies. Journal of Clinical Endocrinology and Metabolism 78 (1994) 790-794
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 790-794
    • Reincke, M.1    Karl, M.2    Travis, W.H.3
  • 25
    • 33847415406 scopus 로고    scopus 로고
    • Somatic TP53 mutations are relatively rare among adrenocortical cancers with the frequent 17p13 loss of heterozygosity
    • Libe R., Groussin L., Tissier F., et al. Somatic TP53 mutations are relatively rare among adrenocortical cancers with the frequent 17p13 loss of heterozygosity. Clinical Cancer Research 13 (2007) 844-850
    • (2007) Clinical Cancer Research , vol.13 , pp. 844-850
    • Libe, R.1    Groussin, L.2    Tissier, F.3
  • 27
    • 37549045051 scopus 로고    scopus 로고
    • Loss of heterozygosity of 17p13, with possible involvement of ACADVL and ALOX15B, in the pathogenesis of adrenocortical tumors
    • Soon P.S., Libe R., Benn D.E., et al. Loss of heterozygosity of 17p13, with possible involvement of ACADVL and ALOX15B, in the pathogenesis of adrenocortical tumors. Annals of Surgery 247 (2008) 157-164
    • (2008) Annals of Surgery , vol.247 , pp. 157-164
    • Soon, P.S.1    Libe, R.2    Benn, D.E.3
  • 28
    • 0025967857 scopus 로고
    • Parental imprinting of the mouse insulin-like growth factor II gene
    • DeChiara T.M., Robertson E.J., and Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64 (1991) 849-859
    • (1991) Cell , vol.64 , pp. 849-859
    • DeChiara, T.M.1    Robertson, E.J.2    Efstratiadis, A.3
  • 29
    • 0027442239 scopus 로고
    • Tumour-suppressor activity of H19 RNA
    • Hao Y., Crenshaw T., Moulton T., et al. Tumour-suppressor activity of H19 RNA. Nature 365 (1993) 764-767
    • (1993) Nature , vol.365 , pp. 764-767
    • Hao, Y.1    Crenshaw, T.2    Moulton, T.3
  • 30
    • 0028988159 scopus 로고
    • p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene
    • Matsuoka S., Edwards M.C., Bai C., et al. p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes & Development 9 (1995) 650-662
    • (1995) Genes & Development , vol.9 , pp. 650-662
    • Matsuoka, S.1    Edwards, M.C.2    Bai, C.3
  • 31
    • 0028988158 scopus 로고
    • Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • Lee M.H., Reynisdottir I., and Massague J. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes & Development 9 (1995) 639-649
    • (1995) Genes & Development , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdottir, I.2    Massague, J.3
  • 32
    • 0032589195 scopus 로고    scopus 로고
    • Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlation
    • Lam W.W., Hatada I., Ohishi S., et al. Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlation. Journal of Medical Genetics 36 (1999) 518-523
    • (1999) Journal of Medical Genetics , vol.36 , pp. 518-523
    • Lam, W.W.1    Hatada, I.2    Ohishi, S.3
  • 33
    • 0020534650 scopus 로고
    • The proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections
    • Wiedemann H.R., Burgio G.R., Aldenhoff P., et al. The proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections. European Journal of Pediatrics 140 (1983) 5-12
    • (1983) European Journal of Pediatrics , vol.140 , pp. 5-12
    • Wiedemann, H.R.1    Burgio, G.R.2    Aldenhoff, P.3
  • 34
    • 0042878488 scopus 로고    scopus 로고
    • Late relapse of adrenocortical carcinoma in Beckwith-Wiedemann syndrome. Clinical, endocrinological and genetic aspects
    • Hertel N.T., Carlsen N., Kerndrup G., et al. Late relapse of adrenocortical carcinoma in Beckwith-Wiedemann syndrome. Clinical, endocrinological and genetic aspects. Acta Paediatrica 92 (2003) 439-443
    • (2003) Acta Paediatrica , vol.92 , pp. 439-443
    • Hertel, N.T.1    Carlsen, N.2    Kerndrup, G.3
  • 35
    • 0027412747 scopus 로고
    • Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland
    • Mesiano S., Mellon S.H., and Jaffe R.B. Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland. Journal of Clinical Endocrinology and Metabolism 76 (1993) 968-976
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 968-976
    • Mesiano, S.1    Mellon, S.H.2    Jaffe, R.B.3
  • 36
    • 0028298220 scopus 로고
    • Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors
    • Gicquel C., Bertagna X., Schneid H., et al. Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism 78 (1994) 1444-1453
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 1444-1453
    • Gicquel, C.1    Bertagna, X.2    Schneid, H.3
  • 37
    • 0027370355 scopus 로고
    • Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: high IGF-II expression in functional adrenocortical carcinomas
    • Ilvesmaki V., Kahri A.I., Miettinen P.J., et al. Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: high IGF-II expression in functional adrenocortical carcinomas. Journal of Clinical Endocrinology and Metabolism 77 (1993) 852-858
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.77 , pp. 852-858
    • Ilvesmaki, V.1    Kahri, A.I.2    Miettinen, P.J.3
  • 38
    • 0031784613 scopus 로고    scopus 로고
    • Increased levels of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 are associated with malignancy in sporadic adrenocortical tumors
    • Boulle N., Logie A., Gicquel C., et al. Increased levels of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 are associated with malignancy in sporadic adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism 83 (1998) 1713-1720
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 1713-1720
    • Boulle, N.1    Logie, A.2    Gicquel, C.3
  • 39
    • 0030840738 scopus 로고    scopus 로고
    • Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: study on a series of 82 tumors
    • Gicquel C., Raffin-Sanson M.L., Gaston V., et al. Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: study on a series of 82 tumors. Journal of Clinical Endocrinology and Metabolism 82 (1997) 2559-2565
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 2559-2565
    • Gicquel, C.1    Raffin-Sanson, M.L.2    Gaston, V.3
  • 40
    • 0037331277 scopus 로고    scopus 로고
    • Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis
    • Giordano T.J., Thomas D.G., Kuick R., et al. Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis. American Journal of Pathology 162 (2003) 521-531
    • (2003) American Journal of Pathology , vol.162 , pp. 521-531
    • Giordano, T.J.1    Thomas, D.G.2    Kuick, R.3
  • 41
    • 20144386848 scopus 로고    scopus 로고
    • Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy
    • de Fraipont F., El Atifi M., Cherradi N., et al. Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy. Journal of Clinical Endocrinology and Metabolism 90 (2005) 1819-1829
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , pp. 1819-1829
    • de Fraipont, F.1    El Atifi, M.2    Cherradi, N.3
  • 42
    • 0027285258 scopus 로고
    • Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
    • Ogawa O., Eccles M.R., Szeto J., et al. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature 362 (1993) 749-751
    • (1993) Nature , vol.362 , pp. 749-751
    • Ogawa, O.1    Eccles, M.R.2    Szeto, J.3
  • 43
    • 0027172683 scopus 로고
    • Relaxation of imprinted genes in human cancer
    • Rainier S., Johnson L.A., Dobry C.J., et al. Relaxation of imprinted genes in human cancer. Nature 362 (1993) 747-749
    • (1993) Nature , vol.362 , pp. 747-749
    • Rainier, S.1    Johnson, L.A.2    Dobry, C.J.3
  • 44
    • 0030996260 scopus 로고    scopus 로고
    • Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands
    • Weber M.M., Auernhammer C.J., Kiess W., et al. Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands. European Journal of Endocrinology 136 (1997) 296-303
    • (1997) European Journal of Endocrinology , vol.136 , pp. 296-303
    • Weber, M.M.1    Auernhammer, C.J.2    Kiess, W.3
  • 45
    • 0032789933 scopus 로고    scopus 로고
    • Autocrine role of IGF-II in proliferation of human adrenocortical carcinoma NCI H295R cell line
    • Logie A., Boulle N., Gaston V., et al. Autocrine role of IGF-II in proliferation of human adrenocortical carcinoma NCI H295R cell line. Journal of Molecular Endocrinology 23 (1999) 23-32
    • (1999) Journal of Molecular Endocrinology , vol.23 , pp. 23-32
    • Logie, A.1    Boulle, N.2    Gaston, V.3
  • 46
    • 0035147571 scopus 로고    scopus 로고
    • Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors
    • Boulle N., Baudin E., Gicquel C., et al. Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors. European Journal of Endocrinology 144 (2001) 29-36
    • (2001) European Journal of Endocrinology , vol.144 , pp. 29-36
    • Boulle, N.1    Baudin, E.2    Gicquel, C.3
  • 47
    • 0036964274 scopus 로고    scopus 로고
    • Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors
    • Gao Z.H., Suppola S., Liu J., et al. Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism 87 (2002) 1170-1176
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , pp. 1170-1176
    • Gao, Z.H.1    Suppola, S.2    Liu, J.3
  • 48
    • 0031156782 scopus 로고    scopus 로고
    • Ribonucleic acid expression of the clustered imprinted genes, p57KIP2, insulin-like growth factor II, and H19, in adrenal tumors and cultured adrenal cells
    • Liu J., Kahri A.I., Heikkila P., et al. Ribonucleic acid expression of the clustered imprinted genes, p57KIP2, insulin-like growth factor II, and H19, in adrenal tumors and cultured adrenal cells. Journal of Clinical Endocrinology and Metabolism 82 (1997) 1766-1771
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 1766-1771
    • Liu, J.1    Kahri, A.I.2    Heikkila, P.3
  • 49
    • 50649101532 scopus 로고    scopus 로고
    • Targeted disruption of {beta}-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
    • Kim A.C., Reuter A.L., Zubair M., et al. Targeted disruption of {beta}-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development 135 (2008) 2593-2602
    • (2008) Development , vol.135 , pp. 2593-2602
    • Kim, A.C.1    Reuter, A.L.2    Zubair, M.3
  • 50
    • 0038636318 scopus 로고    scopus 로고
    • Tumor formation by genetic mutations in the components of the Wnt signaling pathway
    • Kikuchi A. Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Science 94 (2003) 225-229
    • (2003) Cancer Science , vol.94 , pp. 225-229
    • Kikuchi, A.1
  • 51
    • 0019467102 scopus 로고
    • Adrenal adenomas in a patient with Gardner's syndrome
    • Naylor E.W., and Gardner E.J. Adrenal adenomas in a patient with Gardner's syndrome. Clinical Genetics 20 (1981) 67-73
    • (1981) Clinical Genetics , vol.20 , pp. 67-73
    • Naylor, E.W.1    Gardner, E.J.2
  • 52
    • 4143091407 scopus 로고    scopus 로고
    • Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli
    • Blaker H., Sutter C., Kadmon M., et al. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli. Genes Chromosomes Cancer 41 (2004) 93-98
    • (2004) Genes Chromosomes Cancer , vol.41 , pp. 93-98
    • Blaker, H.1    Sutter, C.2    Kadmon, M.3
  • 53
    • 24744454197 scopus 로고    scopus 로고
    • Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors
    • Tissier F., Cavard C., Groussin L., et al. Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors. Cancer Research 65 (2005) 7622-7627
    • (2005) Cancer Research , vol.65 , pp. 7622-7627
    • Tissier, F.1    Cavard, C.2    Groussin, L.3
  • 54
    • 38049130282 scopus 로고    scopus 로고
    • Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas
    • Tadjine M., Lampron A., Ouadi L., et al. Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas. Clinical Endocrinology (Oxford) 68 (2008) 264-270
    • (2008) Clinical Endocrinology (Oxford) , vol.68 , pp. 264-270
    • Tadjine, M.1    Lampron, A.2    Ouadi, L.3
  • 55
    • 53749096474 scopus 로고    scopus 로고
    • Wnt/beta-catenin and cAMP/PKA signaling pathways alterations and somatic ss-catenin gene mutations in the progression of adrenocortical tumors
    • S. Gaujoux, F. Tissier, L. Groussin, et al. Wnt/beta-catenin and cAMP/PKA signaling pathways alterations and somatic ss-catenin gene mutations in the progression of adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism 2008; 93: 4135-4140.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 4135-4140
    • Gaujoux, S.1    Tissier, F.2    Groussin, L.3    et al4
  • 56
    • 49649127949 scopus 로고    scopus 로고
    • Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease
    • M. Tadjine, A. Lampron, L. Ouadi, et al. Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease. Clinical Endocrinology (Oxford) 2008; 69: 367-373.
    • (2008) Clinical Endocrinology (Oxford) , vol.69 , pp. 367-373
    • Tadjine, M.1    Lampron, A.2    Ouadi, L.3    et al4
  • 57
    • 49249137734 scopus 로고    scopus 로고
    • The Tcf/{beta}-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells
    • M. Doghman, J. Cazareth and E. Lalli. The Tcf/{beta}-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells. Journal of Clinical Endocrinology and Metabolism 2008; 93: 3222-3225.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 3222-3225
    • Doghman, M.1    Cazareth, J.2    Lalli, E.3
  • 58
    • 0032138226 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia-syndromes of the twentieth century
    • Thakker R.V. Multiple endocrine neoplasia-syndromes of the twentieth century. Journal of Clinical Endocrinology and Metabolism 83 (1998) 2617-2620
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 2617-2620
    • Thakker, R.V.1
  • 59
    • 0034457414 scopus 로고    scopus 로고
    • Complete sequencing and messenger ribonucleic acid expression analysis of the MEN I gene in adrenal cancer
    • Schulte K.M., Mengel M., Heinze M., et al. Complete sequencing and messenger ribonucleic acid expression analysis of the MEN I gene in adrenal cancer. Journal of Clinical Endocrinology and Metabolism 85 (2000) 441-448
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 441-448
    • Schulte, K.M.1    Mengel, M.2    Heinze, M.3
  • 61
    • 0030883247 scopus 로고    scopus 로고
    • Deletion of the adrenocorticotropin receptor gene in human adrenocortical tumors: implications for tumorigenesis
    • Reincke M., Mora P., Beuschlein F., et al. Deletion of the adrenocorticotropin receptor gene in human adrenocortical tumors: implications for tumorigenesis. Journal of Clinical Endocrinology and Metabolism 82 (1997) 3054-3058
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 3054-3058
    • Reincke, M.1    Mora, P.2    Beuschlein, F.3
  • 62
  • 63
    • 0031720976 scopus 로고    scopus 로고
    • Aminoglutethimide suppresses adrenocorticotropin receptor expression in the NCI-h295 adrenocortical tumor cell line
    • Fassnacht M., Beuschlein F., Vay S., et al. Aminoglutethimide suppresses adrenocorticotropin receptor expression in the NCI-h295 adrenocortical tumor cell line. Journal of Endocrinology 159 (1998) 35-42
    • (1998) Journal of Endocrinology , vol.159 , pp. 35-42
    • Fassnacht, M.1    Beuschlein, F.2    Vay, S.3
  • 64
    • 33748302021 scopus 로고    scopus 로고
    • Functional genomics approaches for the study of sporadic adrenal tumor pathogenesis: clinical implications
    • Igaz P., Wiener Z., Szabo P., et al. Functional genomics approaches for the study of sporadic adrenal tumor pathogenesis: clinical implications. Journal of Steroid Biochemistry and Molecular Biology 101 (2006) 87-96
    • (2006) Journal of Steroid Biochemistry and Molecular Biology , vol.101 , pp. 87-96
    • Igaz, P.1    Wiener, Z.2    Szabo, P.3
  • 65
    • 29144437760 scopus 로고    scopus 로고
    • Expression profiling of adrenocortical neoplasms suggests a molecular signature of malignancy
    • Velazquez-Fernandez D., Laurell C., Geli J., et al. Expression profiling of adrenocortical neoplasms suggests a molecular signature of malignancy. Surgery 138 (2005) 1087-1094
    • (2005) Surgery , vol.138 , pp. 1087-1094
    • Velazquez-Fernandez, D.1    Laurell, C.2    Geli, J.3
  • 66
    • 33646043449 scopus 로고    scopus 로고
    • Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors
    • Slater E.P., Diehl S.M., Langer P., et al. Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors. European Journal of Endocrinology 154 (2006) 587-598
    • (2006) European Journal of Endocrinology , vol.154 , pp. 587-598
    • Slater, E.P.1    Diehl, S.M.2    Langer, P.3


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