메뉴 건너뛰기




Volumn , Issue , 2011, Pages 235-262

The insulin-like growth factor system in adrenocortical growth control and carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84865213391     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-77236-3_15     Document Type: Chapter
Times cited : (2)

References (159)
  • 1
    • 3042812480 scopus 로고    scopus 로고
    • Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells
    • Schutt BS et al (2004) Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells. J Mol Endocrinol 32:859-68
    • (2004) J Mol Endocrinol , vol.32 , pp. 859-868
    • Schutt, B.S.1
  • 2
    • 0028890744 scopus 로고
    • The IGFIR: A key to tumor growth?
    • Baserga R (1995) The IGFIR: a key to tumor growth? Cancer Res 555:249-252
    • (1995) Cancer Res , vol.555 , pp. 249-252
    • Baserga, R.1
  • 3
    • 0026576726 scopus 로고
    • Insulin-like growth factors and cancer
    • Macaulay VM (1992) Insulin-like growth factors and cancer. Br J Cancer 65:311-320
    • (1992) Br J Cancer , vol.65 , pp. 311-320
    • Macaulay, V.M.1
  • 4
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • Samani AA et al (2007) The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 28:20-47
    • (2007) Endocr Rev , vol.28 , pp. 20-47
    • Samani, A.A.1
  • 5
    • 0030028186 scopus 로고    scopus 로고
    • The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells
    • Doerr ME, Jones JI (1996) The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells. J Biol Chem 271:2443-7
    • (1996) J Biol Chem , vol.271 , pp. 2443-2447
    • Doerr, M.E.1    Jones, J.I.2
  • 6
    • 0034453098 scopus 로고    scopus 로고
    • The effects of insulin-like growth factors on tumourigenesis and neoplastic growth
    • Khandwala HM et al (2000) The effects of insulin-like growth factors on tumourigenesis and neoplastic growth. Endocrine Reviews 21:215-244
    • (2000) Endocrine Reviews , vol.21 , pp. 215-244
    • Khandwala, H.M.1
  • 7
    • 56749110996 scopus 로고    scopus 로고
    • The type 1 insulin-like growth factor receptor pathway
    • Chitnis MM et al (2008) The type 1 insulin-like growth factor receptor pathway. Clin Cancer Res 14:6364-70
    • (2008) Clin Cancer Res , vol.14 , pp. 6364-6370
    • Chitnis, M.M.1
  • 8
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak MN (2008) Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 8:915-28
    • (2008) Nat Rev Cancer , vol.8 , pp. 915-928
    • Pollak, M.N.1
  • 9
    • 0030926557 scopus 로고    scopus 로고
    • Development and functional biology of the primate fetal adrenal cortex
    • Mesiano S, Jaffe RB (1997) Development and functional biology of the primate fetal adrenal cortex. Endocr Rev 18:378-403
    • (1997) Endocr Rev , vol.18 , pp. 378-403
    • Mesiano, S.1    Jaffe, R.B.2
  • 10
    • 0023920435 scopus 로고
    • Characterization of insulin-like growth factor I and insulin receptors on cultured bovine adrenal fasciculata cells. Role of these peptides on adrenal cell function
    • Penhoat A et al (1988) Characterization of insulin-like growth factor I and insulin receptors on cultured bovine adrenal fasciculata cells. Role of these peptides on adrenal cell function. Endocrinology 122:2518-1526
    • (1988) Endocrinology , vol.122 , pp. 2518-1526
    • Penhoat, A.1
  • 11
    • 84919664711 scopus 로고
    • Identification and characterization of insulin-like growth factor I (IGF1) and IGF2/mannose-6-phosphate (IGF2R) receptors in bovine adrenocortical cells
    • Weber MM et al (1994) Identification and characterization of insulin-like growth factor I (IGF1) and IGF2/mannose-6-phosphate (IGF2R) receptors in bovine adrenocortical cells. Eur J Endocrinol 130:165-170
    • (1994) Eur J Endocrinol , vol.130 , pp. 165-170
    • Weber, M.M.1
  • 12
    • 0028145248 scopus 로고
    • Regulation of adrenal cell-differentiated functions by growth factors
    • Penhoat A et al (1994) Regulation of adrenal cell-differentiated functions by growth factors. Horm Res 42:39-43
    • (1994) Horm Res , vol.42 , pp. 39-43
    • Penhoat, A.1
  • 13
    • 0027412747 scopus 로고
    • Mitogenic action, regulation and localization of insulin-like growth factors in the human fetal adrenal gland
    • Mesiano S et al (1992) Mitogenic action, regulation and localization of insulin-like growth factors in the human fetal adrenal gland. J Clin Endocrinol Metab 76:968-976
    • (1992) J Clin Endocrinol Metab , vol.76 , pp. 968-976
    • Mesiano, S.1
  • 14
    • 84919644847 scopus 로고
    • Insulin-like growth factor-II (IGF2) messenger ribonucleic acid is expressed in steroidogenic cells of the developing ovine adrenal gland: Evidence of an autocrine/paracrine role for IGF2
    • Han VK et al (1992) Insulin-like growth factor-II (IGF2) messenger ribonucleic acid is expressed in steroidogenic cells of the developing ovine adrenal gland: evidence of an autocrine/paracrine role for IGF2. Endocrinology 131:1300-1309
    • (1992) Endocrinology , vol.131 , pp. 1300-1309
    • Han, V.K.1
  • 15
    • 0009751117 scopus 로고
    • Coordinate tropic hormone regulation of mRNAs for insulin-like growth factor II and the cholesterol side-chain-cleavage enzyme, P450scc [corrected], in human steroidogenic tissues
    • Voutilainen R, Miller WL (1987) Coordinate tropic hormone regulation of mRNAs for insulin-like growth factor II and the cholesterol side-chain-cleavage enzyme, P450scc [corrected], in human steroidogenic tissues. Proc Natl Acad Sci USA 84:1590-1594
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1590-1594
    • Voutilainen, R.1    Miller, W.L.2
  • 16
    • 0030918908 scopus 로고    scopus 로고
    • Insulin-like growth factors augment steroid production and expression of steroidogenic enzymes in human fetal adrenal cortical cells: Implications for adrenal androgen regulation
    • Mesiano S et al (1997) Insulin-like growth factors augment steroid production and expression of steroidogenic enzymes in human fetal adrenal cortical cells: Implications for adrenal androgen regulation. J Clin Endocrinol Metab 82:1390-1396
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1390-1396
    • Mesiano, S.1
  • 17
    • 0029818083 scopus 로고    scopus 로고
    • Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin responsiveness in cultured human adrenocortical cells
    • L'Allemand D et al (1996) Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin responsiveness in cultured human adrenocortical cells. J Clin Endocrinol Metab 81:3892-3897
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3892-3897
    • L'Allemand, D.1
  • 18
    • 0026316681 scopus 로고
    • Effects of insulin-like growth factor-I (IGF1) on enzymatic activity in human adrenocortical cells. Interactions with ACTH
    • Pham-Huu-Trung MT et al (1991) Effects of insulin-like growth factor-I (IGF1) on enzymatic activity in human adrenocortical cells. Interactions with ACTH. J Steroid Biochem Molec Biol 39:903-909
    • (1991) J Steroid Biochem Molec Biol , vol.39 , pp. 903-909
    • Pham-Huu-Trung, M.T.1
  • 19
    • 0026522122 scopus 로고
    • Effects of continuous infusion of insulin-like growth factor I and II, alone and in combination with thyroxine or growth hormone, on the neonatal hypophysectomized rat
    • Glasscock GF et al (1992) Effects of continuous infusion of insulin-like growth factor I and II, alone and in combination with thyroxine or growth hormone, on the neonatal hypophysectomized rat. Endocrinology 130:203-210
    • (1992) Endocrinology , vol.130 , pp. 203-210
    • Glasscock, G.F.1
  • 20
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice
    • Rogler CE et al (1994) Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J Biol Chem 260:13779-13784
    • (1994) J Biol Chem , vol.260 , pp. 13779-13784
    • Rogler, C.E.1
  • 21
    • 12244281835 scopus 로고    scopus 로고
    • The adrenal genetic puzzle: How do the fetal and adult pieces differ?
    • Rainey WE et al (2002) The adrenal genetic puzzle: how do the fetal and adult pieces differ? Endocr Res 28:611-622
    • (2002) Endocr Res , vol.28 , pp. 611-622
    • Rainey, W.E.1
  • 22
    • 0023266522 scopus 로고
    • Transplantation of IGF2 secreting tumours in to nude rodents
    • Wilson DM et al (1987) Transplantation of IGF2 secreting tumours in to nude rodents. Endocrinology 120:1896-1901
    • (1987) Endocrinology , vol.120 , pp. 1896-1901
    • Wilson, D.M.1
  • 23
    • 0028130305 scopus 로고
    • Disproportionate growth in mice with IGF2 transgenes
    • Ward A et al (1994) Disproportionate growth in mice with IGF2 transgenes. Proc Natl Acad Sci USA 91:10365-10369
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10365-10369
    • Ward, A.1
  • 24
    • 0031708108 scopus 로고    scopus 로고
    • Regulation of steroidogenesis by insulin-like growth factors (IGFs) in adult human adrenocortical cells: IGF1 and more potently IGF2 preferentially enhance androgen biosynthesis through interaction with the IGFIR and IGF-binding proteins
    • Fottner C et al (1998) Regulation of steroidogenesis by insulin-like growth factors (IGFs) in adult human adrenocortical cells: IGF1 and more potently IGF2 preferentially enhance androgen biosynthesis through interaction with the IGFIR and IGF-binding proteins. J Endocrinol 158:409-417
    • (1998) J Endocrinol , vol.158 , pp. 409-417
    • Fottner, C.1
  • 25
    • 3142757586 scopus 로고    scopus 로고
    • The divergent effect of insulin-like growth factor binding protein (IGFBP-) 1 on the steroidogenic effect of IGF1 and IGF2 in bovine adrenocortical cells is not due to its phosphorylation status
    • Fottner C et al (2007) The divergent effect of insulin-like growth factor binding protein (IGFBP-) 1 on the steroidogenic effect of IGF1 and IGF2 in bovine adrenocortical cells is not due to its phosphorylation status. Growth Hormone and IGF-Research 13:219
    • (2007) Growth Hormone and IGF-research , vol.13 , pp. 219
    • Fottner, C.1
  • 26
    • 0033431824 scopus 로고    scopus 로고
    • The molecular basis of premature adrenarche: A hypothesis
    • Miller WL (1999) The molecular basis of premature adrenarche: a hypothesis. Acta Pediatr Suppl 88:60-66
    • (1999) Acta Pediatr Suppl , vol.88 , pp. 60-66
    • Miller, W.L.1
  • 27
    • 24344486044 scopus 로고    scopus 로고
    • Expression of the IGF system in human adrenal tissues from early infancy to late puberty: Implications for the development of adrenarche
    • Baquedano MS et al (2005) Expression of the IGF System in Human Adrenal Tissues from Early Infancy to Late Puberty: Implications for the Development of Adrenarche. Pediatr Res 58:451-458
    • (2005) Pediatr Res , vol.58 , pp. 451-458
    • Baquedano, M.S.1
  • 28
    • 34347395196 scopus 로고    scopus 로고
    • Independent association between insulin-like growth factor-I and dehydroepiandrosterone sulphate in women in middle adulthood
    • Kasayama S et al (2007) Independent association between insulin-like growth factor-I and dehydroepiandrosterone sulphate in women in middle adulthood. Clin Endocrinol 66:797-802
    • (2007) Clin Endocrinol , vol.66 , pp. 797-802
    • Kasayama, S.1
  • 29
    • 0022647650 scopus 로고
    • Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism
    • Barbieri RL et al (1986) Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism. J Clin Endocrinol Metab 62:904-910
    • (1986) J Clin Endocrinol Metab , vol.62 , pp. 904-910
    • Barbieri, R.L.1
  • 30
    • 35548953244 scopus 로고    scopus 로고
    • Intrafetal insulin-like growth factor-I infusion stimulates adrenal growth but not steroidogenesis in the sheep fetus during late gestation
    • Ross JT et al (2007) Intrafetal insulin-like growth factor-I infusion stimulates adrenal growth but not steroidogenesis in the sheep fetus during late gestation. Endocrinology 148:5424-5432
    • (2007) Endocrinology , vol.148 , pp. 5424-5432
    • Ross, J.T.1
  • 31
    • 0023235340 scopus 로고
    • Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus
    • Han VK et al (1987) Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. Science 236:193-197
    • (1987) Science , vol.236 , pp. 193-197
    • Han, V.K.1
  • 32
    • 0027370355 scopus 로고
    • Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: High IGF2 expression in functional ACCs
    • Ilvesmäki V et al (1993) Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: high IGF2 expression in functional ACCs. J Clin Endocrinol Metab 77:852-8
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 852-858
    • Ilvesmäki, V.1
  • 33
    • 0026099659 scopus 로고
    • Immunoreactivity and receptor expression of insulin-like growth factor I and insulin in human adrenal tumors
    • Kamio T et al (1991) Immunoreactivity and receptor expression of insulin-like growth factor I and insulin in human adrenal tumors. Am J Pathol 138:83-91
    • (1991) Am J Pathol , vol.138 , pp. 83-91
    • Kamio, T.1
  • 34
    • 0024345766 scopus 로고
    • Receptor autoradiographic localization of insulin-like growth factor-I (IGF1) binding sites in human fetal and adult adrenal glands
    • Shigematsu K et al (1989) Receptor autoradiographic localization of insulin-like growth factor-I (IGF1) binding sites in human fetal and adult adrenal glands. Life Sci 45:383-389
    • (1989) Life Sci , vol.45 , pp. 383-389
    • Shigematsu, K.1
  • 35
    • 0023786097 scopus 로고
    • Distribution of receptors for insulin and insulin-like growth factor I (somatomedin C) in the adrenal gland
    • Pillion DJ et al (1988) Distribution of receptors for insulin and insulin-like growth factor I (somatomedin C) in the adrenal gland. Biochem Biophys Res Commun 154:138-145
    • (1988) Biochem Biophys Res Commun , vol.154 , pp. 138-145
    • Pillion, D.J.1
  • 36
    • 0030996260 scopus 로고    scopus 로고
    • Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands
    • Weber MM et al (1997) Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands. Eur J Endocrinol 136:296-303
    • (1997) Eur J Endocrinol , vol.136 , pp. 296-303
    • Weber, M.M.1
  • 37
    • 62449091183 scopus 로고    scopus 로고
    • Expression of the IGF and the aromatase/estrogen receptor systems in human adrenal tissues from early infancy to late puberty: Implications for the development of adrenarche
    • Belgorosky A et al (2009) Expression of the IGF and the aromatase/estrogen receptor systems in human adrenal tissues from early infancy to late puberty: Implications for the development of adrenarche. Rev Endocr Metab Disord 10:51-61
    • (2009) Rev Endocr Metab Disord , vol.10 , pp. 51-61
    • Belgorosky, A.1
  • 38
    • 0002934309 scopus 로고    scopus 로고
    • Adrenocortical and adrenomedullary cells
    • Bidey ES ed, Cambridge University Press, Cambridge
    • Weber MM et al (1998) Adrenocortical and adrenomedullary cells, In: Bidey ES (ed) Endocrine cell culture, Cambridge University Press, Cambridge
    • (1998) Endocrine Cell Culture
    • Weber, M.M.1
  • 39
    • 20744447381 scopus 로고    scopus 로고
    • Fetal adrenal development: Insight gained from adrenal tumors
    • Coulter CL (2005) Fetal adrenal development: insight gained from adrenal tumors, Trends in Endocrinology and Metabolism 16:235-242
    • (2005) Trends in Endocrinology and Metabolism , vol.16 , pp. 235-242
    • Coulter, C.L.1
  • 40
    • 0032789933 scopus 로고    scopus 로고
    • Autocrine role of IGF2 in proliferation of human ACC NCL H295R cell line
    • Logie A et al (1999) Autocrine role of IGF2 in proliferation of human ACC NCL H295R cell line. J Mol Endocrinol 23:23-32
    • (1999) J Mol Endocrinol , vol.23 , pp. 23-32
    • Logie, A.1
  • 41
    • 0038398622 scopus 로고    scopus 로고
    • The Insulin-like growth factor system and cancer
    • LeRoith D, Roberts Jr CT (2003) The Insulin-like growth factor system and cancer. Cancer letters 195:127-137
    • (2003) Cancer Letters , vol.195 , pp. 127-137
    • LeRoith, D.1    Roberts, C.T.2
  • 42
    • 0032928086 scopus 로고    scopus 로고
    • Characterization of Insulin-like growth factor binding proteins (IGFBPs) secreted by bovine adrenocortical cells in primary culture: Regulation by Insulinlike growth factors (IGFs) and adrenocorticotropin (ACTH)
    • Fottner C et al (1999) Characterization of Insulin-like growth factor binding proteins (IGFBPs) secreted by bovine adrenocortical cells in primary culture: Regulation by Insulinlike growth factors (IGFs) and adrenocorticotropin (ACTH). Hormone and Metabolism Res 31:203-208
    • (1999) Hormone and Metabolism Res , vol.31 , pp. 203-208
    • Fottner, C.1
  • 43
    • 0035081074 scopus 로고    scopus 로고
    • Identification and characterization of Insulin-like growth factor binding protein-expression and - Secretion by adult human adrenocortical cells: Differential regulation by IGFs and adrenocorticotropin
    • Fottner C et al (2001) Identification and characterization of Insulin-like growth factor binding protein-expression and - secretion by adult human adrenocortical cells: Differential regulation by IGFs and adrenocorticotropin. J Endocrinol 168:465-474
    • (2001) J Endocrinol , vol.168 , pp. 465-474
    • Fottner, C.1
  • 44
    • 0034097566 scopus 로고    scopus 로고
    • Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis
    • Grimberg A, Cohen P (2000) Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis. J Cell Physiol 183:1-9
    • (2000) J Cell Physiol , vol.183 , pp. 1-9
    • Grimberg, A.1    Cohen, P.2
  • 45
    • 0029156681 scopus 로고
    • Insulin-like growth factor II (IGF2) is more potent than IGF1 in stimulating cortisol secretion from cultured bovine adrenocortical cells: Interactions with the IGFIR and IGF-binding proteins
    • Weber MM et al (1995) Insulin-like growth factor II (IGF2) is more potent than IGF1 in stimulating cortisol secretion from cultured bovine adrenocortical cells: Interactions with the IGFIR and IGF-binding proteins. Endocrinology 136:3714-3720
    • (1995) Endocrinology , vol.136 , pp. 3714-3720
    • Weber, M.M.1
  • 46
    • 0033136406 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein (IGFBP) proteolysis: Occurrence, identification, role and regulation
    • Maile LA, Holly JM (1999) Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation. Growth Horm IGF Res 9:85-95
    • (1999) Growth Horm IGF Res , vol.9 , pp. 85-95
    • Maile, L.A.1    Holly, J.M.2
  • 47
    • 0031110298 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein concentration and post-translational modification in embryological fluid
    • Miell JP et al (1997) Insulin-like growth factor binding protein concentration and post-translational modification in embryological fluid. Mol Hum Reprod 3:343-349
    • (1997) Mol Hum Reprod , vol.3 , pp. 343-349
    • Miell, J.P.1
  • 48
    • 0028263970 scopus 로고
    • Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D
    • Conover CA, De Leon DD (1994) Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D. J Biol Chem 269:7076-7080
    • (1994) J Biol Chem , vol.269 , pp. 7076-7080
    • Conover, C.A.1    De Leon, D.D.2
  • 49
    • 0036847603 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-2 (IGFBP-2) separates hypertrophic and hyperplastic effects of Growth Hormone (GH)/IGF1 excess on adrenocortical cells in vivo
    • Hoeflich A et al (2002) Insulin-like growth factor binding protein-2 (IGFBP-2) separates hypertrophic and hyperplastic effects of Growth Hormone (GH)/IGF1 excess on adrenocortical cells in vivo. FASEB-J 16:1721-1731
    • (2002) FASEB-J , vol.16 , pp. 1721-1731
    • Hoeflich, A.1
  • 50
    • 0033304640 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain
    • Hoeflich A et al (1999) Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain. Endocrinology 140:5488-5496
    • (1999) Endocrinology , vol.140 , pp. 5488-5496
    • Hoeflich, A.1
  • 51
    • 0032980691 scopus 로고    scopus 로고
    • Postnatal overexpression of insulin-like growth factor II in transgenic mice is associated with adrenocortical hyperplasia and enhanced steroidogenesis
    • Weber MM et al (1999) Postnatal overexpression of insulin-like growth factor II in transgenic mice is associated with adrenocortical hyperplasia and enhanced steroidogenesis. Endocrinology 140:1537-1543
    • (1999) Endocrinology , vol.140 , pp. 1537-1543
    • Weber, M.M.1
  • 52
    • 0028982055 scopus 로고
    • Long R3 Insulin-like growth factor I (IGF1) infusion stimulates organ growth but reduces plasma IGF1, IGF2 and IGF binding protein concentrations in the guinea pig
    • Conlon MA et al (1995) Long R3 Insulin-like growth factor I (IGF1) infusion stimulates organ growth but reduces plasma IGF1, IGF2 and IGF binding protein concentrations in the guinea pig. J Endocrinol 146:247-253
    • (1995) J Endocrinol , vol.146 , pp. 247-253
    • Conlon, M.A.1
  • 53
    • 0034483170 scopus 로고    scopus 로고
    • The role of the insulin-like growth factor (IGF) system in adrenocortical tumourigenesis
    • Weber MM et al (2000) The role of the insulin-like growth factor (IGF) system in adrenocortical tumourigenesis. Eur J Clin Invest 30:69-75
    • (2000) Eur J Clin Invest , vol.30 , pp. 69-75
    • Weber, M.M.1
  • 54
    • 0034455570 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 inhibits the maturation of pro-insulin-like growth factor-II (Pro-IGF2) and the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in the human adrenocortical tumor cell line NCI-H295R
    • Boulle N et al (2000) Fibroblast growth factor-2 inhibits the maturation of pro-insulin-like growth factor-II (Pro-IGF2) and the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in the human adrenocortical tumor cell line NCI-H295R. Endocrinology 141:3127-3136
    • (2000) Endocrinology , vol.141 , pp. 3127-3136
    • Boulle, N.1
  • 55
    • 12244302219 scopus 로고    scopus 로고
    • Transcription profiling of benign and malignant adrenal tumors by cDNA macro-array analysis
    • De Fraipont F et al (2002) Transcription profiling of benign and malignant adrenal tumors by cDNA macro-array analysis. Endocr Res 28:785-786
    • (2002) Endocr Res , vol.28 , pp. 785-786
    • De Fraipont, F.1
  • 56
    • 0030890465 scopus 로고    scopus 로고
    • Biological characteristics of ACC: A study of p53, IGF, EGF-r, Ki-67 and PCNA in 17 ACCs
    • Edgren M et al (1997) Biological characteristics of ACC: a study of p53, IGF, EGF-r, Ki-67 and PCNA in 17 ACCs. Anticancer Res 17:1303-1310
    • (1997) Anticancer Res , vol.17 , pp. 1303-1310
    • Edgren, M.1
  • 57
    • 0026834147 scopus 로고
    • Abnormalities of insulin-like growth factor (IGF1 and IGF2) genes in human tumor tissue
    • Schneid H et al (1992) Abnormalities of insulin-like growth factor (IGF1 and IGF2) genes in human tumor tissue. Growth Regulation 2:45-54
    • (1992) Growth Regulation , vol.2 , pp. 45-54
    • Schneid, H.1
  • 58
    • 0031784613 scopus 로고    scopus 로고
    • Increased levels of insulin-like growth factor II (IGF2) and IGF-Binding Protein-2 are associated with malignancy in sporadic adrenocortical tumors
    • Boulle N et al (1998) Increased levels of insulin-like growth factor II (IGF2) and IGF-Binding Protein-2 are associated with malignancy in sporadic adrenocortical tumors. J Clin Endocrinol Metab 83:1713-1720
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1713-1720
    • Boulle, N.1
  • 59
    • 0028298220 scopus 로고
    • Rearrangements at the 11p15 locus and overexpression of insulinlike growth factor-II gene in sporadic adrenocortical tumors
    • Gicquel C et al (1994) Rearrangements at the 11p15 locus and overexpression of insulinlike growth factor-II gene in sporadic adrenocortical tumors. J Clin Endocrinol Metab 78:1444-1453
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1444-1453
    • Gicquel, C.1
  • 60
    • 0030840738 scopus 로고    scopus 로고
    • Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: Study on a series of 82 tumors
    • Gicquel C et al (1997) Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: Study on a series of 82 tumors. J Clin Endocrinol Metab 82:2559-2565
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2559-2565
    • Gicquel, C.1
  • 61
    • 0035884186 scopus 로고    scopus 로고
    • Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors
    • Gicquel C et al (2001) Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors. Cancer Res 61:6762-6767
    • (2001) Cancer Res , vol.61 , pp. 6762-6767
    • Gicquel, C.1
  • 62
    • 0037331277 scopus 로고    scopus 로고
    • Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis
    • Giordano TJ et al (2003) Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis. Am J Pathol 162:521-531
    • (2003) Am J Pathol , vol.162 , pp. 521-531
    • Giordano, T.J.1
  • 63
    • 18344376533 scopus 로고    scopus 로고
    • Pathological features and expression of insulin-like growth factor-2 in adrenocortical neoplasms
    • Erickson LA et al (2001) Pathological features and expression of insulin-like growth factor-2 in adrenocortical neoplasms. Endocr Pathol 12:429-435
    • (2001) Endocr Pathol , vol.12 , pp. 429-435
    • Erickson, L.A.1
  • 64
    • 0034457110 scopus 로고    scopus 로고
    • Pediatric adrenocortical tumors: Molecular events leading to Insulinlike growth factor II gene overexpression
    • Wilkin F et al (2000) Pediatric adrenocortical tumors: molecular events leading to Insulinlike growth factor II gene overexpression. J Clin Endocrinol Metab 85:2048-2056
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2048-2056
    • Wilkin, F.1
  • 65
    • 51649083560 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors
    • Almeida MQ et al (2008) Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors. J Clin Endocrinol Metab 93:3524-3531
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3524-3531
    • Almeida, M.Q.1
  • 66
    • 20144386848 scopus 로고    scopus 로고
    • Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy
    • De Fraipont F et al (2005) Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy. J Clin Endocrinol Metab 90:1819-1829
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1819-1829
    • De Fraipont, F.1
  • 67
    • 33846683317 scopus 로고    scopus 로고
    • Gene expression profiling of childhood adrenocortical tumors
    • West AN et al (2007) Gene expression profiling of childhood adrenocortical tumors. Cancer Res 67:600-608
    • (2007) Cancer Res , vol.67 , pp. 600-608
    • West, A.N.1
  • 68
    • 33646043449 scopus 로고    scopus 로고
    • Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors
    • Slater EP et al (2006) Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors. Eur J Endocrinol 154:587-598
    • (2006) Eur J Endocrinol , vol.154 , pp. 587-598
    • Slater, E.P.1
  • 69
    • 61449137784 scopus 로고    scopus 로고
    • Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival
    • De Reyniès A et al (2009) Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. J Clin Oncol 27:1108-1115
    • (2009) J Clin Oncol , vol.27 , pp. 1108-1115
    • De Reyniès, A.1
  • 70
    • 59449098488 scopus 로고    scopus 로고
    • Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling
    • Giordano TJ et al (2009) Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling. Clin Cancer Res 15:668-676
    • (2009) Clin Cancer Res , vol.15 , pp. 668-676
    • Giordano, T.J.1
  • 71
    • 29144437760 scopus 로고    scopus 로고
    • Expression profiling of adrenocortical neoplasms suggests a molecular signature of malignancy
    • Velázquez-Fernández D et al (2005) Expression profiling of adrenocortical neoplasms suggests a molecular signature of malignancy. Surgery 138:1087-1094
    • (2005) Surgery , vol.138 , pp. 1087-1094
    • Velázquez-Fernández, D.1
  • 72
    • 58149381997 scopus 로고    scopus 로고
    • Preclinical targeting of the type I insulin-like growth factor receptor in ACC
    • Barlaskar FM et al (2009) Preclinical targeting of the type I insulin-like growth factor receptor in ACC. J Clin Endocrinol Metab 94:204-212
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 204-212
    • Barlaskar, F.M.1
  • 73
    • 0034745791 scopus 로고    scopus 로고
    • Loss of heterozygosity at the mannose-6-phosphate/insulin-like growth factor II receptor locus: A frequent but late event in adrenocortical tumorigenesis
    • Leboulleux S et al (2001) Loss of heterozygosity at the mannose-6-phosphate/insulin-like growth factor II receptor locus: a frequent but late event in adrenocortical tumorigenesis. Eur J Endocrinol 144:163-168
    • (2001) Eur J Endocrinol , vol.144 , pp. 163-168
    • Leboulleux, S.1
  • 74
    • 0035147571 scopus 로고    scopus 로고
    • Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors
    • Boulle N et al (2001) Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors. Eur J Endocrinol 144:29-36
    • (2001) Eur J Endocrinol , vol.144 , pp. 29-36
    • Boulle, N.1
  • 75
    • 0031776531 scopus 로고    scopus 로고
    • Immunodetection of Insulin-like growth factor I (IGF1) in normal and pathological adrenocortical tissue
    • Faical S et al (1998) Immunodetection of Insulin-like growth factor I (IGF1) in normal and pathological adrenocortical tissue. Endocr Pathol 9:63-70
    • (1998) Endocr Pathol , vol.9 , pp. 63-70
    • Faical, S.1
  • 76
    • 0029115129 scopus 로고
    • Recent advances in the pathogenesis of adrenocortical tumours
    • Gicquel C et al (1995) Recent advances in the pathogenesis of adrenocortical tumours. Eur J Endocrinol 133:133-144
    • (1995) Eur J Endocrinol , vol.133 , pp. 133-144
    • Gicquel, C.1
  • 77
    • 52249109610 scopus 로고    scopus 로고
    • Identification of biomarkers of ACC using genomewide gene expression profiling
    • Fernandez-Ranvier GG et al (2008) Identification of biomarkers of ACC using genomewide gene expression profiling. Arch Surg 143:841-846
    • (2008) Arch Surg , vol.143 , pp. 841-846
    • Fernandez-Ranvier, G.G.1
  • 78
    • 51149100337 scopus 로고    scopus 로고
    • High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression are not related to clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation
    • Rosati R et al (2008) High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression are not related to clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation. Cancer Genet Cytogenet 186:19-24
    • (2008) Cancer Genet Cytogenet , vol.186 , pp. 19-24
    • Rosati, R.1
  • 79
    • 33846089053 scopus 로고    scopus 로고
    • Prognostic parameters of metastatic ACC
    • Assié G et al (2007) Prognostic Parameters of Metastatic ACC. J Clin Endocrinol Metab 92:148-154
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 148-154
    • Assié, G.1
  • 80
    • 0028804071 scopus 로고
    • M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
    • De Souza AT et al (1995) M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nature Genet. 11:447-449
    • (1995) Nature Genet , vol.11 , pp. 447-449
    • De Souza, A.T.1
  • 81
    • 0025181755 scopus 로고
    • Relative abundance and molecular size of immunoreactive insulin-like growth factors I and II in human fetal tissues
    • Hill D. Relative abundance and molecular size of immunoreactive insulin-like growth factors I and II in human fetal tissues (1990) Early Hum Dev 21:49-58
    • (1990) Early Hum Dev , vol.21 , pp. 49-58
    • Hill, D.1
  • 82
    • 0027412747 scopus 로고
    • Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland
    • Mesiano S et al (1993) Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland. J Clin Endocrinol Metab 76:968-976
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 968-976
    • Mesiano, S.1
  • 83
    • 0028061877 scopus 로고
    • Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: Endocrine changes and effects on body and organ growth
    • Wolf E et al (1994) Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: endocrine changes and effects on body and organ growth. Endocrinology 135:1877-1886
    • (1994) Endocrinology , vol.135 , pp. 1877-1886
    • Wolf, E.1
  • 84
    • 0031150018 scopus 로고    scopus 로고
    • Actions and interactions of growth hormone and insulinlike growth factor-II: Body and organ growth of transgenic mice
    • Blackburn A et al (1997) Actions and interactions of growth hormone and insulinlike growth factor-II: body and organ growth of transgenic mice. Transgenic Res 6:213-222
    • (1997) Transgenic Res , vol.6 , pp. 213-222
    • Blackburn, A.1
  • 85
    • 0028966822 scopus 로고
    • Overexpression of human insulin-like growth factor-II in transgenic mice causes increased weight of the thymus
    • van Buul-Offers SC et al (1995) Overexpression of human insulin-like growth factor-II in transgenic mice causes increased weight of the thymus. J Endocrinol 144:91-502
    • (1995) J Endocrinol , vol.144 , pp. 91-502
    • Van Buul-Offers, S.C.1
  • 86
    • 0037846124 scopus 로고    scopus 로고
    • Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells
    • Zaina S et al (2003) Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells. Endocrinology 144:2695-2703
    • (2003) Endocrinology , vol.144 , pp. 2695-2703
    • Zaina, S.1
  • 87
    • 0026016354 scopus 로고
    • Elevated corticosterone levels in transgenic mice expressing human or bovine growth hormone genes
    • Cecim M et al (1991) Elevated corticosterone levels in transgenic mice expressing human or bovine growth hormone genes. Neuroendocrinology 53:313-316
    • (1991) Neuroendocrinology , vol.53 , pp. 313-316
    • Cecim, M.1
  • 88
    • 0032453535 scopus 로고    scopus 로고
    • What is the function of IGF2 in postnatal life? Answers from transgenic mouse models
    • Wolf E et al (1998) What is the function of IGF2 in postnatal life? Answers from transgenic mouse models. Growth Horm IGF Res 8:185-193
    • (1998) Growth Horm IGF Res , vol.8 , pp. 185-193
    • Wolf, E.1
  • 89
    • 27644431904 scopus 로고    scopus 로고
    • Molecular genetics of adrenocortical tumours, from familial to sporadic disease
    • Libé R, Bertherat J (2005) Molecular genetics of adrenocortical tumours, from familial to sporadic disease. Eur J Endocrinol 153:477-487
    • (2005) Eur J Endocrinol , vol.153 , pp. 477-487
    • Libé, R.1    Bertherat, J.2
  • 90
    • 0028887454 scopus 로고
    • H19 and insulin-like growth factor-II gene expression in adrenal tumors and cultured adrenal cells
    • Liu J et al (1995) H19 and insulin-like growth factor-II gene expression in adrenal tumors and cultured adrenal cells. J Clin Endocrinol Metab 80:492-496
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 492-496
    • Liu, J.1
  • 91
    • 0029948828 scopus 로고    scopus 로고
    • Involvement of IGF2 in human cancer
    • Toretsky JA, Helman LJ (1996) Involvement of IGF2 in human cancer. J Endocrinol 149:367-372
    • (1996) J Endocrinol , vol.149 , pp. 367-372
    • Toretsky, J.A.1    Helman, L.J.2
  • 92
    • 0036298023 scopus 로고    scopus 로고
    • Signaling pathways in ACC
    • Kirschner LS (2002) Signaling pathways in ACC. Ann N Y Acad Sci 58:222-239
    • (2002) Ann N Y Acad Sci , vol.58 , pp. 222-239
    • Kirschner, L.S.1
  • 93
    • 0034455462 scopus 로고    scopus 로고
    • High expression of cyclin E and G1 CDK and loss of function of p57KIP2 are involved in proliferation of malignant sporadic adrenocortical tumors
    • Bourcigaux N et al (2000) High expression of cyclin E and G1 CDK and loss of function of p57KIP2 are involved in proliferation of malignant sporadic adrenocortical tumors. J Clin Endocrinol Metab 85:322-330
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 322-330
    • Bourcigaux, N.1
  • 94
    • 0032486384 scopus 로고    scopus 로고
    • The INS 5' variable number of tandem repeats is associated with IGF2 expression in humans
    • Paquette J et al (1998) The INS 5' variable number of tandem repeats is associated with IGF2 expression in humans. J Biol Chem 273:14158-14164
    • (1998) J Biol Chem , vol.273 , pp. 14158-14164
    • Paquette, J.1
  • 95
    • 0024558302 scopus 로고
    • Genetic changes in human ACCs
    • Yano T et al (1989) Genetic changes in human ACCs. J Natl Cancer Inst 81:518-523
    • (1989) J Natl Cancer Inst , vol.81 , pp. 518-523
    • Yano, T.1
  • 96
    • 0027231511 scopus 로고
    • Parental allele specific methylation of the human insulin-like growth factor-II gene and Beckwith Wiedemann syndrome
    • Schneid H et al (1993) Parental allele specific methylation of the human insulin-like growth factor-II gene and Beckwith Wiedemann syndrome. J Med Genet 30:353-362
    • (1993) J Med Genet , vol.30 , pp. 353-362
    • Schneid, H.1
  • 97
    • 0034890095 scopus 로고    scopus 로고
    • Altered expression of novH is associated with human adrenocortical tumorigenesis
    • Martinerie C et al (2001) Altered expression of novH is associated with human adrenocortical tumorigenesis. J Clin Endocrinol Metab 86:3929-3940
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3929-3940
    • Martinerie, C.1
  • 98
    • 0037244913 scopus 로고    scopus 로고
    • Characterization of human NOV in biological fluids: An enzyme immunoassay for the quantification of human NOV in sera from patients with diseases of the adrenal gland and of the nervous system
    • Thibout H et al (2003) Characterization of human NOV in biological fluids: an enzyme immunoassay for the quantification of human NOV in sera from patients with diseases of the adrenal gland and of the nervous system. J Clin Endocrinol Metab 88:327-336
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 327-336
    • Thibout, H.1
  • 99
    • 0029014425 scopus 로고
    • P53 activates expression of HIC-1, a new candidate tumor suppressor gene on 17p13.3
    • Makos Wales B et al (1995) p53 activates expression of HIC-1, a new candidate tumor suppressor gene on 17p13.3. Nat Med 1:570-582
    • (1995) Nat Med , vol.1 , pp. 570-582
    • Makos Wales, B.1
  • 100
    • 0031196766 scopus 로고    scopus 로고
    • The p53/IGF-1 receptor axis in the regulation of programmed cell death
    • Neuberg M et al (1997) The p53/IGF-1 receptor axis in the regulation of programmed cell death. Endocrine 7:107-9
    • (1997) Endocrine , vol.7 , pp. 107-109
    • Neuberg, M.1
  • 101
    • 0033911567 scopus 로고    scopus 로고
    • New concepts in regulation and function of the insulin-like growth factors: Implications for understanding normal growth and neoplasia
    • Werner H, Le Roith D (2000) New concepts in regulation and function of the insulin-like growth factors: implications for understanding normal growth and neoplasia. Cell Mol Life Sci. 57:932-42
    • (2000) Cell Mol Life Sci , vol.57 , pp. 932-942
    • Werner, H.1    Le Roith, D.2
  • 102
    • 0033808766 scopus 로고    scopus 로고
    • Regulation of the insulin-like growth factor-I receptor gene by oncogenes and antioncogenes: Implications in human cancer
    • Werner H et al (2000) Regulation of the insulin-like growth factor-I receptor gene by oncogenes and antioncogenes: implications in human cancer. Mol Genet Metab 71:315-20
    • (2000) Mol Genet Metab , vol.71 , pp. 315-320
    • Werner, H.1
  • 103
    • 0034665348 scopus 로고    scopus 로고
    • Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: Functional impact
    • Girnita L et al (2000) Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53:functional impact. Cancer Res 60:5278-5283
    • (2000) Cancer Res , vol.60 , pp. 5278-5283
    • Girnita, L.1
  • 104
    • 0029757120 scopus 로고    scopus 로고
    • Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
    • Werner H et al (1996) Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci USA 93:8318-8323
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8318-8323
    • Werner, H.1
  • 105
    • 0028177520 scopus 로고
    • P53 mutations in human adrenocortical neoplasms: Immunohistochemical and molecular studies
    • Reincke M et al (1994) p53 mutations in human adrenocortical neoplasms: immunohistochemical and molecular studies. J Clin Endocrinol Metab 78:790-796
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 790-796
    • Reincke, M.1
  • 106
    • 0030055088 scopus 로고    scopus 로고
    • Coordinate expression of insulin-like growth factor II (IGF2) and IGF2/mannose-6-phosphate receptor mRNA during differentiation of human colon carcinoma cells (caco-2)
    • Hoeflich A et al (1996) Coordinate expression of insulin-like growth factor II (IGF2) and IGF2/mannose-6-phosphate receptor mRNA during differentiation of human colon carcinoma cells (caco-2). Eur J Endocrinol 135:49-59
    • (1996) Eur J Endocrinol , vol.135 , pp. 49-59
    • Hoeflich, A.1
  • 107
    • 0037110602 scopus 로고    scopus 로고
    • Overexpression of the insulin-like growth factor I receptor in human colon carcinomas
    • Weber MM et al (2002) Overexpression of the insulin-like growth factor I receptor in human colon carcinomas. Cancer 95:2086-2095
    • (2002) Cancer , vol.95 , pp. 2086-2095
    • Weber, M.M.1
  • 108
    • 0029119731 scopus 로고
    • Insulin-like growth factor I receptor. Its role in cell proliferation, apoptosis, and tumourigenicity
    • Rubin R, Baserga R (1995) Insulin-like growth factor I receptor. Its role in cell proliferation, apoptosis, and tumourigenicity. Lab Invest 73:311-331
    • (1995) Lab Invest , vol.73 , pp. 311-331
    • Rubin, R.1    Baserga, R.2
  • 109
    • 0029738916 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis
    • Singleton JR et al (1996) Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis. Cancer Res 56:4522-4529
    • (1996) Cancer Res , vol.56 , pp. 4522-4529
    • Singleton, J.R.1
  • 110
    • 0028884799 scopus 로고
    • Insulin-like growth factor II in the pathogenesis of human neuroblastoma
    • Sullivan KA et al (1995) Insulin-like growth factor II in the pathogenesis of human neuroblastoma. Am J Pathol 147:1790-1798
    • (1995) Am J Pathol , vol.147 , pp. 1790-1798
    • Sullivan, K.A.1
  • 111
    • 0031046959 scopus 로고    scopus 로고
    • Role of insulin-like growth factor binding protein-2 and its limited proteolysis in neuroblastoma cell proliferation: Modulation by transforming growth factorbeta and retinoic acid
    • Menouny M et al (1997) Role of insulin-like growth factor binding protein-2 and its limited proteolysis in neuroblastoma cell proliferation: modulation by transforming growth factorbeta and retinoic acid. Endocrinology 138:683-690
    • (1997) Endocrinology , vol.138 , pp. 683-690
    • Menouny, M.1
  • 112
    • 0025052987 scopus 로고
    • Insulin-like growth factor II: Possible local growth factor in pheochromocytoma
    • Gelato MC, Vassalotti J (1990) Insulin-like growth factor II: possible local growth factor in pheochromocytoma. J Clin Endocrinol and Metabol 7:1168-1174
    • (1990) J Clin Endocrinol and Metabol , vol.7 , pp. 1168-1174
    • Gelato, M.C.1    Vassalotti, J.2
  • 113
    • 0023155425 scopus 로고
    • Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: Expression at the mRNA and protein level
    • Haselbacher GK et al (1987) Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level. PNAS 84:1104-1106
    • (1987) PNAS , vol.84 , pp. 1104-1106
    • Haselbacher, G.K.1
  • 114
    • 33646149647 scopus 로고    scopus 로고
    • Overexpression of the insulin-like growth factor I receptor on human pheochromocytomas
    • Fottner C et al (2006) Overexpression of the insulin-like growth factor I receptor on human pheochromocytomas. J Mol Endocrinol 36:279-287
    • (2006) J Mol Endocrinol , vol.36 , pp. 279-287
    • Fottner, C.1
  • 115
    • 0347664057 scopus 로고    scopus 로고
    • IGFIR regulates lifespan and resistance to oxidative stress in mice
    • Holzenberger M et al (2003) IGFIR regulates lifespan and resistance to oxidative stress in mice. Nature 421:182-187
    • (2003) Nature , vol.421 , pp. 182-187
    • Holzenberger, M.1
  • 116
    • 0037426828 scopus 로고    scopus 로고
    • Cost-free longevity in mice?
    • Lithgow G, Gill MS (2003) Cost-free longevity in mice? Nature 421:125-127
    • (2003) Nature , vol.421 , pp. 125-127
    • Lithgow, G.1    Gill, M.S.2
  • 117
    • 0024419322 scopus 로고
    • Characterization of insulin-like growth factor-I receptors in PC12 pheochromocytoma cells and bovine adrenal medulla
    • Dahmer MK et al (1989) Characterization of insulin-like growth factor-I receptors in PC12 pheochromocytoma cells and bovine adrenal medulla. J Neurochem 53:1036-1042
    • (1989) J Neurochem , vol.53 , pp. 1036-1042
    • Dahmer, M.K.1
  • 118
    • 0023890103 scopus 로고
    • Insulin and insulin-like growth factors stimulate deoxyribonucleic acid synthesis in PC12 pheochromocytoma cells
    • Dahmer MK, Perlman RL (1988) Insulin and insulin-like growth factors stimulate deoxyribonucleic acid synthesis in PC12 pheochromocytoma cells. Endocrinology 22:2109-2113
    • (1988) Endocrinology , vol.22 , pp. 2109-2113
    • Dahmer, M.K.1    Perlman, R.L.2
  • 119
    • 0023765080 scopus 로고
    • Insulin-like growth factors are mitogens for rat pheochromocytoma PC 12 cells
    • Nielsen FC, Gammeltoft S (1988) Insulin-like growth factors are mitogens for rat pheochromocytoma PC 12 cells. Biochem Biophys Res Commun 154:1018-1023
    • (1988) Biochem Biophys Res Commun , vol.154 , pp. 1018-1023
    • Nielsen, F.C.1    Gammeltoft, S.2
  • 120
    • 0036186637 scopus 로고    scopus 로고
    • Characteristics of binding of insulin-like growth factor (IGF)-I and IGF2 analogues to the type 1 IGF receptor determined by BIAcore analysis
    • Forbes BE et al (2002) Characteristics of binding of insulin-like growth factor (IGF)-I and IGF2 analogues to the type 1 IGF receptor determined by BIAcore analysis. Eur J Biochem 269:961-968
    • (2002) Eur J Biochem , vol.269 , pp. 961-968
    • Forbes, B.E.1
  • 121
    • 0030803878 scopus 로고    scopus 로고
    • Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes
    • Foncea R et al (1997) Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes. J Biol Chem 272:19115-9124
    • (1997) J Biol Chem , vol.272 , pp. 19115-19124
    • Foncea, R.1
  • 122
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G et al (1997) Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol 17:1595-1606
    • (1997) Mol Cell Biol , vol.17 , pp. 1595-1606
    • Kulik, G.1
  • 123
    • 0033571113 scopus 로고    scopus 로고
    • Decreased insulin-like growth factor-II/mannose-6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells
    • O'Gorman DB et al (1999) Decreased insulin-like growth factor-II/mannose-6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells. Cancer Res 59:5692-5694
    • (1999) Cancer Res , vol.59 , pp. 5692-5694
    • O'Gorman, D.B.1
  • 124
    • 0033566056 scopus 로고    scopus 로고
    • Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells
    • Souza RF et al (1999) Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells. Oncogene 18:4063-4068
    • (1999) Oncogene , vol.18 , pp. 4063-4068
    • Souza, R.F.1
  • 125
    • 0028575985 scopus 로고
    • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
    • Lau MM et al (1994) Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes and Development 8:2953-2963
    • (1994) Genes and Development , vol.8 , pp. 2953-2963
    • Lau, M.M.1
  • 126
    • 0030221121 scopus 로고    scopus 로고
    • Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds
    • Ludwig T et al (1996) Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Developmental Biology 177:517-535
    • (1996) Developmental Biology , vol.177 , pp. 517-535
    • Ludwig, T.1
  • 127
    • 0027999284 scopus 로고
    • Regulation of embryonic growth and lysosomal targeting by the imprinted IGF 2/Mpr gene
    • Wang Z et al (1994) Regulation of embryonic growth and lysosomal targeting by the imprinted IGF 2/Mpr gene. Nature 372:464-467
    • (1994) Nature , vol.372 , pp. 464-467
    • Wang, Z.1
  • 128
    • 0029934868 scopus 로고    scopus 로고
    • M6P/IGF2 receptor: A candidate breast tumor suppressor gene
    • Hankins GR et al (1996) M6P/IGF2 receptor: a candidate breast tumor suppressor gene. Oncogene 12:2003-2009
    • (1996) Oncogene , vol.12 , pp. 2003-2009
    • Hankins, G.R.1
  • 129
    • 0031964262 scopus 로고    scopus 로고
    • The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene
    • Oates AJ et al (1998) The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene. Breast Cancer Res Treat 47:269-281
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 269-281
    • Oates, A.J.1
  • 130
    • 0032847563 scopus 로고    scopus 로고
    • Genetic aspects of hepatocellular carcinogenesis
    • Ozturk M (1999) Genetic aspects of hepatocellular carcinogenesis. Seminars in Liver Disease 19:235-242
    • (1999) Seminars in Liver Disease , vol.19 , pp. 235-242
    • Ozturk, M.1
  • 131
    • 2542582263 scopus 로고    scopus 로고
    • The role of the M6P/IGF2 receptor in cancer: Tumor suppression or garbage disposal?
    • Scott CD, Firth SM (2004) The role of the M6P/IGF2 receptor in cancer: tumor suppression or garbage disposal? Horm Metab Res 36, 261-71
    • (2004) Horm Metab Res , vol.36 , pp. 261-271
    • Scott, C.D.1    Firth, S.M.2
  • 132
    • 0030889737 scopus 로고    scopus 로고
    • Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor
    • Xu Y et al (1997) Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor. Oncogene 14:1041-1046
    • (1997) Oncogene , vol.14 , pp. 1041-1046
    • Xu, Y.1
  • 133
    • 0027484999 scopus 로고
    • Insulin-like growth factor binding proteins in the human adrenal gland
    • Ilvesmäki V et al (1992) Insulin-like growth factor binding proteins in the human adrenal gland. Mol Cell Endocrinol 97:71-79
    • (1992) Mol Cell Endocrinol , vol.97 , pp. 71-79
    • Ilvesmäki, V.1
  • 134
    • 0034455581 scopus 로고    scopus 로고
    • Establishment and characterization of a human ACC xenograft model
    • Logie A et al (2000) Establishment and characterization of a human ACC xenograft model. Endocrinology 141:3165-3171
    • (2000) Endocrinology , vol.141 , pp. 3165-3171
    • Logie, A.1
  • 135
    • 0024916155 scopus 로고
    • Binding proteins for the insulin-like growth factors: Structure, regulation and function
    • Baxter RC, Martin JL (1989) Binding proteins for the insulin-like growth factors: structure, regulation and function. Prog Growth Factor Research 1:49-68
    • (1989) Prog Growth Factor Research , vol.1 , pp. 49-68
    • Baxter, R.C.1    Martin, J.L.2
  • 136
    • 33750061624 scopus 로고    scopus 로고
    • The role of Insulin-like growth factor binding proteins
    • Holly J, Perks C (2006) The role of Insulin-like growth factor binding proteins. Neuroendocrinology 83:154-160
    • (2006) Neuroendocrinology , vol.83 , pp. 154-160
    • Holly, J.1    Perks, C.2
  • 137
    • 3042781558 scopus 로고    scopus 로고
    • Insulin-like growth factors and neoplasia
    • Pollak MN (2004) Insulin-like growth factors and neoplasia. Nat Rev Cancer 4:505-18
    • (2004) Nat Rev Cancer , vol.4 , pp. 505-518
    • Pollak, M.N.1
  • 138
    • 53349110616 scopus 로고    scopus 로고
    • Insulin-like growth factors and cancer
    • Pollak MN et al (2004) Insulin-like growth factors and cancer. Nat Rev Cancer 14:277-286
    • (2004) Nat Rev Cancer , vol.14 , pp. 277-286
    • Pollak, M.N.1
  • 139
    • 0035893392 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 2 in tumorigenesis: Protector or promoter?
    • Hoeflich A et al (2001) Insulin-like growth factor binding protein 2 in tumorigenesis: protector or promoter? Cancer Res 61:8601-8610
    • (2001) Cancer Res , vol.61 , pp. 8601-8610
    • Hoeflich, A.1
  • 140
    • 0034652746 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-binding protein 2 results in increased tumorigenic potential in Y-1 adrenocortical tumor cells
    • Hoeflich A et al (2000) Overexpression of insulin-like growth factor-binding protein 2 results in increased tumorigenic potential in Y-1 adrenocortical tumor cells. Cancer Res 60:834-838
    • (2000) Cancer Res , vol.60 , pp. 834-838
    • Hoeflich, A.1
  • 141
    • 34047172992 scopus 로고    scopus 로고
    • Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A
    • Shi Z et al (2007) Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A. Growth Horm IGF Res 17:113-121
    • (2007) Growth Horm IGF Res , vol.17 , pp. 113-121
    • Shi, Z.1
  • 142
    • 0023222947 scopus 로고
    • Expression of growth regulatory genes in primary human testicular neoplasms
    • Engstrom W et al (1987) Expression of growth regulatory genes in primary human testicular neoplasms. Int J Androl 10:79-84
    • (1987) Int J Androl , vol.10 , pp. 79-84
    • Engstrom, W.1
  • 143
    • 0028271924 scopus 로고
    • Insulin-like growth factors, their binding proteins, and transforming growth factor-1 in oxidant-arrested lung alveolar epithelial cells
    • Cazals V et al (1994) Insulin-like growth factors, their binding proteins, and transforming growth factor-1 in oxidant-arrested lung alveolar epithelial cells. J Biol Chem 269:14111-14117
    • (1994) J Biol Chem , vol.269 , pp. 14111-14117
    • Cazals, V.1
  • 144
    • 84995842127 scopus 로고
    • Insulin-like growth factor-binding protein-2: The effect of human chorionic gonadotropin on its gene regulation and protein secretion and its biological effects in rat Leydig cells
    • Wang D et al (1994) Insulin-like growth factor-binding protein-2: the effect of human chorionic gonadotropin on its gene regulation and protein secretion and its biological effects in rat Leydig cells. Mol Endocrinol 8:69-76
    • (1994) Mol Endocrinol , vol.8 , pp. 69-76
    • Wang, D.1
  • 145
    • 53549084852 scopus 로고    scopus 로고
    • IGFBP2 is overexpressed by pediatric malignant astrocytomas and induces the repair enzyme DNA-PK
    • Becher OJ et al (2008) IGFBP2 is overexpressed by pediatric malignant astrocytomas and induces the repair enzyme DNA-PK. J Child Neurol 23:1205-1213
    • (2008) J Child Neurol , vol.23 , pp. 1205-1213
    • Becher, O.J.1
  • 146
    • 0035809056 scopus 로고    scopus 로고
    • Distinct patterns of insulin-like growth factor binding protein (IGFBP)-2 and IGFBP-3 expression in oxidant exposed lung epithelial cells
    • Besnard V et al (2001) Distinct patterns of insulin-like growth factor binding protein (IGFBP)-2 and IGFBP-3 expression in oxidant exposed lung epithelial cells. Biochem Biophys Acta 1538:47-58
    • (2001) Biochem Biophys Acta , vol.1538 , pp. 47-58
    • Besnard, V.1
  • 147
    • 0346095211 scopus 로고    scopus 로고
    • Increased activity of catalase in tumor cells overexpressing IGFBP-2
    • Hoeflich A et al (2003) Increased activity of catalase in tumor cells overexpressing IGFBP-2. Horm Metab Res 35:816-821
    • (2003) Horm Metab Res , vol.35 , pp. 816-821
    • Hoeflich, A.1
  • 148
    • 65949092330 scopus 로고    scopus 로고
    • MicroRNA signature of primary pigmented nodular adrenocortical disease: Clinical correlations and regulation of Wnt signaling
    • Iliopoulos D et al (2009) MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling. Cancer Res 69:3278-3282
    • (2009) Cancer Res , vol.69 , pp. 3278-3282
    • Iliopoulos, D.1
  • 149
    • 59849101194 scopus 로고    scopus 로고
    • New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors
    • Stratakis CA (2009) New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors. Mol Cell Endocrinol 300:152-157
    • (2009) Mol Cell Endocrinol , vol.300 , pp. 152-157
    • Stratakis, C.A.1
  • 150
    • 34147103776 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 triggers the matricrine action of insulinlike growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix
    • Miyamoto S et al (2007) Matrix metalloproteinase-7 triggers the matricrine action of insulinlike growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix. Cancer Sci 98:685-91
    • (2007) Cancer Sci , vol.98 , pp. 685-691
    • Miyamoto, S.1
  • 151
    • 59249104804 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas
    • Rorive S et al (2008) Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas. Glia 56:1679-1690
    • (2008) Glia , vol.56 , pp. 1679-1690
    • Rorive, S.1
  • 152
    • 0032910693 scopus 로고    scopus 로고
    • Role for NF-KB in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells
    • Cazals V et al (1999) Role for NF-KB in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells. Biochim Biophys Acta 1448:349-362
    • (1999) Biochim Biophys Acta , vol.1448 , pp. 349-362
    • Cazals, V.1
  • 153
    • 35148818315 scopus 로고    scopus 로고
    • IGF2 and IGFBP-2 differentially regulate PTEN in human breast cancer cells
    • Perks CM et al (2007) IGF2 and IGFBP-2 differentially regulate PTEN in human breast cancer cells. Oncogene 26:5966-5972
    • (2007) Oncogene , vol.26 , pp. 5966-5972
    • Perks, C.M.1
  • 154
    • 27744440723 scopus 로고    scopus 로고
    • PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF2 expression in gastric cancer cells
    • Hwang PH et al (2005) PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF2 expression in gastric cancer cells. Exp Mol Med 37:391-398
    • (2005) Exp Mol Med , vol.37 , pp. 391-398
    • Hwang, P.H.1
  • 155
    • 0347379897 scopus 로고    scopus 로고
    • Insulin-like growth factor-II regulates PTEN expression in the mammary gland
    • Moorehead RA et al (2003) Insulin-like growth factor-II regulates PTEN expression in the mammary gland. J Biol Chem 278:50422-50427
    • (2003) J Biol Chem , vol.278 , pp. 50422-50427
    • Moorehead, R.A.1
  • 156
    • 34547474942 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 2 promotes glioma development and progression
    • Dunlap SM et al (2007) Insulin-like growth factor binding protein 2 promotes glioma development and progression. PNAS 104:11736-11741
    • (2007) PNAS , vol.104 , pp. 11736-11741
    • Dunlap, S.M.1
  • 157
    • 0038540597 scopus 로고    scopus 로고
    • PTEN modulates insulin-like growth factor II (IGF2)-mediated signaling; the protein phosphatase activity of PTEN downregulates IGF2 expression in hepatoma cells
    • Kang-Park S, Lee YI (2003) PTEN modulates insulin-like growth factor II (IGF2)-mediated signaling; the protein phosphatase activity of PTEN downregulates IGF2 expression in hepatoma cells. FEBS Lett 545:203-208
    • (2003) FEBS Lett , vol.545 , pp. 203-208
    • Kang-Park, S.1    Lee, Y.I.2
  • 158
    • 34249804521 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway
    • Martin JL, Baxter RC (2007) Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway. Endocrinology 148:2532-41
    • (2007) Endocrinology , vol.148 , pp. 2532-2541
    • Martin, J.L.1    Baxter, R.C.2
  • 159
    • 33644689975 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-2 stimulates proliferation and activates multiple cascades of the mitogen-activated protein kinase pathways in NIH-OVCAR3 human epithelial ovarian cancer cells
    • Chakrabarty S, Kondratick L (2006) Insulin-like growth factor binding protein-2 stimulates proliferation and activates multiple cascades of the mitogen-activated protein kinase pathways in NIH-OVCAR3 human epithelial ovarian cancer cells. Cancer Biol Ther 5:189-197
    • (2006) Cancer Biol Ther , vol.5 , pp. 189-197
    • Chakrabarty, S.1    Kondratick, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.