IGFBP2 is overexpressed by pediatric malignant astrocytomas and induces the repair enzyme DNA-PK

Journal of Child Neurology

Volumn 23, Issue 10, 2008, Pages 1205-1213

  Becher, Oren J ^b   Peterson, Katia M ^b   Khatua, Soumen ^b   Santi, Maria R ^b   MacDonald, Tobey J ^a,b  

^a CHILDREN S RESEARCH INSTITUTE   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Astrocytoma; Childhood; DNA PK; IGFBP2

Indexed keywords

DNA DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN TYROSINE KINASE; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ASTROCYTOMA; CELL GROWTH; CELL MIGRATION; CHILDHOOD CANCER; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DNA REPAIR; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALIGNANT TRANSFORMATION; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; UPREGULATION;

ASTROCYTOMA; BRAIN NEOPLASMS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHILD; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NUCLEAR PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 53549084852     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073808321766     Document Type: Conference Paper

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