Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells

Endocrinology

Volumn 144, Issue 6, 2003, Pages 2695-2703

  Zaina, Silvio ^a,c   Pettersson, Linda ^a   Thomsen, Anne Bloch ^a   Chai, Chun Ming ^a   Qi, Zhongquan ^a   Thyberg, Johan ^b   Nilsson, Jan ^a  

^a LUND UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN B;

ANIMAL TISSUE; AORTA INTIMA; AUTOPSY; BRADYCARDIA; CARDIOMEGALY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HETEROZYGOTE; HISTOPATHOLOGY; HYPOTENSION; LIFESPAN; MALE; MOUSE; MUTANT; NONHUMAN; ORGAN SIZE; PHENOTYPE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; AORTA; BLOOD PRESSURE; BODY CONSTITUTION; BRADYCARDIA; ELECTROCARDIOGRAPHY; FEMALE; GENE EXPRESSION; HEART DEFECTS, CONGENITAL; HETEROZYGOTE; HYPOTENSION; INSULIN-LIKE GROWTH FACTOR II; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; SEX DISTRIBUTION; SURVIVAL RATE; TRANSGENES;

EID: 0037846124     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220944     Document Type: Conference Paper

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