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Volumn 181, Issue 3, 2012, Pages 928-936

Hypercholesterolemia promotes an osteoporotic phenotype

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CHOLIC ACID;

EID: 84865210268     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.05.034     Document Type: Article
Times cited : (78)

References (63)
  • 1
    • 22044443714 scopus 로고    scopus 로고
    • Clinical practice: Screening for osteoporosis
    • L.G. Raisz Clinical practice Screening for osteoporosis N Engl J Med 353 2005 164 171
    • (2005) N Engl J Med , vol.353 , pp. 164-171
    • Raisz, L.G.1
  • 2
    • 79953751008 scopus 로고    scopus 로고
    • Osteoporosis: Now and the future
    • T.D. Rachner, S. Khosla, L.C. Hofbauer Osteoporosis: now and the future Lancet 377 2011 1276 1287
    • (2011) Lancet , vol.377 , pp. 1276-1287
    • Rachner, T.D.1    Khosla, S.2    Hofbauer, L.C.3
  • 5
    • 0036264588 scopus 로고    scopus 로고
    • Cardiovascular disease and osteoporosis: Is there a link between lipids and bone?
    • J.R. Burnett, S.D. Vasikaran Cardiovascular disease and osteoporosis: is there a link between lipids and bone? Ann Clin Biochem 39 2002 203 210
    • (2002) Ann Clin Biochem , vol.39 , pp. 203-210
    • Burnett, J.R.1    Vasikaran, S.D.2
  • 6
    • 18344369180 scopus 로고    scopus 로고
    • Coexistence of osteoporosis and cardiovascular disease risk factors in apparently healthy, untreated postmenopausal women
    • P.G. Masse, C.C. Tranchant, J. Dosy, S.M. Donovan Coexistence of osteoporosis and cardiovascular disease risk factors in apparently healthy, untreated postmenopausal women Int J Vitam Nutr Res 75 2005 97 106
    • (2005) Int J Vitam Nutr Res , vol.75 , pp. 97-106
    • Masse, P.G.1    Tranchant, C.C.2    Dosy, J.3    Donovan, S.M.4
  • 7
    • 2442540370 scopus 로고    scopus 로고
    • Osteoporosis and cardiovascular disease: Brittle bones and boned arteries, is there a link?
    • S.I. McFarlane, R. Muniyappa, J.J. Shin, G. Bahtiyar, J.R. Sowers Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link? Endocrine 23 2004 1 10
    • (2004) Endocrine , vol.23 , pp. 1-10
    • McFarlane, S.I.1    Muniyappa, R.2    Shin, J.J.3    Bahtiyar, G.4    Sowers, J.R.5
  • 8
    • 0036180503 scopus 로고    scopus 로고
    • The influence of hormonal status and features of the metabolic syndrome on bone density: A population-based study of Swedish women aged 50 to 59 years. The women's health in the Lund area study
    • J. Lidfeldt, L. Holmdahl, G. Samsioe, C. Nerbrand, P. Nyberg, B. Schersten, C.D. Agardh The influence of hormonal status and features of the metabolic syndrome on bone density: a population-based study of Swedish women aged 50 to 59 years. The women's health in the Lund area study Metabolism 51 2002 267 270
    • (2002) Metabolism , vol.51 , pp. 267-270
    • Lidfeldt, J.1    Holmdahl, L.2    Samsioe, G.3    Nerbrand, C.4    Nyberg, P.5    Schersten, B.6    Agardh, C.D.7
  • 9
    • 34548547438 scopus 로고    scopus 로고
    • Associations between the metabolic syndrome and bone health in older men and women: The Rancho Bernardo Study
    • D. von Muhlen, S. Safii, S.K. Jassal, J. Svartberg, E. Barrett-Connor Associations between the metabolic syndrome and bone health in older men and women: the Rancho Bernardo Study Osteoporos Int 18 2007 1337 1344
    • (2007) Osteoporos Int , vol.18 , pp. 1337-1344
    • Von Muhlen, D.1    Safii, S.2    Jassal, S.K.3    Svartberg, J.4    Barrett-Connor, E.5
  • 10
    • 58649094407 scopus 로고    scopus 로고
    • Decreased bone mineral density in men with metabolic syndrome alone and with type 2 diabetes
    • S. Yaturu, S. Humphrey, C. Landry, S.K. Jain Decreased bone mineral density in men with metabolic syndrome alone and with type 2 diabetes Med Sci Monit 15 2009 CR5 CR9
    • (2009) Med Sci Monit , vol.15
    • Yaturu, S.1    Humphrey, S.2    Landry, C.3    Jain, S.K.4
  • 11
    • 0036791574 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • F.R. Maxfield, D. Wustner Intracellular cholesterol transport J Clin Invest 110 2002 891 898
    • (2002) J Clin Invest , vol.110 , pp. 891-898
    • Maxfield, F.R.1    Wustner, D.2
  • 13
    • 7044223211 scopus 로고    scopus 로고
    • Maintaining cholesterol homeostasis: Sterol regulatory element-binding proteins
    • L.W. Weber, M. Boll, A. Stampfl Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins World J Gastroenterol 10 2004 3081 3087
    • (2004) World J Gastroenterol , vol.10 , pp. 3081-3087
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 14
    • 0027614288 scopus 로고
    • Interrelations between body weight, cigarette smoking and spine mineral density in osteoporotic Czech women
    • P.D. Broulik, J. Kapitola Interrelations between body weight, cigarette smoking and spine mineral density in osteoporotic Czech women Endocr Regul 27 1993 57 60
    • (1993) Endocr Regul , vol.27 , pp. 57-60
    • Broulik, P.D.1    Kapitola, J.2
  • 15
    • 13644268580 scopus 로고    scopus 로고
    • Atherogenic lipid profile and elevated lipoprotein(a) are associated with lower bone mineral density in early postmenopausal overweight women
    • P. Orozco Atherogenic lipid profile and elevated lipoprotein(a) are associated with lower bone mineral density in early postmenopausal overweight women Eur J Epidemiol 19 2004 1105 1112
    • (2004) Eur J Epidemiol , vol.19 , pp. 1105-1112
    • Orozco, P.1
  • 16
    • 0037635964 scopus 로고    scopus 로고
    • Possible role of oxidized lipids in osteoporosis: Could hyperlipidemia be a risk factor?
    • F. Parhami Possible role of oxidized lipids in osteoporosis: could hyperlipidemia be a risk factor? Prostaglandins Leukot Essent Fatty Acids 68 2003 373 378
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.68 , pp. 373-378
    • Parhami, F.1
  • 19
    • 67349281950 scopus 로고    scopus 로고
    • Analysis of skeletal status by quantitative ultrasonometry in a cohort of postmenopausal women with high blood cholesterol without documented osteoporosis
    • V. Nuzzo, A.M. de Milita, T. Ferraro, A. Monaco, E. Florio, P. Miano, E. Montemarano, A. Zuccoli, F. de Terlizzi Analysis of skeletal status by quantitative ultrasonometry in a cohort of postmenopausal women with high blood cholesterol without documented osteoporosis Ultrasound Med Biol 35 2009 717 722
    • (2009) Ultrasound Med Biol , vol.35 , pp. 717-722
    • Nuzzo, V.1    De Milita, A.M.2    Ferraro, T.3    Monaco, A.4    Florio, E.5    Miano, P.6    Montemarano, E.7    Zuccoli, A.8    De Terlizzi, F.9
  • 21
    • 0242628033 scopus 로고    scopus 로고
    • Plasma low-density lipoprotein cholesterol and bone mass densitometry in postmenopausal women
    • A. Poli, F. Bruschi, B. Cesana, M. Rossi, R. Paoletti, P.G. Crosignani Plasma low-density lipoprotein cholesterol and bone mass densitometry in postmenopausal women Obstet Gynecol 102 2003 922 926
    • (2003) Obstet Gynecol , vol.102 , pp. 922-926
    • Poli, A.1    Bruschi, F.2    Cesana, B.3    Rossi, M.4    Paoletti, R.5    Crosignani, P.G.6
  • 22
    • 0029957678 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors
    • J.P. Desager, Y. Horsmans Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors Clin Pharmacokinet 31 1996 348 371
    • (1996) Clin Pharmacokinet , vol.31 , pp. 348-371
    • Desager, J.P.1    Horsmans, Y.2
  • 23
    • 0027819738 scopus 로고
    • Tissue selectivity of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase inhibitors
    • C.R. Sirtori Tissue selectivity of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase inhibitors Pharmacol Ther 60 1993 431 459
    • (1993) Pharmacol Ther , vol.60 , pp. 431-459
    • Sirtori, C.R.1
  • 24
    • 42949170875 scopus 로고    scopus 로고
    • Do the cholesterol-lowering properties of statins affect cancer risk?
    • K.R. Solomon, M.R. Freeman Do the cholesterol-lowering properties of statins affect cancer risk? Trends Endocrinol Metab 19 2008 113 121
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 113-121
    • Solomon, K.R.1    Freeman, M.R.2
  • 26
    • 0036771113 scopus 로고    scopus 로고
    • Pleiotropic effects of HMG-CoA reductase inhibitors
    • T.M. Bocan Pleiotropic effects of HMG-CoA reductase inhibitors Curr Opin Investig Drugs 3 2002 1312 1317
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 1312-1317
    • Bocan, T.M.1
  • 29
  • 31
    • 0035212177 scopus 로고    scopus 로고
    • Statins and their potential for osteoporosis
    • G.R. Mundy Statins and their potential for osteoporosis Bone 29 2001 495 497
    • (2001) Bone , vol.29 , pp. 495-497
    • Mundy, G.R.1
  • 32
    • 0033957938 scopus 로고    scopus 로고
    • Statins: Lower lipids and better bones?
    • M.J. Rogers Statins: lower lipids and better bones? Nat Med 6 2000 21 23
    • (2000) Nat Med , vol.6 , pp. 21-23
    • Rogers, M.J.1
  • 34
    • 0346690415 scopus 로고    scopus 로고
    • The pleiotropic effects of HMG-CoA reductase inhibitors: Their role in osteoporosis and dementia
    • A. Waldman, L. Kritharides The pleiotropic effects of HMG-CoA reductase inhibitors: their role in osteoporosis and dementia Drugs 63 2003 139 152
    • (2003) Drugs , vol.63 , pp. 139-152
    • Waldman, A.1    Kritharides, L.2
  • 35
    • 0034725357 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients [see comments]
    • P.S. Wang, D.H. Solomon, H. Mogun, J. Avorn HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients [see comments] JAMA 283 2000 3211 3216
    • (2000) JAMA , vol.283 , pp. 3211-3216
    • Wang, P.S.1    Solomon, D.H.2    Mogun, H.3    Avorn, J.4
  • 36
    • 0036118915 scopus 로고    scopus 로고
    • Pleiotropic effects of HMG-CoA reductase inhibitors
    • N. Werner, G. Nickenig, U. Laufs Pleiotropic effects of HMG-CoA reductase inhibitors Basic Res Cardiol 97 2002 105 116
    • (2002) Basic Res Cardiol , vol.97 , pp. 105-116
    • Werner, N.1    Nickenig, G.2    Laufs, U.3
  • 37
    • 0035110689 scopus 로고    scopus 로고
    • Statins: New drugs for treating osteoporosis?
    • J.F. Whitfield Statins: new drugs for treating osteoporosis? Expert Opin Investig Drugs 10 2001 409 415
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 409-415
    • Whitfield, J.F.1
  • 38
  • 39
    • 0036224272 scopus 로고    scopus 로고
    • Statins and osteoporosis: Can these lipid-lowering drugs also bolster bones?
    • A.C. Cruz, B.L. Gruber Statins and osteoporosis: can these lipid-lowering drugs also bolster bones? Cleve Clin J Med 69 2002 277 278 280282, 287288
    • (2002) Cleve Clin J Med , vol.69 , pp. 277-278
    • Cruz, A.C.1    Gruber, B.L.2
  • 40
    • 0026567257 scopus 로고
    • Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor: CI-981: comparison with selected HMG-CoA reductase inhibitors
    • T.M. Bocan, E. Ferguson, W. McNally, P.D. Uhlendorf, S. Bak Mueller, P. Dehart, D.R. Sliskovic, B.D. Roth, B.R. Krause, R.S. Newton Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor: CI-981: comparison with selected HMG-CoA reductase inhibitors Biochim Biophys Acta 1123 1992 133 144
    • (1992) Biochim Biophys Acta , vol.1123 , pp. 133-144
    • Bocan, T.M.1    Ferguson, E.2    McNally, W.3    Uhlendorf, P.D.4    Bak Mueller, S.5    Dehart, P.6    Sliskovic, D.R.7    Roth, B.D.8    Krause, B.R.9    Newton, R.S.10
  • 41
    • 0028929401 scopus 로고
    • Pharmacology of competitive inhibitors of HMG-CoA reductase
    • A. Corsini, F.M. Maggi, A.L. Catapano Pharmacology of competitive inhibitors of HMG-CoA reductase Pharmacol Res 31 1995 9 27
    • (1995) Pharmacol Res , vol.31 , pp. 9-27
    • Corsini, A.1    Maggi, F.M.2    Catapano, A.L.3
  • 45
    • 0025286202 scopus 로고
    • Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
    • T. Koga, Y. Shimada, M. Kuroda, Y. Tsujita, K. Hasegawa, M. Yamazaki Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Biochim Biophys Acta 1045 1990 115 120
    • (1990) Biochim Biophys Acta , vol.1045 , pp. 115-120
    • Koga, T.1    Shimada, Y.2    Kuroda, M.3    Tsujita, Y.4    Hasegawa, K.5    Yamazaki, M.6
  • 47
    • 0025348680 scopus 로고
    • Selective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitors
    • R.A. Parker, R.W. Clark, S.Y. Sit, T.L. Lanier, R.A. Grosso, J.J. Wright Selective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitors J Lipid Res 31 1990 1271 1282
    • (1990) J Lipid Res , vol.31 , pp. 1271-1282
    • Parker, R.A.1    Clark, R.W.2    Sit, S.Y.3    Lanier, T.L.4    Grosso, R.A.5    Wright, J.J.6
  • 48
    • 0025076205 scopus 로고
    • Disposition of fluvastatin, an inhibitor of HMG-COA reductase, in mouse, rat, dog, and monkey
    • F.L. Tse, H.T. Smith, F.H. Ballard, J. Nicoletti Disposition of fluvastatin, an inhibitor of HMG-COA reductase, in mouse, rat, dog, and monkey Biopharm Drug Dispos 11 1990 519 531
    • (1990) Biopharm Drug Dispos , vol.11 , pp. 519-531
    • Tse, F.L.1    Smith, H.T.2    Ballard, F.H.3    Nicoletti, J.4
  • 49
  • 50
    • 0036708020 scopus 로고    scopus 로고
    • A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin
    • C.M. White A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin J Clin Pharmacol 42 2002 963 970
    • (2002) J Clin Pharmacol , vol.42 , pp. 963-970
    • White, C.M.1
  • 52
    • 82955194969 scopus 로고    scopus 로고
    • High cholesterol diet increases osteoporosis risk via inhibiting bone formation in rats
    • You L, Sheng ZY, Tang CL, Chen L, Pan L, Chen JY: High cholesterol diet increases osteoporosis risk via inhibiting bone formation in rats. Acta Pharmacol Sin 32:14981504
    • Acta Pharmacol Sin , vol.32 , pp. 1498-1504
    • You, L.1    Sheng, Z.Y.2    Tang, C.L.3    Chen, L.4    Pan, L.5    Chen, J.Y.6
  • 54
    • 84865255159 scopus 로고    scopus 로고
    • Densitometric survey of 11 inbred strains of mice. MPD:224, Jaxpheno1
    • The Jackson Laboratory
    • The Jackson Laboratory Densitometric survey of 11 inbred strains of mice. MPD:224, Jaxpheno1 Mouse Phenome Database 2006
    • (2006) Mouse Phenome Database
  • 55
    • 0029880186 scopus 로고    scopus 로고
    • Genetic variability in adult bone density among inbred strains of mice
    • W.G. Beamer, L.R. Donahue, C.J. Rosen, D.J. Baylink Genetic variability in adult bone density among inbred strains of mice Bone 18 1996 397 403
    • (1996) Bone , vol.18 , pp. 397-403
    • Beamer, W.G.1    Donahue, L.R.2    Rosen, C.J.3    Baylink, D.J.4
  • 56
    • 12344331677 scopus 로고    scopus 로고
    • Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density
    • J.E. Wergedal, M.H. Sheng, C.L. Ackert-Bicknell, W.G. Beamer, D.J. Baylink Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density Bone 36 2005 111 122
    • (2005) Bone , vol.36 , pp. 111-122
    • Wergedal, J.E.1    Sheng, M.H.2    Ackert-Bicknell, C.L.3    Beamer, W.G.4    Baylink, D.J.5
  • 58
    • 84855854953 scopus 로고    scopus 로고
    • Osteoporosis and inflammation
    • G.R. Mundy Osteoporosis and inflammation Nutr Rev 65 2007 S147 S151
    • (2007) Nutr Rev , vol.65
    • Mundy, G.R.1
  • 61
    • 1542316221 scopus 로고    scopus 로고
    • Long-term effects of serum cholesterol on bone mineral density in women and men: The Framingham Osteoporosis Study
    • E.J. Samelson, L.A. Cupples, M.T. Hannan, P.W. Wilson, S.A. Williams, V. Vaccarino, Y. Zhang, D.P. Kiel Long-term effects of serum cholesterol on bone mineral density in women and men: the Framingham Osteoporosis Study Bone 34 2004 557 561
    • (2004) Bone , vol.34 , pp. 557-561
    • Samelson, E.J.1    Cupples, L.A.2    Hannan, M.T.3    Wilson, P.W.4    Williams, S.A.5    Vaccarino, V.6    Zhang, Y.7    Kiel, D.P.8
  • 63
    • 0032813836 scopus 로고    scopus 로고
    • Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate
    • A.H. Lichtman, S.K. Clinton, K. Iiyama, P.W. Connelly, P. Libby, M.I. Cybulsky Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate Arterioscler Thromb Vasc Biol 19 1999 1938 1944
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1938-1944
    • Lichtman, A.H.1    Clinton, S.K.2    Iiyama, K.3    Connelly, P.W.4    Libby, P.5    Cybulsky, M.I.6


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