High cholesterol diet increases osteoporosis risk via inhibiting bone formation in rats

Acta Pharmacologica Sinica

Volumn 32, Issue 12, 2011, Pages 1498-1504

  You, Li ^a   Sheng, Zheng Yan ^a   Tang, Chuan Ling ^b   Chen, Lin ^a   Pan, Ling ^a   Chen, Jin Yu ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

bone morphogenic protein; high cholesterol diet; hypercholesterolaemia; osteoblasts; osteoporosis; oxidative stress

Indexed keywords

ADVANCED GLYCATION END PRODUCT; APOLIPOPROTEIN E; BETA1 INTERFERON; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 6; CALCITONIN RECEPTOR; CARBOXY TERMINAL TELOPEPTIDE; CAVEOLIN; CHOLESTEROL; ESTRADIOL; FIBROBLAST GROWTH FACTOR 5; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR 2; INTERLEUKIN 6; LEPTIN RECEPTOR; MALONALDEHYDE; NEUTROPHIL COLLAGENASE; OSTEOCALCIN; SOMATOMEDIN BINDING PROTEIN 5; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRIACYLGLYCEROL; WNT5A PROTEIN;

AGERATINA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CLINICAL ASSESSMENT; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION PROFILING; IN VITRO STUDY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; OVARIECTOMY; OXIDATIVE STRESS; QUANTITATIVE ASSAY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

3T3 CELLS; ABSORPTIOMETRY, PHOTON; ANIMALS; BASE SEQUENCE; BONE DENSITY; BONE DEVELOPMENT; CHOLESTEROL, DIETARY; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION PROFILING; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 82955194969     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.135     Document Type: Article

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