Imaging mass spectrometry to visualize biomolecule distributions in mouse brain tissue following hemispheric cortical spreading depression

Journal of Proteomics

Volumn 75, Issue 16, 2012, Pages 5027-5035

  Jones, Emrys A ^a   Shyti, Reinald ^a   van Zeijl, René J M ^a   van Heiningen, Sandra H ^a   Ferrari, Michel D ^a   Deelder, André M ^a   Tolner, Else A ^a   van den Maagdenberg, Arn M J M ^a   McDonnell, Liam A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cortical spreading depression; CSD; Imaging mass spectrometry; MALDI; Molecular histology

Indexed keywords

NEUROPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; BRAIN TISSUE; COMPUTER PROGRAM; CONTROLLED STUDY; DEPOLARIZATION; GLIA; HEMISPHERE; HISTOCHEMISTRY; HISTOPATHOLOGY; IMAGING MASS SPECTROMETRY; IMAGING SYSTEM; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLITE; MOLECULAR BIOLOGY; MOUSE; NON NEGATIVE MATRIX FACTORIZATION; NONHUMAN; PRIORITY JOURNAL; PROOF OF PRINCIPLE IMAGING; PROTEIN ANALYSIS; PROTEIN DATABASE; SPREADING CORTICAL DEPRESSION;

ANIMALS; BIOLOGICAL FACTORS; BRAIN; BRAIN CHEMISTRY; COMPUTER SIMULATION; CORTICAL SPREADING DEPRESSION; DIAGNOSTIC IMAGING; HISTOCYTOCHEMISTRY; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; PEPTIDES; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TISSUE DISTRIBUTION;

EID: 84865199104     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2012.06.025     Document Type: Article

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