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Volumn 6, Issue 10, 2007, Pages 3952-3961

Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins

Author keywords

6 OHDA; Mass spectrometry; Parkinson's disease; Protein interactions; Proteomics; Striatum

Indexed keywords

14 3 3 DELTA PYRUVATE KINASE; 14 3 3 ZETA PYRUVATE KINASE; ALPHA ENOLASE; FK 506 BINDING PROTEIN; HEAT SHOCK PROTEIN 70; IMMUNOPHILIN; MESSENGER RNA; OXIDOPAMINE; PYRUVATE KINASE; UNCLASSIFIED DRUG;

EID: 35648966146     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr070189e     Document Type: Article
Times cited : (28)

References (61)
  • 1
    • 0015626895 scopus 로고
    • Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA)
    • Hornykiewicz, O. Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA). Br. Med. Bull. 1973, 29 (2), 172-178.
    • (1973) Br. Med. Bull , vol.29 , Issue.2 , pp. 172-178
    • Hornykiewicz, O.1
  • 2
    • 2442570592 scopus 로고    scopus 로고
    • Disease modification in Parkinson's disease
    • Schapira, A. H. Disease modification in Parkinson's disease. Lancet Neurol. 2004, 3 (6), 362-368.
    • (2004) Lancet Neurol , vol.3 , Issue.6 , pp. 362-368
    • Schapira, A.H.1
  • 3
    • 2542596183 scopus 로고    scopus 로고
    • Parkinson's disease
    • Samii, A.; Nutt, J. G.; Ransom, P. B. R., Parkinson's disease. Lancet 2004, 363 (9423), 1783-1793.
    • (2004) Lancet , vol.363 , Issue.9423 , pp. 1783-1793
    • Samii, A.1    Nutt, J.G.2    Ransom, P.B.R.3
  • 4
    • 0030744876 scopus 로고    scopus 로고
    • Polymeropoulos, M. H.; Lavedan, C.; Leroy, E.; Ide, S. E.; Dehejia, A.; Dutra, A.; Pike, B.; Root, H.; Rubenstein, J.; Boyer, R.; Stenroos, E. S.; Chandrasekharappa, S.; Athanassiadou, A.; Papapetropoulos, T.; Johnson, W. G.; Lazzarini, A. M.; Duvoisin, R. C.; Di, Iorio, G.; Golbe, L. I.; Nussbaum, R. L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276 (5321), 2045-2047.
    • Polymeropoulos, M. H.; Lavedan, C.; Leroy, E.; Ide, S. E.; Dehejia, A.; Dutra, A.; Pike, B.; Root, H.; Rubenstein, J.; Boyer, R.; Stenroos, E. S.; Chandrasekharappa, S.; Athanassiadou, A.; Papapetropoulos, T.; Johnson, W. G.; Lazzarini, A. M.; Duvoisin, R. C.; Di, Iorio, G.; Golbe, L. I.; Nussbaum, R. L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276 (5321), 2045-2047.
  • 6
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • Kish, S. J.; Shannak, K.; Hornykiewicz, O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N. Engl. J. Med. 1988, 318 (14), 876-880.
    • (1988) N. Engl. J. Med , vol.318 , Issue.14 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 7
    • 0036462452 scopus 로고    scopus 로고
    • Neuroimmunophilin ligands in the treatment of Parkinson's disease
    • Gold, B. G.; Nutt, J. G. Neuroimmunophilin ligands in the treatment of Parkinson's disease. Curr. Opin. Pharmacol. 2002, 2 (1), 82-86.
    • (2002) Curr. Opin. Pharmacol , vol.2 , Issue.1 , pp. 82-86
    • Gold, B.G.1    Nutt, J.G.2
  • 8
    • 0032142911 scopus 로고    scopus 로고
    • Immunophilins in the nervous system
    • Snyder, S. H.; Lai, M. M.; Burnett, P. E. Immunophilins in the nervous system. Neuron 1998, 21 (2), 283-294.
    • (1998) Neuron , vol.21 , Issue.2 , pp. 283-294
    • Snyder, S.H.1    Lai, M.M.2    Burnett, P.E.3
  • 9
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu, J.; Farmer, J. Jesse, D.; Lane, W. S.; Friedman, J.; Weissman, I.; Schreiber, S. L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66 (4), 807-815.
    • (1991) Cell , vol.66 , Issue.4 , pp. 807-815
    • Liu, J.1    Farmer, J.2    Jesse, D.3    Lane, W.S.4    Friedman, J.5    Weissman, I.6    Schreiber, S.L.7
  • 10
    • 0031660913 scopus 로고    scopus 로고
    • A novel immunophilin ligand: Distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease
    • Costantini, L. C.; Chaturvedi, P.; Armistead, D. M.; McCaffrey, P. G.; Deacon, T. W.; Isacson, O. A novel immunophilin ligand: distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease. Neurobiol. Dis. 1998, 5 (2), 97-106.
    • (1998) Neurobiol. Dis , vol.5 , Issue.2 , pp. 97-106
    • Costantini, L.C.1    Chaturvedi, P.2    Armistead, D.M.3    McCaffrey, P.G.4    Deacon, T.W.5    Isacson, O.6
  • 11
    • 0028783373 scopus 로고
    • The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve
    • Gold, B.; Katoh, K.; Storm-Dickerson, T. The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve. J. Neurosci. 1995, 15 (11), 7509-7516.
    • (1995) J. Neurosci , vol.15 , Issue.11 , pp. 7509-7516
    • Gold, B.1    Katoh, K.2    Storm-Dickerson, T.3
  • 12
    • 0032411557 scopus 로고    scopus 로고
    • Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats
    • Madsen, J. R.; MacDonald, P.; Irwin, N.; Goldberg, D. E.; Yao, G.-L.; Meiri, K. F.; Rimm, I. J.; Stieg, P. E.; Benowitz, L. I., Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp. Neurol. 1998, 154 (2), 673-683.
    • (1998) Exp. Neurol , vol.154 , Issue.2 , pp. 673-683
    • Madsen, J.R.1    MacDonald, P.2    Irwin, N.3    Goldberg, D.E.4    Yao, G.-L.5    Meiri, K.F.6    Rimm, I.J.7    Stieg, P.E.8    Benowitz, L.I.9
  • 13
    • 0032816454 scopus 로고    scopus 로고
    • The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: Neuroprotection and local regeneration
    • Bavetta, S.; Hamlyn, P. J.; Burnstock, G.; Lieberman, A. R.; Anderson, P. N. The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. Exp. Neurol. 1999, 158 (2), 382-393.
    • (1999) Exp. Neurol , vol.158 , Issue.2 , pp. 382-393
    • Bavetta, S.1    Hamlyn, P.J.2    Burnstock, G.3    Lieberman, A.R.4    Anderson, P.N.5
  • 14
    • 0031309575 scopus 로고    scopus 로고
    • Gold, B. G. FK506 and the role of immunophilins in nerve regeneration. Mol. Neurobiol. 1997, 15 (3), 285-306.
    • Gold, B. G. FK506 and the role of immunophilins in nerve regeneration. Mol. Neurobiol. 1997, 15 (3), 285-306.
  • 16
    • 0032602932 scopus 로고    scopus 로고
    • Calcineurin. Structure, function, and inhibition
    • Hemenway, C. S.; Heitman, J. Calcineurin. Structure, function, and inhibition. Cell Biochem. Biophys. 1999, 30 (1), 115-151.
    • (1999) Cell Biochem. Biophys , vol.30 , Issue.1 , pp. 115-151
    • Hemenway, C.S.1    Heitman, J.2
  • 17
    • 0031027178 scopus 로고    scopus 로고
    • Early developmental destruction of terminals in the striatal target induces apoptosis in dopamine neurons of the substantia nigra
    • Marti, M. J.; James, C. J.; Oo, T. F.; Kelly, W. J.; Burke, R. E. Early developmental destruction of terminals in the striatal target induces apoptosis in dopamine neurons of the substantia nigra. J. Neurosci. 1997, 17 (6), 2030-2039.
    • (1997) J. Neurosci , vol.17 , Issue.6 , pp. 2030-2039
    • Marti, M.J.1    James, C.J.2    Oo, T.F.3    Kelly, W.J.4    Burke, R.E.5
  • 18
    • 0033168508 scopus 로고    scopus 로고
    • Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK
    • Choi, W. S.; Yoon, S. Y.; Oh, T. H.; Choi, E. J.; O'Malley, K. L.; Oh, Y. J. Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: role of caspases, ROS, and JNK. J. Neurosci. Res. 1999, 57 (1), 86-94.
    • (1999) J. Neurosci. Res , vol.57 , Issue.1 , pp. 86-94
    • Choi, W.S.1    Yoon, S.Y.2    Oh, T.H.3    Choi, E.J.4    O'Malley, K.L.5    Oh, Y.J.6
  • 19
    • 0032880190 scopus 로고    scopus 로고
    • Neurophilins and the nervous system
    • Mikol, D. D.; Feldman, E. L. Neurophilins and the nervous system. Muscle Nerve 1999, 22 (10), 1337-1340.
    • (1999) Muscle Nerve , vol.22 , Issue.10 , pp. 1337-1340
    • Mikol, D.D.1    Feldman, E.L.2
  • 20
    • 4043100606 scopus 로고    scopus 로고
    • Integration of surface plasmon resonance with mass spectrometry: Automated ligand fishing and sample preparation for MALDI MS using a Biacore 3000 biosensor
    • Zhukov, A.; Schurenberg, M.; Jansson, O.; Areskoug, D.; Buijs, J. Integration of surface plasmon resonance with mass spectrometry: automated ligand fishing and sample preparation for MALDI MS using a Biacore 3000 biosensor. J. Biomol. Tech. 2004, 15 (2), 112-119.
    • (2004) J. Biomol. Tech , vol.15 , Issue.2 , pp. 112-119
    • Zhukov, A.1    Schurenberg, M.2    Jansson, O.3    Areskoug, D.4    Buijs, J.5
  • 22
    • 0015184103 scopus 로고
    • Postsynaptic supersensitivity after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system
    • Ungerstedt, U. Postsynaptic supersensitivity after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system. Acta Physiol. Scand. Suppl. 1971, 367, 69-93.
    • (1971) Acta Physiol. Scand. Suppl , vol.367 , pp. 69-93
    • Ungerstedt, U.1
  • 23
    • 0034674936 scopus 로고    scopus 로고
    • L-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset
    • Svenningsson, P.; Gunne, L.; Andren, P. E., L-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset. Neuroscience 2000, 99 (3), 457-468.
    • (2000) Neuroscience , vol.99 , Issue.3 , pp. 457-468
    • Svenningsson, P.1    Gunne, L.2    Andren, P.E.3
  • 24
    • 0021988172 scopus 로고
    • Simplified method for silverstaining of proteins in Polyacrylamide gels and the mechanism of silver staining
    • Heukeshoven, J.; Dernik, R. Simplified method for silverstaining of proteins in Polyacrylamide gels and the mechanism of silver staining. Electrophoresis 1985, 6 (3), 103-112.
    • (1985) Electrophoresis , vol.6 , Issue.3 , pp. 103-112
    • Heukeshoven, J.1    Dernik, R.2
  • 25
    • 0023931883 scopus 로고
    • Improved staining of proteins in Polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250
    • Neuhoff, V.; Arnold, N.; Taub, D.; Erhardt, W. Improved staining of proteins in Polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 1988, 9 (6), 255-262.
    • (1988) Electrophoresis , vol.9 , Issue.6 , pp. 255-262
    • Neuhoff, V.1    Arnold, N.2    Taub, D.3    Erhardt, W.4
  • 26
    • 0024289037 scopus 로고
    • Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons
    • Hillenkamp, M. K. a. F., Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. Anal. Chem. 1988, 60 (20), 2299-2301.
    • (1988) Anal. Chem , vol.60 , Issue.20 , pp. 2299-2301
    • Hillenkamp, M.K.A.F.1
  • 27
    • 0030836031 scopus 로고    scopus 로고
    • Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas
    • Svenningsson, P.; Le Moine, C.; Kull, B.; Sunahara, R.; Bloch, B.; Fredholm, B. B. Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience 1997, 80 (4), 1171-1185.
    • (1997) Neuroscience , vol.80 , Issue.4 , pp. 1171-1185
    • Svenningsson, P.1    Le Moine, C.2    Kull, B.3    Sunahara, R.4    Bloch, B.5    Fredholm, B.B.6
  • 28
    • 0009482260 scopus 로고    scopus 로고
    • Towbin, H.; Staehlin, T.; J. G. Electrophoretic transfer of proteins from Polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 1999, 76 4350-4354.
    • Towbin, H.; Staehlin, T.; J. G. Electrophoretic transfer of proteins from Polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 1999, 76 4350-4354.
  • 29
    • 17444422182 scopus 로고    scopus 로고
    • Increased levels of ubiquitin in the 6-OHDA-lesioned striatum of rats
    • Pierson, J.; Svenningsson, P.; Caprioli, R. M.; Andren, P. E. Increased levels of ubiquitin in the 6-OHDA-lesioned striatum of rats. J. Proteome Res. 2005, 4 (2), 223-226.
    • (2005) J. Proteome Res , vol.4 , Issue.2 , pp. 223-226
    • Pierson, J.1    Svenningsson, P.2    Caprioli, R.M.3    Andren, P.E.4
  • 30
    • 3342996780 scopus 로고    scopus 로고
    • Molecular profiling of experimental Parkinson's disease: Direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry
    • Pierson, J.; Norris, J. L.; Aerni, H. R.; Svenningsson, P.; Caprioli, R. M.; Andren, P. E. Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry. J. Proteome Res. 2004, 3 (2), 289-295.
    • (2004) J. Proteome Res , vol.3 , Issue.2 , pp. 289-295
    • Pierson, J.1    Norris, J.L.2    Aerni, H.R.3    Svenningsson, P.4    Caprioli, R.M.5    Andren, P.E.6
  • 31
    • 0036747311 scopus 로고    scopus 로고
    • Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry
    • Chaurand, P.; Caprioli, R. M. Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry. Electrophoresis 2002, 23 (18), 3125-3135.
    • (2002) Electrophoresis , vol.23 , Issue.18 , pp. 3125-3135
    • Chaurand, P.1    Caprioli, R.M.2
  • 32
    • 0025818117 scopus 로고
    • Partial lesion of the substantia nigra: Relation between extent of lesion and rotational behavior
    • Carman, L. S.; Gage, F. H.; Shults, C. W. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res. 1991, 553 (2), 275-283.
    • (1991) Brain Res , vol.553 , Issue.2 , pp. 275-283
    • Carman, L.S.1    Gage, F.H.2    Shults, C.W.3
  • 33
    • 0025140557 scopus 로고
    • Autoradiographic localization of cocaine binding sites by [3H]-CFT ([3H]WIN 35,428) in the monkey brain
    • Canfield, D. R.; Spealman, R. D.; Kaufman, M. J.; Madras, B. K. Autoradiographic localization of cocaine binding sites by [3H]-CFT ([3H]WIN 35,428) in the monkey brain. Synapse 1990, 6 (2), 189-195.
    • (1990) Synapse , vol.6 , Issue.2 , pp. 189-195
    • Canfield, D.R.1    Spealman, R.D.2    Kaufman, M.J.3    Madras, B.K.4
  • 34
    • 0030614931 scopus 로고    scopus 로고
    • Comparative evaluation of [3H]WIN 35428 and [3H]GBR 12935 as markers of dopamine innervation density in brain
    • Soucy, J. P.; Mrini, A.; Lafaille, F.; Doucet, G.; Descarries, L. Comparative evaluation of [3H]WIN 35428 and [3H]GBR 12935 as markers of dopamine innervation density in brain. Synapse 1997, 25 (2), 163-175.
    • (1997) Synapse , vol.25 , Issue.2 , pp. 163-175
    • Soucy, J.P.1    Mrini, A.2    Lafaille, F.3    Doucet, G.4    Descarries, L.5
  • 35
    • 0028843879 scopus 로고
    • Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux
    • Cameron, A. M.; Steiner, J. P.; Roskams, A. J.; Ali, S. M.; Ronnettt, G. V.; Snyder, S. H. Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux. Cell 1995, 83 (3), 463-472.
    • (1995) Cell , vol.83 , Issue.3 , pp. 463-472
    • Cameron, A.M.1    Steiner, J.P.2    Roskams, A.J.3    Ali, S.M.4    Ronnettt, G.V.5    Snyder, S.H.6
  • 36
    • 0036951854 scopus 로고    scopus 로고
    • Immunophilins and their ligands: Insights into survival and growth of human neurons
    • Avramut, M.; Achim, C. L. Immunophilins and their ligands: insights into survival and growth of human neurons. Physiol. Behav. 2002, 77 (4-5), 463-468.
    • (2002) Physiol. Behav , vol.77 , Issue.4-5 , pp. 463-468
    • Avramut, M.1    Achim, C.L.2
  • 37
    • 0022539191 scopus 로고    scopus 로고
    • Skene, J. H.; Jacobson, R. D.; Snipes, G. J.; McGuire, C. B.; Norden, J. J.; Freeman, J. A. A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes. Science 1986, 233 (4765), 783-786.
    • Skene, J. H.; Jacobson, R. D.; Snipes, G. J.; McGuire, C. B.; Norden, J. J.; Freeman, J. A. A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes. Science 1986, 233 (4765), 783-786.
  • 38
    • 0028956418 scopus 로고
    • Neuronal regeneration enhances the expression of the immunophilin FKBP- 12
    • Lyons, W.; Steiner, J.; Snyder, S.; Dawson, T. Neuronal regeneration enhances the expression of the immunophilin FKBP- 12. J. Neurosci. 1995, 15 (4), 2985-2994.
    • (1995) J. Neurosci , vol.15 , Issue.4 , pp. 2985-2994
    • Lyons, W.1    Steiner, J.2    Snyder, S.3    Dawson, T.4
  • 39
    • 0037072537 scopus 로고    scopus 로고
    • Induced expression of early response genes/ oxidative injury in rat pheochromocytoma (PC12) cell line by 6-hydroxydopamine: Implication for Parkinson's disease
    • Seth, K.; Agrawal, A. K.; Aziz, M. H.; Ahmad, A.; Shukla, Y.; Mathur, N.; Seth, P. K. Induced expression of early response genes/ oxidative injury in rat pheochromocytoma (PC12) cell line by 6-hydroxydopamine: implication for Parkinson's disease. Neurosci. Lett. 2002, 330 (1), 89-93.
    • (2002) Neurosci. Lett , vol.330 , Issue.1 , pp. 89-93
    • Seth, K.1    Agrawal, A.K.2    Aziz, M.H.3    Ahmad, A.4    Shukla, Y.5    Mathur, N.6    Seth, P.K.7
  • 40
    • 3242813744 scopus 로고    scopus 로고
    • Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation
    • Shen, Y.; Mani, S.; Meiri, K. F. Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation. Mol. Cell. Neurosci. 2004, 26 (3), 390-405.
    • (2004) Mol. Cell. Neurosci , vol.26 , Issue.3 , pp. 390-405
    • Shen, Y.1    Mani, S.2    Meiri, K.F.3
  • 42
    • 0032169935 scopus 로고    scopus 로고
    • Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: Relevance to Parkinson's disease
    • Merad-Boudia, M.; Nicole, A.; Santiard-Baron, D.; Saille, C.; Ceballos-Picot, I. Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease. Biochem. Pharmacol. 1998, 56 (5), 645-655.
    • (1998) Biochem. Pharmacol , vol.56 , Issue.5 , pp. 645-655
    • Merad-Boudia, M.1    Nicole, A.2    Santiard-Baron, D.3    Saille, C.4    Ceballos-Picot, I.5
  • 43
    • 11844278459 scopus 로고    scopus 로고
    • Redoxing Calcium from the ER
    • Roderick, H. L.; Bootman, M. D. Redoxing Calcium from the ER. Cell 2005, 120 (1), 4-5.
    • (2005) Cell , vol.120 , Issue.1 , pp. 4-5
    • Roderick, H.L.1    Bootman, M.D.2
  • 44
    • 0027937548 scopus 로고
    • Oxidative stress: Free radical production in neural degeneration
    • Gotz, M. E.; Kunig, G.; Riederer, P.; Youdim, M. B., Oxidative stress: free radical production in neural degeneration. Pharmacol. Ther. 1994, 63 (1), 37-122.
    • (1994) Pharmacol. Ther , vol.63 , Issue.1 , pp. 37-122
    • Gotz, M.E.1    Kunig, G.2    Riederer, P.3    Youdim, M.B.4
  • 45
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn, S.; Cohen, G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 1992, 32 (6), 804-812.
    • (1992) Ann. Neurol , vol.32 , Issue.6 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 46
    • 33646708957 scopus 로고    scopus 로고
    • Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis
    • Poon, H. F.; Shepherd, H. M.; Reed, T. T.; Calabrese, V.; Stella, A. M.; Pennisi, G.; Cai, J.; Pierce, W. M.; Klein, J. B.; Butterfield, D. A. Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis. Neurobiol. Aging 2006, 27 (7), 1020-1034.
    • (2006) Neurobiol. Aging , vol.27 , Issue.7 , pp. 1020-1034
    • Poon, H.F.1    Shepherd, H.M.2    Reed, T.T.3    Calabrese, V.4    Stella, A.M.5    Pennisi, G.6    Cai, J.7    Pierce, W.M.8    Klein, J.B.9    Butterfield, D.A.10
  • 48
    • 0033621880 scopus 로고    scopus 로고
    • 14-3-3tau associates with a translational control factor FKBP12-rapamycin-associated protein in T-cells after stimulation by pervanadate
    • Mori, H.; Inoue, M.; Yano, M.; Wakabayashi, H.; Kido, H., 14-3-3tau associates with a translational control factor FKBP12-rapamycin-associated protein in T-cells after stimulation by pervanadate. FEBS Lett. 2000, 467 (1), 61-64.
    • (2000) FEBS Lett , vol.467 , Issue.1 , pp. 61-64
    • Mori, H.1    Inoue, M.2    Yano, M.3    Wakabayashi, H.4    Kido, H.5
  • 49
    • 19444378365 scopus 로고    scopus 로고
    • 14-3-3 and calmodulin control subcellular distribution of Kir/Gem and its regulation of cell shape and calcium channel activity
    • Beguin, P.; Mahalakshmi, R. N.; Nagashima, K.; Cher, D. H.; Takahashi, A.; Yamada, Y.; Seino, Y.; Hunziker, W. 14-3-3 and calmodulin control subcellular distribution of Kir/Gem and its regulation of cell shape and calcium channel activity. J. Cell Sci. 2005, 118, (Pt 9), 1923-1934.
    • (2005) J. Cell Sci , vol.118 , Issue.PART 9 , pp. 1923-1934
    • Beguin, P.1    Mahalakshmi, R.N.2    Nagashima, K.3    Cher, D.H.4    Takahashi, A.5    Yamada, Y.6    Seino, Y.7    Hunziker, W.8
  • 50
    • 0027333423 scopus 로고
    • Role of the major heat shock proteins as molecular chaperones
    • Georgopoulos, C.; Welch, W. J. Role of the major heat shock proteins as molecular chaperones. Annu. Rev. Cell Biol. 1993, 9, 601-634.
    • (1993) Annu. Rev. Cell Biol , vol.9 , pp. 601-634
    • Georgopoulos, C.1    Welch, W.J.2
  • 52
    • 0025877838 scopus 로고
    • Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatases
    • Takai, A.; Mieskes, G., Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatases. Biochem. J. 1991, 275 (Pt 1), 233-239.
    • (1991) Biochem. J , vol.275 , Issue.PART 1 , pp. 233-239
    • Takai, A.1    Mieskes, G.2
  • 53
    • 0026739438 scopus 로고
    • Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system
    • Hutchinson, K. A.; Brott, B. K.; De Leon, J. H.; Perdew, G. H.; Jove, R.; Pratt, W. B. Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system. J. Biol. Chem. 1992, 267 (5), 2902-2908.
    • (1992) J. Biol. Chem , vol.267 , Issue.5 , pp. 2902-2908
    • Hutchinson, K.A.1    Brott, B.K.2    De Leon, J.H.3    Perdew, G.H.4    Jove, R.5    Pratt, W.B.6
  • 54
    • 0026730719 scopus 로고
    • Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein
    • Massol, N.; Lebeau, M. C.; Renoir, J. M.; Faber, L. E.; Baulieu, E. E. Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein. Biochem. Biophys. Res. Commun. 1992, 187 (3), 1330-1335.
    • (1992) Biochem. Biophys. Res. Commun , vol.187 , Issue.3 , pp. 1330-1335
    • Massol, N.1    Lebeau, M.C.2    Renoir, J.M.3    Faber, L.E.4    Baulieu, E.E.5
  • 55
    • 0028957401 scopus 로고
    • Evidence for a functional interaction between calmodulin and the glucocorticoid receptor
    • Ning, Y. M.; Sanchez, E. R. Evidence for a functional interaction between calmodulin and the glucocorticoid receptor. Biochem. Biophys. Res. Commun. 1995, 208 (1), 48-54.
    • (1995) Biochem. Biophys. Res. Commun , vol.208 , Issue.1 , pp. 48-54
    • Ning, Y.M.1    Sanchez, E.R.2
  • 56
    • 0033554044 scopus 로고    scopus 로고
    • Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms
    • Someren, J. S.; Faber, L. E.; Klein, J. D.; Tumlin, J. A. Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms. Biochem. Biophys. Res. Commun. 1999, 260 (3), 619-625.
    • (1999) Biochem. Biophys. Res. Commun , vol.260 , Issue.3 , pp. 619-625
    • Someren, J.S.1    Faber, L.E.2    Klein, J.D.3    Tumlin, J.A.4
  • 57
    • 13844266044 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide
    • Lovell, M. A.; Xiong, S.; Markesbery, W. R.; Lynn, B. C. Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide. Neurochem. Res. 2005, 30 (1), 113-122.
    • (2005) Neurochem. Res , vol.30 , Issue.1 , pp. 113-122
    • Lovell, M.A.1    Xiong, S.2    Markesbery, W.R.3    Lynn, B.C.4
  • 61
    • 0036224579 scopus 로고    scopus 로고
    • Skold, K.; Svensson, M.; Kaplan, A.; Bjorkesten, L.; Astrom, J.; Andren, P. E. A neuroproteomic approach to targeting neuropeptides in the brain. Proteomics 2002, 2 (4), 447-454.
    • Skold, K.; Svensson, M.; Kaplan, A.; Bjorkesten, L.; Astrom, J.; Andren, P. E. A neuroproteomic approach to targeting neuropeptides in the brain. Proteomics 2002, 2 (4), 447-454.


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