PF1022A - A novel anthelmintic cyclooctadepsipeptide. Modification and exchange of the N-methyl leucine residues

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 9, 1998, Pages 1035-1040

  Scherkenbreck, Jürgen ^a   Harder, Achim ^b   Plant, Andrew ^b   Dyker, Hubert ^a  

^a Central Research   (Germany)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(DEXTRO LACTYL N METHYLLEUCYL DEXTRO 3 PHENYLLACTYL N METHYLLEUCYL DEXTRO LACTYL N METHYLLEUCYL DEXTRO 3 PHENYLLACTYL N METHYLLEUCYL); CYCLODEPSIPEPTIDE; LEUCINE; UNCLASSIFIED DRUG;

ANTHELMINTIC ACTIVITY; ARTICLE; DRUG POTENCY; ENZYME MODIFICATION; GASTROINTESTINAL INFECTION; LIPOPHILICITY; NEMATODE; NONHUMAN; PROTEIN MODIFICATION; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION;

ALKYLATION; AMINO ACIDS; ANIMALS; ANTHELMINTICS; DEPSIPEPTIDES; DRUG DESIGN; FECES; HAEMONCHIASIS; HAEMONCHUS; LEUCINE; MOLECULAR STRUCTURE; PARASITE EGG COUNT; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; SHEEP; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17544395284     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00156-5     Document Type: Article

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