-
1
-
-
81855206508
-
Novel therapies for metastatic castrate-resistant prostate cancer
-
Review
-
Dayyani F, Gallick GE, Logothetis CJ and Corn PG: Novel therapies for metastatic castrate-resistant prostate cancer (Review). J Natl Cancer Inst 103: 1665-1675, 2011.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1665-1675
-
-
Dayyani, F.1
Gallick, G.E.2
Logothetis, C.J.3
Corn, P.G.4
-
2
-
-
49249123274
-
Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer
-
Eisermann K, Tandon S, Bazarov A, Brett A, Fraizer G and Piontkivska H: Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer. BMC Genomics 9: 337, 2008.
-
(2008)
BMC Genomics
, vol.9
, pp. 337
-
-
Eisermann, K.1
Tandon, S.2
Bazarov, A.3
Brett, A.4
Fraizer, G.5
Piontkivska, H.6
-
3
-
-
34249798732
-
Transcription factors: Molecular targets for prostate cancer intervention by phytochemicals
-
DOI 10.2174/156800907780809732
-
Kaur M and Agarwal R: Transcription factors: molecular targets for prostate cancer intervention by phytochemicals (Review). Curr Cancer Drug Targets 7: 355-367, 2007. (Pubitemid 46849240)
-
(2007)
Current Cancer Drug Targets
, vol.7
, Issue.4
, pp. 355-367
-
-
Kaur, M.1
Agarwal, R.2
-
4
-
-
68849096495
-
Anti-inflammatory drugs, antioxidants, and prostate cancer prevention
-
Review
-
Bardia A, Platz EA, Yegnasubramanian S, De Marzo AM and Nelson WG: Anti-inflammatory drugs, antioxidants, and prostate cancer prevention (Review). Curr Opin Pharmacol 9: 419-426, 2009.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 419-426
-
-
Bardia, A.1
Platz, E.A.2
Yegnasubramanian, S.3
De Marzo, A.M.4
Nelson, W.G.5
-
5
-
-
67349136004
-
Mcl-1 is a potential therapeutic target in multiple types of cancer
-
Review
-
Akgul C: Mcl-1 is a potential therapeutic target in multiple types of cancer (Review). Cell Mol Life Sci 66: 1326-1336, 2009.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 1326-1336
-
-
Akgul, C.1
-
6
-
-
80054008573
-
Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263
-
Tang H, Shao H, Yu C and Hou J: Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263. Biochem Pharmacol 82: 1066-1072, 2011.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1066-1072
-
-
Tang, H.1
Shao, H.2
Yu, C.3
Hou, J.4
-
7
-
-
80052920610
-
Probing the difference between BH3 groove of Mcl-1 and Bcl-2 protein: Implications for dual inhibitors design
-
Zhang Z, Yang H, Wu G, Li Z, Song T and Li XQ: Probing the difference between BH3 groove of Mcl-1 and Bcl-2 protein: Implications for dual inhibitors design. Eur J Med Chem 46: 3909-3916, 2011.
-
(2011)
Eur J Med Chem
, vol.46
, pp. 3909-3916
-
-
Zhang, Z.1
Yang, H.2
Wu, G.3
Li, Z.4
Song, T.5
Li, X.Q.6
-
8
-
-
42049091619
-
Unique biology of Mcl-1: Therapeutic oportunities in cancer
-
DOI 10.2174/156652408783769580
-
Warr MR and Shore GC: Unique biology of Mcl-1: therapeutic opportunities in cancer (Review). Curr Mol Med 8: 138-147, 2008. (Pubitemid 351516833)
-
(2008)
Current Molecular Medicine
, vol.8
, Issue.2
, pp. 138-147
-
-
Warr, M.R.1
Shore, G.C.2
-
9
-
-
79959364228
-
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 downregulation in human pancreatic cancer cells
-
Takahashi H, Chen MC, Pham H, et al: Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 downregulation in human pancreatic cancer cells. Biochim Biophys Acta 1813: 1465-1474, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1465-1474
-
-
Takahashi, H.1
Chen, M.C.2
Pham, H.3
-
10
-
-
77149128046
-
Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis
-
Chen W, Bai L, Wang X, Xu S, Belinsky SA and Lin Y: Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis. Mol Pharmacol 77: 416-423, 2010.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 416-423
-
-
Chen, W.1
Bai, L.2
Wang, X.3
Xu, S.4
Belinsky, S.A.5
Lin, Y.6
-
11
-
-
51849157031
-
Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell
-
Wei SH, Dong K, Lin F, et al: Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. Cancer Chemother Pharmacol 62: 1055-1064, 2008.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 1055-1064
-
-
Wei, S.H.1
Dong, K.2
Lin, F.3
-
12
-
-
33750051632
-
Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
-
Schulze-Bergkamen H, Fleischer B, Schuchmann M, et al: Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. BMC Cancer 6: 232, 2006.
-
(2006)
BMC Cancer
, vol.6
, pp. 232
-
-
Schulze-Bergkamen, H.1
Fleischer, B.2
Schuchmann, M.3
-
13
-
-
77949490478
-
Adenovirus-mediated siRNA targeting Mcl-1 gene increases radiosensitivity of pancreatic carcinoma cells in vitro and in vivo
-
Guoan X, Hanning W, Kaiyun C and Hao L: Adenovirus-mediated siRNA targeting Mcl-1 gene increases radiosensitivity of pancreatic carcinoma cells in vitro and in vivo. Surgery 147: 553-561, 2010.
-
(2010)
Surgery
, vol.147
, pp. 553-561
-
-
Guoan, X.1
Hanning, W.2
Kaiyun, C.3
Hao, L.4
-
14
-
-
75649113906
-
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
-
Bredholt T, Dimba EA, Hagland HR, et al: Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. Mol Cancer 8: 101, 2009.
-
(2009)
Mol Cancer
, vol.8
, pp. 101
-
-
Bredholt, T.1
Dimba, E.A.2
Hagland, H.R.3
-
15
-
-
79957447905
-
Effect of Orostachys japonicus on cell growth and apoptosis in human hepatic stellate cell line LX2
-
Kim YI, Park SW, Choi IH, Lee JH, Woo HJ and Kim Y: Effect of Orostachys japonicus on cell growth and apoptosis in human hepatic stellate cell line LX2. Am J Chin Med 39: 601-613, 2011.
-
(2011)
Am J Chin Med
, vol.39
, pp. 601-613
-
-
Kim, Y.I.1
Park, S.W.2
Choi, I.H.3
Lee, J.H.4
Woo, H.J.5
Kim, Y.6
-
16
-
-
77955730487
-
Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model
-
Lee NH, Lee MY, Lee JA, et al: Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model. Int J Mol Med 26: 201-208, 2010.
-
(2010)
Int J Mol Med
, vol.26
, pp. 201-208
-
-
Lee, N.H.1
Lee, M.Y.2
Lee, J.A.3
-
17
-
-
33845245421
-
The inhibitory effect of triterpenoid glycosides originating from Sanguisorba officinalis on tissue factor activity and the production of TNF-alpha
-
Cho JY, Yoo ES, Cha BC, Park HJ, Rhee MH and Han YN: The inhibitory effect of triterpenoid glycosides originating from Sanguisorba officinalis on tissue factor activity and the production of TNF-alpha. Planta Med 72: 1279-1284, 2006.
-
(2006)
Planta Med
, vol.72
, pp. 1279-1284
-
-
Cho, J.Y.1
Yoo, E.S.2
Cha, B.C.3
Park, H.J.4
Rhee, M.H.5
Han, Y.N.6
-
18
-
-
0035996867
-
Anticancer and antithrombin activity of Russian plants
-
DOI 10.1016/S0378-8741(02)00116-2, PII S0378874102001162
-
Goun EA, Petrichenko VM, Solodnikov SU, et al: Anticancer and antithrombin activity of Russian plants. J Ethnopharmacol 81: 337-342, 2002. (Pubitemid 34786318)
-
(2002)
Journal of Ethnopharmacology
, vol.81
, Issue.3
, pp. 337-342
-
-
Goun, E.A.1
Petrichenko, V.M.2
Solodnikov, S.U.3
Suhinina, T.V.4
Kline, M.A.5
Cunningham, G.6
Nguyen, C.7
Miles, H.8
-
19
-
-
84862825477
-
A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells
-
Ma Y, Zhang A, Shi Z, et al: A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells. Toxicol In Vitro 26: 414-420, 2012.
-
(2012)
Toxicol in Vitro
, vol.26
, pp. 414-420
-
-
Ma, Y.1
Zhang, A.2
Shi, Z.3
-
20
-
-
80052674065
-
Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo
-
Wang X, Zhang F, Yang L, et al: Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo. J Biomed Biotechnol 2011: 419343, 2011.
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 419343
-
-
Wang, X.1
Zhang, F.2
Yang, L.3
-
21
-
-
79953772398
-
Honokiol: A promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells
-
Chen XR, Lu R, Dan HX, et al: Honokiol: a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells. Int J Oral Sci 3: 34-42, 2011.
-
(2011)
Int J Oral Sci
, vol.3
, pp. 34-42
-
-
Chen, X.R.1
Lu, R.2
Dan, H.X.3
-
22
-
-
79957982942
-
Natural plant extract tubeimoside I promotes apoptosis-mediated cell death in cultured human hepatoma (HepG2) cells
-
Wang Y, Deng L, Zhong H, Jiang X and Chen J: Natural plant extract tubeimoside I promotes apoptosis-mediated cell death in cultured human hepatoma (HepG2) cells. Biol Pharm Bull 34: 831-838, 2011.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 831-838
-
-
Wang, Y.1
Deng, L.2
Zhong, H.3
Jiang, X.4
Chen, J.5
-
23
-
-
79952838142
-
Andrographolide, a herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth
-
Chun JY, Tummala R, Nadiminty N, et al: Andrographolide, a herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth. Genes Cancer 1: 868-876, 2010.
-
(2010)
Genes Cancer
, vol.1
, pp. 868-876
-
-
Chun, J.Y.1
Tummala, R.2
Nadiminty, N.3
-
24
-
-
80052771756
-
Coprescription of Chinese herbal medicine and western medications among prostate cancer patients: A population-based study in Taiwan
-
Lin YH, Chen KK and Chiu JH: Coprescription of Chinese herbal medicine and western medications among prostate cancer patients: a population-based study in Taiwan. Evid Based Complement Alternat Med 2012: 147015, 2012.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 147015
-
-
Lin, Y.H.1
Chen, K.K.2
Chiu, J.H.3
-
25
-
-
84863260112
-
Effect of Sanguisorba officinalis L. on breast cancer growth and angiogenesis
-
Wang Z, Loo WT, Wang N, Chow LW, Wang D, Han F, Zheng X and Chen JP: Effect of Sanguisorba officinalis L. on breast cancer growth and angiogenesis. Expert Opin Ther Targets 16 (Suppl 1): S79-S89, 2012.
-
(2012)
Expert Opin Ther Targets
, vol.16
, Issue.SUPPL. 1
-
-
Wang, Z.1
Loo, W.T.2
Wang, N.3
Chow, L.W.4
Wang, D.5
Han, F.6
Zheng, X.7
Chen, J.P.8
-
26
-
-
80052777525
-
Targeting Mcl-1 for the therapy of cancer
-
Review
-
Quinn BA, Dash R, Azab B, et al: Targeting Mcl-1 for the therapy of cancer (Review). Expert Opin Investig Drugs 20: 1397-1411, 2011.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 1397-1411
-
-
Quinn, B.A.1
Dash, R.2
Azab, B.3
-
27
-
-
79957689156
-
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity
-
Dash R, Azab B, Quinn BA, et al: Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proc Natl Acad Sci USA 108: 8785-8790, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 8785-8790
-
-
Dash, R.1
Azab, B.2
Quinn, B.A.3
-
28
-
-
84856196328
-
Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1
-
Senft D, Berking C, Graf SA, Kammerbauer C, Ruzicka T and Besch R: Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. PLoS One 7: e30821, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Senft, D.1
Berking, C.2
Graf, S.A.3
Kammerbauer, C.4
Ruzicka, T.5
Besch, R.6
-
29
-
-
34247254266
-
L and activates BAK-mediated apoptosis in response to protein synthesis inhibition
-
DOI 10.1101/gad.1522007
-
Shimazu T, Degenhardt K, Nur-E-Kamal A, et al: NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition. Genes Dev 21: 929-941, 2007. (Pubitemid 46625642)
-
(2007)
Genes and Development
, vol.21
, Issue.8
, pp. 929-941
-
-
Shimazu, T.1
Degenhardt, K.2
Nur-E-Kamal, A.3
Zhang, J.4
Yoshida, T.5
Zhang, Y.6
Mathew, R.7
White, E.8
Inouye, M.9
-
30
-
-
70350025502
-
Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis
-
Dewson G and Kluck RM: Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis. J Cell Sci 122: 2801-2808, 2009.
-
(2009)
J Cell Sci
, vol.122
, pp. 2801-2808
-
-
Dewson, G.1
Kluck, R.M.2
-
31
-
-
33751513394
-
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
-
DOI 10.1038/ncb1499, PII NCB1499
-
Kim H, Rafiuddin-Shah M, Tu HC, et al: Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell Biol 8: 1348-1358, 2006. (Pubitemid 44835109)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.12
, pp. 1348-1358
-
-
Kim, H.1
Rafiuddin-Shah, M.2
Tu, H.-C.3
Jeffers, J.R.4
Zambetti, G.P.5
Hsieh, J.J.-D.6
Cheng, E.H.-Y.7
-
32
-
-
33646846666
-
Mcl-1 interacts with truncated bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis
-
DOI 10.1074/jbc.M505688200
-
Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G and Brady HJ: Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. J Biol Chem 281: 5750-5759, 2006. (Pubitemid 43847674)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.9
, pp. 5750-5759
-
-
Clohessy, J.G.1
Zhuang, J.2
De Boer, J.3
Gil-Gomez, G.4
Brady, H.J.M.5
-
33
-
-
34748924281
-
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
-
DOI 10.1016/j.coi.2007.05.004, PII S0952791507000994, Hematopoietic cell death/Immunogenetics/Transplantation
-
Adams JM and Cory S: Bcl-2-regulated apoptosis: mechanism and therapeutic potential (Review). Curr Opin Immunol 19: 488-496, 2007. (Pubitemid 47487452)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.5
, pp. 488-496
-
-
Adams, J.M.1
Cory, S.2
-
34
-
-
78549257149
-
Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo
-
Mitchell C, Yacoub A, Hossein H, et al: Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. Cancer Biol Ther 10: 903-917, 2010.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 903-917
-
-
Mitchell, C.1
Yacoub, A.2
Hossein, H.3
-
35
-
-
74449084885
-
Mcl-1(128-350) fragment induces apoptosis through direct interaction with Bax
-
Ménoret E, Gomez-Bougie P, Surget S, et al: Mcl-1(128-350) fragment induces apoptosis through direct interaction with Bax. FEBS Lett 584: 487-492, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 487-492
-
-
Ménoret, E.1
Gomez-Bougie, P.2
Surget, S.3
-
36
-
-
69249139451
-
Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax
-
Jiang CC, Wroblewski D, Yang F, Hersey P and Zhang XD: Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax. Neoplasia 11: 945-955, 2009.
-
(2009)
Neoplasia
, vol.11
, pp. 945-955
-
-
Jiang, C.C.1
Wroblewski, D.2
Yang, F.3
Hersey, P.4
Zhang, X.D.5
-
37
-
-
32644473650
-
How the Bcl-2 family of proteins interact to regulate apoptosis
-
Review
-
van Delft MF and Huang DC: How the Bcl-2 family of proteins interact to regulate apoptosis (Review). Cell Res 16: 203-213, 2006.
-
(2006)
Cell Res
, vol.16
, pp. 203-213
-
-
Van Delft, M.F.1
Huang, D.C.2
-
38
-
-
0142027948
-
Ways of dying: Multiple pathways to apoptosis
-
Adams JM: Ways of dying: multiple pathways to apoptosis. Genes Dev 17: 2481-2495, 2003.
-
(2003)
Genes Dev
, vol.17
, pp. 2481-2495
-
-
Adams, J.M.1
-
39
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
DOI 10.1126/science.1099320
-
Green DR and Kroemer G: The pathophysiology of mitochondrial cell death (Review). Science 305: 626-629, 2004. (Pubitemid 39006738)
-
(2004)
Science
, vol.305
, Issue.5684
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
40
-
-
65749090235
-
Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis
-
Chu R, Upreti M, Ding WX, Yin XM and Chambers TC: Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis. Biochem Pharmacol 78: 241-248, 2009.
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 241-248
-
-
Chu, R.1
Upreti, M.2
Ding, W.X.3
Yin, X.M.4
Chambers, T.C.5
-
41
-
-
19844374460
-
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells
-
DOI 10.1093/carcin/bgi040
-
Qanungo S, Das M, Haldar S and Basu A: Epigallocatechin- 3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells. Carcinogenesis 26: 958-967, 2005. (Pubitemid 41214325)
-
(2005)
Carcinogenesis
, vol.26
, Issue.5
, pp. 958-967
-
-
Qanungo, S.1
Das, M.2
Haldar, S.3
Basu, A.4
-
42
-
-
84862917028
-
Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule
-
Zhao L, He F, Liu H, et al: Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule. J Biol Chem 287: 1054-1065, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 1054-1065
-
-
Zhao, L.1
He, F.2
Liu, H.3
|