Natural plant extract tubeimoside I promotes apoptosis-mediated cell death in cultured human hepatoma (HepG2) cells

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 6, 2011, Pages 831-838

  Wang, Yashu ^a   Deng, Linhong ^a   Zhong, Hongzhe ^b   Wang, Yajie ^c   Jiang, Xuemei ^a   Chen, Jun ^a  

^a CHONGQING UNIVERSITY   (China)

^b Liaoning Blood Center   (China)

^c No 324 Hospital of People's Liberation Army   (China)

Author keywords

Apoptosis; Cytotoxicity; Hepatoma HepG2 cell line; Mitochondrial dysfunction; Tubeimoside I

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; TUBEIMOSIDE I; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CUCUMBER; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; HEPATOMA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE; MITOSIS INHIBITION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL NUCLEUS SHAPE; CELL PROLIFERATION; CELL SIZE; DRUGS, CHINESE HERBAL; G2 PHASE; HEP G2 CELLS; HEPATOCYTES; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROTUBULES; MITOCHONDRIA, LIVER; SAPONINS; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 79957982942     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.831     Document Type: Article

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