Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation

Endocrinology

Volumn 145, Issue 11, 2004, Pages 4853-4865

  Sbrissa, Diego ^a   Ikonomov, Ognian C ^a   Strakova, Jana ^a   Shisheva, Assia ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; GLUCOSE TRANSPORTER 4; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INSULIN; INSULIN RECEPTOR; PHALLOIDIN; PHOSPHATE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; UNCLASSIFIED DRUG; WORTMANNIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL FUNCTION; CELL SURFACE; CELL TYPE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GLUCOSE TRANSPORT; HORMONAL REGULATION; HORMONE ACTION; INSULIN METABOLISM; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SIGNAL TRANSDUCTION; STRESS FIBER; TIME SERIES ANALYSIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ACTINS; ADIPOCYTES; ANIMALS; CHO CELLS; CRICETINAE; GLUCOSE TRANSPORTER TYPE 4; INSULIN; MICE; MICROINJECTIONS; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STRESS FIBERS;

EID: 8644279885     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0489     Document Type: Article

References (53)

1. Martin TFJ 1998 Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking. Annu Rev Cell Dev Biol 14:231-264
2. Rameh LE, Cantley LC 1999 The role of phosphoinositide 3-kinase lipid products in cell function. J Biol Chem 274:8347-8350
3. Corvera S, Czech MP 1999 Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction. Trends Cell Biol 8:442-446
4. Majerus PW, Kiselleva MV, Norris FA 1999 The role of phosphatases in inositol signaling reactions. J Biol Chem 274:10669-10672
5. Czech MP 2000 PIP2 and PIP3: complex roles at the cell surface. Cell 100: 603-606
6. York JD, Guo S, Odom AR, Spiegelberg BR, Stolz LE 2001 An expanded view of inositol signaling. Adv Enzyme Regul 41:57-71
7. Shisheva A 2003 Regulating GLUT4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases. Front Biosci 8:s945-s967
8. Yin HL, Janmey PA 2003 Phosphoinositide regulation of the actin cytoskeleton. Annu Rev Physiol 65:761-789
9. Odorizzi G, Babst M, Emr SD 2000 Phosphoinositide signaling and the regulation of membrane trafficking in yeast. Trends Biochem Sci 25:229-234
10. Hurley JH, Meyer T 2001 Phoxy lipids: revealing PX domains as phosphoinositide binding modules. Subcellular targeting by membrane lipids. Curr Opin Cell Biol 13:146-152
11. Wishart MJ, Taylor GS, Dixon JE 2001 Phoxy lipids: revealing PX domains as phosphoinositide binding modules. Cell 105:817-820
12. Stenmark H, Aaasland R, Driscoll PC 2002 The phosphatidylinositol 3-phosphate-binding FYVE finger. FEBS Lett 513:77-84
13. Czech MP 2003 Dynamics of phosphoinositides in membrane retrieval and insertion. Annu Rev Physiol 65:791-815
14. Rameh LE, Tolias KF, Duckworth BC, Cantley LC 1997 A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 309:192-196
15. Morris JB, Kinchliffe KA, Ciruela A, Letcher AJ, Irvine RF 2000 Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assay. FEBS Lett 475:57-60
16. Sbrissa D, Ikonomov OC, Deeb R, Shisheva A 2002 Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells. J Biol Chem 277:47276-47284
17. 2 into PtdIns(5)P by the S.flexneri effector 1pgD reorganizes host cell morphology. EMBO J 21:5069-5078
18. Clarke JH, Letcher AJ, D'Santos CR, Irvine RF, Divecha N 2001 Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells. Biochem J 357:905-910
19. Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Willasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J 2003 The PHD finger of the chromatin-associated protein 1NG2 functions as a nuclear phosphoinositide receptor. Cell 114:99-111
20. Czech MP, Corvera S 1999 Signaling mechanisms that regulate glucose transport. J Biol Chem 274:1865-1868
21. Bryant NJ, Govers R, James DE 2002 Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3:267-277
22. Saltiel AR, Pessin JE 2002 Insulin signaling pathways in time and space. Trends Cell Biol 12:65-71
23. Khan A, Pessin J 2002 Insulin regulation of glucose uptake: a complex interplay of intracellular signaling pathways. Diabetologia 45:1475-1483
24. Kanzaki M, Pessin JE 2003 Insulin signaling: GLUT4 vesicles exit via the exocyst. Curr Biol 13:R574-R576
25. Tsakiridis T, Tong P, Matthews B, Tsiani E, Bilan PJ, Klip A, Downey GP 1999 Role of the actin cytoskeleton in insulin action. Microsc Res Tech 47:79-92
26. Omata W, Shibata H, Li L, Takata K, Kojima I 2000 Actin filaments play a critical role in insulin-induced exocytotic recruitment but not in endocytosis of GLUT4 in isolated rat adipocytes. Biochem J 346:321-328
27. Tong P, Khayat ZA, Huang C, Patel N, Ueyama A, Klip A 2001 Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles. J Clin Invest 108:371-381
28. Kanzaki M, Watson RT, Khan AH, Pessin JE 2001 Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes. J Biol Chem 276:49331-49336
29. Kanzaki M, Pessin JE 2001 Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling. J Biol Chem 276:42436-42444
30. Jiang ZY, Chawla A, Bose A, Way M, Czech MP 2002 A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP/Arp2/3/F-actin required for GLUT4 glucose transporter recycling. J Biol Chem 277:509-515
31. Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE 2002 Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. Mol Biol Cell 13:2334-2346
32. Knight JB, Yamauchi K, Pessin JE 1995 Divergent insulin and platelet-derived growth factor regulation of focal adhesion kinase (pp125FAK) tyrosine phosphorylation, and rearrangement of actin stress fibers. J Biol Chem 270:10199-10203
33. Wang Q, Bilan PJ, Klip A 1998 Opposite effects of insulin on focal adhesion proteins in 3T3-L1 adipocytes and in cells overexpressing the insulin receptor. Mol Biol Cell 9:3057-3069
34. Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM 1996 Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown. Endocrinology 137:5045-5054
35. Ikonomov OC, Sbrissa D, Mlak K, Shisheva A 2002 Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects. Endocrinology 143:4742-4754
36. Sbrissa D, Ikonomov OC, Shisheva A 2002 PtdIns-3-P interacting domains in PIKfyve: binding specificity and role in PIKfyve endomembrane localizations. J Biol Chem 277:6073-6079
37. Ikonomov OC, Sbrissa D, Shisheva A 2001 Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve. J Biol Chem 276:26141-26147
38. 2 production for endomembrane integrity. J Biol Chem 277:9206-9211
39. Ikonomov OC, Sbrissa D, Yoshimori T, Cover TL, Shisheva A 2002 PIKfyve kinase and SKD1 AAA ATPase define distinct endocytic compartments. J Biol Chem 277:46785-46790
40. Sbrissa D, Ikonomov O, Shisheva A 1999 PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. J Biol Chem 274: 21589-21597
41. Clodi M, Vollenweider P, Klarlund J, Nakashima N, Martin S, Czech MP, Olef sky JM 1998 Effects of general receptor for phosphoinositides 1 on insulin and insulin-like growth factor I-induced cytoskeletal rearrangement, glucose transporter-4 translocation, and deoxyribonucleic acid synthesis. Endocrinology 139:4984-4990
42. Vollenweider P, Clodi M, Martin SS, Imamura T, Kavanaugh WM, Olefsky JM 1999 An SH2 domain-containing 5′ inositolphosphatase inhibits insulin-induced GLUT4 translocation and growth factor-induced actin filament rearrangement. Mol Cell Biol 19:1081-1091
43. Jiang T, Sweeney G, Rudolf MT, Klip A, Traynor-Kaplan A, Tsien RY 1998 Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:11017-11024
44. Patki V, Buston J, Chawla, A, Lifshitz L, Fogarty K, Carrington W, Tuft R, Corvera S 2001 Insulin action on GLUT4 traffic visualized in single 3T3-L1 adipocytes by using ultra-fast microscopy. Mol Biol Cell 12:129-141
45. Elmendorf JS, Boeglin DJ, Pessin JE 1999 Temporal separation of insulin-stimulated GLUT4/IRAP vesicle plasma membrane docking and fusion in 3T3L1 adipocytes. J Biol Chem 274:37357-37361
46. Karylowski O, Zeigerer A, Cohen A, McGraw TE 2004 GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes. Mol Biol Cell 15:870-882
47. A phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes. Mol Cell Endocrinol 181:35-46
48. Shisheva A, Russin B, Ikonomov OC, DeMarco C, Sbrissa D 2001 Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes. J Biol Chem 276:11859-11869
49. Ridley AJ, Hall A 1992 The small GTP-binding protein ρ regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70:389-399
50. Martin SS, Haruta T, Morris A, Klippel A, Williams LT, Olefsky JM 1996 Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem 271: 17605-17608
51. Emoto M, Langille SE, Czech MP 2001 A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes. J Biol Chem 276:10677-10682
52. Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA 2003 A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem 278:39866-39873
53. 3 degradation. Proc Natl Acad Sci USA 100:9867-9872