-
1
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001;81:741-66.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
2
-
-
0032960305
-
Regulation of amyloid precursor protein cleavage
-
Mills J, Reiner PB. Regulation of amyloid precursor protein cleavage. J Neurochem. 1999;72:443-60.
-
(1999)
J Neurochem
, vol.72
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
3
-
-
1842732209
-
Oligomerization of Alzheimer's b-amyloid within processes and synapses of cultured neurons and brain
-
Takahashi RH. Oligomerization of Alzheimer's b-amyloid within processes and synapses of cultured neurons and brain. J Neurosci. 2004;24:3592-9.
-
(2004)
J Neurosci
, vol.24
, pp. 3592-3599
-
-
Takahashi, R.H.1
-
4
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta-42 are potent central nervous system neurotoxins
-
Lambert MP, Barlow AK, Chromy BA. Diffusible, nonfibrillar ligands derived from Abeta-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci. 1998;95:6448-53.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
-
5
-
-
33645322386
-
KATP channels as molecular sensors of cellular metabolism
-
Nichols CG. KATP channels as molecular sensors of cellular metabolism. Nature. 2006;440:470-6.
-
(2006)
Nature
, vol.440
, pp. 470-476
-
-
Nichols, C.G.1
-
6
-
-
2442664058
-
Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice
-
Sadowski M, Pankiewicz J, Scholtzova H. Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice. J Neuropathol Exp Neurol. 2004;63:418-28.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 418-428
-
-
Sadowski, M.1
Pankiewicz, J.2
Scholtzova, H.3
-
8
-
-
0036591533
-
Acetyl-L-carnitine protects against amyloid-beta neurotoxicity: Roles of oxidative buffering and ATP levels
-
Dhitavat S, Ortiz D, Shea TB. Acetyl-L-carnitine protects against amyloid-beta neurotoxicity: roles of oxidative buffering and ATP levels. Neurochem Res. 2002;27:501-5.
-
(2002)
Neurochem Res
, vol.27
, pp. 501-505
-
-
Dhitavat, S.1
Ortiz, D.2
Shea, T.B.3
-
9
-
-
0033133579
-
In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta peptide(1-42)
-
Yatin SM, Varadarajan S, Link CD. In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta peptide(1-42). Neurobiol Aging. 1999;20:325-30.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 325-330
-
-
Yatin, S.M.1
Varadarajan, S.2
Link, C.D.3
-
10
-
-
44549083447
-
Effect of Abeta1-42 on the subunits of KATP expression in cultured primary rat basal forebrain neurons
-
Ma GZ, Fu QX, Zhang Y, Gao JX, Jiang JJ, Bi AL, et al. Effect of Abeta1-42 on the subunits of KATP expression in cultured primary rat basal forebrain neurons. Neurochem Res. 2008;33:1419-24.
-
(2008)
Neurochem Res
, vol.33
, pp. 1419-1424
-
-
Ma, G.Z.1
Fu, Q.X.2
Zhang, Y.3
Gao, J.X.4
Jiang, J.J.5
Bi, A.L.6
-
11
-
-
0034612075
-
A selective defect of cytochrome C oxidase is present in brain of Alzheimer's disease patients
-
Maurer I, Zierz S, Moller HJ. A selective defect of cytochrome C oxidase is present in brain of Alzheimer's disease patients. Neurobiol Aging. 2000;21:455-62.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 455-462
-
-
Maurer, I.1
Zierz, S.2
Moller, H.J.3
-
12
-
-
34250705186
-
The mitochondrial permeability transition in neurologic disease
-
Norenberg MD, Rao KV. The mitochondrial permeability transition in neurologic disease. Neurochem Int. 2007;50:983-997.
-
(2007)
Neurochem Int
, vol.50
, pp. 983-997
-
-
Norenberg, M.D.1
Rao, K.V.2
-
13
-
-
0032902145
-
Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis
-
Kruman II, Mattson MP. Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis. J Neurochem. 1999;72:529-40.
-
(1999)
J Neurochem
, vol.72
, pp. 529-540
-
-
Kruman, I.I.1
Mattson, M.P.2
-
14
-
-
37249047093
-
2+-dependent generation ofmitochondrial reactive oxygen species serves as a signal for poly (ADP-ribose) polymerase-1 activation during glutamate excitotoxicity
-
2+-dependent generation ofmitochondrial reactive oxygen species serves as a signal for poly (ADP-ribose) polymerase-1 activation during glutamate excitotoxicity. J Physiol. 2007;585:741-58.
-
(2007)
J Physiol
, vol.585
, pp. 741-758
-
-
Duan, Y.1
Gross, R.A.2
Sheu, S.S.3
-
15
-
-
0035823614
-
Identification and properties of a novel intracellular (mitochondria1) ATP sensitive potassium channel in brain
-
Bajgar R, Seetharaman S, Kowaltowski AJ. Identification and properties of a novel intracellular (mitochondria1) ATP sensitive potassium channel in brain. J Biol Chem. 2001;276:33369-74.
-
(2001)
J Biol Chem
, vol.276
, pp. 33369-33374
-
-
Bajgar, R.1
Seetharaman, S.2
Kowaltowski, A.J.3
-
16
-
-
0036209260
-
Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome C release
-
Liu D, Lu C, Wan R, Auyeung WW, Mattson MP. Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome C release. J Cereb Blood Flow Metab. 2002;22:431-43.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 431-443
-
-
Liu, D.1
Lu, C.2
Wan, R.3
Auyeung, W.W.4
Mattson, M.P.5
-
18
-
-
78650844057
-
The KATP channel activator diazoxide ameliorates amyloid-beta and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease
-
Liu D, Pitta M, Lee JH, Ray B, Lahiri DK, Furukawa K, et al. The KATP channel activator diazoxide ameliorates amyloid-beta and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease. J Alzheimers Dis. 2010;22:443-57.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 443-457
-
-
Liu, D.1
Pitta, M.2
Lee, J.H.3
Ray, B.4
Lahiri, D.K.5
Furukawa, K.6
-
19
-
-
0034683225
-
Potassium channel openers prevent beta-amyloid toxicity in bovine vascular endothelial cells
-
Chi X, Sutton ET, Hellermann G, Price JM. Potassium channel openers prevent beta-amyloid toxicity in bovine vascular endothelial cells. Neurosci Lett. 2000;290:9-12.
-
(2000)
Neurosci Lett
, vol.290
, pp. 9-12
-
-
Chi, X.1
Sutton, E.T.2
Hellermann, G.3
Price, J.M.4
-
20
-
-
4043109284
-
1-42-induced cytotoxicity
-
1-42-induced cytotoxicity. Neuroreport. 2004;15: 1813-7.
-
(2004)
Neuroreport
, vol.15
, pp. 1813-1817
-
-
Ma, G.Z.1
Chen, S.D.2
-
21
-
-
33645899316
-
Role of astrocytes in glutamate homeostasis: Implications for excitotoxicity
-
Schousboe A, Waagepetersen HS. Role of astrocytes in glutamate homeostasis: implications for excitotoxicity. Neurotox Res. 2005;8:221-5.
-
(2005)
Neurotox Res
, vol.8
, pp. 221-225
-
-
Schousboe, A.1
Waagepetersen, H.S.2
-
22
-
-
0034307759
-
Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
-
Ward MW, Rego AC, Frenguelli BG. Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci. 2000;20:7208-19.
-
(2000)
J Neurosci
, vol.20
, pp. 7208-7219
-
-
Ward, M.W.1
Rego, A.C.2
Frenguelli, B.G.3
-
23
-
-
0033199019
-
Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurons
-
Vergun O, Keelan J, Khodorov BI. Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurons. J Physiol. 1999;519:451-66.
-
(1999)
J Physiol
, vol.519
, pp. 451-466
-
-
Vergun, O.1
Keelan, J.2
Khodorov, B.I.3
-
24
-
-
0038147047
-
Mitochondrial ATPsensitive potassium channel: A novel site for neuroprotection
-
Yamauchi T, Kashii S, Yasuyoshi H. Mitochondrial ATPsensitive potassium channel: a novel site for neuroprotection. Invest Ophthalmol Vis Sci. 2003;44:2750-6.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2750-2756
-
-
Yamauchi, T.1
Kashii, S.2
Yasuyoshi, H.3
-
25
-
-
50549096439
-
2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDS
-
2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDS. PLoS One. 2008;3:e2718.
-
(2008)
PLoS One
, vol.3
-
-
Sanz-Blasco, S.1
Valero, R.A.2
Nunez, L.3
|