Changes in intranuclear mobility of mature snrnps provide a mechanism for splicing defects in spinal muscular atrophy

Journal of Cell Science

Volumn 125, Issue 11, 2012, Pages 2626-2637

  Clelland, Allyson Kara ^a   Bales, Alexandra Beatrice E ^a   Sleeman, Judith Elizabeth ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Nuclear dynamics; Snrnps; Spinal muscular atrophy; Splicing speckles

Indexed keywords

MESSENGER RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN; SURVIVAL MOTOR NEURON PROTEIN;

ARTICLE; CELL MOTILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RNA SPLICING; SPINAL MUSCULAR ATROPHY; SPLICEOSOME;

CELL NUCLEUS; FATTY ACIDS, UNSATURATED; FIBROBLASTS; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; MUSCULAR ATROPHY, SPINAL; PROTEIN TRANSPORT; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA INTERFERENCE; RNA SPLICING; RNA, SMALL INTERFERING; SPLICEOSOMES; SURVIVAL OF MOTOR NEURON 1 PROTEIN;

EID: 84865046210     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.096867     Document Type: Article

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