The synthetic purine reversine selectively induces cell death of cancer cells

Journal of Cellular Biochemistry

Volumn 113, Issue 10, 2012, Pages 3207-3217

  Piccoli, Marco ^a,b   Palazzolo, Giacomo ^a,b   Conforti, Erika ^a,b   Lamorte, Giuseppe ^c   Papini, Nadia ^a,b   Creo, Pasquale ^b   Fania, Chiara ^a   Scaringi, Raffaella ^a,b   Bergante, Sonia ^a,b   Tringali, Cristina ^a,b   Roncoroni, Leda ^a,d   Mazzoleni, Stefania ^e   Doneda, Luisa ^a   Galli, Rossella ^e   Venerando, Bruno ^a,b   Tettamanti, Guido ^b   Gelfi, Cecilia ^a   Anastasia, Luigi ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS POLICLINICO SAN DONATO   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^e SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

cell reprogramming; new anti cancer drugs; Reversine; small molecules and stem cells

Indexed keywords

CELL CYCLE PROTEIN; PROTEIN P53; PURINE DERIVATIVE; REVERSINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE CHECKPOINT; CELL DIVISION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; SKIN FIBROBLAST;

ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; BLOTTING, WESTERN; CASPASES; CELL CYCLE CHECKPOINTS; CELL DEATH; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; ENDOREDUPLICATION; ENZYME ACTIVATION; FIBROBLASTS; FIBROSARCOMA; FLOW CYTOMETRY; GENE SILENCING; HELA CELLS; HUMANS; MORPHOLINES; PURINES; RNA, SMALL INTERFERING; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865019004     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24197     Document Type: Article

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