Synthesis and biological evaluation of myoseverin derivatives: Microtubule assembly inhibitors

Journal of Medicinal Chemistry

Volumn 44, Issue 26, 2001, Pages 4497-4500

  Chang, Y T ^a,b   Wignall, S M ^c   Rosania, G R ^b   Gray, N S ^d   Hanson, S R ^c   Su, A I ^b   Merlie, Jr ^c   Moon, H S ^a   Sangankar, S B ^a   Perez, O ^c   Heald, R ^c   Schultz, P G ^b,d  

^a NEW YORK UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DIMETHYL SULFOXIDE; DNA; MAYTANSINE; MYOSEVERIN B; MYOSEVERIN DERIVATIVE; PACLITAXEL; PURINE DERIVATIVE; RHIZOXIN; TUBULIN; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL GROWTH; CELL STRAIN U937; CONTROLLED STUDY; DNA CONTENT; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; NONHUMAN; STRUCTURE ACTIVITY RELATION; XENOPUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOPOLYMERS; CELL DIVISION; DEPRESSION, CHEMICAL; FLOW CYTOMETRY; HUMANS; MITOTIC SPINDLE APPARATUS; OOCYTES; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE EXTRACTS; TUBULIN; U937 CELLS; XENOPUS LAEVIS;

EID: 0035924176     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010451+     Document Type: Article

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