The role of glutamate signaling in pain processes and its regulation by GCP II inhibition

Current Medicinal Chemistry

Volumn 19, Issue 9, 2012, Pages 1323-1334

  Wozniak, K M ^a   Rojas, C ^a   Wu, Y ^a   Slusher, B S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Central nervous system; dorsal horn; Glutamate Carboxypeptidase II (GCPII); glutamate receptors; NAAG; neuropathy; pain; peripheral nervous system

Indexed keywords

2 [5 (4 DIMETHYLSULFAMOYLPHENYL) 6,7,8,9 TETRAHYDRO 8 METHYL 2 OXO 1H PYRROLO[3,2 H]ISOQUINOLIN 3 YLIMINOXY] 4 HYDROXYBUTYRIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; AV 101; AVP 923; AZD 2516; CNS 5161; DEXTROMETHORPHAN PLUS QUINIDINE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; KAINIC ACID RECEPTOR; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPEPTIDE; NGX 426; PERAMPENEL; RADIPRODIL; TEZAMPANEL; UNCLASSIFIED DRUG;

DIABETIC NEUROPATHY; ENZYME ACTIVITY; HUMAN; MIGRAINE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN; REVIEW;

ANALGESICS; ANIMALS; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMIC ACID; HUMANS; NOCICEPTION; PAIN; RECEPTORS, GLUTAMATE; SIGNAL TRANSDUCTION;

EID: 84863297131     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712799462630     Document Type: Review

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