NAAG peptidase inhibitors and their potential for diagnosis and therapy

Nature Reviews Drug Discovery

Volumn 4, Issue 12, 2005, Pages 1015-1026

  Zhou, Jia ^a   Neale, Joseph H ^b   Pomper, Martin G ^c   Kozikowski, Alan P ^a,d  

^a Acenta Discovery Incorporated   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 MERCAPTOPROPYL)PENTANEDIOIC ACID; 2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; 2 [3 (1,3 DICARBOXYPROPYL)UREIDO]PENTANEDIOIC ACID; 2 [3 (1,CARBOXY 3 METHYLBUTYL)UREIDO]PENTANEDIOIC ACID; 2 [3 [1,CARBOXY 3 (1H TETRAZOL 5 YL)PROPYL]UREIDO]PENTANEDIOIC ACID; 2 [3 [1,CARBOXY 3 (METHYLSULPHANYL)PROPYL]UREIDO]PENTANEDIOIC ACID; 2 [[BENZYLOXY(HYDROXYL)PHOSPHORYL]METHYL]PENTANEDIOIC ACID; 2 [HYDROXYPENTAFLUOROPHENYL(METHYL)PHOSPHINOYL(METHYL)]PENTANEDIOIC ACID; 2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 3 (2 MERCAPTOETHYL) 1H INDOLE 2 CARBOXYLIC ACID DERIVATIVE; 4,4' PHOSPHINICOBIS(BUTANE 1,3 DICARBOXYLIC ACID); DIPEPTIDE DERIVATIVE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GP 15000; GP 15232; GP 15693; HYDROXAMIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHENCYCLIDINE; PHENYLALKYLPHOSPHONAMIDIC ACID DERIVATIVE; PROSTATE SPECIFIC MEMBRANE ANTIGEN; QUISQUALIC ACID; TENOFOVIR; UNCLASSIFIED DRUG; VA 033; ZJ 11; ZJ 17; ZJ 38; ZJ 43; DIAGNOSTIC AGENT; PROTEINASE INHIBITOR;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANALGESIA; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CRYSTAL STRUCTURE; DIABETIC NEUROPATHY; DISEASE MODEL; DRUG DEPENDENCE; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SPECIFICITY; DRUG TOLERANCE; HUMAN; HUNTINGTON CHOREA; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIA; NEUROPATHIC PAIN; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PARKINSON DISEASE; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN STRUCTURE; REVIEW; SCHIZOPHRENIA; STRUCTURE ACTIVITY RELATION; TRAUMATIC BRAIN INJURY; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; MALE; NEUROLOGIC DISEASE; PROSTATE TUMOR;

ANIMALS; GLUTAMATE CARBOXYPEPTIDASE II; HUMANS; MALE; NERVOUS SYSTEM DISEASES; PROSTATIC NEOPLASMS; PROTEASE INHIBITORS;

EID: 33644700192     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd1903     Document Type: Review

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