Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function: I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residue

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 19301-19308

  Hiol, Abel ^a   Davey, Penelope C ^a   Osterhout, James L ^b   Waheed, Abdul A ^a   Fischer, Elizabeth R ^c   Chen, Ching Kang ^d   Milligan, Graeme ^e   Druey, Kirk M ^b   Jones, Teresa L Z ^a,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; ELECTRON MICROSCOPY; HYDROLYSIS; LIPIDS;

PLASMA MEMBRANES;

PROTEINS;

CYSTEINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; METHYL BETA CYCLODEXTRIN; PALMITIC ACID; PROTEIN RGS16; RGS PROTEIN; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG; BETA CYCLODEXTRIN DERIVATIVE; CAVEOLIN; CAVEOLIN 1; CYCLODEXTRIN; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE LIPID; METHYL-BETA-CYCLODEXTRIN; PROTEIN; RGS16 PROTEIN; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; LIPID MEMBRANE; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MEMBRANE; CELL STRAIN COS1; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENZYME ACTIVATION; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; LIVER; MALE; METABOLISM; MOUSE; MUTAGENESIS; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; ULTRASTRUCTURE;

ANIMALIA;

ANIMALS; BETA-CYCLODEXTRINS; CAVEOLIN 1; CAVEOLINS; CELL LINE; CELL MEMBRANE; COS CELLS; CYCLODEXTRINS; CYSTEINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; GLUTATHIONE TRANSFERASE; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE TRIPHOSPHATE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; IMMUNOBLOTTING; LIVER; MALE; MEMBRANE LIPIDS; MICE; MICROSCOPY, IMMUNOELECTRON; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS; PALMITIC ACID; PROTEINS; RATS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RECOMBINANT FUSION PROTEINS; RGS PROTEINS; SEROTONIN; TRANSFECTION;

EID: 0038143228     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210123200     Document Type: Article

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