Dual inhibitor of MurD and MurE ligases from escherichia coli and staphylococcus aureus

ACS Medicinal Chemistry Letters

Volumn 3, Issue 8, 2012, Pages 626-630

  Tomašić, Tihomir ^a   Šink, Roman ^a   Zidar, Nace ^a   Fic, Anja ^a   Contreras Martel, Carlos ^b   Dessen, Andréa ^b   Patin, Delphine ^c,d   Blanot, Didier ^c,d   Müller Premru, Manica ^a   Gobec, Stanislav ^a   Zega, Anamarija ^a   Kikelj, Danijel ^a   Mašič, Lucija Peterlin ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d CNRS   (France)

Author keywords

2 thioxothiazolidin 4 one; antibacterial agent; inhibitor; Mur ligase; peptidoglycan

Indexed keywords

ANTIINFECTIVE AGENT; DEXTRO GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLMURAMOYL LEVO ALANINE DEXTRO GLUTAMATE LIGASE; URIDINE DIPHOSPHATE N ACETYLMURAMOYL LEVO ALANINE DEXTRO GLUTAMATE MESO DIAMINOPIMELATE LIGASE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; DRUG DESIGN; DRUG SYNTHESIS; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IC 50; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 84864972354     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300047h     Document Type: Article

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