Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 1, 2009, Pages 153-157

  Tomašić, Tihomir ^a   Zidar, Nace ^a   Rupnik, Veronika ^a   Kovač, Andreja ^a   Blanot, Didier ^b   Gobec, Stanislav ^a   Kikelj, Danijel ^a   Mašič, Lucija Peterlin ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b IBBMC   (France)

Author keywords

Antibacterial agent; Glutamic acid; Inhibitor; MurD ligase

Indexed keywords

2,4 DIAMINOQUINAZOLINE DERIVATIVE; 5 BENZYLIDENE RHODANINE DERIVATIVE; ANTIINFECTIVE AGENT; BACTERIAL ENZYME; BENZYLIDENE DERIVATIVE; ENZYME INHIBITOR; GLUTAMIC ACID; LIGASE; PENTAPEPTIDE; PEPTIDOGLYCAN; PROTEIN MURD; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG TARGETING; ESCHERICHIA COLI; NONHUMAN; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BENZYLIDENE COMPOUNDS; ENZYME INHIBITORS; ESCHERICHIA COLI; GLUTAMIC ACID; INHIBITORY CONCENTRATION 50; PEPTIDE SYNTHASES; QUINAZOLINES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 57749085472     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.129     Document Type: Article

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