-
1
-
-
0022401034
-
Specificity of the uridine-diphosphate-N-acetylmuramyl-l-alanyl-d- glutamate: Meso-2,6-diaminopimelate synthetase from Escherichia coli
-
Abo-Ghalia M, Michaud C, Blanot D van Heijenoort J (1985) Specificity of the uridine-diphosphate-N-acetylmuramyl-l-alanyl-d-glutamate: meso-2,6-diaminopimelate synthetase from Escherichia coli. Eur J Biochem 153 : 81 87.
-
(1985)
Eur J Biochem
, vol.153
, pp. 81-87
-
-
Abo-Ghalia, M.1
Michaud, C.2
Blanot, D.3
Van Heijenoort, J.4
-
3
-
-
26444596157
-
Stereochemistry of reactions of the inhibitor/substrates l- and d-β-chloroalanine with β-mercaptoethanol catalysed by l-aspartate aminotransferase and d-amino acid aminotransferase respectively
-
Adams B, Lowpetch K, Thorndycroft F, Whyte SM Young DW (2005) Stereochemistry of reactions of the inhibitor/substrates l- and d-β-chloroalanine with β-mercaptoethanol catalysed by l-aspartate aminotransferase and d-amino acid aminotransferase respectively. Org Biomol Chem 3 : 3357 3364.
-
(2005)
Org Biomol Chem
, vol.3
, pp. 3357-3364
-
-
Adams, B.1
Lowpetch, K.2
Thorndycroft, F.3
Whyte, S.M.4
Young, D.W.5
-
4
-
-
0026589363
-
D-alanine : dd-alanine ligase of Escherichia coli. Expression, purification and inhibitory studies on the cloned enzyme
-
Al-Bar OAM, O'Connor CD, Giles IG Akhtar M (1992) d-alanine : d-alanine ligase of Escherichia coli. Expression, purification and inhibitory studies on the cloned enzyme. Biochem J 282 : 747 752.
-
(1992)
Biochem J
, vol.282
, pp. 747-752
-
-
Al-Bar, O.A.M.1
O'Connor, C.D.2
Giles, I.G.3
Akhtar, M.4
-
5
-
-
0017853042
-
Phosphonopeptides, a new class of synthetic antibacterial agents
-
Allen JG, Atherton FR, Hall MJ, Hassall CH, Holmes SW, Lambert RW, Nisbet LJ Ringrose PS (1978) Phosphonopeptides, a new class of synthetic antibacterial agents. Nature 272 : 56 58.
-
(1978)
Nature
, vol.272
, pp. 56-58
-
-
Allen, J.G.1
Atherton, F.R.2
Hall, M.J.3
Hassall, C.H.4
Holmes, S.W.5
Lambert, R.W.6
Nisbet, L.J.7
Ringrose, P.S.8
-
6
-
-
0030471790
-
Kinetic mechanism of the Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme: Use of a glutathione S-transferase fusion
-
Anderson MS, Eveland SS, Onishi HR Pompliano DL (1996) Kinetic mechanism of the Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme: use of a glutathione S-transferase fusion. Biochemistry 35 : 16264 16269.
-
(1996)
Biochemistry
, vol.35
, pp. 16264-16269
-
-
Anderson, M.S.1
Eveland, S.S.2
Onishi, H.R.3
Pompliano, D.L.4
-
9
-
-
0022547921
-
UDP-N-acetylmuramoyl-l-alanyl-d-glutamyl-l-lysine synthetase from Bacillus sphaericus: Activation by potassium phosphate
-
Anwar RA Vlaovic M (1986) UDP-N-acetylmuramoyl-l-alanyl-d-glutamyl-l- lysine synthetase from Bacillus sphaericus: activation by potassium phosphate. Biochem Cell Biol 64 : 297 303.
-
(1986)
Biochem Cell Biol
, vol.64
, pp. 297-303
-
-
Anwar, R.A.1
Vlaovic, M.2
-
10
-
-
0036323007
-
Biochemistry and molecular genetics of poly-γ-glutamate synthesis
-
Ashiuchi M Misono H (2002) Biochemistry and molecular genetics of poly-γ-glutamate synthesis. Appl Microbiol Biotechnol 59 : 9 14.
-
(2002)
Appl Microbiol Biotechnol
, vol.59
, pp. 9-14
-
-
Ashiuchi, M.1
Misono, H.2
-
11
-
-
0002679348
-
Inactivation of glutamate racemase of Pediococcus pentosaceus by l-serine-O-sulfate
-
Ashiuchi M, Yoshimura T, Esaki N, Ueno H Soda K (1993) Inactivation of glutamate racemase of Pediococcus pentosaceus by l-serine-O-sulfate. Biosci Biotechnol Biochem 57 : 1978 1979.
-
(1993)
Biosci Biotechnol Biochem
, vol.57
, pp. 1978-1979
-
-
Ashiuchi, M.1
Yoshimura, T.2
Esaki, N.3
Ueno, H.4
Soda, K.5
-
12
-
-
0031778765
-
Properties of glutamate racemase from Bacillus subtilis IFO 3336 producing poly-γ-glutamate
-
Ashiuchi M, Tani K, Soda K Misono H (1998) Properties of glutamate racemase from Bacillus subtilis IFO 3336 producing poly-γ-glutamate. J Biochem (Tokyo) 123 : 1156 1163.
-
(1998)
J Biochem (Tokyo)
, vol.123
, pp. 1156-1163
-
-
Ashiuchi, M.1
Tani, K.2
Soda, K.3
Misono, H.4
-
13
-
-
0033125690
-
Characterization of yrpC gene product of Bacillus subtilis IFO 3336 as glutamate racemase isozyme
-
Ashiuchi M, Soda K Misono H (1999) Characterization of yrpC gene product of Bacillus subtilis IFO 3336 as glutamate racemase isozyme. Biosci Biotechnol Biochem 63 : 792 798.
-
(1999)
Biosci Biotechnol Biochem
, vol.63
, pp. 792-798
-
-
Ashiuchi, M.1
Soda, K.2
Misono, H.3
-
14
-
-
0037131231
-
Glutamate racemase is an endogenous DNA gyrase inhibitor
-
Ashiuchi M, Kuwana E, Yamamoto T, Komatsu K, Soda K Misono H (2002) Glutamate racemase is an endogenous DNA gyrase inhibitor. J Biol Chem 277 : 39070 39073.
-
(2002)
J Biol Chem
, vol.277
, pp. 39070-39073
-
-
Ashiuchi, M.1
Kuwana, E.2
Yamamoto, T.3
Komatsu, K.4
Soda, K.5
Misono, H.6
-
15
-
-
0038434051
-
Differences in effects on DNA gyrase activity between two glutamate racemases of Bacillus subtilis, the poly-γ-glutamate synthesis-linking Glr enzyme and the YrpC (MurI) isozyme
-
Ashiuchi M, Kuwana E, Komatsu K, Soda K Misono H (2003) Differences in effects on DNA gyrase activity between two glutamate racemases of Bacillus subtilis, the poly-γ-glutamate synthesis-linking Glr enzyme and the YrpC (MurI) isozyme. FEMS Microbiol Lett 223 : 221 225.
-
(2003)
FEMS Microbiol Lett
, vol.223
, pp. 221-225
-
-
Ashiuchi, M.1
Kuwana, E.2
Komatsu, K.3
Soda, K.4
Misono, H.5
-
16
-
-
34548409520
-
Genetic design of conditional d-glutamate auxotrophy for Bacillus subtilis: Use of a vector-borne poly-γ-glutamate synthetic system
-
Ashiuchi M, Nishikawa Y, Matsunaga K, Yamamoto M, Shimanouchi K Misono H (2007) Genetic design of conditional d-glutamate auxotrophy for Bacillus subtilis: use of a vector-borne poly-γ-glutamate synthetic system. Biochem Biophys Res Commun 362 : 646 650.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 646-650
-
-
Ashiuchi, M.1
Nishikawa, Y.2
Matsunaga, K.3
Yamamoto, M.4
Shimanouchi, K.5
Misono, H.6
-
17
-
-
0018745481
-
Phosphonopeptides as antibacterial agents: Rationale, chemistry, and structure-activity relationships
-
Atherton FR, Hall MJ, Hassall CH, Lambert RW Ringrose PS (1979a) Phosphonopeptides as antibacterial agents: rationale, chemistry, and structure-activity relationships. Antimicrob Agents Chemother 15 : 677 683.
-
(1979)
Antimicrob Agents Chemother
, vol.15
, pp. 677-683
-
-
Atherton, F.R.1
Hall, M.J.2
Hassall, C.H.3
Lambert, R.W.4
Ringrose, P.S.5
-
18
-
-
0018774396
-
Phosphonopeptides as antibacterial agents: Mechanism of action of alaphosphin
-
Atherton FR, Hall MJ, Hassall CH, Lambert RW, Lloyd WJ Ringrose PS (1979b) Phosphonopeptides as antibacterial agents: mechanism of action of alaphosphin. Antimicrob Agents Chemother 15 : 696 705.
-
(1979)
Antimicrob Agents Chemother
, vol.15
, pp. 696-705
-
-
Atherton, F.R.1
Hall, M.J.2
Hassall, C.H.3
Lambert, R.W.4
Lloyd, W.J.5
Ringrose, P.S.6
-
19
-
-
0020400143
-
Antibacterial activity and mechanism of action of phosphonopeptides based on aminomethylphosphonic acid
-
Atherton FR, Hall MJ, Hassall CH, Lambert RW, Lloyd WJ, Ringrose PS Westmacott D (1982) Antibacterial activity and mechanism of action of phosphonopeptides based on aminomethylphosphonic acid. Antimicrob Agents Chemother 22 : 571 578.
-
(1982)
Antimicrob Agents Chemother
, vol.22
, pp. 571-578
-
-
Atherton, F.R.1
Hall, M.J.2
Hassall, C.H.3
Lambert, R.W.4
Lloyd, W.J.5
Ringrose, P.S.6
Westmacott, D.7
-
20
-
-
13344278558
-
Synthesis of N-acetylmuramic acid derivatives as potential inhibitors of the d-glutamic acid-adding enzyme
-
Auger G, van Heijenoort J, Blanot D Deprun C (1995) Synthesis of N-acetylmuramic acid derivatives as potential inhibitors of the d-glutamic acid-adding enzyme. J Prakt Chem 337 : 351 357.
-
(1995)
J Prakt Chem
, vol.337
, pp. 351-357
-
-
Auger, G.1
Van Heijenoort, J.2
Blanot, D.3
Deprun, C.4
-
21
-
-
0030570736
-
Effect of analogues of diaminopimelic acid on the meso-diaminopimelate- adding enzyme from Escherichia coli
-
Auger G, van Heijenoort J, Vederas JC Blanot D (1996) Effect of analogues of diaminopimelic acid on the meso-diaminopimelate-adding enzyme from Escherichia coli. FEBS Lett 391 : 171 174.
-
(1996)
FEBS Lett
, vol.391
, pp. 171-174
-
-
Auger, G.1
Van Heijenoort, J.2
Vederas, J.C.3
Blanot, D.4
-
22
-
-
0032103759
-
Large-scale preparation, purification, and crystallization of UDP-N-acetylmuramoyl-l-alanine: D-glutamate ligase from Escherichia coli
-
Auger G, Martin L, Bertrand J, Ferrari P, Fanchon E, Vaganay S, Pétillot Y, van Heijenoort J, Blanot D Dideberg O (1998) Large-scale preparation, purification, and crystallization of UDP-N-acetylmuramoyl-l- alanine: d-glutamate ligase from Escherichia coli. Protein Expr Purif 13 : 23 29.
-
(1998)
Protein Expr Purif
, vol.13
, pp. 23-29
-
-
Auger, G.1
Martin, L.2
Bertrand, J.3
Ferrari, P.4
Fanchon, E.5
Vaganay, S.6
Pétillot, Y.7
Van Heijenoort, J.8
Blanot, D.9
Dideberg, O.10
-
23
-
-
37049090727
-
Stereochemistry of conversion of the suicide substrates β-chloro-d-alanine and d- and l-serine O-sulfates into pyruvate by d-amino acid aminotransferase and by l-aspartate aminotransferase
-
Axelsson BS, Floss HG, Lee SG, Saeed A, Spencer PA Young DW (1994) Stereochemistry of conversion of the suicide substrates β-chloro-d-alanine and d- and l-serine O-sulfates into pyruvate by d-amino acid aminotransferase and by l-aspartate aminotransferase. J Chem Soc Perkin Trans 1 2137 2142.
-
(1994)
J Chem Soc Perkin Trans 1
, pp. 2137-2142
-
-
Axelsson, B.S.1
Floss, H.G.2
Lee, S.G.3
Saeed, A.4
Spencer, P.A.5
Young, D.W.6
-
24
-
-
0035715193
-
The cell wall and cell division gene cluster in the mra operon of Pseudomonas aeruginosa: Cloning, production, and purification of active enzymes
-
Azzolina BA, Yuan X, Anderson MS El-Sherbeini M (2001) The cell wall and cell division gene cluster in the mra operon of Pseudomonas aeruginosa: cloning, production, and purification of active enzymes. Protein Expr Purif 21 : 393 400.
-
(2001)
Protein Expr Purif
, vol.21
, pp. 393-400
-
-
Azzolina, B.A.1
Yuan, X.2
Anderson, M.S.3
El-Sherbeini, M.4
-
25
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL Mori H (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2 : 1 11.
-
(2006)
Mol Syst Biol
, vol.2
, pp. 1-11
-
-
Baba, T.1
Ara, T.2
Hasegawa, M.3
Takai, Y.4
Okumura, Y.5
Baba, M.6
Datsenko, K.A.7
Tomita, M.8
Wanner, B.L.9
Mori, H.10
-
26
-
-
34248670666
-
An improved total synthesis of UDP-N-acetyl-muramic acid
-
Babič A Pečar S (2007) An improved total synthesis of UDP-N-acetyl-muramic acid. Tetrahedron Lett 48 : 4403 4405.
-
(2007)
Tetrahedron Lett
, vol.48
, pp. 4403-4405
-
-
Babič, A.1
Pečar, S.2
-
27
-
-
39149116111
-
-
Chemoenzymatic synthesis of the nucleotide substrates of the Mur ligases. 5th Joint Meeting on Medicinal Chemistry, June 17-21, Portorož, Slovenia, (Kikelj D, ed.), pp. 1-4. Medimond Srl, Bologna, Italy.
-
Babič A, Patin D, Boniface A, Hervé M, Mengin-Lecreulx D, Pečar S, Gobec S Blanot D (2007) Chemoenzymatic synthesis of the nucleotide substrates of the Mur ligases. 5th Joint Meeting on Medicinal Chemistry, June 17-21, Portorož, Slovenia, (Kikelj D, ed.), pp. 1-4. Medimond Srl, Bologna, Italy.
-
(2007)
-
-
Babič, A.1
Patin, D.2
Boniface, A.3
Hervé, M.4
Mengin-Lecreulx, D.5
Pečar, S.6
Gobec, S.7
Blanot, D.8
-
28
-
-
33748764203
-
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA
-
Bachelier A, Mayer R Klein CD (2006) Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA. Bioorg Med Chem Lett 16 : 5605 5609.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 5605-5609
-
-
Bachelier, A.1
Mayer, R.2
Klein, C.D.3
-
29
-
-
0021928231
-
Purification of an alanine racemase from Streptococcus faecalis and analysis of its inactivation by (1-aminoethyl)phosphonic acid enantiomers
-
Badet B Walsh C (1985) Purification of an alanine racemase from Streptococcus faecalis and analysis of its inactivation by (1-aminoethyl) phosphonic acid enantiomers. Biochemistry 24 : 1333 1341.
-
(1985)
Biochemistry
, vol.24
, pp. 1333-1341
-
-
Badet, B.1
Walsh, C.2
-
30
-
-
0021769535
-
Inactivation of the dadB Salmonella typhimurium alanine racemase by D and L isomers of β-substituted alanines: Kinetics, stoichiometry, active site peptide sequencing, and reaction mechanism
-
Badet B, Roise D Walsh CT (1984) Inactivation of the dadB Salmonella typhimurium alanine racemase by D and L isomers of β-substituted alanines: kinetics, stoichiometry, active site peptide sequencing, and reaction mechanism. Biochemistry 23 : 5188 5194.
-
(1984)
Biochemistry
, vol.23
, pp. 5188-5194
-
-
Badet, B.1
Roise, D.2
Walsh, C.T.3
-
31
-
-
0022452428
-
Time-dependent inhibition of Bacillus stearothermophilus alanine racemase by (1-aminoethyl)phosphonate isomers by isomerization to noncovalent slowly dissociating enzyme-(1-aminoethyl)phosphonate complexes
-
Badet B, Inagaki K, Soda K Walsh CT (1986) Time-dependent inhibition of Bacillus stearothermophilus alanine racemase by (1-aminoethyl)phosphonate isomers by isomerization to noncovalent slowly dissociating enzyme-(1- aminoethyl)phosphonate complexes. Biochemistry 25 : 3275 3282.
-
(1986)
Biochemistry
, vol.25
, pp. 3275-3282
-
-
Badet, B.1
Inagaki, K.2
Soda, K.3
Walsh, C.T.4
-
32
-
-
0023280276
-
Glucosamine synthetase from Escherichia coli: Purification, properties, and glutamine-utilizing site location
-
Badet B, Vermoote P, Haumont PY, Lederer F Le Goffic F (1987) Glucosamine synthetase from Escherichia coli: purification, properties, and glutamine-utilizing site location. Biochemistry 26 : 1940 1948.
-
(1987)
Biochemistry
, vol.26
, pp. 1940-1948
-
-
Badet, B.1
Vermoote, P.2
Haumont, P.Y.3
Lederer, F.4
Le Goffic, F.5
-
34
-
-
0001083651
-
Mechanistic investigations on glucosamine-6-phosphate synthase
-
Badet-Denisot MA, René L Badet B (1993) Mechanistic investigations on glucosamine-6-phosphate synthase. Bull Soc Chim Fr 130 : 249 255.
-
(1993)
Bull Soc Chim Fr
, vol.130
, pp. 249-255
-
-
Badet-Denisot, M.A.1
René, L.2
Badet, B.3
-
35
-
-
0028948403
-
Nitrogen transfer in E. coli glucosamine-6-phosphate synthase investigations using substrate and bisubstrate analogs
-
Badet-Denisot MA, Leriche C, Massière F Badet B (1995) Nitrogen transfer in E. coli glucosamine-6-phosphate synthase investigations using substrate and bisubstrate analogs. Bioorg Med Chem Lett 5 : 815 820.
-
(1995)
Bioorg Med Chem Lett
, vol.5
, pp. 815-820
-
-
Badet-Denisot, M.A.1
Leriche, C.2
Massière, F.3
Badet, B.4
-
36
-
-
0031003988
-
Characterization of l-glutamine: D-fructose-6-phosphate amidotransferase from an extreme thermophile Thermus thermophilus HB8
-
Badet-Denisot MA, Fernandez-Herrero LA, Berenguer J, Ooi T Badet B (1997) Characterization of l-glutamine: d-fructose-6-phosphate amidotransferase from an extreme thermophile Thermus thermophilus HB8. Arch Biochem Biophys 337 : 129 136.
-
(1997)
Arch Biochem Biophys
, vol.337
, pp. 129-136
-
-
Badet-Denisot, M.A.1
Fernandez-Herrero, L.A.2
Berenguer, J.3
Ooi, T.4
Badet, B.5
-
37
-
-
0036203528
-
Development of a whole-cell assay for peptidoglycan biosynthesis inhibitors
-
Barbosa MDFS, Yang G, Fang J, Kurilla MG Pompliano DL (2002) Development of a whole-cell assay for peptidoglycan biosynthesis inhibitors. Antimicrob Agents Chemother 46 : 943 946.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 943-946
-
-
Mdfs, B.1
Yang, G.2
Fang, J.3
Kurilla, M.G.4
Pompliano, D.L.5
-
38
-
-
0034770091
-
Identification and characterization of new inhibitors of the Escherichia coli MurA enzyme
-
Baum EZ, Montenegro DA, Licata L, Turchi I, Webb GC, Foleno BD Bush K (2001) Identification and characterization of new inhibitors of the Escherichia coli MurA enzyme. Antimicrob Agents Chemother 45 : 3182 3188.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 3182-3188
-
-
Baum, E.Z.1
Montenegro, D.A.2
Licata, L.3
Turchi, I.4
Webb, G.C.5
Foleno, B.D.6
Bush, K.7
-
39
-
-
29944442521
-
Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF
-
Baum EZ, Crespo-Carbone SM, Abbanat D, Foleno B, Maden A, Goldschmidt R Bush K (2006) Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF. Antimicrob Agents Chemother 50 : 230 236.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 230-236
-
-
Baum, E.Z.1
Crespo-Carbone, S.M.2
Abbanat, D.3
Foleno, B.4
Maden, A.5
Goldschmidt, R.6
Bush, K.7
-
40
-
-
0030041610
-
Active site-directed inactivation of Escherichia coli glucosamine-6-phosphate synthase. Determination of the fructose 6-phosphate binding constant using a carbohydrate-based inactivator
-
Bearne SL (1996) Active site-directed inactivation of Escherichia coli glucosamine-6-phosphate synthase. Determination of the fructose 6-phosphate binding constant using a carbohydrate-based inactivator. J Biol Chem 271 : 3052 3057.
-
(1996)
J Biol Chem
, vol.271
, pp. 3052-3057
-
-
Bearne, S.L.1
-
41
-
-
0034614411
-
Inhibition of Escherichia coli glucosamine-6-phosphate synthase by reactive intermediate analogues. the role of the 2-amino function in catalysis
-
Bearne SL Blouin C (2000) Inhibition of Escherichia coli glucosamine-6-phosphate synthase by reactive intermediate analogues. The role of the 2-amino function in catalysis. J Biol Chem 275 : 135 140.
-
(2000)
J Biol Chem
, vol.275
, pp. 135-140
-
-
Bearne, S.L.1
Blouin, C.2
-
42
-
-
0027512265
-
Overexpression, purification, and mechanistic study of UDP-N-acetylenolpyruvylglucosamine reductase
-
Benson TE, Marquardt JL, Marquardt AC, Etzkorn FA Walsh CT (1993) Overexpression, purification, and mechanistic study of UDP-N- acetylenolpyruvylglucosamine reductase. Biochemistry 32 : 2024 2030.
-
(1993)
Biochemistry
, vol.32
, pp. 2024-2030
-
-
Benson, T.E.1
Marquardt, J.L.2
Marquardt, A.C.3
Etzkorn, F.A.4
Walsh, C.T.5
-
43
-
-
0029056202
-
An enzyme-substrate complex involved in bacterial cell wall biosynthesis
-
Benson TE, Filman DJ, Walsh CT Hogle JM (1995) An enzyme-substrate complex involved in bacterial cell wall biosynthesis. Nat Struct Biol 2 : 644 653.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 644-653
-
-
Benson, T.E.1
Filman, D.J.2
Walsh, C.T.3
Hogle, J.M.4
-
44
-
-
0029643799
-
The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls
-
Benson TE, Walsh CT Hogle JM (1996) The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls. Structure 4 : 47 54.
-
(1996)
Structure
, vol.4
, pp. 47-54
-
-
Benson, T.E.1
Walsh, C.T.2
Hogle, J.M.3
-
45
-
-
0031054015
-
X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-Å resolution
-
Benson TE, Walsh CT Hogle JM (1997a) X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-Å resolution. Biochemistry 36 : 806 811.
-
(1997)
Biochemistry
, vol.36
, pp. 806-811
-
-
Benson, T.E.1
Walsh, C.T.2
Hogle, J.M.3
-
46
-
-
0031047397
-
Kinetic characterization of wild-type and S229A mutant of MurB: Evidence for the role of Ser 229 as a general catalyst
-
Benson TE, Walsh CT Massey V (1997b) Kinetic characterization of wild-type and S229A mutant of MurB: evidence for the role of Ser 229 as a general catalyst. Biochemistry 36 : 796 805.
-
(1997)
Biochemistry
, vol.36
, pp. 796-805
-
-
Benson, T.E.1
Walsh, C.T.2
Massey, V.3
-
47
-
-
0035957048
-
A structural variation for MurB: X-ray crystal structure of Staphylococcus aureus UDP-N-acetylenolpyruvylglucosamine reductase (MurB)
-
Benson TE, Harris MS, Choi GH, Cialdella JI, Herberg JT, Martin JP Jr. Baldwin ET (2001) A structural variation for MurB: X-ray crystal structure of Staphylococcus aureus UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Biochemistry 40 : 2340 2350.
-
(2001)
Biochemistry
, vol.40
, pp. 2340-2350
-
-
Benson, T.E.1
Harris, M.S.2
Choi, G.H.3
Cialdella, J.I.4
Herberg, J.T.5
Martin Jr., J.P.6
Baldwin, E.T.7
-
48
-
-
0037384217
-
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis
-
Berger BJ, English S, Chan G Knodel MH (2003) Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis. J Bacteriol 185 : 2418 2431.
-
(2003)
J Bacteriol
, vol.185
, pp. 2418-2431
-
-
Berger, B.J.1
English, S.2
Chan, G.3
Knodel, M.H.4
-
49
-
-
0002739485
-
Linkage map of Escherichia coli K-12, edition 9
-
Neidhardt, F.C., Curtiss, R.III., Ingraham, J.L., Lin, E.C.C., Low, K.B., Magasanik, B., Reznikoff, W.S., Riley, M., Schaechter, M. Umbarger, H.E., eds), pp. ASM Press, Washington, DC.
-
Berlyn KB, Low KB Rudd KE (1996) Linkage map of Escherichia coli K-12, edition 9. Escherichia coli and Salmonella: Cellular and Molecular Biology, Vol. 2 (Neidhardt FC, Curtiss R III., Ingraham JL, Lin ECC, Low KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M Umbarger HE, eds), pp. 1715 1902. ASM Press, Washington, DC.
-
(1996)
Escherichia Coli and Salmonella: Cellular and Molecular Biology
, vol.2
, pp. 1715-1902
-
-
Berlyn, K.B.1
Low, K.B.2
Rudd, K.E.3
-
50
-
-
0030927105
-
Crystal structure of UDP-N-acetylmuramoyl-l-alanine: D-glutamate ligase from Escherichia coli
-
Bertrand JA, Auger G, Fanchon E, Martin L, Blanot D, van Heijenoort J Dideberg O (1997) Crystal structure of UDP-N-acetylmuramoyl-l-alanine: d-glutamate ligase from Escherichia coli. EMBO J 16 : 3416 3425.
-
(1997)
EMBO J
, vol.16
, pp. 3416-3425
-
-
Bertrand, J.A.1
Auger, G.2
Fanchon, E.3
Martin, L.4
Blanot, D.5
Van Heijenoort, J.6
Dideberg, O.7
-
51
-
-
0033546272
-
Determination of the MurD mechanism through crystallographic analysis of enzymes complexes
-
Bertrand JA, Auger G, Martin L, Fanchon E, Blanot D, Le Beller D, van Heijenoort J Dideberg O (1999) Determination of the MurD mechanism through crystallographic analysis of enzymes complexes. J Mol Biol 289 : 579 590.
-
(1999)
J Mol Biol
, vol.289
, pp. 579-590
-
-
Bertrand, J.A.1
Auger, G.2
Martin, L.3
Fanchon, E.4
Blanot, D.5
Le Beller, D.6
Van Heijenoort, J.7
Dideberg, O.8
-
52
-
-
0034283162
-
'Open' structures of MurD: Domain movements and structural similarities with folylpolyglutamate synthetase
-
Bertrand JA, Fanchon E, Martin L, Chantalat L, Auger G, Blanot D, van Heijenoort J Dideberg O (2001) 'Open' structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase. J Mol Biol 301 : 1257 1266.
-
(2001)
J Mol Biol
, vol.301
, pp. 1257-1266
-
-
Bertrand, J.A.1
Fanchon, E.2
Martin, L.3
Chantalat, L.4
Auger, G.5
Blanot, D.6
Van Heijenoort, J.7
Dideberg, O.8
-
53
-
-
26844437323
-
A de novo designed inhibitor of d-Ala-d-Ala ligase from E. coli
-
Besong GE, Bostock JM, Stubbings W, Chopra I, Roper DI, Lloyd AJ, Fishwick CW Johnson AP (2005) A de novo designed inhibitor of d-Ala-d-Ala ligase from E. coli. Angew Chem Int Ed Engl 44 : 6403 6406.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 6403-6406
-
-
Besong, G.E.1
Bostock, J.M.2
Stubbings, W.3
Chopra, I.4
Roper, D.I.5
Lloyd, A.J.6
Fishwick, C.W.7
Johnson, A.P.8
-
55
-
-
4644288274
-
Expression, purification, crystallization and preliminary characterization of uridine 5′-diphospho-N-acetylmuramoyl l-alanyl-d-glutamate: Lysine ligase (MurE) from Streptococcus pneumoniae 110K/70
-
Blewett AM, Lloyd AJ, Echalier A, Fülöp V, Dowson CG, Bugg TDH Roper DI (2004) Expression, purification, crystallization and preliminary characterization of uridine 5′-diphospho-N-acetylmuramoyl l-alanyl-d-glutamate: lysine ligase (MurE) from Streptococcus pneumoniae 110K/70. Acta Cryst D60 : 359 361.
-
(2004)
Acta Cryst
, vol.60
, pp. 359-361
-
-
Blewett, A.M.1
Lloyd, A.J.2
Echalier, A.3
Fülöp, V.4
Dowson, C.G.5
Bugg, T.D.H.6
Roper, D.I.7
-
56
-
-
0022978531
-
Mechanisms of action of chloroalanyl antibacterial peptides. Identification of the intracellular enzymes inactivated on treatment of Escherichia coli JSR-O with the dipeptide βcl-lAla-βCl-lAla
-
Boisvert W, Cheung KS, Lerner SA Johnston M (1986) Mechanisms of action of chloroalanyl antibacterial peptides. Identification of the intracellular enzymes inactivated on treatment of Escherichia coli JSR-O with the dipeptide βCl-lAla-βCl-lAla. J Biol Chem 261 : 7871 7878.
-
(1986)
J Biol Chem
, vol.261
, pp. 7871-7878
-
-
Boisvert, W.1
Cheung, K.S.2
Lerner, S.A.3
Johnston, M.4
-
57
-
-
39149087761
-
-
Etude des relations structure-activité au sein de la famille des Mur synthétases, enzymes de la voie de biosynthèse du peptidoglycane. Ph.D. Thesis, Université Paris-Sud, Orsay, France.
-
Boniface A (2007). Etude des relations structure-activité au sein de la famille des Mur synthétases, enzymes de la voie de biosynthèse du peptidoglycane. Ph.D. Thesis, Université Paris-Sud, Orsay, France.
-
(2007)
-
-
Boniface, A.1
-
58
-
-
33744937347
-
The MurE synthetase from Thermotoga maritima is endowed with an unusual d-lysine adding activity
-
Boniface A, Bouhss A, Mengin-Lecreulx D Blanot D (2006) The MurE synthetase from Thermotoga maritima is endowed with an unusual d-lysine adding activity. J Biol Chem 281 : 15680 15686.
-
(2006)
J Biol Chem
, vol.281
, pp. 15680-15686
-
-
Boniface, A.1
Bouhss, A.2
Mengin-Lecreulx, D.3
Blanot, D.4
-
59
-
-
0032831101
-
Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis
-
Born TL Blanchard JS (1999) Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis. Curr Opin Chem Biol 3 : 603 613.
-
(1999)
Curr Opin Chem Biol
, vol.3
, pp. 603-613
-
-
Born, T.L.1
Blanchard, J.S.2
-
60
-
-
0030880888
-
Invariant amino acids in the Mur peptide synthetases of bacterial peptidoglycan synthesis and their modification by site-directed mutagenesis in the UDP-MurNAc: L-alanine ligase from Escherichia coli
-
Bouhss A, Mengin-Lecreulx D, Blanot D, van Heijenoort J Parquet C (1997) Invariant amino acids in the Mur peptide synthetases of bacterial peptidoglycan synthesis and their modification by site-directed mutagenesis in the UDP-MurNAc: l-alanine ligase from Escherichia coli. Biochemistry 36 : 11556 11563.
-
(1997)
Biochemistry
, vol.36
, pp. 11556-11563
-
-
Bouhss, A.1
Mengin-Lecreulx, D.2
Blanot, D.3
Van Heijenoort, J.4
Parquet, C.5
-
61
-
-
0032768860
-
Formation of adenosine 5′-tetraphosphate from the acyl phosphate intermediate: A difference between the MurC and MurD synthetases of Escherichia coli
-
Bouhss A, Dementin S, van Heijenoort J, Parquet C Blanot D (1999a) Formation of adenosine 5′-tetraphosphate from the acyl phosphate intermediate: a difference between the MurC and MurD synthetases of Escherichia coli. FEBS Lett 453 : 15 19.
-
(1999)
FEBS Lett
, vol.453
, pp. 15-19
-
-
Bouhss, A.1
Dementin, S.2
Van Heijenoort, J.3
Parquet, C.4
Blanot, D.5
-
62
-
-
0033592452
-
Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-l-alanine: D-glutamate ligase (MurD)
-
Bouhss A, Dementin S, Parquet C, Mengin-Lecreulx D, Bertrand JA, Le Beller D, Dideberg O, van Heijenoort J Blanot D (1999b) Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-l-alanine: d-glutamate ligase (MurD). Biochemistry 38 : 12240 12247.
-
(1999)
Biochemistry
, vol.38
, pp. 12240-12247
-
-
Bouhss, A.1
Dementin, S.2
Parquet, C.3
Mengin-Lecreulx, D.4
Bertrand, J.A.5
Le Beller, D.6
Dideberg, O.7
Van Heijenoort, J.8
Blanot, D.9
-
63
-
-
0036403545
-
MurC and MurD synthetases of peptidoglycan biosynthesis: Borohydride trapping of acyl-phosphate intermediates
-
Bouhss A, Dementin S, van Heijenoort J, Parquet C Blanot D (2002) MurC and MurD synthetases of peptidoglycan biosynthesis: borohydride trapping of acyl-phosphate intermediates. Methods Enzymol 354 : 189 196.
-
(2002)
Methods Enzymol
, vol.354
, pp. 189-196
-
-
Bouhss, A.1
Dementin, S.2
Van Heijenoort, J.3
Parquet, C.4
Blanot, D.5
-
64
-
-
3142744588
-
Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis
-
Bouhss A, Crouvoisier M, Blanot D Mengin-Lecreulx D (2004) Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis. J Biol Chem 279 : 29974 29980.
-
(2004)
J Biol Chem
, vol.279
, pp. 29974-29980
-
-
Bouhss, A.1
Crouvoisier, M.2
Blanot, D.3
Mengin-Lecreulx, D.4
-
66
-
-
0037430432
-
Discovery of the first antibacterial small molecule inhibitors of MurB
-
Bronson JJ, DenBleyker KL, Falk PJ, Mate RA, Ho HT, Pucci MJ Snyder LB (2003) Discovery of the first antibacterial small molecule inhibitors of MurB. Bioorg Med Chem Lett 13 : 873 875.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 873-875
-
-
Bronson, J.J.1
Denbleyker, K.L.2
Falk, P.J.3
Mate, R.A.4
Ho, H.T.5
Pucci, M.J.6
Snyder, L.B.7
-
67
-
-
0037177870
-
Kinetic characterization of human glutamine-fructose-6-phosphate amidotransferase I. Potent feedback inhibition by glucosamine 6-phosphate
-
Broschat KO, Gorka C, Page JD, Martin-Berger CL, Davies MS, Huang H, Gulve EA, Salsgiver WJ Kasten TP (2002) Kinetic characterization of human glutamine-fructose-6-phosphate amidotransferase I. Potent feedback inhibition by glucosamine 6-phosphate. J Biol Chem 277 : 14764 14770.
-
(2002)
J Biol Chem
, vol.277
, pp. 14764-14770
-
-
Broschat, K.O.1
Gorka, C.2
Page, J.D.3
Martin-Berger, C.L.4
Davies, M.S.5
Huang, H.6
Gulve, E.A.7
Salsgiver, W.J.8
Kasten, T.P.9
-
68
-
-
0027930665
-
Detection and characterization of a phospholactoyl-enzyme adduct in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ
-
Brown ED, Marquardt JL, Lee JP, Walsh CT Anderson KS (1994) Detection and characterization of a phospholactoyl-enzyme adduct in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ. Biochemistry 33 : 10638 10645.
-
(1994)
Biochemistry
, vol.33
, pp. 10638-10645
-
-
Brown, E.D.1
Marquardt, J.L.2
Lee, J.P.3
Walsh, C.T.4
Anderson, K.S.5
-
69
-
-
0029064598
-
MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli
-
Brown ED, Vivas EI, Walsh CT Kolter R (1995) MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli. J Bacteriol 177 : 4194 4197.
-
(1995)
J Bacteriol
, vol.177
, pp. 4194-4197
-
-
Brown, E.D.1
Vivas, E.I.2
Walsh, C.T.3
Kolter, R.4
-
70
-
-
0033517131
-
Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: A paradigm for the related pyrophosphorylase superfamily
-
Brown K, Pompeo F, Dixon S, Mengin-Lecreulx D, Cambillau C Bourne Y (1999) Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily. EMBO J 18 : 4096 4107.
-
(1999)
EMBO J
, vol.18
, pp. 4096-4107
-
-
Brown, K.1
Pompeo, F.2
Dixon, S.3
Mengin-Lecreulx, D.4
Cambillau, C.5
Bourne, Y.6
-
71
-
-
0026880575
-
Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: Enzymology, antibiotics, and antibiotic resistance
-
Bugg TDH Walsh CT (1992) Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance. Nat Prod Rep 9 : 199 215.
-
(1992)
Nat Prod Rep
, vol.9
, pp. 199-215
-
-
Bugg, T.D.H.1
Walsh, C.T.2
-
72
-
-
0026355435
-
Molecular basis of vancomycin resistance in Enterococcus faecium BM4147: Biosynthesis of depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA
-
Bugg TDH, Wright GD, Dutka-Malen S, Arthur M, Courvalin P Walsh CT (1991) Molecular basis of vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry 30 : 10408 10415.
-
(1991)
Biochemistry
, vol.30
, pp. 10408-10415
-
-
Bugg, T.D.H.1
Wright, G.D.2
Dutka-Malen, S.3
Arthur, M.4
Courvalin, P.5
Walsh, C.T.6
-
73
-
-
33646462282
-
Antibiofilm activity of GlmU enzyme inhibitors against catheter-associated uropathogens
-
Burton E, Gawande PV, Yakandawala N, LoVetri K, Zhanel GG, Romeo T, Friesen AD Madhyastha S (2006) Antibiofilm activity of GlmU enzyme inhibitors against catheter-associated uropathogens. Antimicrob Agents Chemother 50 : 1835 1840.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1835-1840
-
-
Burton, E.1
Gawande, P.V.2
Yakandawala, N.3
Lovetri, K.4
Zhanel, G.G.5
Romeo, T.6
Friesen, A.D.7
Madhyastha, S.8
-
74
-
-
0141919817
-
Nonenzymatic breakdown of the tetrahedral (α-carboxyketal phosphate) intermediates of MurA and AroA, two carboxyvinyl transferases. Protonation of different functional groups controls the rate and fate of breakdown
-
Byczynski B, Mizyed S Berti PJ (2003) Nonenzymatic breakdown of the tetrahedral (α-carboxyketal phosphate) intermediates of MurA and AroA, two carboxyvinyl transferases. Protonation of different functional groups controls the rate and fate of breakdown. J Am Chem Soc 125 : 12541 12550.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 12541-12550
-
-
Byczynski, B.1
Mizyed, S.2
Berti, P.J.3
-
75
-
-
33745289074
-
Poly-gamma-glutamate in bacteria
-
Candela T Fouet A (2006) Poly-gamma-glutamate in bacteria. Mol Microbiol 60 : 1091 1098.
-
(2006)
Mol Microbiol
, vol.60
, pp. 1091-1098
-
-
Candela, T.1
Fouet, A.2
-
76
-
-
0024333129
-
(3-Amino-2-oxoalkyl)phosphonic acids and their analogues as novel inhibitors of d-alanine : dd-alanine ligase
-
Chakravarty PK, Greenlee WJ, Parsons WH, Patchett AA, Combs P, Roth A, Busch RD Mellin TN (1989) (3-Amino-2-oxoalkyl)phosphonic acids and their analogues as novel inhibitors of d-alanine : d-alanine ligase. J Med Chem 32 : 1886 1890.
-
(1989)
J Med Chem
, vol.32
, pp. 1886-1890
-
-
Chakravarty, P.K.1
Greenlee, W.J.2
Parsons, W.H.3
Patchett, A.A.4
Combs, P.5
Roth, A.6
Busch, R.D.7
Mellin, T.N.8
-
77
-
-
0020972790
-
Chloralanyl and propargylglycyl dipeptides. Suicide substrate containing antibacterials
-
Cheung KS, Wasserman SA, Dudek E, Lerner SA Johnston M (1983) Chloralanyl and propargylglycyl dipeptides. Suicide substrate containing antibacterials. J Med Chem 26 : 1733 1741.
-
(1983)
J Med Chem
, vol.26
, pp. 1733-1741
-
-
Cheung, K.S.1
Wasserman, S.A.2
Dudek, E.3
Lerner, S.A.4
Johnston, M.5
-
78
-
-
0022447837
-
Chloroalanyl antibiotic peptides: Antagonism of their antimicrobial effects by l-alanine and l-alanyl peptides in Gram-negative bacteria
-
Cheung KS, Boisvert W, Lerner SA Johnston M (1986) Chloroalanyl antibiotic peptides: antagonism of their antimicrobial effects by l-alanine and l-alanyl peptides in Gram-negative bacteria. J Med Chem 29 : 2060 2068.
-
(1986)
J Med Chem
, vol.29
, pp. 2060-2068
-
-
Cheung, K.S.1
Boisvert, W.2
Lerner, S.A.3
Johnston, M.4
-
79
-
-
0021151609
-
Anticapsin, an active-site directed irreversible inhibitor of glucosamine 6-phosphate synthetase from Escherichia coli
-
Chmara H, Zähner H Borowski E (1984) Anticapsin, an active-site directed irreversible inhibitor of glucosamine 6-phosphate synthetase from Escherichia coli. J Antibiotics 37 : 1038 1043.
-
(1984)
J Antibiotics
, vol.37
, pp. 1038-1043
-
-
Chmara, H.1
Zähner, H.2
Borowski, E.3
-
80
-
-
0022510896
-
Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT2 by fumaroyl diaminopropanoic acid derivatives, a novel group of glutamine analogs
-
Chmara H, Andruszkiewicz R Borowski E (1985) Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT2 by fumaroyl diaminopropanoic acid derivatives, a novel group of glutamine analogs. Biochim Biophys Acta 870 : 357 366.
-
(1985)
Biochim Biophys Acta
, vol.870
, pp. 357-366
-
-
Chmara, H.1
Andruszkiewicz, R.2
Borowski, E.3
-
81
-
-
0028029573
-
Bacterial glutamate racemase has high sequence similarity with myoglobins and forms an equimolar inactive complex with hemin
-
Choi SY, Esaki N, Ashiuchi M, Yoshimura T Soda K (1994) Bacterial glutamate racemase has high sequence similarity with myoglobins and forms an equimolar inactive complex with hemin. Proc Natl Acad Sci USA 91 : 10144 10147.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10144-10147
-
-
Choi, S.Y.1
Esaki, N.2
Ashiuchi, M.3
Yoshimura, T.4
Soda, K.5
-
82
-
-
0031734732
-
Antibiotics, peptidoglycan synthesis and genomics: The chlamydial anomaly revisited
-
Chopra I, Storey C, Falla JT Pearce JH (1998) Antibiotics, peptidoglycan synthesis and genomics: the chlamydial anomaly revisited. Microbiology 144 : 2673 2678.
-
(1998)
Microbiology
, vol.144
, pp. 2673-2678
-
-
Chopra, I.1
Storey, C.2
Falla, J.T.3
Pearce, J.H.4
-
83
-
-
33749852183
-
An ultraefficient affinity-based high-throughout screening process: Application to bacterial cell wall biosynthesis enzyme MurF
-
Comess KM, Schurdak ME, Voorbach MJ et al 2006) An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF. J Biomol Screen 11 : 743 754.
-
(2006)
J Biomol Screen
, vol.11
, pp. 743-754
-
-
Comess, K.M.1
Schurdak, M.E.2
Voorbach, M.J.3
Al, E.4
-
84
-
-
0031576984
-
+ binding to perdeuterated MurB: Backbone atom NMR assignments and chemical-shift changes
-
+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes. J Mol Biol 267 : 1223 1246.
-
(1997)
J Mol Biol
, vol.267
, pp. 1223-1246
-
-
Constantine, K.L.1
Mueller, L.2
Goldfarb, V.3
Wittekind, M.4
Metzler, W.J.5
Yanchunas Jr., J.6
Robertson, J.G.7
Malley, M.F.8
Friedrichs, M.S.9
Farmerii., B.T.10
-
86
-
-
0030087892
-
The DAP pathway of lysine as a target for antimicrobial agents
-
Cox RJ (1996) The DAP pathway of lysine as a target for antimicrobial agents. Nat Prod Rep 13 : 29 43.
-
(1996)
Nat Prod Rep
, vol.13
, pp. 29-43
-
-
Cox, R.J.1
-
87
-
-
0034076849
-
Bacterial diaminopimelate metabolism as a target for antibiotic design
-
Cox RJ, Sutherland A Vederas JC (2000) Bacterial diaminopimelate metabolism as a target for antibiotic design. Bioorg Med Chem 8 : 843 871.
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 843-871
-
-
Cox, R.J.1
Sutherland, A.2
Vederas, J.C.3
-
89
-
-
0026664620
-
The crystal structure of muscle phosphoglucomutase refined at 2.7 angstrom resolution
-
Dai JB, Liu Y, Ray WJ Jr. Konno M (1992) The crystal structure of muscle phosphoglucomutase refined at 2.7 angstrom resolution. J Biol Chem 267 : 6322 6337.
-
(1992)
J Biol Chem
, vol.267
, pp. 6322-6337
-
-
Dai, J.B.1
Liu, Y.2
Ray Jr., W.J.3
Konno, M.4
-
90
-
-
0027411732
-
DNA sequence of the murE-murD region of Bacillus subtilis 168
-
Daniel RA Errington J (1993) DNA sequence of the murE-murD region of Bacillus subtilis 168. J Gen Microbiol 139 : 361 370.
-
(1993)
J Gen Microbiol
, vol.139
, pp. 361-370
-
-
Daniel, R.A.1
Errington, J.2
-
91
-
-
0024290414
-
Isolation, cloning, and sequencing of the Salmonella typhimurium ddlA gene with purification and characterization of its product, d-alanine : dd-alanine ligase (ADP forming)
-
Daub E, Zawadzke LE, Botstein D Walsh CT (1988) Isolation, cloning, and sequencing of the Salmonella typhimurium ddlA gene with purification and characterization of its product, d-alanine : d-alanine ligase (ADP forming). Biochemistry 27 : 3701 3708.
-
(1988)
Biochemistry
, vol.27
, pp. 3701-3708
-
-
Daub, E.1
Zawadzke, L.E.2
Botstein, D.3
Walsh, C.T.4
-
92
-
-
0037179637
-
4-Substituted d-glutamic acid analogues: The first potent inhibitors of glutamate racemase (MurI) enzyme with antibacterial activity
-
de Dios A, Prieto L, Martin JA et al 2002) 4-Substituted d-glutamic acid analogues: the first potent inhibitors of glutamate racemase (MurI) enzyme with antibacterial activity. J Med Chem 45 : 4559 4570.
-
(2002)
J Med Chem
, vol.45
, pp. 4559-4570
-
-
De Dios, A.1
Prieto, L.2
Martin, J.A.3
Al, E.4
-
93
-
-
0032741590
-
Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis
-
De Smet KA, Kempsell KE, Gallagher A, Duncan K Young DB (1999) Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis. Microbiology 145 : 3177 3184.
-
(1999)
Microbiology
, vol.145
, pp. 3177-3184
-
-
De Smet, K.A.1
Kempsell, K.E.2
Gallagher, A.3
Duncan, K.4
Young, D.B.5
-
94
-
-
39149091125
-
-
Etude du mécanisme réactionnel des Mur synthétases, enzymes impliquées dans la biosynthèse du peptidoglycane bactérien. Ph.D. Thesis, Université Paris-Sud, Orsay, France.
-
Dementin S (2001) Etude du mécanisme réactionnel des Mur synthétases, enzymes impliquées dans la biosynthèse du peptidoglycane bactérien. Ph.D. Thesis, Université Paris-Sud, Orsay, France.
-
(2001)
-
-
Dementin, S.1
-
95
-
-
0035166706
-
Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments
-
Dementin S, Bouhss A, Auger G, Parquet C, Mengin-Lecreulx D, Dideberg O, van Heijenoort J Blanot D (2001) Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments. Eur J Biochem 268 : 5800 5807.
-
(2001)
Eur J Biochem
, vol.268
, pp. 5800-5807
-
-
Dementin, S.1
Bouhss, A.2
Auger, G.3
Parquet, C.4
Mengin-Lecreulx, D.5
Dideberg, O.6
Van Heijenoort, J.7
Blanot, D.8
-
96
-
-
33845509079
-
Structure of Escherichia coli UDP-N-acetylmuramoyl: L-alanine ligase (MurC)
-
Deva T, Baker EN, Squire CJ Smith CA (2006) Structure of Escherichia coli UDP-N-acetylmuramoyl: l-alanine ligase (MurC). Acta Cryst D62 : 1466 1474.
-
(2006)
Acta Cryst
, vol.62
, pp. 1466-1474
-
-
Deva, T.1
Baker, E.N.2
Squire, C.J.3
Smith, C.A.4
-
97
-
-
0036256037
-
An array of target-specific screening strains for antibacterial discovery
-
DeVito JA, Mills JA, Liu VG et al 2002) An array of target-specific screening strains for antibacterial discovery. Nat Biotechnol 20 : 478 483.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 478-483
-
-
Devito, J.A.1
Mills, J.A.2
Liu, V.G.3
Al, E.4
-
98
-
-
0029007512
-
Steady-state kinetic mechanism of Escherichia coli UDP-N- acetylenolpyruvylglucosamine reductase
-
Dhalla AM, Yanchunas J Jr., Ho HT, Falk PJ, Villafranca JJ Robertson JG (1995) Steady-state kinetic mechanism of Escherichia coli UDP-N- acetylenolpyruvylglucosamine reductase. Biochemistry 34 : 5390 5402.
-
(1995)
Biochemistry
, vol.34
, pp. 5390-5402
-
-
Dhalla, A.M.1
Yanchunas Jr., J.2
Ho, H.T.3
Falk, P.J.4
Villafranca, J.J.5
Robertson, J.G.6
-
100
-
-
34447526743
-
Functional comparison of the two Bacillus anthracis glutamate racemases
-
Dodd D, Reese JG, Louer CR, Ballard JD, Spies MA Blanke SR (2007) Functional comparison of the two Bacillus anthracis glutamate racemases. J Bacteriol 189 : 5265 5275.
-
(2007)
J Bacteriol
, vol.189
, pp. 5265-5275
-
-
Dodd, D.1
Reese, J.G.2
Louer, C.R.3
Ballard, J.D.4
Spies, M.A.5
Blanke, S.R.6
-
101
-
-
0027212678
-
The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity
-
Doublet P, van Heijenoort J, Bohin J-P Mengin-Lecreulx D (1993) The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity. J Bacteriol 175 : 2970 2979.
-
(1993)
J Bacteriol
, vol.175
, pp. 2970-2979
-
-
Doublet, P.1
Van Heijenoort, J.2
Bohin, J.-P.3
Mengin-Lecreulx, D.4
-
102
-
-
0028198913
-
The glutamate racemase activity from Escherichia coli is regulated by peptidoglycan precursor UDP-N-acetylmuramoyl-l-alanine
-
Doublet P, van Heijenoort J Mengin-Lecreulx D (1994) The glutamate racemase activity from Escherichia coli is regulated by peptidoglycan precursor UDP-N-acetylmuramoyl-l-alanine. Biochemistry 33 : 5285 5290.
-
(1994)
Biochemistry
, vol.33
, pp. 5285-5290
-
-
Doublet, P.1
Van Heijenoort, J.2
Mengin-Lecreulx, D.3
-
103
-
-
0029764197
-
Regulation of the glutamate racemase of Escherichia coli investigated by site-directed mutagenesis
-
Doublet P, van Heijenoort J Mengin-Lecreulx D (1996) Regulation of the glutamate racemase of Escherichia coli investigated by site-directed mutagenesis. Microb Drug Resist 2 : 43 49.
-
(1996)
Microb Drug Resist
, vol.2
, pp. 43-49
-
-
Doublet, P.1
Van Heijenoort, J.2
Mengin-Lecreulx, D.3
-
104
-
-
0033939999
-
Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in Gram-positive bacteria
-
Du W, Brown JR, Sylvester DR, Huang J, Chalker AF, So SY, Holmes DJ, Payne DJ Wallis NG (2000) Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in Gram-positive bacteria. J Bacteriol 182 : 4146 4152.
-
(2000)
J Bacteriol
, vol.182
, pp. 4146-4152
-
-
Du, W.1
Brown, J.R.2
Sylvester, D.R.3
Huang, J.4
Chalker, A.F.5
So, S.Y.6
Holmes, D.J.7
Payne, D.J.8
Wallis, N.G.9
-
105
-
-
0024290408
-
ATP-dependent inactivation and slow binding inhibition of Salmonella typhimurium d-alanine : dd-alanine ligase (ADP) by (aminoalkyl)phosphinate and aminophosphonate analogues of d-alanine
-
Duncan K Walsh CT (1988) ATP-dependent inactivation and slow binding inhibition of Salmonella typhimurium d-alanine : d-alanine ligase (ADP) by (aminoalkyl)phosphinate and aminophosphonate analogues of d-alanine. Biochemistry 27 : 3709 3714.
-
(1988)
Biochemistry
, vol.27
, pp. 3709-3714
-
-
Duncan, K.1
Walsh, C.T.2
-
106
-
-
0024523731
-
(1-Aminoethyl)boronic acid: A novel inhibitor for Bacillus stearothermophilus alanine racemase and Salmonella typhimurium d-alanine : dalanine ligase (ADP-forming)
-
Duncan K, Faraci WS, Matteson DS Walsh CT (1989) (1-Aminoethyl)boronic acid: a novel inhibitor for Bacillus stearothermophilus alanine racemase and Salmonella typhimurium d-alanine : d-alanine ligase (ADP-forming). Biochemistry 28 : 3541 3549.
-
(1989)
Biochemistry
, vol.28
, pp. 3541-3549
-
-
Duncan, K.1
Faraci, W.S.2
Matteson, D.S.3
Walsh, C.T.4
-
107
-
-
0025210655
-
Purification and characterization of the d-alanyl-d-alanine-adding enzyme from Escherichia coli
-
Duncan K, van Heijenoort J Walsh CT (1990) Purification and characterization of the d-alanyl-d-alanine-adding enzyme from Escherichia coli. Biochemistry 29 : 2379 2386.
-
(1990)
Biochemistry
, vol.29
, pp. 2379-2386
-
-
Duncan, K.1
Van Heijenoort, J.2
Walsh, C.T.3
-
108
-
-
2342623377
-
Biochemical characterization of an inhibitor of Escherichia coli UDP-N-acetylmuramyl-l-alanine ligase
-
Ehmann DE, Demeritt JE, Hull KG Fisher SL (2004) Biochemical characterization of an inhibitor of Escherichia coli UDP-N-acetylmuramyl-l- alanine ligase. Biochim Biophys Acta 1698 : 167 174.
-
(2004)
Biochim Biophys Acta
, vol.1698
, pp. 167-174
-
-
Ehmann, D.E.1
Demeritt, J.E.2
Hull, K.G.3
Fisher, S.L.4
-
109
-
-
0029678335
-
Synthesis and evaluation of inhibitors of bacterial d-alanine : dd-alanine ligases
-
Ellsworth BA, Tom NJ Bartlett PA (1996) Synthesis and evaluation of inhibitors of bacterial d-alanine : d-alanine ligases. Chem Biol 3 : 37 44.
-
(1996)
Chem Biol
, vol.3
, pp. 37-44
-
-
Ellsworth, B.A.1
Tom, N.J.2
Bartlett, P.A.3
-
110
-
-
0033981615
-
Cloning, over-expression and purification of Pseudomonas aeruginosa murC encoding uridine diphosphate N-acetylmuramate: L-alanine ligase
-
El Zoeiby A, Sanschagrin F, Lamoureux J, Darveau A Levesque RC (2000) Cloning, over-expression and purification of Pseudomonas aeruginosa murC encoding uridine diphosphate N-acetylmuramate: l-alanine ligase. FEMS Microbiol Lett 183 : 281 288.
-
(2000)
FEMS Microbiol Lett
, vol.183
, pp. 281-288
-
-
El Zoeiby, A.1
Sanschagrin, F.2
Lamoureux, J.3
Darveau, A.4
Levesque, R.C.5
-
111
-
-
0035943137
-
In vitro reconstruction of the biosynthetic pathway of peptidoglycan cytoplasmic precursor in Pseudomonas aeruginosa
-
El Zoeiby A, Sanschagrin F, Havugimana PC, Garnier A Levesque RC (2001) In vitro reconstruction of the biosynthetic pathway of peptidoglycan cytoplasmic precursor in Pseudomonas aeruginosa. FEMS Microbiol Lett 201 : 229 235.
-
(2001)
FEMS Microbiol Lett
, vol.201
, pp. 229-235
-
-
El Zoeiby, A.1
Sanschagrin, F.2
Havugimana, P.C.3
Garnier, A.4
Levesque, R.C.5
-
112
-
-
0037223505
-
Structure and function of the Mur enzymes: Development of novel inhibitors
-
El Zoeiby A, Sanschagrin F Levesque RC (2003a) Structure and function of the Mur enzymes: development of novel inhibitors. Mol Microbiol 47 : 1 12.
-
(2003)
Mol Microbiol
, vol.47
, pp. 1-12
-
-
El Zoeiby, A.1
Sanschagrin, F.2
Levesque, R.C.3
-
113
-
-
0037339206
-
Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries
-
El Zoeiby A, Sanschagrin F, Darveau A, Brisson J-R Levesque RC (2003b) Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries. J Antimicrob Chemother 51 : 531 543.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 531-543
-
-
El Zoeiby, A.1
Sanschagrin, F.2
Darveau, A.3
Brisson, J.-R.4
Levesque, R.C.5
-
114
-
-
0030474933
-
Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate: L-alanine ligase
-
Emanuele JJ Jr., Jin H, Jacobson BL, Chang CY, Einspahr HM Villafranca JJ (1996) Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate: l-alanine ligase. Prot Sci 5 : 2566 2574.
-
(1996)
Prot Sci
, vol.5
, pp. 2566-2574
-
-
Emanuele Jr., J.J.1
Jin, H.2
Jacobson, B.L.3
Chang, C.Y.4
Einspahr, H.M.5
Villafranca, J.J.6
-
115
-
-
0030960337
-
Evaluation of the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate: L-alanine ligase
-
Emanuele JJ Jr., Jin H, Yanchunas J Villafranca JJ (1997) Evaluation of the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate: l-alanine ligase. Biochemistry 36 : 7264 7271.
-
(1997)
Biochemistry
, vol.36
, pp. 7264-7271
-
-
Emanuele Jr., J.J.1
Jin, H.2
Yanchunas, J.3
Villafranca, J.J.4
-
116
-
-
0023657752
-
1-Aminocyclopropanephosphonate: Time-dependent inactivation of 1-aminocyclopropanecarboxylate deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior
-
Erion MD Walsh CT (1987) 1-Aminocyclopropanephosphonate: time-dependent inactivation of 1-aminocyclopropanecarboxylate deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior. Biochemistry 26 : 3417 3425.
-
(1987)
Biochemistry
, vol.26
, pp. 3417-3425
-
-
Erion, M.D.1
Walsh, C.T.2
-
117
-
-
0022536214
-
Biosynthetic alanine racemase of Salmonella typhimurium: Purification and characterization of the enzyme encoded by the alr gene
-
Esaki N Walsh CT (1986) Biosynthetic alanine racemase of Salmonella typhimurium: purification and characterization of the enzyme encoded by the alr gene. Biochemistry 25 : 3261 3267.
-
(1986)
Biochemistry
, vol.25
, pp. 3261-3267
-
-
Esaki, N.1
Walsh, C.T.2
-
118
-
-
0034257036
-
Comparative X-ray analysis of the un-liganded fosfomycin-target murA
-
Eschenburg S Schönbrunn E (2000) Comparative X-ray analysis of the un-liganded fosfomycin-target murA. Proteins 40 : 290 298.
-
(2000)
Proteins
, vol.40
, pp. 290-298
-
-
Eschenburg, S.1
Schönbrunn, E.2
-
119
-
-
1542467723
-
A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states
-
Eschenburg S, Kabsch W, Healy ML Schönbrunn E (2003) A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states. J Biol Chem 278 : 49215 49222.
-
(2003)
J Biol Chem
, vol.278
, pp. 49215-49222
-
-
Eschenburg, S.1
Kabsch, W.2
Healy, M.L.3
Schönbrunn, E.4
-
120
-
-
13544252827
-
115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release
-
115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem 280 : 3757 3763.
-
(2005)
J Biol Chem
, vol.280
, pp. 3757-3763
-
-
Eschenburg, S.1
Priestman, M.2
Schönbrunn, E.3
-
121
-
-
17144418885
-
A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA)
-
Eschenburg S, Priestman MA, Abdul-Latif FA, Delachaume C Fassy FE (2005b) A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). J Biol Chem 280 : 14070 14075.
-
(2005)
J Biol Chem
, vol.280
, pp. 14070-14075
-
-
Eschenburg, S.1
Priestman, M.A.2
Abdul-Latif, F.A.3
Delachaume, C.4
Fassy, F.E.5
-
122
-
-
0031007336
-
Conditionally lethal Escherichia coli murein mutants contain point defects that map to regions conserved among murein and folyl poly-γ-glutamate ligases: Identification of a ligase superfamily
-
Eveland SS, Pompliano DL Anderson MS (1997) Conditionally lethal Escherichia coli murein mutants contain point defects that map to regions conserved among murein and folyl poly-γ-glutamate ligases: identification of a ligase superfamily. Biochemistry 36 : 6223 6229.
-
(1997)
Biochemistry
, vol.36
, pp. 6223-6229
-
-
Eveland, S.S.1
Pompliano, D.L.2
Anderson, M.S.3
-
123
-
-
0030020538
-
Biochemical evidence for the formation of a covalent acyl-phosphate linkage between UDP-N-acetylmuramate and ATP in the Escherichia coli UDP-N-acetylmuramate: L-alanine ligase-catalyzed reaction
-
Falk PJ, Ervin KM, Volk KS Ho H-T (1996) Biochemical evidence for the formation of a covalent acyl-phosphate linkage between UDP-N-acetylmuramate and ATP in the Escherichia coli UDP-N-acetylmuramate: l-alanine ligase-catalyzed reaction. Biochemistry 35 : 1417 1422.
-
(1996)
Biochemistry
, vol.35
, pp. 1417-1422
-
-
Falk, P.J.1
Ervin, K.M.2
Volk, K.S.3
Ho, H.-T.4
-
124
-
-
0028151598
-
Vancomycin resistance: Structure of d-alanine : dligase at 2.3 resolutiÅon
-
Fan C, Moews PC, Walsh CT Knox JR (1994) Vancomycin resistance: structure of d-alanine : d-alanine ligase at 2.3 Å resolution. Science 266 : 439 443.
-
(1994)
Science
, vol.266
, pp. 439-443
-
-
Fan, C.1
Moews, P.C.2
Walsh, C.T.3
Knox, J.R.4
-
125
-
-
0031020216
-
D-alanine : dd-alanine ligase: Phosphonate and phosphinate intermediates with wild type and the Y216F mutant
-
Fan C, Park IS, Walsh CT Knox JR (1997) d-alanine : d-alanine ligase: phosphonate and phosphinate intermediates with wild type and the Y216F mutant. Biochemistry 36 : 2531 2538.
-
(1997)
Biochemistry
, vol.36
, pp. 2531-2538
-
-
Fan, C.1
Park, I.S.2
Walsh, C.T.3
Knox, J.R.4
-
126
-
-
0024548243
-
Mechanism of inactivation of alanine racemase by β, β, β-trifluoroalanine
-
Faraci WS Walsh CT (1989) Mechanism of inactivation of alanine racemase by β, β, β-trifluoroalanine. Biochemistry 28 : 431 437.
-
(1989)
Biochemistry
, vol.28
, pp. 431-437
-
-
Faraci, W.S.1
Walsh, C.T.2
-
127
-
-
0030457156
-
+ binding site on the MurB enzyme by NMR
-
+ binding site on the MurB enzyme by NMR. Nat Struct Biol 3 : 995 997.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 995-997
-
-
Farmerii., B.T.1
Constantine, K.L.2
Goldfarb, V.3
Friedrichs, M.S.4
Wittekind, M.5
Yanchunas Jr., J.6
Robertson, J.G.7
Mueller, L.8
-
128
-
-
0037952855
-
A side reaction of alanine racemase: Transamination of cycloserine
-
Fenn TD, Stamper GF, Morollo AA Ringe D (2003) A side reaction of alanine racemase: transamination of cycloserine. Biochemistry 42 : 5775 5783.
-
(2003)
Biochemistry
, vol.42
, pp. 5775-5783
-
-
Fenn, T.D.1
Stamper, G.F.2
Morollo, A.A.3
Ringe, D.4
-
129
-
-
16844378698
-
Effect of a Y265F mutant on the transamination-based cycloserine inactivation of alanine racemase
-
Fenn TD, Holyoak T, Stamper GF Ringe D (2005) Effect of a Y265F mutant on the transamination-based cycloserine inactivation of alanine racemase. Biochemistry 44 : 5317 5327.
-
(2005)
Biochemistry
, vol.44
, pp. 5317-5327
-
-
Fenn, T.D.1
Holyoak, T.2
Stamper, G.F.3
Ringe, D.4
-
130
-
-
34250194661
-
Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): Molecular dynamics simulations and kinetic studies of protein mutants
-
Floquet N, Mouilleron S, Daher R, Maigret B, Badet B Badet-Denisot MA (2007a) Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): molecular dynamics simulations and kinetic studies of protein mutants. FEBS Lett 581 : 2981 2987.
-
(2007)
FEBS Lett
, vol.581
, pp. 2981-2987
-
-
Floquet, N.1
Mouilleron, S.2
Daher, R.3
Maigret, B.4
Badet, B.5
Badet-Denisot, M.A.6
-
131
-
-
33847653392
-
Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations
-
Floquet N, Richez C, Durand P, Maigret B, Badet B Badet-Denisot MA (2007b) Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations. Bioorg Med Chem Lett 17 : 1966 1970.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 1966-1970
-
-
Floquet, N.1
Richez, C.2
Durand, P.3
Maigret, B.4
Badet, B.5
Badet-Denisot, M.A.6
-
132
-
-
0019578458
-
Reverse-phase high-pressure liquid chromatography of uridine diphosphate N-acetylmuramyl peptide precursors of bacterial cell wall peptidoglycan
-
Flouret B, Mengin-Lecreulx D van Heijenoort J (1981) Reverse-phase high-pressure liquid chromatography of uridine diphosphate N-acetylmuramyl peptide precursors of bacterial cell wall peptidoglycan. Anal Biochem 114 : 59 63.
-
(1981)
Anal Biochem
, vol.114
, pp. 59-63
-
-
Flouret, B.1
Mengin-Lecreulx, D.2
Van Heijenoort, J.3
-
133
-
-
0031859365
-
Characterization of the genes encoding d-amino acid transaminase and glutamate racemase, two d-glutamate biosynthetic enzymes of Bacillus sphaericus ATCC
-
10208.
-
Fotheringham IG, Bledig SA Taylor PP (1998) Characterization of the genes encoding d-amino acid transaminase and glutamate racemase, two d-glutamate biosynthetic enzymes of Bacillus sphaericus ATCC 10208. J Bacteriol 180 : 4319 4323.
-
(1998)
J Bacteriol
, vol.180
, pp. 4319-4323
-
-
Fotheringham, I.G.1
Bledig, S.A.2
Taylor, P.P.3
-
134
-
-
0346252635
-
Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis
-
Francisco GD, Li Z, Albright JD et al 2004) Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis. Bioorg Med Chem Lett 14 : 235 238.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 235-238
-
-
Francisco, G.D.1
Li, Z.2
Albright, J.D.3
Al, E.4
-
135
-
-
0027263160
-
Purification, cloning, and cofactor independence of glutamate racemase from Lactobacillus
-
Gallo KA Knowles JR (1993) Purification, cloning, and cofactor independence of glutamate racemase from Lactobacillus. Biochemistry 32 : 3981 3990.
-
(1993)
Biochemistry
, vol.32
, pp. 3981-3990
-
-
Gallo, K.A.1
Knowles, J.R.2
-
136
-
-
0027299709
-
Mechanism of the reaction catalyzed by glutamate racemase
-
Gallo KA, Tanner ME Knowles JR (1993) Mechanism of the reaction catalyzed by glutamate racemase. Biochemistry 32 : 3991 3997.
-
(1993)
Biochemistry
, vol.32
, pp. 3991-3997
-
-
Gallo, K.A.1
Tanner, M.E.2
Knowles, J.R.3
-
137
-
-
0031467818
-
A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/ thiol ligase activity
-
Galperin MY Koonin EV (1997) A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/thiol ligase activity. Protein Sci 6 : 2639 2643.
-
(1997)
Protein Sci
, vol.6
, pp. 2639-2643
-
-
Galperin, M.Y.1
Koonin, E.V.2
-
138
-
-
0032493338
-
Inhibitors of the bacterial cell wall biosynthesis enzyme MurD
-
Gegnas LD, Waddell ST, Chabin RM, Reddy S Wong KK (1998) Inhibitors of the bacterial cell wall biosynthesis enzyme MurD. Bioorg Med Chem Lett 8 : 1643 1648.
-
(1998)
Bioorg Med Chem Lett
, vol.8
, pp. 1643-1648
-
-
Gegnas, L.D.1
Waddell, S.T.2
Chabin, R.M.3
Reddy, S.4
Wong, K.K.5
-
139
-
-
0030051742
-
Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli
-
Gehring AM, Lees WJ, Mindiola DJ, Walsh CT Brown ED (1996) Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli. Biochemistry 35 : 579 585.
-
(1996)
Biochemistry
, vol.35
, pp. 579-585
-
-
Gehring, A.M.1
Lees, W.J.2
Mindiola, D.J.3
Walsh, C.T.4
Brown, E.D.5
-
140
-
-
0142180157
-
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
-
Girardin SE, Travassos LH, Hervé M, Blanot D, Boneca IG, Philpott DJ, Sansonetti PJ Mengin-Lecreulx D (2003) Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem 278 : 41702 41708.
-
(2003)
J Biol Chem
, vol.278
, pp. 41702-41708
-
-
Girardin, S.E.1
Travassos, L.H.2
Hervé, M.3
Blanot, D.4
Boneca, I.G.5
Philpott, D.J.6
Sansonetti, P.J.7
Mengin-Lecreulx, D.8
-
141
-
-
0032993693
-
GlmM operon and methicillin-resistant glmM suppressor mutants in Staphylococcus aureus
-
Glanzmann P, Gustafson J, Komatsuzawa H, Ohta K Berger-Bächi B (1999) glmM operon and methicillin-resistant glmM suppressor mutants in Staphylococcus aureus. Antimicrob Agents Chemother 43 : 240 245.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 240-245
-
-
Glanzmann, P.1
Gustafson, J.2
Komatsuzawa, H.3
Ohta, K.4
Berger-Bächi, B.5
-
142
-
-
0030985410
-
The inhibition of glutamate racemase by D-N-hydroxyglutamate
-
Glavas S Tanner ME (1997) The inhibition of glutamate racemase by D-N-hydroxyglutamate. Bioorg Med Chem Lett 7 : 2265 2270.
-
(1997)
Bioorg Med Chem Lett
, vol.7
, pp. 2265-2270
-
-
Glavas, S.1
Tanner, M.E.2
-
143
-
-
0033616629
-
Catalytic acid/base residues of glutamate racemase
-
Glavas S Tanner ME (1999) Catalytic acid/base residues of glutamate racemase. Biochemistry 38 : 4106 4113.
-
(1999)
Biochemistry
, vol.38
, pp. 4106-4113
-
-
Glavas, S.1
Tanner, M.E.2
-
144
-
-
0035967535
-
Active site residues of glutamate racemase
-
Glavas S Tanner ME (2001) Active site residues of glutamate racemase. Biochemistry 40 : 6199 6204.
-
(2001)
Biochemistry
, vol.40
, pp. 6199-6204
-
-
Glavas, S.1
Tanner, M.E.2
-
145
-
-
0035044363
-
Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the d-glutamic acid-adding enzyme
-
Gobec S, Urleb U, Auger G Blanot D (2001) Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the d-glutamic acid-adding enzyme. Pharmazie 56 : 295 297.
-
(2001)
Pharmazie
, vol.56
, pp. 295-297
-
-
Gobec, S.1
Urleb, U.2
Auger, G.3
Blanot, D.4
-
146
-
-
0024594268
-
Glucosamine-6-phosphate synthase from Escherichia coli: Mechanism of the reaction at the fructose 6-phosphate binding site
-
Golinelli-Pimpaneau B, Le Goffic F Badet B (1989) Glucosamine-6-phosphate synthase from Escherichia coli: mechanism of the reaction at the fructose 6-phosphate binding site. J Am Chem Soc 111 : 3029 3034.
-
(1989)
J Am Chem Soc
, vol.111
, pp. 3029-3034
-
-
Golinelli-Pimpaneau, B.1
Le Goffic, F.2
Badet, B.3
-
147
-
-
0035815667
-
Crystal structure of the UDP-N-acetylmuramoyl-l-alanyl-d-glutamate: Meso-diaminopimelate ligase from Escherichia coli
-
Gordon E, Flouret B, Chantalat L, van Heijenoort J, Mengin-Lecreulx D Dideberg O (2001) Crystal structure of the UDP-N-acetylmuramoyl-l-alanyl-d- glutamate: meso-diaminopimelate ligase from Escherichia coli. J Biol Chem 276 : 10999 11006.
-
(2001)
J Biol Chem
, vol.276
, pp. 10999-11006
-
-
Gordon, E.1
Flouret, B.2
Chantalat, L.3
Van Heijenoort, J.4
Mengin-Lecreulx, D.5
Dideberg, O.6
-
149
-
-
0030066560
-
Overexpression, purification, and characterization of UDP-N-acetylmuramyl: L-alanine ligase from Escherichia coli
-
Gubler M, Appoldt Y Keck W (1996) Overexpression, purification, and characterization of UDP-N-acetylmuramyl: l-alanine ligase from Escherichia coli. J Bacteriol 178 : 906 910.
-
(1996)
J Bacteriol
, vol.178
, pp. 906-910
-
-
Gubler, M.1
Appoldt, Y.2
Keck, W.3
-
150
-
-
0017743605
-
On the specificity of the uridine diphospho-N-acetylmuramyl-alanyl-d- glutamic acid: Diamino acid ligase of Bifidobacterium globosum
-
Hammes WP, Neukam R Kandler O (1977) On the specificity of the uridine diphospho-N-acetylmuramyl-alanyl-d-glutamic acid: diamino acid ligase of Bifidobacterium globosum. Arch Microbiol 115 : 95 102.
-
(1977)
Arch Microbiol
, vol.115
, pp. 95-102
-
-
Hammes, W.P.1
Neukam, R.2
Kandler, O.3
-
151
-
-
0034087501
-
Vancomycin resistance in enterococci: Reprogramming of the d-Ala-d-Ala ligases in bacterial peptidoglycan biosynthesis
-
Healy VL, Lessard IA, Roper DI, Knox JR Walsh CT (2000a) Vancomycin resistance in enterococci: reprogramming of the d-Ala-d-Ala ligases in bacterial peptidoglycan biosynthesis. Chem Biol 7 : R109 R119.
-
(2000)
Chem Biol
, vol.7
-
-
Healy, V.L.1
Lessard, I.A.2
Roper, D.I.3
Knox, J.R.4
Walsh, C.T.5
-
152
-
-
0033941894
-
D-Ala-d-X ligases: Evaluation of d-alanyl phosphate intermediate by MIX, PIX and rapid quench studies
-
Healy VL, Mullins LS, Li X, Hall SE, Raushel FM Walsh CT (2000b) d-Ala-d-X ligases: evaluation of d-alanyl phosphate intermediate by MIX, PIX and rapid quench studies. Chem Biol 7 : 505 514.
-
(2000)
Chem Biol
, vol.7
, pp. 505-514
-
-
Healy, V.L.1
Mullins, L.S.2
Li, X.3
Hall, S.E.4
Raushel, F.M.5
Walsh, C.T.6
-
153
-
-
34249816155
-
Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate: L-alanyl-γ-d-glutamyl-meso-diaminopimelate ligase (Mpl)
-
Hervé M, Boniface A, Gobec S, Blanot D Mengin-Lecreulx D (2007) Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate: l-alanyl-γ-d-glutamyl-meso-diaminopimelate ligase (Mpl). J Bacteriol 189 : 3987 3995.
-
(2007)
J Bacteriol
, vol.189
, pp. 3987-3995
-
-
Hervé, M.1
Boniface, A.2
Gobec, S.3
Blanot, D.4
Mengin-Lecreulx, D.5
-
154
-
-
0242490835
-
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate: Amino acid ligase activity
-
Hesse L, Bostock J, Dementin S, Blanot D, Mengin-Lecreulx D Chopra I (2003) Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate: amino acid ligase activity. J Bacteriol 185 : 6507 6512.
-
(2003)
J Bacteriol
, vol.185
, pp. 6507-6512
-
-
Hesse, L.1
Bostock, J.2
Dementin, S.3
Blanot, D.4
Mengin-Lecreulx, D.5
Chopra, I.6
-
156
-
-
0032481622
-
The first total synthesis of bacterial cell wall precursor UDP-N-acetylmuramyl-pentapeptide (Park nucleotide)
-
Hitchcock SA, Eid CN, Aikins JA, Zia-Ebrahimi M Blaszczak LC (1998) The first total synthesis of bacterial cell wall precursor UDP-N-acetylmuramyl- pentapeptide (Park nucleotide). J Am Chem Soc 120 : 1916 1917.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 1916-1917
-
-
Hitchcock, S.A.1
Eid, C.N.2
Aikins, J.A.3
Zia-Ebrahimi, M.4
Blaszczak, L.C.5
-
157
-
-
0028899510
-
UDP-N-acetylmuramyl-l-alanine functions as an activator in the regulation of the Escherichia coli glutamate racemase activity
-
Ho HT, Falk PJ, Ervin KM, Krishnan BS, Discotto LF, Dougherty TJ Pucci MJ (1995) UDP-N-acetylmuramyl-l-alanine functions as an activator in the regulation of the Escherichia coli glutamate racemase activity. Biochemistry 34 : 2464 2470.
-
(1995)
Biochemistry
, vol.34
, pp. 2464-2470
-
-
Ho, H.T.1
Falk, P.J.2
Ervin, K.M.3
Krishnan, B.S.4
Discotto, L.F.5
Dougherty, T.J.6
Pucci, M.J.7
-
158
-
-
0028271352
-
Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase
-
Hofmann M, Boles E Zimmermann FK (1994) Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase. Eur J Biochem 221 : 741 747.
-
(1994)
Eur J Biochem
, vol.221
, pp. 741-747
-
-
Hofmann, M.1
Boles, E.2
Zimmermann, F.K.3
-
159
-
-
12444301738
-
Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD
-
Horton JR, Bostock JM, Chopra I, Hesse L, Phillips SE, Adams DJ, Johnson AP Fishwick CW (2003) Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD. Bioorg Med Chem Lett 13 : 1557 1560.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 1557-1560
-
-
Horton, J.R.1
Bostock, J.M.2
Chopra, I.3
Hesse, L.4
Phillips, S.E.5
Adams, D.J.6
Johnson, A.P.7
Fishwick, C.W.8
-
160
-
-
0026641624
-
Identification of tms-26 as an allele of the gcaD gene, which encodes N-acetylglucosamine 1-phosphate uridyltransferase in Bacillus subtilis
-
Hove-Jensen B (1992) Identification of tms-26 as an allele of the gcaD gene, which encodes N-acetylglucosamine 1-phosphate uridyltransferase in Bacillus subtilis. J Bacteriol 174 : 6852 6856.
-
(1992)
J Bacteriol
, vol.174
, pp. 6852-6856
-
-
Hove-Jensen, B.1
-
161
-
-
0022522022
-
Thermotoga maritima sp. nov. represents a new genus of unique extremely thermophylic eubacteria growing up to 90 °c
-
Huber R, Langworthy TA, König H, Thomm M, Woese CR, Sleytr UB Stetter KO (1986) Thermotoga maritima sp. nov. represents a new genus of unique extremely thermophylic eubacteria growing up to 90 °C. Arch Microbiol 144 : 324 333.
-
(1986)
Arch Microbiol
, vol.144
, pp. 324-333
-
-
Huber, R.1
Langworthy, T.A.2
König, H.3
Thomm, M.4
Woese, C.R.5
Sleytr, U.B.6
Stetter, K.O.7
-
162
-
-
33749531892
-
A new approach towards peptidosulfonamides: Synthesis of potential inhibitors of bacterial peptidoglycan biosynthesis enzymes MurD and MurE
-
Humljan J, Kotnik M, Boniface A, Šolmajer T, Urleb U, Blanot D Gobec S (2006) A new approach towards peptidosulfonamides: synthesis of potential inhibitors of bacterial peptidoglycan biosynthesis enzymes MurD and MurE. Tetrahedron 62 : 10980 10988.
-
(2006)
Tetrahedron
, vol.62
, pp. 10980-10988
-
-
Humljan, J.1
Kotnik, M.2
Boniface, A.3
Šolmajer, T.4
Urleb, U.5
Blanot, D.6
Gobec, S.7
-
163
-
-
34250692637
-
Inhibition of lysine biosynthesis: An evolving antibiotic strategy
-
Hutton CA, Perugini MA Gerrard JA (2007) Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol BioSyst 3 : 458 465.
-
(2007)
Mol BioSyst
, vol.3
, pp. 458-465
-
-
Hutton, C.A.1
Perugini, M.A.2
Gerrard, J.A.3
-
164
-
-
0034661449
-
Purification and characterization of glutamine: Fructose 6-phosphate amidotransferase from rat liver
-
Huynh QK, Gulve EA Dian T (2000) Purification and characterization of glutamine: fructose 6-phosphate amidotransferase from rat liver. Arch Biochem Biophys 379 : 307 313.
-
(2000)
Arch Biochem Biophys
, vol.379
, pp. 307-313
-
-
Huynh, Q.K.1
Gulve, E.A.2
Dian, T.3
-
165
-
-
0032915050
-
Structure and mechanism of glutamate racemase from Aquifex pyrophilus
-
Hwang KY, Cho C-S, Kim SS, Sung H-C, Yu YG Cho Y (1999) Structure and mechanism of glutamate racemase from Aquifex pyrophilus. Nat Struct Biol 6 : 422 426.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 422-426
-
-
Hwang, K.Y.1
Cho, C.-S.2
Kim, S.S.3
Sung, H.-C.4
Yu, Y.G.5
Cho, Y.6
-
166
-
-
0022452427
-
Thermostable alanine racemase from Bacillus stearothermophilus: Molecular cloning of the gene, enzyme purification, and characterization
-
Inagaki K, Tanizawa K, Badet B, Walsh CT, Tanaka H Soda K (1986) Thermostable alanine racemase from Bacillus stearothermophilus: molecular cloning of the gene, enzyme purification, and characterization. Biochemistry 25 : 3268 3274.
-
(1986)
Biochemistry
, vol.25
, pp. 3268-3274
-
-
Inagaki, K.1
Tanizawa, K.2
Badet, B.3
Walsh, C.T.4
Tanaka, H.5
Soda, K.6
-
167
-
-
0030586024
-
Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: Evidence from the 1.8 Å crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase
-
Isupov MN, Obmolova G, Butterworth S, Badet-Denisot MA, Badet B, Polikarpov I, Littlechild JA Teplyakov A (1996) Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 Å crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase. Structure 4 : 801 810.
-
(1996)
Structure
, vol.4
, pp. 801-810
-
-
Isupov, M.N.1
Obmolova, G.2
Butterworth, S.3
Badet-Denisot, M.A.4
Badet, B.5
Polikarpov, I.6
Littlechild, J.A.7
Teplyakov, A.8
-
168
-
-
0030040102
-
Structural studies of Escherichia coli UDP-N-acetylmuramate: L-alanine ligase
-
Jin H, Emanuele JJ Jr., Fairman R, Robertson JG, Hail ME, Ho H-T, Falk PJ Villafranca JJ (1996) Structural studies of Escherichia coli UDP-N-acetylmuramate: l-alanine ligase. Biochemistry 35 : 1423 1431.
-
(1996)
Biochemistry
, vol.35
, pp. 1423-1431
-
-
Jin, H.1
Emanuele Jr., J.J.2
Fairman, R.3
Robertson, J.G.4
Hail, M.E.5
Ho, H.-T.6
Falk, P.J.7
Villafranca, J.J.8
-
169
-
-
0030931977
-
The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase
-
Jolly L, Wu S, van Heijenoort J, de Lencastre H, Mengin-Lecreulx D Tomasz A (1997) The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase. J Bacteriol 179 : 5321 5325.
-
(1997)
J Bacteriol
, vol.179
, pp. 5321-5325
-
-
Jolly, L.1
Wu, S.2
Van Heijenoort, J.3
De Lencastre, H.4
Mengin-Lecreulx, D.5
Tomasz, A.6
-
170
-
-
0033563016
-
Reaction mechanism of phosphoglucosamine mutase from Escherichia coli
-
Jolly L, Ferrari P, Blanot D, van Heijenoort J, Fassy F Mengin-Lecreulx D (1999) Reaction mechanism of phosphoglucosamine mutase from Escherichia coli. Eur J Biochem 262 : 202 210.
-
(1999)
Eur J Biochem
, vol.262
, pp. 202-210
-
-
Jolly, L.1
Ferrari, P.2
Blanot, D.3
Van Heijenoort, J.4
Fassy, F.5
Mengin-Lecreulx, D.6
-
171
-
-
0033953802
-
Autophosphorylation of phosphoglucosamine mutase from Escherichia coli
-
Jolly L, Pompeo F, van Heijenoort J, Fassy F Mengin-Lecreulx D (2000) Autophosphorylation of phosphoglucosamine mutase from Escherichia coli. J Bacteriol 182 : 1280 1285.
-
(2000)
J Bacteriol
, vol.182
, pp. 1280-1285
-
-
Jolly, L.1
Pompeo, F.2
Van Heijenoort, J.3
Fassy, F.4
Mengin-Lecreulx, D.5
-
172
-
-
0037241238
-
Structure-based approaches to cell wall biosynthesis inhibitors
-
Katz AH Caufield CE (2003) Structure-based approaches to cell wall biosynthesis inhibitors. Curr Pharm Design 9 : 857 866.
-
(2003)
Curr Pharm Design
, vol.9
, pp. 857-866
-
-
Katz, A.H.1
Caufield, C.E.2
-
173
-
-
0017080739
-
The mode of action of bacilysin and anticapsin and biochemical properties of bacilysin-resistant mutants
-
Kenig M, Vandamme E Abraham EP (1976) The mode of action of bacilysin and anticapsin and biochemical properties of bacilysin-resistant mutants. J Gen Microbiol 94 : 46 54.
-
(1976)
J Gen Microbiol
, vol.94
, pp. 46-54
-
-
Kenig, M.1
Vandamme, E.2
Abraham, E.P.3
-
175
-
-
0029967416
-
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin
-
Kim DH, Lees WJ, Kempsell KE, Lane WS, Duncan K Walsh CT (1996) Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. Biochemistry 35 : 4923 4928.
-
(1996)
Biochemistry
, vol.35
, pp. 4923-4928
-
-
Kim, D.H.1
Lees, W.J.2
Kempsell, K.E.3
Lane, W.S.4
Duncan, K.5
Walsh, C.T.6
-
176
-
-
34547932250
-
Structural basis for glutamate racamase inhibition
-
Kim K-H, Bong Y-J, Park JK, Shin K-J, Hwang KY Kim EE (2007) Structural basis for glutamate racamase inhibition. J Mol Biol 372 : 434 443.
-
(2007)
J Mol Biol
, vol.372
, pp. 434-443
-
-
Kim, K.-H.1
Bong, Y.-J.2
Park, J.K.3
Shin, K.-J.4
Hwang, K.Y.5
Kim, E.E.6
-
177
-
-
0942301251
-
Evaluation of amino-substitued heterocyclic derivatives as alanine racemase inhibitors
-
Kim MG, Strych U, Krause KL, Benedik MJ Kohn H (2003a) Evaluation of amino-substitued heterocyclic derivatives as alanine racemase inhibitors. Med Chem Res 12 : 130 138.
-
(2003)
Med Chem Res
, vol.12
, pp. 130-138
-
-
Kim, M.G.1
Strych, U.2
Krause, K.L.3
Benedik, M.J.4
Kohn, H.5
-
178
-
-
0345700229
-
N(2)-substituted d,l-cycloserine derivatives: Synthesis and evaluation as alanine racemase inhibitors
-
Kim MG, Strych U, Krause K, Benedik M Kohn H (2003b) N(2)-substituted d,l-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors. J Antibiot (Tokyo) 56 : 160 168.
-
(2003)
J Antibiot (Tokyo)
, vol.56
, pp. 160-168
-
-
Kim, M.G.1
Strych, U.2
Krause, K.3
Benedik, M.4
Kohn, H.5
-
179
-
-
33846218732
-
Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
-
Kim MK, Cho MK, Song HE et al 2007) Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus. Proteins 66 : 751 754.
-
(2007)
Proteins
, vol.66
, pp. 751-754
-
-
Kim, M.K.1
Cho, M.K.2
Song, H.E.3
Al, E.4
-
180
-
-
0034492786
-
Isolation of peptide ligands that inhibit glutamate racemase activity from a random phage display library
-
Kim W-C, Rhee H-I, Park B-K, Suk K-H Cha S-H (2000) Isolation of peptide ligands that inhibit glutamate racemase activity from a random phage display library. J Biomol Screen 5 : 435 440.
-
(2000)
J Biomol Screen
, vol.5
, pp. 435-440
-
-
Kim, W.-C.1
Rhee, H.-I.2
Park, B.-K.3
Suk, K.-H.4
Cha, S.-H.5
-
181
-
-
4844224731
-
Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis
-
Kimura K, Tran LS Itoh Y (2004) Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis. Microbiology 150 : 2911 2920.
-
(2004)
Microbiology
, vol.150
, pp. 2911-2920
-
-
Kimura, K.1
Tran, L.S.2
Itoh, Y.3
-
183
-
-
0031032662
-
ATP binding proteins with different folds share a common ATP-binding structural motif
-
Kobayashi N Go N (1997) ATP binding proteins with different folds share a common ATP-binding structural motif. Nat Struct Biol 4 : 6 7.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 6-7
-
-
Kobayashi, N.1
Go, N.2
-
184
-
-
0015917626
-
New antibacterial agent via photofluorination of a bacterial cell wall constituent
-
Kollonitsch J, Barash L, Kahan FM Kropp H (1973) New antibacterial agent via photofluorination of a bacterial cell wall constituent. Nature 243 : 346 347.
-
(1973)
Nature
, vol.243
, pp. 346-347
-
-
Kollonitsch, J.1
Barash, L.2
Kahan, F.M.3
Kropp, H.4
-
185
-
-
4344564753
-
The gate controlling cell wall synthesis in Staphylococcus aureus
-
Komatsuzawa H, Fujiwara T, Nishi H, Yamada S, Ohara M, McCallum N, Berger-Bächi B Sugai M (2004) The gate controlling cell wall synthesis in Staphylococcus aureus. Mol Microbiol 53 : 1221 1231.
-
(2004)
Mol Microbiol
, vol.53
, pp. 1221-1231
-
-
Komatsuzawa, H.1
Fujiwara, T.2
Nishi, H.3
Yamada, S.4
Ohara, M.5
McCallum, N.6
Berger-Bächi, B.7
Sugai, M.8
-
186
-
-
34047271769
-
Comparison of 3D-QSAR methods using a novel class of MurF inhibitors
-
Kong D-X, Zhu W-L, Wu D-L, Shen X Jiang H-L (2007) Comparison of 3D-QSAR methods using a novel class of MurF inhibitors. J Theor Comput Chem 6 : 63 80.
-
(2007)
J Theor Comput Chem
, vol.6
, pp. 63-80
-
-
Kong, D.-X.1
Zhu, W.-L.2
Wu, D.-L.3
Shen, X.4
Jiang, H.-L.5
-
188
-
-
8544228354
-
Quantitative structure-activity relationships of Streptococcus pneumoniae MurD transition-state inhibitors
-
Kotnik M, Oblak M, Humljan J, Gobec S, Urleb U Šolmajer T (2004) Quantitative structure-activity relationships of Streptococcus pneumoniae MurD transition-state inhibitors. QSAR Comb Sci 23 : 399 405.
-
(2004)
QSAR Comb Sci
, vol.23
, pp. 399-405
-
-
Kotnik, M.1
Oblak, M.2
Humljan, J.3
Gobec, S.4
Urleb, U.5
Šolmajer, T.6
-
189
-
-
34548258863
-
Development of novel inhibitors targeting intracellular steps of peptidoglycan biosynthesis
-
Kotnik M, Štefanič Anderluh P Preželj A (2007a) Development of novel inhibitors targeting intracellular steps of peptidoglycan biosynthesis. Curr Pharm Des 13 : 2283 2309.
-
(2007)
Curr Pharm des
, vol.13
, pp. 2283-2309
-
-
Kotnik, M.1
Štefanič Anderluh, P.2
Preželj, A.3
-
190
-
-
34249703449
-
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase
-
Kotnik M, Humljan J, Contreras-Martel C et al 2007b) Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase. J Mol Biol 370 : 107 115.
-
(2007)
J Mol Biol
, vol.370
, pp. 107-115
-
-
Kotnik, M.1
Humljan, J.2
Contreras-Martel, C.3
Al, E.4
-
191
-
-
33847775590
-
Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl)
-
Kovač A, Majce V, Lenaršič R, Bombek S, Bostock JM, Chopra I, Polanc S Gobec S (2007) Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl). Bioorg Med Chem Lett 17 : 2047 2054.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2047-2054
-
-
Kovač, A.1
Majce, V.2
Lenaršič, R.3
Bombek, S.4
Bostock, J.M.5
Chopra, I.6
Polanc, S.7
Gobec, S.8
-
193
-
-
33845902543
-
Chemoenzymatic synthesis of Park's nucleotide: Toward the development of high-throughput screening of MraY inhibitors
-
Kurosu M, Mahapatra S, Narayanasamy P Crick DC (2007) Chemoenzymatic synthesis of Park's nucleotide: toward the development of high-throughput screening of MraY inhibitors. Tetrahedron Lett 48 : 799 803.
-
(2007)
Tetrahedron Lett
, vol.48
, pp. 799-803
-
-
Kurosu, M.1
Mahapatra, S.2
Narayanasamy, P.3
Crick, D.C.4
-
194
-
-
20944432485
-
4-Alkyl and 4,4′-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5- dione derivatives as new inhibitors of bacterial cell wall biosynthesis
-
Kutterer KM, Davis JM, Singh G, Yang Y, Hu W, Severin A, Rasmussen BA, Krishnamurthy G, Failli A Katz AH (2005) 4-Alkyl and 4,4′-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis. Bioorg Med Chem Lett 15 : 2527 2531.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 2527-2531
-
-
Kutterer, K.M.1
Davis, J.M.2
Singh, G.3
Yang, Y.4
Hu, W.5
Severin, A.6
Rasmussen, B.A.7
Krishnamurthy, G.8
Failli, A.9
Katz, A.H.10
-
195
-
-
0034657320
-
Enzymes of vancomycin resistance: The structure of d-alanine-d-lactate ligase of naturally resistant Leuconostoc mesenteroides
-
Kuzin AP, Sun T, Jorczak-Baillass J, Healy VL, Walsh CT Knox JR (2000) Enzymes of vancomycin resistance: the structure of d-alanine-d-lactate ligase of naturally resistant Leuconostoc mesenteroides. Structure 8 : 463 470.
-
(2000)
Structure
, vol.8
, pp. 463-470
-
-
Kuzin, A.P.1
Sun, T.2
Jorczak-Baillass, J.3
Healy, V.L.4
Walsh, C.T.5
Knox, J.R.6
-
196
-
-
39149128036
-
-
Antibiotic cycloalkyltetrahydroquinolone derivatives. US Patent, application number WO2005025556 A2.
-
Labaudiniere RF, Xiang Y, Jalluri RK Arvanites AC (2005) Antibiotic cycloalkyltetrahydroquinolone derivatives. US Patent, application number WO2005025556 A2.
-
(2005)
-
-
Labaudiniere, R.F.1
Xiang, Y.2
Jalluri, R.K.3
Arvanites, A.C.4
-
197
-
-
0018667050
-
Inhibition of d-alanyl-d-alanine ligase in different bacterial species by amino phosphonic acids
-
Lacoste A-M, Poulsen M, Cassaigne A Neuzil E (1979) Inhibition of d-alanyl-d-alanine ligase in different bacterial species by amino phosphonic acids. Curr Microbiol 2 : 113 117.
-
(1979)
Curr Microbiol
, vol.2
, pp. 113-117
-
-
Lacoste, A.-M.1
Poulsen, M.2
Cassaigne, A.3
Neuzil, E.4
-
198
-
-
0025856757
-
Time-dependent inhibition of Streptococcus faecalis d-alanine : dd-alanine ligase byα -aminophosphonamidic acids
-
Lacoste A-M, Chollet-Gravey A-M, Vo Quang L, Vo Quang Y Le Goffic F (1991) Time-dependent inhibition of Streptococcus faecalis d-alanine : d-alanine ligase by α-aminophosphonamidic acids. Eur J Med Chem 26 : 255 260.
-
(1991)
Eur J Med Chem
, vol.26
, pp. 255-260
-
-
Lacoste, A.-M.1
Chollet-Gravey, A.-M.2
Vo Quang, L.3
Vo Quang, Y.4
Le Goffic, F.5
-
199
-
-
33748474606
-
Crystal structure of the apo form of d-alanine : dd-alanine ligase (Ddl) from Thermus caldophilus: A basis for the substrate-induced conformational changes
-
Lee JH, Na Y, Song HE et al 2006a) Crystal structure of the apo form of d-alanine : d-alanine ligase (Ddl) from Thermus caldophilus: a basis for the substrate-induced conformational changes. Proteins 64 : 1078 1082.
-
(2006)
Proteins
, vol.64
, pp. 1078-1082
-
-
Lee, J.H.1
Na, Y.2
Song, H.E.3
Al, E.4
-
200
-
-
33144484886
-
Functional and structural characterization of thermostable d-amino acid aminotransferases from Geobacillus spp
-
Lee SG, Hong SP, Song JJ, Kim SJ, Kwak MS Sung MH (2006b) Functional and structural characterization of thermostable d-amino acid aminotransferases from Geobacillus spp. Appl Environ Microbiol 72 : 1588 1594.
-
(2006)
Appl Environ Microbiol
, vol.72
, pp. 1588-1594
-
-
Lee, S.G.1
Hong, S.P.2
Song, J.J.3
Kim, S.J.4
Kwak, M.S.5
Sung, M.H.6
-
201
-
-
0028894420
-
Analysis of the enol ether transfer catalyzed by UDP-GlcNAc enolpyruvyl transferase using (E)- and (Z)-isomers of phosphoenolbutyrate: Stereochemical, partitioning, and isotope effect studies
-
Lees WJ Walsh CT (1995) Analysis of the enol ether transfer catalyzed by UDP-GlcNAc enolpyruvyl transferase using (E)- and (Z)-isomers of phosphoenolbutyrate: stereochemical, partitioning, and isotope effect studies. J Am Chem Soc 117 : 7329 7337.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 7329-7337
-
-
Lees, W.J.1
Walsh, C.T.2
-
202
-
-
0030042139
-
(E)-Enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB)
-
Lees WJ, Benson TE, Hogle JM Walsh CT (1996) (E)-Enolbutyryl-UDP-N- acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Biochemistry 35 : 1342 1351.
-
(1996)
Biochemistry
, vol.35
, pp. 1342-1351
-
-
Lees, W.J.1
Benson, T.E.2
Hogle, J.M.3
Walsh, C.T.4
-
203
-
-
13444274582
-
The 1.9 Å crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site
-
LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H Krause KL (2005) The 1.9 Å crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry 44 : 1471 1481.
-
(2005)
Biochemistry
, vol.44
, pp. 1471-1481
-
-
Lemagueres, P.1
Im, H.2
Ebalunode, J.3
Strych, U.4
Benedik, M.J.5
Briggs, J.M.6
Kohn, H.7
Krause, K.L.8
-
204
-
-
0026099922
-
Peptides containing 2-aminopimelic acid. Synthesis and study of in vitro effects on bacterial cells
-
Le Roux P, Blanot D, Mengin-Lecreulx D van Heijenoort J (1991) Peptides containing 2-aminopimelic acid. Synthesis and study of in vitro effects on bacterial cells. Int J Peptide Protein Res 37 : 103 111.
-
(1991)
Int J Peptide Protein Res
, vol.37
, pp. 103-111
-
-
Le Roux, P.1
Blanot, D.2
Mengin-Lecreulx, D.3
Van Heijenoort, J.4
-
205
-
-
0027066885
-
Synthesis of new peptide inhibitors of the meso-diaminopimelate-adding enzyme
-
Le Roux P, Auger G, van Heijenoort J Blanot D (1992) Synthesis of new peptide inhibitors of the meso-diaminopimelate-adding enzyme. Eur J Med Chem 27 : 899 907.
-
(1992)
Eur J Med Chem
, vol.27
, pp. 899-907
-
-
Le Roux, P.1
Auger, G.2
Van Heijenoort, J.3
Blanot, D.4
-
206
-
-
0021986925
-
Design, synthesis and testing of transition state analogues of alanine racemase as antibacterials
-
Leung DK, Andrews PR, Craik DJ, Iskander MN Winkler DA (1985) Design, synthesis and testing of transition state analogues of alanine racemase as antibacterials. Australian J Chem 38 : 297 206.
-
(1985)
Australian J Chem
, vol.38
, pp. 297-206
-
-
Leung, D.K.1
Andrews, P.R.2
Craik, D.J.3
Iskander, M.N.4
Winkler, D.A.5
-
207
-
-
10744223112
-
2-Phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis
-
Li Z, Francisco GD, Hu W et al 2003) 2-Phenyl-5,6-dihydro-2H-thieno[3,2- c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis. Bioorg Med Chem Lett 13 : 2591 2594.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 2591-2594
-
-
Li, Z.1
Francisco, G.D.2
Hu, W.3
Al, E.4
-
208
-
-
0025863089
-
Effect of various alanine analogues on the l-alanine-adding enzyme from Escherichia coli
-
Liger D, Blanot D van Heijenoort J (1991) Effect of various alanine analogues on the l-alanine-adding enzyme from Escherichia coli. FEMS Microbiol Lett 80 : 111 116.
-
(1991)
FEMS Microbiol Lett
, vol.80
, pp. 111-116
-
-
Liger, D.1
Blanot, D.2
Van Heijenoort, J.3
-
209
-
-
0029077340
-
Over-production, purification and properties of the uridine-diphosphate- N-acetylmuramate: L-alanine ligase from Escherichia coli
-
Liger D, Masson A, Blanot D, van Heijenoort J Parquet C (1995) Over-production, purification and properties of the uridine-diphosphate-N- acetylmuramate: l-alanine ligase from Escherichia coli. Eur J Biochem 230 : 80 87.
-
(1995)
Eur J Biochem
, vol.230
, pp. 80-87
-
-
Liger, D.1
Masson, A.2
Blanot, D.3
Van Heijenoort, J.4
Parquet, C.5
-
210
-
-
0029760460
-
Study of the overproduced uridine-diphosphate-N-acetylmuramate: L-alanine ligase from Escherichia coli
-
Liger D, Masson A, Blanot D, van Heijenoort J Parquet C (1996) Study of the overproduced uridine-diphosphate-N-acetylmuramate: l-alanine ligase from Escherichia coli. Microb Drug Resist 2 : 25 27.
-
(1996)
Microb Drug Resist
, vol.2
, pp. 25-27
-
-
Liger, D.1
Masson, A.2
Blanot, D.3
Van Heijenoort, J.4
Parquet, C.5
-
211
-
-
0035840941
-
An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl- peptides
-
Liu H, Sadamoto R, Sears PS Wong C-H (2001) An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides. J Am Chem Soc 123 : 9916 9917.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 9916-9917
-
-
Liu, H.1
Sadamoto, R.2
Sears, P.S.3
Wong, C.-H.4
-
212
-
-
33750045457
-
Allosteric inhibition of Staphylococcus aureus d-alanine : dd-alanine ligase revealed by crystallographic studies
-
Liu S, Chang JS, Herberg JT, Horng M-M, Tomich PK, Lin AH Marotti KR (2006) Allosteric inhibition of Staphylococcus aureus d-alanine : d-alanine ligase revealed by crystallographic studies. Proc Natl Acad Sci USA 103 : 15178 15183.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15178-15183
-
-
Liu, S.1
Chang, J.S.2
Herberg, J.T.3
Horng, M.-M.4
Tomich, P.K.5
Lin, A.H.6
Marotti, K.R.7
-
213
-
-
28844504713
-
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
-
Longenecker K, Stamper GF, Hajduk PJ et al 2005) Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure. Protein Sci 14 : 3039 3047.
-
(2005)
Protein Sci
, vol.14
, pp. 3039-3047
-
-
Longenecker, K.1
Stamper, G.F.2
Hajduk, P.J.3
Al, E.4
-
214
-
-
0031777012
-
Molecular cloning and DNA sequencing of the Staphylococcus aureus UDP-N-acetylmuramyl tripeptide synthetase (murE) gene, essential for the optimal expression of methicillin resistance
-
Ludovice AM, Wu SW de Lencastre H (1998) Molecular cloning and DNA sequencing of the Staphylococcus aureus UDP-N-acetylmuramyl tripeptide synthetase (murE) gene, essential for the optimal expression of methicillin resistance. Microb Drug Resist 4 : 85 90.
-
(1998)
Microb Drug Resist
, vol.4
, pp. 85-90
-
-
Ludovice, A.M.1
Wu, S.W.2
De Lencastre, H.3
-
215
-
-
34250356440
-
Exploitation of structural and regulatory diversity in glutamate racemases
-
Lundqvist T, Fisher SL, Kern G, Folmer RH, Xue Y, Newton DT, Keating TA, Alm RA de Jonge BL (2007) Exploitation of structural and regulatory diversity in glutamate racemases. Nature 447 : 817 822.
-
(2007)
Nature
, vol.447
, pp. 817-822
-
-
Lundqvist, T.1
Fisher, S.L.2
Kern, G.3
Folmer, R.H.4
Xue, Y.5
Newton, D.T.6
Keating, T.A.7
Alm, R.A.8
De Jonge, B.L.9
-
216
-
-
0034351486
-
Comparison of the UDP-N-acetylmuramate: L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae
-
Mahapatra S, Crick DC Brennan PJ (2000) Comparison of the UDP-N-acetylmuramate: l-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae. J Bacteriol 182 : 6827 6830.
-
(2000)
J Bacteriol
, vol.182
, pp. 6827-6830
-
-
Mahapatra, S.1
Crick, D.C.2
Brennan, P.J.3
-
217
-
-
33845569858
-
A combined quantum mechanical and molecular mechanical study of the reaction mechanism and α-amino acidity in alanine racemase
-
Major DT Gao J (2006) A combined quantum mechanical and molecular mechanical study of the reaction mechanism and α-amino acidity in alanine racemase. J Am Chem Soc 128 : 16345 16357.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 16345-16357
-
-
Major, D.T.1
Gao, J.2
-
218
-
-
0035833985
-
Biochemical characterization of a phosphinate inhibitor of Escherichia coli MurC
-
Marmor S, Petersen CP, Reck F, Yang W, Gao N Fisher SL (2001) Biochemical characterization of a phosphinate inhibitor of Escherichia coli MurC. Biochemistry 40 : 12207 12214.
-
(2001)
Biochemistry
, vol.40
, pp. 12207-12214
-
-
Marmor, S.1
Petersen, C.P.2
Reck, F.3
Yang, W.4
Gao, N.5
Fisher, S.L.6
-
219
-
-
0026803196
-
Cloning and sequencing of Escherichia coli murZ and purification of its product, a UDP-N-acetylglucosamine enolpyruvyl transferase
-
Marquardt JL, Siegele DA, Kolter R Walsh CT (1992) Cloning and sequencing of Escherichia coli murZ and purification of its product, a UDP-N-acetylglucosamine enolpyruvyl transferase. J Bacteriol 174 : 5748 5752.
-
(1992)
J Bacteriol
, vol.174
, pp. 5748-5752
-
-
Marquardt, J.L.1
Siegele, D.A.2
Kolter, R.3
Walsh, C.T.4
-
220
-
-
0001731704
-
Isolation and structural elucidation of a tetrahedral intermediate in the UDP-N-acetylglucosamine enolpyruvoyl transferase enzymatic pathway
-
Marquardt JL, Brown ED, Walsh CT Anderson KS (1993) Isolation and structural elucidation of a tetrahedral intermediate in the UDP-N- acetylglucosamine enolpyruvoyl transferase enzymatic pathway. J Am Chem Soc 115 : 10398 10399.
-
(1993)
J Am Chem Soc
, vol.115
, pp. 10398-10399
-
-
Marquardt, J.L.1
Brown, E.D.2
Walsh, C.T.3
Anderson, K.S.4
-
221
-
-
0028070055
-
Kinetics, stoichiometry, and identification of the reactive thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin
-
Marquardt JL, Brown ED, Lane WS, Haley TM, Ichikawa Y, Wong CH Walsh CT (1994) Kinetics, stoichiometry, and identification of the reactive thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin. Biochemistry 33 : 10646 10651.
-
(1994)
Biochemistry
, vol.33
, pp. 10646-10651
-
-
Marquardt, J.L.1
Brown, E.D.2
Lane, W.S.3
Haley, T.M.4
Ichikawa, Y.5
Wong, C.H.6
Walsh, C.T.7
-
222
-
-
34447126347
-
Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans and catalytic reaction mechanism
-
Maruyama D, Nishitani Y, Nonaka T, Kita A, Fukami TA, Mio T, Yamada-Okabe H, Yamada-Okabe T Miki K (2007) Crystal structure of uridine-diphospho-N- acetylglucosamine pyrophosphorylase from Candida albicans and catalytic reaction mechanism. J Biol Chem 282 : 17221 17230.
-
(2007)
J Biol Chem
, vol.282
, pp. 17221-17230
-
-
Maruyama, D.1
Nishitani, Y.2
Nonaka, T.3
Kita, A.4
Fukami, T.A.5
Mio, T.6
Yamada-Okabe, H.7
Yamada-Okabe, T.8
Miki, K.9
-
223
-
-
34547557316
-
Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design
-
May M, Mehboob S, Mulhearn DC, Wang Z, Yu H, Thatcher GR, Santarsiero BD, Johnson ME Mesecar AD (2007) Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design. J Mol Biol 371 : 1219 1237.
-
(2007)
J Mol Biol
, vol.371
, pp. 1219-1237
-
-
May, M.1
Mehboob, S.2
Mulhearn, D.C.3
Wang, Z.4
Yu, H.5
Thatcher, G.R.6
Santarsiero, B.D.7
Johnson, M.E.8
Mesecar, A.D.9
-
224
-
-
21244447071
-
Characterization of Chlamydia MurC-Ddl, a fusion protein exhibiting d-alanyl-d-alanine ligase activity involved in peptidoglycan synthesis and d-cycloserine sensitivity
-
McCoy AJ Maurelli AT (2005) Characterization of Chlamydia MurC-Ddl, a fusion protein exhibiting d-alanyl-d-alanine ligase activity involved in peptidoglycan synthesis and d-cycloserine sensitivity. Mol Microbiol 57 : 41 52.
-
(2005)
Mol Microbiol
, vol.57
, pp. 41-52
-
-
McCoy, A.J.1
Maurelli, A.T.2
-
225
-
-
0037315109
-
In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance
-
McCoy AJ, Sandlin RC Maurelli AT (2003) In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance. J Bacteriol 185 : 1218 1228.
-
(2003)
J Bacteriol
, vol.185
, pp. 1218-1228
-
-
McCoy, A.J.1
Sandlin, R.C.2
Maurelli, A.T.3
-
226
-
-
0025316922
-
Rotational resonance determination of the structure of an enzyme-inhibitor complex: Phosphorylation of an (aminoalkyl)phosphinate inhibitor of d-alanyl-d-alanine ligase by ATP
-
McDermott AE, Creuzet F, Griffin RG, Zawadzke LE, Ye Q-Z Walsh CT (1990) Rotational resonance determination of the structure of an enzyme-inhibitor complex: phosphorylation of an (aminoalkyl)phosphinate inhibitor of d-alanyl-d-alanine ligase by ATP. Biochemistry 29 : 5767 5775.
-
(1990)
Biochemistry
, vol.29
, pp. 5767-5775
-
-
McDermott, A.E.1
Creuzet, F.2
Griffin, R.G.3
Zawadzke, L.E.4
Ye, Q.-Z.5
Walsh, C.T.6
-
227
-
-
0027434077
-
Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli
-
Mengin-Lecreulx D van Heijenoort J (1993) Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli. J Bacteriol 175 : 6150 6157.
-
(1993)
J Bacteriol
, vol.175
, pp. 6150-6157
-
-
Mengin-Lecreulx, D.1
Van Heijenoort, J.2
-
228
-
-
0027938707
-
Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: Characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis
-
Mengin-Lecreulx D van Heijenoort J (1994) Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis. J Bacteriol 176 : 5788 5795.
-
(1994)
J Bacteriol
, vol.176
, pp. 5788-5795
-
-
Mengin-Lecreulx, D.1
Van Heijenoort, J.2
-
229
-
-
0030032719
-
Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli
-
Mengin-Lecreulx D van Heijenoort J (1996) Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli. J Biol Chem 271 : 32 39.
-
(1996)
J Biol Chem
, vol.271
, pp. 32-39
-
-
Mengin-Lecreulx, D.1
Van Heijenoort, J.2
-
230
-
-
0020458828
-
Cytoplasmic steps of peptidoglycan synthesis in Escherichia coli
-
Mengin-Lecreulx D, Flouret B van Heijenoort J (1982) Cytoplasmic steps of peptidoglycan synthesis in Escherichia coli. J Bacteriol 151 : 1109 1117.
-
(1982)
J Bacteriol
, vol.151
, pp. 1109-1117
-
-
Mengin-Lecreulx, D.1
Flouret, B.2
Van Heijenoort, J.3
-
231
-
-
0023949796
-
Incorporation of ll-diaminopimelic acid into peptidoglycan of Escherichia coli mutants lacking diaminopimelate epimerase encoded by dapF
-
Mengin-Lecreulx D, Michaud C, Richaud C, Blanot D van Heijenoort J (1988) Incorporation of ll-diaminopimelic acid into peptidoglycan of Escherichia coli mutants lacking diaminopimelate epimerase encoded by dapF. J Bacteriol 170 : 2031 2039.
-
(1988)
J Bacteriol
, vol.170
, pp. 2031-2039
-
-
Mengin-Lecreulx, D.1
Michaud, C.2
Richaud, C.3
Blanot, D.4
Van Heijenoort, J.5
-
232
-
-
0024416945
-
Organization of the murE-murG region of Escherichia coli: Identification of the murD gene encoding the d-glutamic-acid-adding enzyme
-
Mengin-Lecreulx D, Parquet C, Desviat LR, Plá J, Flouret B, Ayala JA van Heijenoort J (1989) Organization of the murE-murG region of Escherichia coli: identification of the murD gene encoding the d-glutamic-acid-adding enzyme. J Bacteriol 171 : 6126 6134.
-
(1989)
J Bacteriol
, vol.171
, pp. 6126-6134
-
-
Mengin-Lecreulx, D.1
Parquet, C.2
Desviat, L.R.3
Plá, J.4
Flouret, B.5
Ayala, J.A.6
Van Heijenoort, J.7
-
233
-
-
0028361885
-
Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli
-
Mengin-Lecreulx D, Blanot D van Heijenoort J (1994) Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli. J Bacteriol 176 : 4321 4327.
-
(1994)
J Bacteriol
, vol.176
, pp. 4321-4327
-
-
Mengin-Lecreulx, D.1
Blanot, D.2
Van Heijenoort, J.3
-
234
-
-
0029787789
-
Identification of the mpl gene encoding UDP-N-acetylmuramate: L-alanyl-γ-d-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan
-
Mengin-Lecreulx D, van Heijenoort J Park JT (1996) Identification of the mpl gene encoding UDP-N-acetylmuramate: l-alanyl-γ-d-glutamyl-meso- diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan. J Bacteriol 178 : 5347 5352.
-
(1996)
J Bacteriol
, vol.178
, pp. 5347-5352
-
-
Mengin-Lecreulx, D.1
Van Heijenoort, J.2
Park, J.T.3
-
236
-
-
0032823023
-
Expression of the Staphylococcus aureus UDP-N-acetylmuramoyl-l-alanyl-d- glutamate: L-lysine ligase in Escherichia coli and effects on peptidoglycan biosynthesis and cell growth
-
Mengin-Lecreulx D, Falla T, Blanot D, van Heijenoort J, Adams DJ Chopra I (1999) Expression of the Staphylococcus aureus UDP-N-acetylmuramoyl-l-alanyl-d- glutamate: l-lysine ligase in Escherichia coli and effects on peptidoglycan biosynthesis and cell growth. J Bacteriol 181 : 5909 5914.
-
(1999)
J Bacteriol
, vol.181
, pp. 5909-5914
-
-
Mengin-Lecreulx, D.1
Falla, T.2
Blanot, D.3
Van Heijenoort, J.4
Adams, D.J.5
Chopra, I.6
-
237
-
-
0023643132
-
Partial purification and specificity studies of the d-glutamate-adding and d-alanyl-d-alanine-adding enzymes from Escherichia coli K12
-
Michaud C, Blanot D, Flouret B van Heijenoort J (1987) Partial purification and specificity studies of the d-glutamate-adding and d-alanyl-d-alanine-adding enzymes from Escherichia coli K12. Eur J Biochem 166 : 631 637.
-
(1987)
Eur J Biochem
, vol.166
, pp. 631-637
-
-
Michaud, C.1
Blanot, D.2
Flouret, B.3
Van Heijenoort, J.4
-
238
-
-
0025688726
-
Over-production, purification and properties of the uridine-diphosphate- N-acetylmuramoyl-l-alanine-d-glutamate: Meso-2,6-diaminopimelate ligase from Escherichia coli
-
Michaud C, Mengin-Lecreulx D, van Heijenoort J Blanot D (1990) Over-production, purification and properties of the uridine-diphosphate-N- acetylmuramoyl-l-alanine-d-glutamate: meso-2,6-diaminopimelate ligase from Escherichia coli. Eur J Biochem 194 : 853 861.
-
(1990)
Eur J Biochem
, vol.194
, pp. 853-861
-
-
Michaud, C.1
Mengin-Lecreulx, D.2
Van Heijenoort, J.3
Blanot, D.4
-
239
-
-
32544436403
-
Enzymes of UDP-GlcNAc biosynthesis in yeast
-
Milewski S, Gabriel I Olchowy J (2006) Enzymes of UDP-GlcNAc biosynthesis in yeast. Yeast 23 : 1 14.
-
(2006)
Yeast
, vol.23
, pp. 1-14
-
-
Milewski, S.1
Gabriel, I.2
Olchowy, J.3
-
241
-
-
0032486252
-
The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases: Gene cloning, protein expression, and catalytic mechanism
-
Mio T, Yabe T, Arisawa M Yamada-Okabe H (1998) The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases: gene cloning, protein expression, and catalytic mechanism. J Biol Chem 273 : 14392 14397.
-
(1998)
J Biol Chem
, vol.273
, pp. 14392-14397
-
-
Mio, T.1
Yabe, T.2
Arisawa, M.3
Yamada-Okabe, H.4
-
242
-
-
0032898932
-
Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis
-
Mio T, Yamada-Okabe T, Arisawa M Yamada-Okabe H (1999) Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis. J Biol Chem 274 : 424 429.
-
(1999)
J Biol Chem
, vol.274
, pp. 424-429
-
-
Mio, T.1
Yamada-Okabe, T.2
Arisawa, M.3
Yamada-Okabe, H.4
-
243
-
-
0015421372
-
Cell wall peptidoglycan mutants of Escherichia coli K-12: Existence of two clusters of genes, mra and mrb, for cell wall peptidoglycan biosynthesis
-
Miyakawa T, Matsuzawa H, Matsuhashi M Sugino Y (1972) Cell wall peptidoglycan mutants of Escherichia coli K-12: existence of two clusters of genes, mra and mrb, for cell wall peptidoglycan biosynthesis. J Bacteriol 112 : 950 958.
-
(1972)
J Bacteriol
, vol.112
, pp. 950-958
-
-
Miyakawa, T.1
Matsuzawa, H.2
Matsuhashi, M.3
Sugino, Y.4
-
244
-
-
14844347076
-
UDP-N-acetylmuramic acid (UDP-MurNAc) is a potent inhibitor of MurA (enolpyruvyl-UDP-GlcNAc synthase)
-
Mizyed S, Oddone A, Byczynski B, Hughes DW Berti PJ (2005) UDP-N-acetylmuramic acid (UDP-MurNAc) is a potent inhibitor of MurA (enolpyruvyl-UDP-GlcNAc synthase). Biochemistry 44 : 4011 4017.
-
(2005)
Biochemistry
, vol.44
, pp. 4011-4017
-
-
Mizyed, S.1
Oddone, A.2
Byczynski, B.3
Hughes, D.W.4
Berti, P.J.5
-
245
-
-
3342957245
-
Multiple substrate binding states and chiral recognition in cofactor-independent glutamate racemase: A molecular dynamics study
-
Möbitz H Bruice TC (2004) Multiple substrate binding states and chiral recognition in cofactor-independent glutamate racemase: a molecular dynamics study. Biochemistry 43 : 9685 9694.
-
(2004)
Biochemistry
, vol.43
, pp. 9685-9694
-
-
Möbitz, H.1
Bruice, T.C.2
-
246
-
-
39149121257
-
-
Heterocyclic compounds and uses thereof as d-alanyl-d-alanine ligase inhibitors. US Patent, application number PCT/US02/20567, WO 03/001887 A2.
-
Moe ST, Ala PJ Perola E (2003) Heterocyclic compounds and uses thereof as d-alanyl-d-alanine ligase inhibitors. US Patent, application number PCT/US02/20567, WO 03/001887 A2.
-
(2003)
-
-
Moe, S.T.1
Ala, P.J.2
Perola, E.3
-
247
-
-
0038492584
-
Crystal structures of active fully assembled substrate- and product-bound complexes of UDP-N-acetylmuramic acid: L-alanine ligase (MurC) from Haemophilus influenzae
-
Mol CD, Brooun A, Dougan DR, Hilgers MT, Tari LW, Wijnands RA, Knuth MW, McRee DE Swanson RW (2003) Crystal structures of active fully assembled substrate- and product-bound complexes of UDP-N-acetylmuramic acid: l-alanine ligase (MurC) from Haemophilus influenzae. J Bacteriol 185 : 4152 4162.
-
(2003)
J Bacteriol
, vol.185
, pp. 4152-4162
-
-
Mol, C.D.1
Brooun, A.2
Dougan, D.R.3
Hilgers, M.T.4
Tari, L.W.5
Wijnands, R.A.6
Knuth, M.W.7
McRee, D.E.8
Swanson, R.W.9
-
248
-
-
33751094053
-
A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: The first committed step in peptidoglycan biosynthesis
-
Molina-López J, Sanschagrin F Levesque RC (2006) A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: the first committed step in peptidoglycan biosynthesis. Peptides 27 : 3115 3121.
-
(2006)
Peptides
, vol.27
, pp. 3115-3121
-
-
Molina-López, J.1
Sanschagrin, F.2
Levesque, R.C.3
-
249
-
-
0033574155
-
Structure of a Michaelis complex analogue: Propionate binds in the substrate carboxylate site of alanine racemase
-
Morollo AA, Petsko GA Ringe D (1999) Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase. Biochemistry 38 : 3293 3301.
-
(1999)
Biochemistry
, vol.38
, pp. 3293-3301
-
-
Morollo, A.A.1
Petsko, G.A.2
Ringe, D.3
-
250
-
-
0027205450
-
Why is Chlamydia sensitive to penicillin in the absence of peptidoglycan?
-
Moulder JW (1993) Why is Chlamydia sensitive to penicillin in the absence of peptidoglycan? Infect Agents Dis 2 : 87 99.
-
(1993)
Infect Agents Dis
, vol.2
, pp. 87-99
-
-
Moulder, J.W.1
-
251
-
-
0025353241
-
Kinetic evidence for the formation of d-alanyl phosphate in the mechanism of d-alanyl-d-alanine ligase
-
Mullins LS, Zawadzke LE, Walsh CT Raushel FM (1990) Kinetic evidence for the formation of d-alanyl phosphate in the mechanism of d-alanyl-d-alanine ligase. J Biol Chem 265 : 8993 8998.
-
(1990)
J Biol Chem
, vol.265
, pp. 8993-8998
-
-
Mullins, L.S.1
Zawadzke, L.E.2
Walsh, C.T.3
Raushel, F.M.4
-
252
-
-
0037499658
-
A structure-based design approach for the identification of novel inhibitors: Application to an alanine racemase
-
Mustata GI Briggs JM (2002) A structure-based design approach for the identification of novel inhibitors: application to an alanine racemase. J Comput Aided Mol Des 16 : 935 953.
-
(2002)
J Comput Aided Mol des
, vol.16
, pp. 935-953
-
-
Mustata, G.I.1
Briggs, J.M.2
-
253
-
-
0000506164
-
Cloning and expression in Escherichia coli of the glutamate racemase gene from Pediococcus pentosaceus
-
Nakajima N, Tanizawa K, Tanaka H Soda K (1986) Cloning and expression in Escherichia coli of the glutamate racemase gene from Pediococcus pentosaceus. Agric Biol Chem 50 : 2823 2830.
-
(1986)
Agric Biol Chem
, vol.50
, pp. 2823-2830
-
-
Nakajima, N.1
Tanizawa, K.2
Tanaka, H.3
Soda, K.4
-
254
-
-
34250653297
-
Synthesis of substrates and biochemical probes for study of the peptidoglycan biosynthetic pathway
-
Narayan RS VanNieuwenhze MS (2007) Synthesis of substrates and biochemical probes for study of the peptidoglycan biosynthetic pathway. Eur J Org Chem 1399 1414.
-
(2007)
Eur J Org Chem
, pp. 1399-1414
-
-
Narayan, R.S.1
Vannieuwenhze, M.S.2
-
255
-
-
39149128831
-
-
Structure-based drug design methods for identifying d-Ala-d-Ala ligase inhibitors as antibacterial drugs. US Patent, application number PCT/US02/20465, WO 03/002063 A2.
-
Navia MA, Ala PJ, Griffith JP, Ali JA, Faerman CH, Moe ST, Magee AS, Connelly PR Perola E (2003) Structure-based drug design methods for identifying d-Ala-d-Ala ligase inhibitors as antibacterial drugs. US Patent, application number PCT/US02/20465, WO 03/002063 A2.
-
(2003)
-
-
Navia, M.A.1
Ala, P.J.2
Griffith, J.P.3
Ali, J.A.4
Faerman, C.H.5
Moe, S.T.6
Magee, A.S.7
Connelly, P.R.8
Perola, E.9
-
256
-
-
0001208835
-
The enzymatic synthesis of d-alanyl-dalanine. I. Purification and properties of d-alanyl-d-alanine synthetase
-
Neuhaus FC (1962a) The enzymatic synthesis of d-alanyl-dalanine. I. Purification and properties of d-alanyl-d-alanine synthetase. J Biol Chem 237 : 778 786.
-
(1962)
J Biol Chem
, vol.237
, pp. 778-786
-
-
Neuhaus, F.C.1
-
257
-
-
0002767481
-
The enzymatic synthesis of d-alanyl-d-alanine. II. Kinetic studies on d-alanyl-d-alanine synthetase
-
Neuhaus FC (1962b) The enzymatic synthesis of d-alanyl-d-alanine. II. Kinetic studies on d-alanyl-d-alanine synthetase. J Biol Chem 237 : 3128 3135.
-
(1962)
J Biol Chem
, vol.237
, pp. 3128-3135
-
-
Neuhaus, F.C.1
-
258
-
-
0000356412
-
The enzymatic synthesis of d-alanyl-d-alanine. III. on the inhibition of d-alanyl-d-alanine synthetase by the antibiotic d-cycloserine
-
Neuhaus FC Lynch JL (1964) The enzymatic synthesis of d-alanyl-d-alanine. III. On the inhibition of d-alanyl-d-alanine synthetase by the antibiotic d-cycloserine. Biochemistry 3 : 471 480.
-
(1964)
Biochemistry
, vol.3
, pp. 471-480
-
-
Neuhaus, F.C.1
Lynch, J.L.2
-
259
-
-
0002753892
-
Enzymatic synthesis of analogs of the cell-wall precursor. I. Kinetics and specificity of uridine diphospho-N-acetylmuramyl-l-alanyl-d-glutamyl-l- lysine :d-alanyl-d-alanine ligase (adenosine diphosphate) from Streptococcus faecalis R
-
Neuhaus FC Struve WG (1965) Enzymatic synthesis of analogs of the cell-wall precursor. I. Kinetics and specificity of uridine diphospho-N- acetylmuramyl-l-alanyl-d-glutamyl-l-lysine :d-alanyl-d-alanine ligase (adenosine diphosphate) from Streptococcus faecalis R. Biochemistry 4 : 120 131.
-
(1965)
Biochemistry
, vol.4
, pp. 120-131
-
-
Neuhaus, F.C.1
Struve, W.G.2
-
260
-
-
0019766646
-
Inhibition of cell wall biosynthesis by analogues of alanine
-
Neuhaus FC Hammes WP (1981) Inhibition of cell wall biosynthesis by analogues of alanine. Pharmac Ther 14 : 265 319.
-
(1981)
Pharmac Ther
, vol.14
, pp. 265-319
-
-
Neuhaus, F.C.1
Hammes, W.P.2
-
261
-
-
33644986330
-
Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus
-
Nishida S, Kurokawa K, Matsuo M, Sakamoto K, Ueno K, Kita K Sekimizu K (2006) Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus. J Biol Chem 281 : 1714 1724.
-
(2006)
J Biol Chem
, vol.281
, pp. 1714-1724
-
-
Nishida, S.1
Kurokawa, K.2
Matsuo, M.3
Sakamoto, K.4
Ueno, K.5
Kita, K.6
Sekimizu, K.7
-
262
-
-
33745837411
-
Crystal structures of N-acetylglucosamine-phosphate mutase, a member of the a-d-phosphohexomutase superfamily, and its substrate and product complexes
-
Nishitani Y, Maruyama D, Nonaka T, Kita A, Fukami TA, Mio T, Yamada-Okabe H, Yamada-Okabe T Miki K (2006) Crystal structures of N-acetylglucosamine- phosphate mutase, a member of the a-d-phosphohexomutase superfamily, and its substrate and product complexes. J Biol Chem 281 : 19740 19747.
-
(2006)
J Biol Chem
, vol.281
, pp. 19740-19747
-
-
Nishitani, Y.1
Maruyama, D.2
Nonaka, T.3
Kita, A.4
Fukami, T.A.5
Mio, T.6
Yamada-Okabe, H.7
Yamada-Okabe, T.8
Miki, K.9
-
263
-
-
0032562803
-
Site-directed mutagenesis and chemical modification of the two cysteine residues of the UDP-N-acetylmuramoyl: L-alanine ligase of Escherichia coli
-
Nosal F, Masson A, Legrand R, Blanot D, Schoot B, van Heijenoort J Parquet C (1998) Site-directed mutagenesis and chemical modification of the two cysteine residues of the UDP-N-acetylmuramoyl: l-alanine ligase of Escherichia coli. FEBS Lett 426 : 309 313.
-
(1998)
FEBS Lett
, vol.426
, pp. 309-313
-
-
Nosal, F.1
Masson, A.2
Legrand, R.3
Blanot, D.4
Schoot, B.5
Van Heijenoort, J.6
Parquet, C.7
-
264
-
-
0028117649
-
Crystallization and preliminary X-ray analysis of the two domains of glucosamine-6-phosphate synthase from Escherichia coli
-
Obmolova G, Badet-Denisot MA, Badet B Teplyakov A (1994) Crystallization and preliminary X-ray analysis of the two domains of glucosamine-6-phosphate synthase from Escherichia coli. J Mol Biol 242 : 703 705.
-
(1994)
J Mol Biol
, vol.242
, pp. 703-705
-
-
Obmolova, G.1
Badet-Denisot, M.A.2
Badet, B.3
Teplyakov, A.4
-
265
-
-
33748792538
-
Expression of alr gene from Corynebacterium glutamicum ATCC
-
13032 in Escherichia coli and molecular characterization of the recombinant alanine racemase.
-
Oikawa T, Tauch A, Schaffer S Fujioka T (2006) Expression of alr gene from Corynebacterium glutamicum ATCC 13032 in Escherichia coli and molecular characterization of the recombinant alanine racemase. J Biotechnol 125 : 503 512.
-
(2006)
J Biotechnol
, vol.125
, pp. 503-512
-
-
Oikawa, T.1
Tauch, A.2
Schaffer, S.3
Fujioka, T.4
-
266
-
-
0035916240
-
Structure of the Escherichia coli GlmU pyrophosphorylase and acetyltransferase active sites
-
Olsen LR Roderick SL (2001) Structure of the Escherichia coli GlmU pyrophosphorylase and acetyltransferase active sites. Biochemistry 40 : 1913 1921.
-
(2001)
Biochemistry
, vol.40
, pp. 1913-1921
-
-
Olsen, L.R.1
Roderick, S.L.2
-
267
-
-
34249826647
-
Structure of the E. coli bifunctional GlmU acetyltransferase active site with substrates and products
-
Olsen LR, Vetting MW Roderick SL (2007) Structure of the E. coli bifunctional GlmU acetyltransferase active site with substrates and products. Protein Sci 16 : 1230 1235.
-
(2007)
Protein Sci
, vol.16
, pp. 1230-1235
-
-
Olsen, L.R.1
Vetting, M.W.2
Roderick, S.L.3
-
268
-
-
33744983912
-
Selection of peptide inhibitors against the Pseudomonas aeruginosa MurD cell wall enzyme
-
Paradis-Bleau C, Beaumont M, Boudreault L, Lloyd A, Sanschagrin F, Bugg TD Levesque RC (2006) Selection of peptide inhibitors against the Pseudomonas aeruginosa MurD cell wall enzyme. Peptides 27 : 1693 1700.
-
(2006)
Peptides
, vol.27
, pp. 1693-1700
-
-
Paradis-Bleau, C.1
Beaumont, M.2
Boudreault, L.3
Lloyd, A.4
Sanschagrin, F.5
Bugg, T.D.6
Levesque, R.C.7
-
269
-
-
84873753419
-
Uridine 5′-pyrophosphate derivatives. I. Isolation from Staphylococcus aureus
-
Park JT (1952) Uridine 5′-pyrophosphate derivatives. I. Isolation from Staphylococcus aureus. J Biol Chem 194 : 877 884.
-
(1952)
J Biol Chem
, vol.194
, pp. 877-884
-
-
Park, J.T.1
-
270
-
-
0023689077
-
Phosphinic acid inhibitors of d-alanyl-d-alanine ligase
-
Parsons WH, Patchett AA, Bull HG et al 1988) Phosphinic acid inhibitors of d-alanyl-d-alanine ligase. J Med Chem 31 : 1772 1778.
-
(1988)
J Med Chem
, vol.31
, pp. 1772-1778
-
-
Parsons, W.H.1
Patchett, A.A.2
Bull, H.G.3
Al, E.4
-
271
-
-
0023838904
-
Antibacterial activities of fluorovinyl- and chlorovinylglycine and several derived dipeptides
-
Patchett AA, Taub D, Weissberger B, Valiant ME, Gadebusch H, Thornberry NA Bull HG (1988) Antibacterial activities of fluorovinyl- and chlorovinylglycine and several derived dipeptides. Antimicrob Agents Chemother 32 : 319 323.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 319-323
-
-
Patchett, A.A.1
Taub, D.2
Weissberger, B.3
Valiant, M.E.4
Gadebusch, H.5
Thornberry, N.A.6
Bull, H.G.7
-
272
-
-
0001855145
-
Diaminopimelate and lysine
-
Herrmann, K.L. Somerville, R.L., eds), pp. Addison-Wesley Publishing Co., Reading, MA.
-
Patte J-C (1983) Diaminopimelate and lysine. Amino Acids: Biosynthesis and Genetic Regulation (Herrmann KL Somerville RL, eds), pp. 213 228. Addison-Wesley Publishing Co., Reading, MA.
-
(1983)
Amino Acids: Biosynthesis and Genetic Regulation
, pp. 213-228
-
-
Patte, J.-C.1
-
273
-
-
0032492728
-
Crystallographic study of steps along the reaction pathway of d-amino acid aminotransferase
-
Peisach D, Chipman DM, Van Ophem PW, Manning JM Ringe D (1998) Crystallographic study of steps along the reaction pathway of d-amino acid aminotransferase. Biochemistry 37 : 4958 4967.
-
(1998)
Biochemistry
, vol.37
, pp. 4958-4967
-
-
Peisach, D.1
Chipman, D.M.2
Van Ophem, P.W.3
Manning, J.M.4
Ringe, D.5
-
274
-
-
0035844169
-
The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase
-
Peneff C, Mengin-Lecreulx D Bourne Y (2001a) The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase. J Biol Chem 276 : 16328 16334.
-
(2001)
J Biol Chem
, vol.276
, pp. 16328-16334
-
-
Peneff, C.1
Mengin-Lecreulx, D.2
Bourne, Y.3
-
275
-
-
17944368066
-
Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: Role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture
-
Peneff C, Ferrari P, Charrier V, Taburet Y, Monnier C, Zamboni V, Winter J, Harnois M, Fassy F Bourne Y (2001b) Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture. EMBO J 20 : 6191 6202.
-
(2001)
EMBO J
, vol.20
, pp. 6191-6202
-
-
Peneff, C.1
Ferrari, P.2
Charrier, V.3
Taburet, Y.4
Monnier, C.5
Zamboni, V.6
Winter, J.7
Harnois, M.8
Fassy, F.9
Bourne, Y.10
-
276
-
-
34249904963
-
Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD
-
Perdih A, Kotnik M, Hodošček M Šolmajer T (2007) Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD. Proteins 68 : 243 254.
-
(2007)
Proteins
, vol.68
, pp. 243-254
-
-
Perdih, A.1
Kotnik, M.2
Hodošček, M.3
Šolmajer, T.4
-
277
-
-
0031659702
-
Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: Site-directed mutagenesis and characterization of the mutant enzymes
-
Pompeo F, van Heijenoort J Mengin-Lecreulx D (1998) Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of the mutant enzymes. J Bacteriol 180 : 4799 4803.
-
(1998)
J Bacteriol
, vol.180
, pp. 4799-4803
-
-
Pompeo, F.1
Van Heijenoort, J.2
Mengin-Lecreulx, D.3
-
278
-
-
0035830887
-
Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1- phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and cell growth
-
Pompeo F, Bourne Y, van Heijenoort J, Fassy F Mengin-Lecreulx D (2001) Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and cell growth. J Biol Chem 276 : 3833 3839.
-
(2001)
J Biol Chem
, vol.276
, pp. 3833-3839
-
-
Pompeo, F.1
Bourne, Y.2
Van Heijenoort, J.3
Fassy, F.4
Mengin-Lecreulx, D.5
-
279
-
-
0026344303
-
Over-production, purification and properties of the uridine diphosphate N-acetylmuramoyl-l-alanine: D-glutamate ligase from Escherichia coli
-
Pratviel-Sosa F, Mengin-Lecreulx D van Heijenoort J (1991) Over-production, purification and properties of the uridine diphosphate N-acetylmuramoyl-l-alanine: d-glutamate ligase from Escherichia coli. Eur J Biochem 202 : 1169 1176.
-
(1991)
Eur J Biochem
, vol.202
, pp. 1169-1176
-
-
Pratviel-Sosa, F.1
Mengin-Lecreulx, D.2
Van Heijenoort, J.3
-
280
-
-
0028006477
-
Effect of various analogues of d-glutamic acid on the d-glutamate-adding enzyme from Escherichia coli
-
Pratviel-Sosa F, Acher F, Trigalo F, Blanot D, Azerad R van Heijenoort J (1994) Effect of various analogues of d-glutamic acid on the d-glutamate-adding enzyme from Escherichia coli. FEMS Microbiol Lett 115 : 223 228.
-
(1994)
FEMS Microbiol Lett
, vol.115
, pp. 223-228
-
-
Pratviel-Sosa, F.1
Acher, F.2
Trigalo, F.3
Blanot, D.4
Azerad, R.5
Van Heijenoort, J.6
-
281
-
-
0028814681
-
Staphylococcus haemolyticus contains two d-glutamic acid biosynthetic activities, a glutamate racemase and a d-amino acid transaminase
-
Pucci MJ, Thanassi JA, Ho H-T, Falk PJ Dougherty TJ (1995) Staphylococcus haemolyticus contains two d-glutamic acid biosynthetic activities, a glutamate racemase and a d-amino acid transaminase. J Bacteriol 177 : 336 342.
-
(1995)
J Bacteriol
, vol.177
, pp. 336-342
-
-
Pucci, M.J.1
Thanassi, J.A.2
Ho, H.-T.3
Falk, P.J.4
Dougherty, T.J.5
-
282
-
-
0030931982
-
Identification and characterization of cell wall-cell division gene clusters in pathogenic Gram-positive cocci
-
Pucci MJ, Thanassi JA, Discotto LF, Kessler RE Dougherty TJ (1997) Identification and characterization of cell wall-cell division gene clusters in pathogenic Gram-positive cocci. J Bacteriol 179 : 5632 5635.
-
(1997)
J Bacteriol
, vol.179
, pp. 5632-5635
-
-
Pucci, M.J.1
Thanassi, J.A.2
Discotto, L.F.3
Kessler, R.E.4
Dougherty, T.J.5
-
283
-
-
31544442056
-
A molecular dynamics simulation of the binding modes of d-glutamate and d-glutamine to glutamate racemase
-
Puig E, Garcia-Viloca M, González-Lafont A, López I, Daura X Lluch JM (2005) A molecular dynamics simulation of the binding modes of d-glutamate and d-glutamine to glutamate racemase. J Chem Theory Comput 1 : 737 749.
-
(2005)
J Chem Theory Comput
, vol.1
, pp. 737-749
-
-
Puig, E.1
Garcia-Viloca, M.2
González-Lafont, A.3
López, I.4
Daura, X.5
Lluch, J.M.6
-
284
-
-
31544442452
-
On the ionization state of the substrate in the active site of glutamate racemase. a QM/MM study about the importance of being zwitterionic
-
Puig E, Garcia-Viloca M, González-Lafont A Lluch JM (2006) On the ionization state of the substrate in the active site of glutamate racemase. A QM/MM study about the importance of being zwitterionic. J Phys Chem A 110 : 717 725.
-
(2006)
J Phys Chem a
, vol.110
, pp. 717-725
-
-
Puig, E.1
Garcia-Viloca, M.2
González-Lafont, A.3
Lluch, J.M.4
-
285
-
-
34548277126
-
The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans
-
Raczynska J, Olchowy J, Konariev PV, Svergun DI, Milewski S Rypniewski W (2007) The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans. J Mol Biol 372 : 672 688.
-
(2007)
J Mol Biol
, vol.372
, pp. 672-688
-
-
Raczynska, J.1
Olchowy, J.2
Konariev, P.V.3
Svergun, D.I.4
Milewski, S.5
Rypniewski, W.6
-
286
-
-
0028844306
-
A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase
-
Raetz CR Roderick SL (1995) A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase. Science 270 : 997 1000.
-
(1995)
Science
, vol.270
, pp. 997-1000
-
-
Raetz, C.R.1
Roderick, S.L.2
-
287
-
-
0028609824
-
Detection of the covalent intermediate of UDP-N-acetylglucosamine enolpyruvyl transferase by solution-state and time-resolved solid-state NMR spectroscopy
-
Ramilo C, Appleyard RJ, Wanke C, Krekel F, Amrhein N Evans JN (1994) Detection of the covalent intermediate of UDP-N-acetylglucosamine enolpyruvyl transferase by solution-state and time-resolved solid-state NMR spectroscopy. Biochemistry 33 : 15071 15079.
-
(1994)
Biochemistry
, vol.33
, pp. 15071-15079
-
-
Ramilo, C.1
Appleyard, R.J.2
Wanke, C.3
Krekel, F.4
Amrhein, N.5
Evans, J.N.6
-
288
-
-
1442275671
-
Selection of an antibiotic-hypersusceptible mutant of Pseudomonas aeruginosa: Identification of the GlmR transcriptional regulator
-
Ramos-Aires J, Plésiat P, Kocjancic-Curty L Köhler T (2004) Selection of an antibiotic-hypersusceptible mutant of Pseudomonas aeruginosa: identification of the GlmR transcriptional regulator. Antimicrob Agents Chemother 48 : 843 851.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 843-851
-
-
Ramos-Aires, J.1
Plésiat, P.2
Kocjancic-Curty, L.3
Köhler, T.4
-
289
-
-
0345059135
-
A method for the enzymatic synthesis and HPLC purification of the peptidoglycan precursor UDP-N-acetylmuramic acid
-
Raymond JB, Price NP Pavelka MS Jr. (2003) A method for the enzymatic synthesis and HPLC purification of the peptidoglycan precursor UDP-N-acetylmuramic acid. FEMS Microbiol Lett 229 : 83 89.
-
(2003)
FEMS Microbiol Lett
, vol.229
, pp. 83-89
-
-
Raymond, J.B.1
Price, N.P.2
Pavelka Jr., M.S.3
-
291
-
-
0033576995
-
Preparative enzymatic synthesis and characterization of the cytoplasmic intermediates of murein biosynthesis
-
Reddy S, Waddell ST, Kuo DW, Wong KK Pompliano DL (1999) Preparative enzymatic synthesis and characterization of the cytoplasmic intermediates of murein biosynthesis. J Am Chem Soc 121 : 1175 1178.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 1175-1178
-
-
Reddy, S.1
Waddell, S.T.2
Kuo, D.W.3
Wong, K.K.4
Pompliano, D.L.5
-
292
-
-
0027772882
-
Directed evolution of biosynthetic pathways: Recruitment of cysteine thioethers for constructing the cell wall of Escherichia coli
-
Richaud C, Mengin-Lecreulx D, Pochet S, Johnson EJ, Cohen GN Marlière P (1993) Directed evolution of biosynthetic pathways: recruitment of cysteine thioethers for constructing the cell wall of Escherichia coli. J Biol Chem 268 : 26827 26835.
-
(1993)
J Biol Chem
, vol.268
, pp. 26827-26835
-
-
Richaud, C.1
Mengin-Lecreulx, D.2
Pochet, S.3
Johnson, E.J.4
Cohen, G.N.5
Marlière, P.6
-
293
-
-
0034605454
-
Formation and stability of organic zwitterions in aqueous solution: Enolates of the amino acid glycine and its derivatives
-
Rios A, Amyes TL Richard JP (2000) Formation and stability of organic zwitterions in aqueous solution: enolates of the amino acid glycine and its derivatives. J Am Chem Soc 122 : 9373 9385.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 9373-9385
-
-
Rios, A.1
Amyes, T.L.2
Richard, J.P.3
-
295
-
-
0034255263
-
The molecular basis of vancomycin resistance in clinically relevant Enterococci: Crystal structure of d-alanyl-d-lactate ligase (VanA)
-
Roper DI, Huyton T, Vagin A Dodson G (2000) The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of d-alanyl-d-lactate ligase (VanA). Proc Natl Acad Sci USA 97 : 8921 8925.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8921-8925
-
-
Roper, D.I.1
Huyton, T.2
Vagin, A.3
Dodson, G.4
-
296
-
-
27644453362
-
Substrate-induced conformational changes in Bacillus subtilis glutamate racemase and their implications for drug discovery
-
Ruzheinikov SN, Taal MA, Sedelnikova SE, Baker PJ Rice DW (2005) Substrate-induced conformational changes in Bacillus subtilis glutamate racemase and their implications for drug discovery. Structure 13 : 1707 1713.
-
(2005)
Structure
, vol.13
, pp. 1707-1713
-
-
Ruzheinikov, S.N.1
Taal, M.A.2
Sedelnikova, S.E.3
Baker, P.J.4
Rice, D.W.5
-
297
-
-
33846259335
-
Alanine racemase from Helicobacter pylori NCTC
-
11637: purification, characterization and gene cloning.
-
Saito M, Nishimura K, Hasegawa Y, Shinohara T, Wakabayashi S, Kurihara T, Ishizuka M Nagata Y (2007) Alanine racemase from Helicobacter pylori NCTC 11637: purification, characterization and gene cloning. Life Sci 80 : 788 794.
-
(2007)
Life Sci
, vol.80
, pp. 788-794
-
-
Saito, M.1
Nishimura, K.2
Hasegawa, Y.3
Shinohara, T.4
Wakabayashi, S.5
Kurihara, T.6
Ishizuka, M.7
Nagata, Y.8
-
298
-
-
0032832620
-
Lysine 22 in UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae is crucial for enzymatic activity and the formation of covalent adducts with the substrate phosphoenolpyruvate and the antibiotic fosfomycin
-
Samland AK, Amrhein N Macheroux P (1999) Lysine 22 in UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae is crucial for enzymatic activity and the formation of covalent adducts with the substrate phosphoenolpyruvate and the antibiotic fosfomycin. Biochemistry 38 : 13162 13169.
-
(1999)
Biochemistry
, vol.38
, pp. 13162-13169
-
-
Samland, A.K.1
Amrhein, N.2
MacHeroux, P.3
-
299
-
-
0035852821
-
Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae
-
Samland AK, Etezady-Esfarjani T, Amrhein N Macheroux P (2001) Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae. Biochemistry 40 : 1550 1559.
-
(2001)
Biochemistry
, vol.40
, pp. 1550-1559
-
-
Samland, A.K.1
Etezady-Esfarjani, T.2
Amrhein, N.3
MacHeroux, P.4
-
300
-
-
0036199409
-
Determination of ligand-MurB interactions by isothermal denaturation: Application as a secondary assay to complement high throughput screening
-
Sarver DW, Rogers JM Epps DM (2002) Determination of ligand-MurB interactions by isothermal denaturation: application as a secondary assay to complement high throughput screening. J Biomol Screen 7 : 21 28.
-
(2002)
J Biomol Screen
, vol.7
, pp. 21-28
-
-
Sarver, D.W.1
Rogers, J.M.2
Epps, D.M.3
-
301
-
-
27644499529
-
D-Amino acid dipeptide production utilizing d-alanine-d-alanine ligases with novel substrate specificity
-
Sato M, Kirimura K Kino K (2005) d-Amino acid dipeptide production utilizing d-alanine-d-alanine ligases with novel substrate specificity. J Biosci Bioeng 99 : 623 628.
-
(2005)
J Biosci Bioeng
, vol.99
, pp. 623-628
-
-
Sato, M.1
Kirimura, K.2
Kino, K.3
-
302
-
-
33751421505
-
Substrate specificity of thermostable d-alanine-d-alanine ligase from Thermotoga maritima ATCC
-
43589.
-
Sato M, Kirimura K Kino K (2006) Substrate specificity of thermostable d-alanine-d-alanine ligase from Thermotoga maritima ATCC 43589. Biosci Biotechnol Biochem 70 : 2790 2792.
-
(2006)
Biosci Biotechnol Biochem
, vol.70
, pp. 2790-2792
-
-
Sato, M.1
Kirimura, K.2
Kino, K.3
-
303
-
-
39149088656
-
The structure of Penicillin-Binding Proteins and their role in peptidoglycan biosynthesis
-
doi:
-
Sauvage E, Charlier P, Terrak M Ayala JA (2008) The structure of Penicillin-Binding Proteins and their role in peptidoglycan biosynthesis. FEMS Microbiol Rev, doi :
-
(2008)
FEMS Microbiol Rev
-
-
Sauvage, E.1
Charlier, P.2
Terrak, M.3
Ayala, J.A.4
-
304
-
-
85007736394
-
Kinetics of thermostable alanine racemase of Bacillus stearothermophilus
-
Sawada S, Tanaka Y, Hayashi S, Ryu M, Hasegawa T, Yamamoto Y, Esaki N, Soda K Takahashi S (1994) Kinetics of thermostable alanine racemase of Bacillus stearothermophilus. Biosci Biotechnol Biochem 58 : 807 811.
-
(1994)
Biosci Biotechnol Biochem
, vol.58
, pp. 807-811
-
-
Sawada, S.1
Tanaka, Y.2
Hayashi, S.3
Ryu, M.4
Hasegawa, T.5
Yamamoto, Y.6
Esaki, N.7
Soda, K.8
Takahashi, S.9
-
305
-
-
0015462556
-
Peptidoglycan types of bacterial cell walls and their taxonomic implications
-
Schleifer KH Kandler O (1972) Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol Rev 36 : 407 477.
-
(1972)
Bacteriol Rev
, vol.36
, pp. 407-477
-
-
Schleifer, K.H.1
Kandler, O.2
-
306
-
-
0030587522
-
Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin
-
Schönbrunn E, Sack S, Eschenburg S, Perrakis A, Krekel F, Amrhein N Mandelkow E (1996) Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin. Structure 4 : 1065 1075.
-
(1996)
Structure
, vol.4
, pp. 1065-1075
-
-
Schönbrunn, E.1
Sack, S.2
Eschenburg, S.3
Perrakis, A.4
Krekel, F.5
Amrhein, N.6
Mandelkow, E.7
-
307
-
-
0032522591
-
Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA)
-
Schönbrunn E, Svergun DI, Amrhein N Koch MH (1998) Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA). Eur J Biochem 253 : 406 412.
-
(1998)
Eur J Biochem
, vol.253
, pp. 406-412
-
-
Schönbrunn, E.1
Svergun, D.I.2
Amrhein, N.3
Koch, M.H.4
-
308
-
-
0034612339
-
Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA
-
Schönbrunn E, Eschenburg S, Luger K, Kabsch W Amrhein N (2000a) Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA. Proc Natl Acad Sci USA 97 : 6345 6349.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6345-6349
-
-
Schönbrunn, E.1
Eschenburg, S.2
Luger, K.3
Kabsch, W.4
Amrhein, N.5
-
309
-
-
0040805973
-
Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA
-
Schönbrunn E, Eschenburg S, Krekel F, Luger K Amrhein N (2000b) Role of the loop containing residue 115 in the induced-fit mechanism of the
-
(2000)
Biochemistry
, vol.39
, pp. 2164-2173
-
-
Schönbrunn, E.1
Eschenburg, S.2
Krekel, F.3
Luger, K.4
Amrhein, N.5
-
310
-
-
33748930093
-
Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: Derivatives of UDPMurNAc-pentapeptide containing d-cysteine at position 4 or 5
-
Schouten JA, Bagga S, Lloyd AJ, de Pascale G, Dowson CG, Roper DI Bugg TD (2006) Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: derivatives of UDPMurNAc-pentapeptide containing d-cysteine at position 4 or 5. Mol Biosyst 2 : 484 491.
-
(2006)
Mol Biosyst
, vol.2
, pp. 484-491
-
-
Schouten, J.A.1
Bagga, S.2
Lloyd, A.J.3
De Pascale, G.4
Dowson, C.G.5
Roper, D.I.6
Bugg, T.D.7
-
311
-
-
0041429626
-
Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation
-
Seebeck FP Hilvert D (2003) Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation. J Am Chem Soc 125 : 10158 10159.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 10158-10159
-
-
Seebeck, F.P.1
Hilvert, D.2
-
312
-
-
33750976703
-
Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding
-
Sengupta S, Shah M Nagaraja V (2006) Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding. Nucleic Acids Res 34 : 5567 5576.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 5567-5576
-
-
Sengupta, S.1
Shah, M.2
Nagaraja, V.3
-
313
-
-
0000962307
-
Alanine racemase from an acidophile, Acidiphilium organovorum: Purification and characterisation
-
Seow TK, Inagaki K, Tamura T, Soda K Tanaka H (1998) Alanine racemase from an acidophile, Acidiphilium organovorum: purification and characterisation. Biosci Biotechnol Biochem 62 : 242 247.
-
(1998)
Biosci Biotechnol Biochem
, vol.62
, pp. 242-247
-
-
Seow, T.K.1
Inagaki, K.2
Tamura, T.3
Soda, K.4
Tanaka, H.5
-
314
-
-
0034281939
-
Purification and some characteristics of a monomeric alanine racemase from an extreme thermophile, Thermus thermophilus
-
Seow TK, Inagaki K, Nakamura T, Maeda R, Tamura T Tanaka H (2000) Purification and some characteristics of a monomeric alanine racemase from an extreme thermophile, Thermus thermophilus. J Biosci Bioeng 90 : 344 346.
-
(2000)
J Biosci Bioeng
, vol.90
, pp. 344-346
-
-
Seow, T.K.1
Inagaki, K.2
Nakamura, T.3
Maeda, R.4
Tamura, T.5
Tanaka, H.6
-
315
-
-
17144428500
-
Efficient gene inactivation in Bacillus anthracis
-
Shatalin KY Neyfakh AA (2005) Efficient gene inactivation in Bacillus anthracis. FEMS Microbiol Lett 245 : 315 319.
-
(2005)
FEMS Microbiol Lett
, vol.245
, pp. 315-319
-
-
Shatalin, K.Y.1
Neyfakh, A.A.2
-
316
-
-
0031032448
-
Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-Å resolution
-
Shaw JP, Petsko GA Ringe D (1997) Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-Å resolution. Biochemistry 36 : 1329 1342.
-
(1997)
Biochemistry
, vol.36
, pp. 1329-1342
-
-
Shaw, J.P.1
Petsko, G.A.2
Ringe, D.3
-
317
-
-
0034665744
-
Structural and functional similarities in the ADP-forming amide bond ligase superfamily: Implications for a substrate-induced conformational change in folylpolyglutamate synthetase
-
Sheng Y, Sun X, Shen Y, Bognar AL, Baker EN Smith CA (2000) Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase. J Mol Biol 302 : 427 440.
-
(2000)
J Mol Biol
, vol.302
, pp. 427-440
-
-
Sheng, Y.1
Sun, X.2
Shen, Y.3
Bognar, A.L.4
Baker, E.N.5
Smith, C.A.6
-
318
-
-
0037169976
-
Benzylidene rhodanines as novel inhibitors of UDP-N-acetylmuramate/l- alanine ligase
-
Sim MM, Ng SB, Buss AD, Crasta SC, Goh KL Lee SK (2002) Benzylidene rhodanines as novel inhibitors of UDP-N-acetylmuramate/l-alanine ligase. Bioorg Med Chem Lett 12 : 697 699.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 697-699
-
-
Sim, M.M.1
Ng, S.B.2
Buss, A.D.3
Crasta, S.C.4
Goh, K.L.5
Lee, S.K.6
-
319
-
-
0030589610
-
Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin
-
Skarzynski T, Mistry A, Wonacott A, Hutchinson SE, Kelly VA Duncan K (1996) Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin. Structure 4 : 1465 1474.
-
(1996)
Structure
, vol.4
, pp. 1465-1474
-
-
Skarzynski, T.1
Mistry, A.2
Wonacott, A.3
Hutchinson, S.E.4
Kelly, V.A.5
Duncan, K.6
-
320
-
-
0032562223
-
Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA
-
Skarzynski T, Kim DH, Lees WJ, Walsh CT Duncan K (1998) Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA. Biochemistry 37 : 2572 2577.
-
(1998)
Biochemistry
, vol.37
, pp. 2572-2577
-
-
Skarzynski, T.1
Kim, D.H.2
Lees, W.J.3
Walsh, C.T.4
Duncan, K.5
-
321
-
-
33748324503
-
Structure, function and dynamics in the mur family of bacterial cell wall ligases
-
Smith CA (2006) Structure, function and dynamics in the mur family of bacterial cell wall ligases. J Mol Biol 362 : 640 655.
-
(2006)
J Mol Biol
, vol.362
, pp. 640-655
-
-
Smith, C.A.1
-
322
-
-
39149116447
-
-
Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, September 26-29, San Francisco, USA, p. 330.
-
Snyder NJ, Tebbe MJ, Victor F et al 1999) Synthesis and evaluation of Streptococcus pneumoniae MurD transition state inhibitors. Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, September 26-29, San Francisco, USA, p. 330.
-
(1999)
Synthesis and Evaluation of Streptococcus Pneumoniae MurD Transition State Inhibitors
-
-
Snyder, N.J.1
Tebbe, M.J.2
Victor, F.3
Al, E.4
-
323
-
-
2542587769
-
Crystal structure of an Udp-N-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution
-
Spraggon G, Schwarzenbacher R, Kreusch A et al 2004) Crystal structure of an Udp-N-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution. Proteins 55 : 1078 1081.
-
(2004)
Proteins
, vol.55
, pp. 1078-1081
-
-
Spraggon, G.1
Schwarzenbacher, R.2
Kreusch, A.3
Al, E.4
-
324
-
-
0032555181
-
Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine
-
Stamper GF, Morollo AA Ringe D (1998) Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine. Biochemistry 37 : 10438 10445.
-
(1998)
Biochemistry
, vol.37
, pp. 10438-10445
-
-
Stamper, G.F.1
Morollo, A.A.2
Ringe, D.3
-
326
-
-
27944446768
-
Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD
-
Štrancar K, Blanot D Gobec S (2006) Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD. Bioorg Med Chem Lett 16 : 343 348.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 343-348
-
-
Štrancar, K.1
Blanot, D.2
Gobec, S.3
-
327
-
-
34249719140
-
Phosphinate inhibitors of UDP-N-acetylmuramoyl-l-alanyl-d-glutamate: L-lysine ligase (MurE)
-
Štrancar K, Boniface A, Blanot D Gobec S (2007) Phosphinate inhibitors of UDP-N-acetylmuramoyl-l-alanyl-d-glutamate: l-lysine ligase (MurE). Arch Pharm Chem Life Sci 340 : 127 134.
-
(2007)
Arch Pharm Chem Life Sci
, vol.340
, pp. 127-134
-
-
Štrancar, K.1
Boniface, A.2
Blanot, D.3
Gobec, S.4
-
328
-
-
0000837032
-
Competitive inhibition of enzymatic reactions by oxamycin
-
Strominger JL, Ito E Threnn RH (1960) Competitive inhibition of enzymatic reactions by oxamycin. J Am Chem Soc 82 : 998 999.
-
(1960)
J Am Chem Soc
, vol.82
, pp. 998-999
-
-
Strominger, J.L.1
Ito, E.2
Threnn, R.H.3
-
329
-
-
0036068204
-
Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric
-
Strych U Benedik MJ (2002) Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric. J Bacteriol 184 : 4321 4325.
-
(2002)
J Bacteriol
, vol.184
, pp. 4321-4325
-
-
Strych, U.1
Benedik, M.J.2
-
330
-
-
0033800818
-
Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1
-
Strych U, Huang HC, Krause KL Benedik MJ (2000) Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Curr Microbiol 41 : 290 294.
-
(2000)
Curr Microbiol
, vol.41
, pp. 290-294
-
-
Strych, U.1
Huang, H.C.2
Krause, K.L.3
Benedik, M.J.4
-
331
-
-
0035868566
-
Characterization of the alanine racemases from two mycobacteria
-
Strych U, Penland RL, Jimenez M, Krause KL Benedik MJ (2001) Characterization of the alanine racemases from two mycobacteria. FEMS Microbiol Lett 196 : 93 98.
-
(2001)
FEMS Microbiol Lett
, vol.196
, pp. 93-98
-
-
Strych, U.1
Penland, R.L.2
Jimenez, M.3
Krause, K.L.4
Benedik, M.J.5
-
332
-
-
0029144437
-
Crystal structure of a d-amino acid aminotransferase: How the protein controls stereoselectivity
-
Sugio S, Petsko GA, Manning JM, Soda K Ringe D (1995) Crystal structure of a d-amino acid aminotransferase: how the protein controls stereoselectivity. Biochemistry 34 : 9661 9669.
-
(1995)
Biochemistry
, vol.34
, pp. 9661-9669
-
-
Sugio, S.1
Petsko, G.A.2
Manning, J.M.3
Soda, K.4
Ringe, D.5
-
333
-
-
0031815022
-
Crystal structures of L201A mutant of d-amino acid aminotransferase at 2.0 Å resolution: Implication of the structural role of Leu201 in transamination
-
Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T Esaki N (1998) Crystal structures of L201A mutant of d-amino acid aminotransferase at 2.0 Å resolution: implication of the structural role of Leu201 in transamination. Protein Eng 11 : 613 619.
-
(1998)
Protein Eng
, vol.11
, pp. 613-619
-
-
Sugio, S.1
Kashima, A.2
Kishimoto, K.3
Peisach, D.4
Petsko, G.A.5
Ringe, D.6
Yoshimura, T.7
Esaki, N.8
-
334
-
-
0035853790
-
Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1- phosphate uridyltransferase bound to acetyl-coenzyme a reveals a novel active site architecture
-
Sulzenbacher G, Gal L, Peneff C, Fassy F Bourne Y (2001) Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture. J Biol Chem 276 : 11844 11851.
-
(2001)
J Biol Chem
, vol.276
, pp. 11844-11851
-
-
Sulzenbacher, G.1
Gal, L.2
Peneff, C.3
Fassy, F.4
Bourne, Y.5
-
335
-
-
0033616634
-
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase
-
Sun S Toney MD (1999) Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase. Biochemistry 38 : 4058 4065.
-
(1999)
Biochemistry
, vol.38
, pp. 4058-4065
-
-
Sun, S.1
Toney, M.D.2
-
336
-
-
0035958665
-
Folate-binding triggers the activation of folylpolyglutamate synthetase
-
Sun X, Cross JA, Bognar AL, Baker EN Smith CA (2001) Folate-binding triggers the activation of folylpolyglutamate synthetase. J Mol Biol 310 : 1067 1078.
-
(2001)
J Mol Biol
, vol.310
, pp. 1067-1078
-
-
Sun, X.1
Cross, J.A.2
Bognar, A.L.3
Baker, E.N.4
Smith, C.A.5
-
337
-
-
15844428445
-
Purification to homogeneity and properties of UDP-GlcNAc (GalNAc) pyrophosphorylase
-
Szumilo T, Zeng Y, Pastuszak I, Drake R, Szumilo H Elbein AD (1996) Purification to homogeneity and properties of UDP-GlcNAc (GalNAc) pyrophosphorylase. J Biol Chem 271 : 13147 13154.
-
(1996)
J Biol Chem
, vol.271
, pp. 13147-13154
-
-
Szumilo, T.1
Zeng, Y.2
Pastuszak, I.3
Drake, R.4
Szumilo, H.5
Elbein, A.D.6
-
338
-
-
0024586605
-
Thermostable d-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination
-
Tanizawa K, Masu Y, Asano S, Tanaka H Soda K (1989) Thermostable d-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination. J Biol Chem 264 : 2445 2449.
-
(1989)
J Biol Chem
, vol.264
, pp. 2445-2449
-
-
Tanizawa, K.1
Masu, Y.2
Asano, S.3
Tanaka, H.4
Soda, K.5
-
339
-
-
0036005636
-
Understanding nature's strategies for enzyme-catalyzed racemization and epimerization
-
Tanner ME (2002) Understanding nature's strategies for enzyme-catalyzed racemization and epimerization. Acc Chem Res 35 : 237 246.
-
(2002)
Acc Chem Res
, vol.35
, pp. 237-246
-
-
Tanner, M.E.1
-
340
-
-
0028263397
-
The synthesis and stability of aziridino-glutamate, an irreversible inhibitor of glutamate racemase
-
Tanner ME Miao S (1994) The synthesis and stability of aziridino-glutamate, an irreversible inhibitor of glutamate racemase. Tetrahedron Lett 35 : 4073 4076.
-
(1994)
Tetrahedron Lett
, vol.35
, pp. 4073-4076
-
-
Tanner, M.E.1
Miao, S.2
-
341
-
-
0029867778
-
Phosphinate inhibitors of the d-glutamic acid-adding enzyme of peptidoglycan biosynthesis
-
Tanner ME, Vaganay S, van Heijenoort J Blanot D (1996) Phosphinate inhibitors of the d-glutamic acid-adding enzyme of peptidoglycan biosynthesis. J Org Chem 61 : 1756 1760.
-
(1996)
J Org Chem
, vol.61
, pp. 1756-1760
-
-
Tanner, M.E.1
Vaganay, S.2
Van Heijenoort, J.3
Blanot, D.4
-
342
-
-
0033894595
-
Identification of the Pseudomonas aeruginosa glmM gene, encoding phosphoglucosamine mutase
-
Tavares IM, Jolly L, Pompeo F, Leitão JH, Fialho AM, Sá-Correia I Mengin-Lecreulx D (2000) Identification of the Pseudomonas aeruginosa glmM gene, encoding phosphoglucosamine mutase. J Bacteriol 182 : 4453 4457.
-
(2000)
J Bacteriol
, vol.182
, pp. 4453-4457
-
-
Tavares, I.M.1
Jolly, L.2
Pompeo, F.3
Leitão, J.H.4
Fialho, A.M.5
Sá-Correia, I.6
Mengin-Lecreulx, D.7
-
343
-
-
0029448523
-
Overproduction and one-step purification of Escherichia coli UDP-N-acetylglucosamine enolpyruvyl reductase
-
Tayeh MA, Dotson GD, Clemens JC Woodard RW (1995) Overproduction and one-step purification of Escherichia coli UDP-N-acetylglucosamine enolpyruvyl reductase. Protein Expr Purif 6 : 757 762.
-
(1995)
Protein Expr Purif
, vol.6
, pp. 757-762
-
-
Tayeh, M.A.1
Dotson, G.D.2
Clemens, J.C.3
Woodard, R.W.4
-
344
-
-
0031030606
-
Nucleotide sequence of the Bacillus licheniformis ATTC
-
10716 dat gene and comparison of the predicted amino acid sequence with those of other bacterial species.
-
Taylor PP Fortheringham IG (1997) Nucleotide sequence of the Bacillus licheniformis ATTC 10716 dat gene and comparison of the predicted amino acid sequence with those of other bacterial species. Biochim Biophys Acta 1350 : 38 40.
-
(1997)
Biochim Biophys Acta
, vol.1350
, pp. 38-40
-
-
Taylor, P.P.1
Fortheringham, I.G.2
-
345
-
-
0032529009
-
Involvement of the C terminus in intramolecular nitrogen channeling in glucosamine 6-phosphate synthase: Evidence from a 1.6 Å crystal structure of the isomerase domain
-
Teplyakov A, Obmolova G, Badet-Denisot MA, Badet B Polikarpov I (1998) Involvement of the C terminus in intramolecular nitrogen channeling in glucosamine 6-phosphate synthase: evidence from a 1.6 Å crystal structure of the isomerase domain. Structure 6 : 1047 1055.
-
(1998)
Structure
, vol.6
, pp. 1047-1055
-
-
Teplyakov, A.1
Obmolova, G.2
Badet-Denisot, M.A.3
Badet, B.4
Polikarpov, I.5
-
347
-
-
0031852771
-
Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires d-alanine for growth
-
Thompson RJ, Bouwer HG, Portnoy DA Frankel FR (1998) Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires d-alanine for growth. Infect Immun 66 : 3552 3561.
-
(1998)
Infect Immun
, vol.66
, pp. 3552-3561
-
-
Thompson, R.J.1
Bouwer, H.G.2
Portnoy, D.A.3
Frankel, F.R.4
-
348
-
-
0023617614
-
3-Halovinylglycines. Efficient irreversible inhibitors of E. coli alanine racemase
-
Thornberry NA, Bull HG, Taub D, Greenlee WJ, Patchett AA Cordes EH (1987) 3-Halovinylglycines. Efficient irreversible inhibitors of E. coli alanine racemase. J Am Chem Soc 109 : 7543 7544.
-
(1987)
J Am Chem Soc
, vol.109
, pp. 7543-7544
-
-
Thornberry, N.A.1
Bull, H.G.2
Taub, D.3
Greenlee, W.J.4
Patchett, A.A.5
Cordes, E.H.6
-
349
-
-
0025887428
-
Mechanism-based inactivation of alanine racemase by 3-halovinylglycines
-
Thornberry NA, Bull HG, Taub D, Wilson KE, Gimenez-Gallego G, Rosegay A, Soderman DD Patchett AA (1991) Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem 266 : 21657 21665.
-
(1991)
J Biol Chem
, vol.266
, pp. 21657-21665
-
-
Thornberry, N.A.1
Bull, H.G.2
Taub, D.3
Wilson, K.E.4
Gimenez-Gallego, G.5
Rosegay, A.6
Soderman, D.D.7
Patchett, A.A.8
-
350
-
-
0025781289
-
Coordinated regulation of glutamine: Fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation
-
Traxinger RR Marshall S (1991) Coordinated regulation of glutamine: fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation. J Biol Chem 266 : 10148 10154.
-
(1991)
J Biol Chem
, vol.266
, pp. 10148-10154
-
-
Traxinger, R.R.1
Marshall, S.2
-
351
-
-
2942569592
-
Synthesis of 4-fluorinated UDP-MurNAc pentapeptide as an inhibitor of bacterial growth
-
Ueda T, Feng F, Sadamoto R, Niikura K, Monde K Nishimura S-I (2004) Synthesis of 4-fluorinated UDP-MurNAc pentapeptide as an inhibitor of bacterial growth. Org Lett 6 : 1753 1756.
-
(2004)
Org Lett
, vol.6
, pp. 1753-1756
-
-
Ueda, T.1
Feng, F.2
Sadamoto, R.3
Niikura, K.4
Monde, K.5
Nishimura, S.-I.6
-
352
-
-
0027121143
-
Eight bacterial proteins, including UDP-N-acetylglucosamine acyltransferase (LpxA) and three other transferases of Escherichia coli, consist of a six-residue periodicity theme
-
Vaara M (1992) Eight bacterial proteins, including UDP-N- acetylglucosamine acyltransferase (LpxA) and three other transferases of Escherichia coli, consist of a six-residue periodicity theme. FEMS Microbiol Lett 76 : 249 254.
-
(1992)
FEMS Microbiol Lett
, vol.76
, pp. 249-254
-
-
Vaara, M.1
-
353
-
-
0029739897
-
Study of the reaction mechanism of the d-glutamic acid-adding enzyme from Escherichia coli
-
Vaganay S, Tanner ME, van Heijenoort J Blanot D (1996) Study of the reaction mechanism of the d-glutamic acid-adding enzyme from Escherichia coli. Microb Drug Resist 2 : 51 54.
-
(1996)
Microb Drug Resist
, vol.2
, pp. 51-54
-
-
Vaganay, S.1
Tanner, M.E.2
Van Heijenoort, J.3
Blanot, D.4
-
354
-
-
0025744166
-
Synthesis and antiobacterial evaluation of phosphonic acid analogues of diaminopimelic acid
-
van Assche I, Soroka M, Haemers A, Hooper M, Blanot D van Heijenoort J (1991) Synthesis and antiobacterial evaluation of phosphonic acid analogues of diaminopimelic acid. Eur J Med Chem 26 : 505 515.
-
(1991)
Eur J Med Chem
, vol.26
, pp. 505-515
-
-
Van Assche, I.1
Soroka, M.2
Haemers, A.3
Hooper, M.4
Blanot, D.5
Van Heijenoort, J.6
-
355
-
-
0034762821
-
Recent advances in the formation of the bacterial peptidoglycan monomer subunit
-
van Heijenoort J (2001) Recent advances in the formation of the bacterial peptidoglycan monomer subunit. Nat Prod Rep 18 : 503 519.
-
(2001)
Nat Prod Rep
, vol.18
, pp. 503-519
-
-
Van Heijenoort, J.1
-
356
-
-
0033604832
-
Effects of the E177K mutation in d-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity
-
van Ophem PW, Peisach D, Erickson SD, Soda K, Ringe D Manning JM (1999) Effects of the E177K mutation in d-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity. Biochemistry 38 : 1323 1331.
-
(1999)
Biochemistry
, vol.38
, pp. 1323-1331
-
-
Van Ophem, P.W.1
Peisach, D.2
Erickson, S.D.3
Soda, K.4
Ringe, D.5
Manning, J.M.6
-
357
-
-
39149112589
-
-
d-Glutamic acid analogs as Streptococcus pneumoniae UDP-N-acetyl muramoyl-alanine:d-glutamate ligase (MurD) inhibitors. Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, September 26-29, San Francisco, USA, p. 330.
-
Victor F, Tebbe MJ, Birch GM, Smith MC, Letourneau DL Wu CE (1999) d-Glutamic acid analogs as Streptococcus pneumoniae UDP-N-acetyl muramoyl-alanine:d-glutamate ligase (MurD) inhibitors. Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, September 26-29, San Francisco, USA, p. 330.
-
(1999)
-
-
Victor, F.1
Tebbe, M.J.2
Birch, G.M.3
Smith, M.C.4
Letourneau, D.L.5
Wu, C.E.6
-
358
-
-
0035838447
-
Biosynthesis of d-alanyl-lipoteichoic acid: The tertiary structure of apo-d-alanyl carrier protein
-
Volkman BF, Zhang Q, Debabov DV, Rivera E, Kresheck GC Neuhaus FC (2001) Biosynthesis of d-alanyl-lipoteichoic acid: the tertiary structure of apo-d-alanyl carrier protein. Biochemistry 40 : 7964 7972.
-
(2001)
Biochemistry
, vol.40
, pp. 7964-7972
-
-
Volkman, B.F.1
Zhang, Q.2
Debabov, D.V.3
Rivera, E.4
Kresheck, G.C.5
Neuhaus, F.C.6
-
360
-
-
0022617956
-
(β-Chloro-α-aminoethyl)phosphonic acids as inhibitors of alanine racemase and d-alanine :d-alanine ligase
-
Vo-Quang Y, Carniato D, Vo-Quang L, Lacoste AM, Neuzil E Le Goffic F (1986a) (β-Chloro-α-aminoethyl)phosphonic acids as inhibitors of alanine racemase and d-alanine :d-alanine ligase. J Med Chem 29 : 148 151.
-
(1986)
J Med Chem
, vol.29
, pp. 148-151
-
-
Vo-Quang, Y.1
Carniato, D.2
Vo-Quang, L.3
Lacoste, A.M.4
Neuzil, E.5
Le Goffic, F.6
-
361
-
-
0022462318
-
(1-Amino-2-propenyl) phosphonic acid, an inhibitor of alanine racemase and d-alanine : dd-alanine ligase
-
Vo-Quang Y, Carniato D, Vo-Quang L, Lacoste AM, Neuzil E Le Goffic F (1986b) (1-Amino-2-propenyl) phosphonic acid, an inhibitor of alanine racemase and d-alanine : d-alanine ligase. J Med Chem 29 : 579 581.
-
(1986)
J Med Chem
, vol.29
, pp. 579-581
-
-
Vo-Quang, Y.1
Carniato, D.2
Vo-Quang, L.3
Lacoste, A.M.4
Neuzil, E.5
Le Goffic, F.6
-
362
-
-
0034684762
-
Inhibition of Escherichia coli glucosamine synthetase by novel electrophilic analogues of glutamine - Comparison with 6-diazo-5-oxo-norleucine
-
Walker B, Brown MF, Lynas JF, Martin SL, McDowell A, Badet B Hill AJ (2000) Inhibition of Escherichia coli glucosamine synthetase by novel electrophilic analogues of glutamine - comparison with 6-diazo-5-oxo-norleucine. Bioorg Med Chem Lett 10 : 2795 2798.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 2795-2798
-
-
Walker, B.1
Brown, M.F.2
Lynas, J.F.3
Martin, S.L.4
McDowell, A.5
Badet, B.6
Hill, A.J.7
-
363
-
-
0024561489
-
Enzymes of the d-alanine branch of bacterial cell wall peptidoglycan assembly
-
Walsh CT (1989) Enzymes of the d-alanine branch of bacterial cell wall peptidoglycan assembly. J Biol Chem 264 : 2393 2396.
-
(1989)
J Biol Chem
, vol.264
, pp. 2393-2396
-
-
Walsh, C.T.1
-
364
-
-
0030073022
-
The versatility of phosphoenolpyruvate and its vinyl ether products in biosynthesis
-
Walsh CT, Benson TE, Kim DH Lees WJ (1996) The versatility of phosphoenolpyruvate and its vinyl ether products in biosynthesis. Chem Biol 3 : 83 91.
-
(1996)
Chem Biol
, vol.3
, pp. 83-91
-
-
Walsh, C.T.1
Benson, T.E.2
Kim, D.H.3
Lees, W.J.4
-
365
-
-
0032850461
-
Comparison of the d-glutamate-adding enzymes from selected Gram-positive and Gram-negative bacteria
-
Walsh AW, Falk PJ, Thanassi J, Discotto L, Pucci MJ Ho H-T (1999) Comparison of the d-glutamate-adding enzymes from selected Gram-positive and Gram-negative bacteria. J Bacteriol 181 : 5395 5401.
-
(1999)
J Bacteriol
, vol.181
, pp. 5395-5401
-
-
Walsh, A.W.1
Falk, P.J.2
Thanassi, J.3
Discotto, L.4
Pucci, M.J.5
Ho, H.-T.6
-
366
-
-
0017854719
-
Suicide substrates for the alanine racemase of Escherichia coli B
-
Wang E Walsh C (1978) Suicide substrates for the alanine racemase of Escherichia coli B. Biochemistry 17 : 1313 1321.
-
(1978)
Biochemistry
, vol.17
, pp. 1313-1321
-
-
Wang, E.1
Walsh, C.2
-
367
-
-
0019842532
-
Characteristics of β,β-difluoroalanine and β,β, β-trifluoroalanine as suicide substrates of Escherichia coli B alanine racemase
-
Wang EA Walsh C (1981) Characteristics of β,β-difluoroalanine and β,β,β-trifluoroalanine as suicide substrates of Escherichia coli B alanine racemase. Biochemistry 20 : 7539 7546.
-
(1981)
Biochemistry
, vol.20
, pp. 7539-7546
-
-
Wang, E.A.1
Walsh, C.2
-
368
-
-
0027130834
-
Evidence that the reaction of the UDP-N-acetylglucosamine 1-carboxyvinyltransferase proceeds through the O-phosphothioketal of pyruvic acid bound to Cys115 of the enzyme
-
Wanke C Amrhein N (1993) Evidence that the reaction of the UDP-N-acetylglucosamine 1-carboxyvinyltransferase proceeds through the O-phosphothioketal of pyruvic acid bound to Cys115 of the enzyme. Eur J Biochem 218 : 861 870.
-
(1993)
Eur J Biochem
, vol.218
, pp. 861-870
-
-
Wanke, C.1
Amrhein, N.2
-
369
-
-
0026531912
-
The UDP-N-acetylglucosamine 1-carboxyvinyl-transferase of Enterobacter cloacae. Molecular cloning, sequencing of the gene and overexpression of the enzyme
-
Wanke C, Falchetto R Amrhein N (1992) The UDP-N-acetylglucosamine 1-carboxyvinyl-transferase of Enterobacter cloacae. Molecular cloning, sequencing of the gene and overexpression of the enzyme. FEBS Lett 301 : 271 276.
-
(1992)
FEBS Lett
, vol.301
, pp. 271-276
-
-
Wanke, C.1
Falchetto, R.2
Amrhein, N.3
-
370
-
-
0021746281
-
Biosynthesis of peptidoglycan: Points of attack of wall inhibitors
-
Ward JB (1984) Biosynthesis of peptidoglycan: points of attack of wall inhibitors. Pharmac Ther 25 : 327 369.
-
(1984)
Pharmac Ther
, vol.25
, pp. 327-369
-
-
Ward, J.B.1
-
371
-
-
0021769534
-
Catabolic alanine racemase from Salmonella typhimurium: DNA sequence, enzyme purification, and characterization
-
Wasserman SA, Daub E, Grisafi P, Botstein D Walsh CT (1984) Catabolic alanine racemase from Salmonella typhimurium: DNA sequence, enzyme purification, and characterization. Biochemistry 23 : 5182 5187.
-
(1984)
Biochemistry
, vol.23
, pp. 5182-5187
-
-
Wasserman, S.A.1
Daub, E.2
Grisafi, P.3
Botstein, D.4
Walsh, C.T.5
-
372
-
-
0032757833
-
Tyrosine 265 of alanine racemase serves as a base abstracting α-hydrogen from l-alanine: The counterpart residue to lysine 39 specific to d-alanine
-
Watanabe A, Yoshimura T, Mikami B Esaki N (1999a) Tyrosine 265 of alanine racemase serves as a base abstracting α-hydrogen from l-alanine: the counterpart residue to lysine 39 specific to d-alanine. J Biochem (Tokyo) 126 : 781 786.
-
(1999)
J Biochem (Tokyo)
, vol.126
, pp. 781-786
-
-
Watanabe, A.1
Yoshimura, T.2
Mikami, B.3
Esaki, N.4
-
374
-
-
0037166337
-
Reaction mechanism of alanine racemase from Bacillus stearothermophilus: X-ray crystallographic studies of the enzyme bound with N-(5′- phosphopyridoxyl)alanine
-
Watanabe A, Yoshimura T, Mikami B, Hayashi H, Kagamiyama H Esaki N (2002) Reaction mechanism of alanine racemase from Bacillus stearothermophilus: X-ray crystallographic studies of the enzyme bound with N-(5′-phosphopyridoxyl) alanine. J Biol Chem 277 : 19166 19172.
-
(2002)
J Biol Chem
, vol.277
, pp. 19166-19172
-
-
Watanabe, A.1
Yoshimura, T.2
Mikami, B.3
Hayashi, H.4
Kagamiyama, H.5
Esaki, N.6
-
375
-
-
0024323460
-
Cloning of the glutamine: Fructose-6-phosphate amidotransferase gene from yeast. Pheromonal regulation of its transcription
-
Watzele G Tanner W (1989) Cloning of the glutamine: fructose-6-phosphate amidotransferase gene from yeast. Pheromonal regulation of its transcription. J Biol Chem 264 : 8753 8758.
-
(1989)
J Biol Chem
, vol.264
, pp. 8753-8758
-
-
Watzele, G.1
Tanner, W.2
-
376
-
-
0021984140
-
Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12
-
Wild J, Hennig J, Łobocka M, Walczak W Kłopotowski T (1985) Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12. Mol Gen Genet 198 : 315 322.
-
(1985)
Mol Gen Genet
, vol.198
, pp. 315-322
-
-
Wild, J.1
Hennig, J.2
Łobocka, M.3
Walczak, W.4
Kłopotowski, T.5
-
377
-
-
0015008462
-
The binding of substrates and modifiers to glucosamine synthetase
-
Winterburn PJ Phelps CF (1971) The binding of substrates and modifiers to glucosamine synthetase. Biochem J 121 : 721 730.
-
(1971)
Biochem J
, vol.121
, pp. 721-730
-
-
Winterburn, P.J.1
Phelps, C.F.2
-
378
-
-
0029855793
-
The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism
-
Wipat A, Carter N, Brignell SC, Guy BJ, Piper K, Sanders J, Emmerson PT Harwood CR (1996) The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism. Microbiology 142 : 3067 3078.
-
(1996)
Microbiology
, vol.142
, pp. 3067-3078
-
-
Wipat, A.1
Carter, N.2
Brignell, S.C.3
Guy, B.J.4
Piper, K.5
Sanders, J.6
Emmerson, P.T.7
Harwood, C.R.8
-
379
-
-
0032583606
-
Engineering a cell-free murein biosynthetic pathway: Combinatorial enzymology in drug discovery
-
Wong KK, Kuo DW, Chabin RM, Fournier C, Gegnas LD, Waddell ST, Marsilio F, Leiting B Pompliano DL (1998) Engineering a cell-free murein biosynthetic pathway: combinatorial enzymology in drug discovery. J Am Chem Soc 120 : 13527 13528.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 13527-13528
-
-
Wong, K.K.1
Kuo, D.W.2
Chabin, R.M.3
Fournier, C.4
Gegnas, L.D.5
Waddell, S.T.6
Marsilio, F.7
Leiting, B.8
Pompliano, D.L.9
-
380
-
-
0042934291
-
Molecular characterization of alanine racemase from Bifidobacterium bifidum
-
Yamashita T, Ashiuchi M, Ohnishi K, Kato S, Nagata S Misono H (2003) Molecular characterization of alanine racemase from Bifidobacterium bifidum. J Mol Catal B Enzymatic 23 : 213 222.
-
(2003)
J Mol Catal B Enzymatic
, vol.23
, pp. 213-222
-
-
Yamashita, T.1
Ashiuchi, M.2
Ohnishi, K.3
Kato, S.4
Nagata, S.5
Misono, H.6
-
381
-
-
0034423412
-
Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 Å resolution
-
Yan Y, Munshi S, Leiting B, Anderson MS, Chrzas J Chen Z (2000) Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 Å resolution. J Mol Biol 304 : 435 445.
-
(2000)
J Mol Biol
, vol.304
, pp. 435-445
-
-
Yan, Y.1
Munshi, S.2
Leiting, B.3
Anderson, M.S.4
Chrzas, J.5
Chen, Z.6
-
382
-
-
31944448127
-
3,5-Dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against Gram-positive bacteria
-
Yang Y, Severin A, Chopra R et al 2006) 3,5-Dioxopyrazolidines, novel inhibitors of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) with activity against Gram-positive bacteria. Antimicrob Agents Chemother 50 : 556 564.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 556-564
-
-
Yang, Y.1
Severin, A.2
Chopra, R.3
Al, E.4
-
383
-
-
0035798125
-
Gene cloning and characterization of alanine racemases from Shigella dysenteriae, Shigella boydii, Shigella flexneri and Shigella sonnei
-
Yokoigawa K, Hirasawa R, Ueno H, Okubo Y, Umesako S Soda K (2001) Gene cloning and characterization of alanine racemases from Shigella dysenteriae, Shigella boydii, Shigella flexneri and Shigella sonnei. Biochem Biophys Res Commun 288 : 676 684.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 676-684
-
-
Yokoigawa, K.1
Hirasawa, R.2
Ueno, H.3
Okubo, Y.4
Umesako, S.5
Soda, K.6
-
384
-
-
0041876085
-
Amino acid racemases: Functions and mechanisms
-
Yoshimura T Esaki N (2003) Amino acid racemases: functions and mechanisms. J Biosci Bioeng 96 : 103 109.
-
(2003)
J Biosci Bioeng
, vol.96
, pp. 103-109
-
-
Yoshimura, T.1
Esaki, N.2
-
385
-
-
0025774861
-
Existence of two d-alanine : dd-alanine ligases in Escherichia coli: Cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes
-
Zawadzke LE, Bugg TDH Walsh CT (1991) Existence of two d-alanine : d-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes. Biochemistry 30 : 1673 1682.
-
(1991)
Biochemistry
, vol.30
, pp. 1673-1682
-
-
Zawadzke, L.E.1
Bugg, T.D.H.2
Walsh, C.T.3
-
386
-
-
0025311478
-
Antibacterial activity of phosphono dipeptides based on 1-amino-1-methylethanephosphonic acid
-
Zboińska E, Sztajer H, Lejczak B Kafarski P (1990) Antibacterial activity of phosphono dipeptides based on 1-amino-1-methylethanephosphonic acid. FEMS Microbiol Lett 58 : 23 28.
-
(1990)
FEMS Microbiol Lett
, vol.58
, pp. 23-28
-
-
Zboińska, E.1
Sztajer, H.2
Lejczak, B.3
Kafarski, P.4
-
387
-
-
0032567399
-
A phosphinate inhibitor of the meso-diaminopimelic acid-adding enzyme (MurE) of peptidoglycan biosynthesis
-
Zeng B, Wong KK, Pompliano DL, Reddy S Tanner ME (1998) A phosphinate inhibitor of the meso-diaminopimelic acid-adding enzyme (MurE) of peptidoglycan biosynthesis. J Org Chem 63 : 10081 10086.
-
(1998)
J Org Chem
, vol.63
, pp. 10081-10086
-
-
Zeng, B.1
Wong, K.K.2
Pompliano, D.L.3
Reddy, S.4
Tanner, M.E.5
-
388
-
-
0037052063
-
Synthesis and antimicrobial activities of N-substituted imides
-
Zentz F, Valla A, Le Guillou R, Labia R, Mathot AG Sirot D (2002) Synthesis and antimicrobial activities of N-substituted imides. Farmaco 57 : 421 426.
-
(2002)
Farmaco
, vol.57
, pp. 421-426
-
-
Zentz, F.1
Valla, A.2
Le Guillou, R.3
Labia, R.4
Mathot, A.G.5
Sirot, D.6
-
389
-
-
0032523821
-
Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-l-arginyl-poly-l-aspartate (cyanophycin)
-
Ziegler K, Diener A, Herpin C, Richter R, Deutzmann R Lockau W (1998) Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-l-arginyl-poly-l- aspartate (cyanophycin). Eur J Biochem 254 : 154 159.
-
(1998)
Eur J Biochem
, vol.254
, pp. 154-159
-
-
Ziegler, K.1
Diener, A.2
Herpin, C.3
Richter, R.4
Deutzmann, R.5
Lockau, W.6
|