Phosphinate inhibitors of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: L-lysine ligase (MurE)

Archiv der Pharmazie

Volumn 340, Issue 3, 2007, Pages 127-134

  Štrancar, Katja ^a   Boniface, Audrey ^b   Blanot, Didier ^b   Gobec, Stanislav ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

Author keywords

Antibacterials; Inhibitors; MurD; MurE

Indexed keywords

2 [[HYDROXY(2 METHYL 1 [[(3 NITROBENZYL)SULFONYL]AMINO]BUTYL)PHOSPHORYL]METHYL]PENTANEDIOIC ACID; 2 [[HYDROXY(2 METHYL 1 [[(4 NITROBENZYL)SULFONYL]AMINO]BUTYL)PHOSPHORYL]METHYL]PENTANEDIOIC ACID; 2 [[HYDROXY(2 METHYL 1 [[(4 NITROBENZYL)SULFONYL]AMINO]PROPYL)PHOSPHORYL]METHYL]PENTANEDIOIC ACID; GLUTARIC ACID; LIGASE; PEPTIDOGLYCAN; PHOSPHINE DERIVATIVE; UDP N ACETYLMURAMOYL ALANYL DEXTRO GLUTAMATE:LYSINE LIGASE; UDP N ACETYLMURAMOYL ALANYL:DEXTRO GLUTAMATE LIGASE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ENZYME INHIBITOR; PEPTIDE SYNTHASE; PHOSPHINIC ACID DERIVATIVE; UDP N ACETYLMURAMOYL L ALANYL D GLUTAMYL LYSINE LIGASE; UDP N ACETYLMURAMOYLALANINE D GLUTAMATE LIGASE; UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMYL-LYSINE LIGASE; UDP-N-ACETYLMURAMOYLALANINE-D-GLUTAMATE LIGASE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CATALYSIS; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; DRUG ANTAGONISM; ENZYMOLOGY; ISOLATION AND PURIFICATION; PROTEIN CONFORMATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; COMPUTER SIMULATION; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDE SYNTHASES; PHOSPHINIC ACIDS; PROTEIN CONFORMATION; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34249719140     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200600191     Document Type: Article

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