-
1
-
-
0037148328
-
Telomerase is not an oncogene
-
Harley, C. B. Telomerase is not an oncogene. Oncogene, 21: 494-502, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 494-502
-
-
Harley, C.B.1
-
2
-
-
0033455559
-
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
-
Herbert, B. S., Pitts, A. E., Baker, S. I., Hamilton, S. E., Wright, W. E., Shay, J. W., and Corey, D. R. Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc. Natl. Acad. Sci. USA, 96: 14276-14281, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14276-14281
-
-
Herbert, B.S.1
Pitts, A.E.2
Baker, S.I.3
Hamilton, S.E.4
Wright, W.E.5
Shay, J.W.6
Corey, D.R.7
-
3
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn, W. C., Stewart, S. A., Brooks, M. W., York, S. G., Eaton, E., Karachi, A., Beijersbergen, R. L., Knoll, J. H. M., Meyerson, M., and Weinberg, R. Inhibition of telomerase limits the growth of human cancer cells. Nat. Med., 5: 1164-1170, 1999.
-
(1999)
Nat. Med.
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Karachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.M.8
Meyerson, M.9
Weinberg, R.10
-
4
-
-
0037148327
-
Complex regulatory mechanisms of telomerase activity in normal and cancer cells: How can we apply them for cancer therapy?
-
Kyo, S., and Inoue, M. Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy? Oncogene, 21: 688-697, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 688-697
-
-
Kyo, S.1
Inoue, M.2
-
5
-
-
0033532056
-
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
-
Kang, S. S., Twon, T., Kwon, D. Y., and Do, S. L. Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J. Biol. Chem., 274: 13085-13090, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13085-13090
-
-
Kang, S.S.1
Twon, T.2
Kwon, D.Y.3
Do, S.L.4
-
6
-
-
0035871710
-
Telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation
-
Liu, K., Hodes, R. J., and Weng, N. Telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation. J. Immunol., 166: 4826-4830, 2001.
-
(2001)
J. Immunol.
, vol.166
, pp. 4826-4830
-
-
Liu, K.1
Hodes, R.J.2
Weng, N.3
-
7
-
-
0036645153
-
Cytokines modulate telomerase activity in a human multiple myeloma cell line
-
Akiyama, M., Hideshima, T., Hayashi, T., Tai, Y. T., Mitsiades, C. S., Mitsiades, N., Chauhan, D., Richardson, P., Munshi, N. C., and Anderson, K. C. Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res., 62: 3876-3882, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 3876-3882
-
-
Akiyama, M.1
Hideshima, T.2
Hayashi, T.3
Tai, Y.T.4
Mitsiades, C.S.5
Mitsiades, N.6
Chauhan, D.7
Richardson, P.8
Munshi, N.C.9
Anderson, K.C.10
-
8
-
-
0036311278
-
Nucleolar localization of hTERT protein is associated with telomerase function
-
Yang, Y., Chen, Y., Zhang, C., Huang, H., and Weissman, S. M. Nucleolar localization of hTERT protein is associated with telomerase function. Exp. Cell Res., 277: 201-209, 2002.
-
(2002)
Exp. Cell Res.
, vol.277
, pp. 201-209
-
-
Yang, Y.1
Chen, Y.2
Zhang, C.3
Huang, H.4
Weissman, S.M.5
-
9
-
-
0037025334
-
The nucleolar localization domain of the catalytic subunit of human telomerase
-
Etheridge, K. T., Banik, S. S. R., Armbruster, B. N., Zhu, Y., Terns, B. M., Terns, M. P., and Counter, C. M. The nucleolar localization domain of the catalytic subunit of human telomerase. J. Biol. Chem., 277: 24764-24770, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24764-24770
-
-
Etheridge, K.T.1
Banik, S.S.R.2
Armbruster, B.N.3
Zhu, Y.4
Terns, B.M.5
Terns, M.P.6
Counter, C.M.7
-
10
-
-
0036711651
-
Subnuclear shuttling of human telomerase induced by transformation and DNA damage
-
Wong, J. M. Y., Kusdra, L., and Collins, K. Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nat. Cell. Biol., 4: 731-736, 2002.
-
(2002)
Nat. Cell. Biol.
, vol.4
, pp. 731-736
-
-
Wong, J.M.Y.1
Kusdra, L.2
Collins, K.3
-
11
-
-
0035958517
-
The role of tumor necrosis factor α in the pathophysiology of human multiple myeloma: Therapeutic applications
-
Hideshima, T., Chauhan, D., Schlossman, R., Richardson, P., and Anderson, K. C. The role of tumor necrosis factor α in the pathophysiology of human multiple myeloma: therapeutic applications. Oncogene, 20: 4519-4527, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 4519-4527
-
-
Hideshima, T.1
Chauhan, D.2
Schlossman, R.3
Richardson, P.4
Anderson, K.C.5
-
12
-
-
85047699198
-
Nuclear transcription factor-κB as a target for cancer drug development
-
Garg, A., and Aggarwal, B. B. Nuclear transcription factor-κB as a target for cancer drug development. Leukemia (Baltimore), 16: 1053-1068, 2002.
-
(2002)
Leukemia (Baltimore)
, vol.16
, pp. 1053-1068
-
-
Garg, A.1
Aggarwal, B.B.2
-
13
-
-
0033602407
-
The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal
-
Liang, S. H., and Clarke, M. F. The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal. Oncogene, 18: 2163-2166, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 2163-2166
-
-
Liang, S.H.1
Clarke, M.F.2
-
14
-
-
17944367982
-
The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation
-
Heppner, C., Bilimoria, K. Y., Agarwal, S. K., Kester, M., Whitty, L. J., Guru, S. C., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M., Marx, S. J., and Burns, A. L. The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation. Oncogene, 20: 4917-4925, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 4917-4925
-
-
Heppner, C.1
Bilimoria, K.Y.2
Agarwal, S.K.3
Kester, M.4
Whitty, L.J.5
Guru, S.C.6
Chandrasekharappa, S.C.7
Collins, F.S.8
Spiegel, A.M.9
Marx, S.J.10
Burns, A.L.11
-
15
-
-
18544367201
-
NF-κB as a therapeutic target in multiple myeloma
-
Hideshima, T., Chauhan, D., Richardson, P., Mitsiades, C., Mitsiades, N., Hayashi, T., Munshi, N., Dong, L., Castro, A., Palombella, V., Adams, J., and Anderson, K. C. NF-κB as a therapeutic target in multiple myeloma. J. Biol. Chem., 277: 16639-16647, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
Mitsiades, C.4
Mitsiades, N.5
Hayashi, T.6
Munshi, N.7
Dong, L.8
Castro, A.9
Palombella, V.10
Adams, J.11
Anderson, K.C.12
-
16
-
-
0036624741
-
Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: Therapeutic applications
-
Mitsiades, N., Mitsiades, C. S., Poulaki, V., Chauhan, D., Richardson, P. G., Hideshima, T., Munshi, N., Treon, S. P., and Anderson, K. C. Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: therapeutic applications. Blood, 99: 4079-4086, 2002.
-
(2002)
Blood
, vol.99
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.7
Treon, S.P.8
Anderson, K.C.9
-
17
-
-
0033121314
-
Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2
-
Feinman, R., Koury, J., Thames, M., Barlogie, B., Epstein, J., and Siegel, D. S. Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2. Blood, 93: 3044-3052, 1999.
-
(1999)
Blood
, vol.93
, pp. 3044-3052
-
-
Feinman, R.1
Koury, J.2
Thames, M.3
Barlogie, B.4
Epstein, J.5
Siegel, D.S.6
-
18
-
-
0037158513
-
Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: Therapeutic implications
-
Mitsiades, C. S., Mitsiades, N., Poulaki, V., Richardson, P. G., Schlossman, R., Akiyama, M., Chauhan, D., Hideshima, T., Munshi, N., Treon, S. P., and Anderson, K. C. Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene, 21: 5673-5683, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
Richardson, P.G.4
Schlossman, R.5
Akiyama, M.6
Chauhan, D.7
Hideshima, T.8
Munshi, N.9
Treon, S.P.10
Anderson, K.C.11
-
19
-
-
0034331194
-
Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
-
Hideshima, T., Chauhan, D., Shima, Y., Raje, N., Davies, F. E., Tai, Y. T., Treon, S., Lin, B., Schlossman, R. L., Richardson, P., Muller, G., Stirling, D. I., and Anderson, K. C. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood, 96: 2943-2950, 2000.
-
(2000)
Blood
, vol.96
, pp. 2943-2950
-
-
Hideshima, T.1
Chauhan, D.2
Shima, Y.3
Raje, N.4
Davies, F.E.5
Tai, Y.T.6
Treon, S.7
Lin, B.8
Schlossman, R.L.9
Richardson, P.10
Muller, G.11
Stirling, D.I.12
Anderson, K.C.13
-
20
-
-
0035793794
-
Telomerase activity in plasma cell dyscrasias
-
Xu, D., Zheng, C., Bergenbrant, S., Holm, G., Bjorkholm, M., Yi, Q., and Gruber, A. Telomerase activity in plasma cell dyscrasias. Br. J. Cancer, 84: 621-625, 2001.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 621-625
-
-
Xu, D.1
Zheng, C.2
Bergenbrant, S.3
Holm, G.4
Bjorkholm, M.5
Yi, Q.6
Gruber, A.7
-
21
-
-
0037089647
-
Clinical significance of telomerase activity in multiple myeloma
-
Shiratsuchi, M., Muta, K., Abe, Y., Motomura, S., Taguchi, F., Takatsuki, H., Uike, N., Umemura, T., Nawata, H., and Nishimura, J. Clinical significance of telomerase activity in multiple myeloma. Cancer (Phila.), 94: 2232-2238, 2002.
-
(2002)
Cancer (Phila.)
, vol.94
, pp. 2232-2238
-
-
Shiratsuchi, M.1
Muta, K.2
Abe, Y.3
Motomura, S.4
Taguchi, F.5
Takatsuki, H.6
Uike, N.7
Umemura, T.8
Nawata, H.9
Nishimura, J.10
|