메뉴 건너뛰기




Volumn 3, Issue , 2012, Pages

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P100; PROTEIN P52; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE FBW7; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3;

EID: 84864837496     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1975     Document Type: Article
Times cited : (77)

References (47)
  • 1
    • 38549086019 scopus 로고    scopus 로고
    • FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
    • DOI 10.1038/nrc2290, PII NRC2290
    • Welcker, M. & Clurman, B. E. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat. Rev. 8, 83-93 (2008). (Pubitemid 351161321)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.2 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 2
    • 0035921849 scopus 로고    scopus 로고
    • Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
    • DOI 10.1038/35095076
    • Strohmaier, H. et al. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 413, 316-322 (2001). (Pubitemid 32905853)
    • (2001) Nature , vol.413 , Issue.6853 , pp. 316-322
    • Strohmaier, H.1    Spruck, C.H.2    Kaiser, P.3    Won, K.-A.4    Sangfelt, O.5    Reed, S.I.6
  • 4
    • 0035929669 scopus 로고    scopus 로고
    • The notch intracellular domain is ubiquitinated and negatively regulated by the mammalian sel-10 homolog
    • Oberg, C. et al. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. The Journal of biological chemistry 276, 35847-35853 (2001).
    • (2001) The Journal of biological chemistry , vol.276 , pp. 35847-35853
    • Oberg, C.1
  • 5
    • 79952261405 scopus 로고    scopus 로고
    • Scf(fbw7) regulates cellular apoptosis by targeting mcl1 for ubiquitylation and destruction
    • Inuzuka, H. et al. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. Nature 471, 104-109 (2011).
    • (2011) Nature , vol.471 , pp. 104-109
    • Inuzuka, H.1
  • 9
    • 53049097854 scopus 로고    scopus 로고
    • The fbxw7/hcdc4 tumor suppressor in human cancer
    • Tan, Y., Sangfelt, O. & Spruck, C. The Fbxw7/hCdc4 tumor suppressor in human cancer. Cancer Lett. 271, 1-12 (2008).
    • (2008) Cancer Lett. , vol.271 , pp. 1-12
    • Tan, Y.1    Sangfelt, O.2    Spruck, C.3
  • 10
    • 34047249627 scopus 로고    scopus 로고
    • Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
    • DOI 10.1016/j.molcel.2007.02.022, PII S1097276507001220
    • Hao, B., Oehlmann, S., Sowa, M. E., Harper, J. W. & Pavletich, N. P. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol. Cell 26, 131-143 (2007). (Pubitemid 46550934)
    • (2007) Molecular Cell , vol.26 , Issue.1 , pp. 131-143
    • Hao, B.1    Oehlmann, S.2    Sowa, M.E.3    Harper, J.W.4    Pavletich, N.P.5
  • 12
    • 34047255191 scopus 로고    scopus 로고
    • Fbw7/hcdc4 dimerization regulates its substrate interactions
    • Welcker, M. & Clurman, B. E. Fbw7/hCDC4 dimerization regulates its substrate interactions. Cell Div. 2, 7 (2007).
    • (2007) Cell Div. , vol.2 , pp. 7
    • Welcker, M.1    Clurman, B.E.2
  • 13
    • 0037462424 scopus 로고    scopus 로고
    • Cdc4 ubiquitin ligase
    • DOI 10.1016/S0092-8674(03)00034-5
    • Orlicky, S., Tang, X., Willems, A., Tyers, M. & Sicheri, F. Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell 112, 243-256 (2003). (Pubitemid 36144113)
    • (2003) Cell , vol.112 , Issue.2 , pp. 243-256
    • Orlicky, S.1    Tang, X.2    Willems, A.3    Tyers, M.4    Sicheri, F.5
  • 14
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • DOI 10.1146/annurev.immunol.14.1.649
    • Baldwin, A. S. Jr. The NF-kappaB and I kappaB proteins: new discoveries and insights. Annu. Rev. Immunol. 14, 649-683 (1996). (Pubitemid 26130197)
    • (1996) Annual Review of Immunology , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 15
    • 36549036709 scopus 로고    scopus 로고
    • A cell cycle regulatory network controlling NF-κB subunit activity and function
    • DOI 10.1038/sj.emboj.7601899, PII 7601899
    • Barre, B. & Perkins, N. D. A cell cycle regulatory network controlling NF-kappaB subunit activity and function. EMBO J. 26, 4841-4855 (2007). (Pubitemid 350191299)
    • (2007) EMBO Journal , vol.26 , Issue.23 , pp. 4841-4855
    • Barre, B.1    Perkins, N.D.2
  • 16
    • 78650920066 scopus 로고    scopus 로고
    • Non-canonical nf-kappab signaling pathway
    • Sun, S. C. Non-canonical NF-kappaB signaling pathway. Cell Res. 21, 71-85 (2011).
    • (2011) Cell Res. , vol.21 , pp. 71-85
    • Sun, S.C.1
  • 17
    • 78650907445 scopus 로고    scopus 로고
    • A single nf-kappab system for both canonical and non-canonical signaling
    • Shih, V. F., Tsui, R., Caldwell, A. & Hoffmann, A. A single NF-kappaB system for both canonical and non-canonical signaling. Cell Res. 21, 86-102 (2011).
    • (2011) Cell Res. , vol.21 , pp. 86-102
    • Shih, V.F.1    Tsui, R.2    Caldwell, A.3    Hoffmann, A.4
  • 19
    • 77957113912 scopus 로고    scopus 로고
    • Tumor suppressor fbxw7 regulates tgfbeta signaling by targeting tgif1 for degradation
    • Bengoechea-Alonso, M. T. & Ericsson, J. Tumor suppressor Fbxw7 regulates TGFbeta signaling by targeting TGIF1 for degradation. Oncogene 29, 5322-5328 (2010).
    • (2010) Oncogene , vol.29 , pp. 5322-5328
    • Bengoechea-Alonso, M.T.1    Ericsson, J.2
  • 20
    • 51749095471 scopus 로고    scopus 로고
    • Fbxw7 targets mtor for degradation and cooperates with pten in tumor suppression
    • Mao, J. H. et al. FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science 321, 1499-1502 (2008).
    • (2008) Science , vol.321 , pp. 1499-1502
    • Mao, J.H.1
  • 21
    • 77953310667 scopus 로고    scopus 로고
    • The fbw7/human cdc4 tumor suppressor targets proproliferative factor klf5 for ubiquitination and degradation through multiple phosphodegron motifs
    • Liu, N. et al. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J. Biol. Chem. 285, 18858-18867 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 18858-18867
    • Liu, N.1
  • 22
    • 2942564430 scopus 로고    scopus 로고
    • Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence
    • DOI 10.1002/pmic.200300771
    • Blom, N., Sicheritz-Ponten, T., Gupta, R., Gammeltoft, S. & Brunak, S. Prediction of post-Translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4, 1633-1649 (2004). (Pubitemid 38738322)
    • (2004) Proteomics , vol.4 , Issue.6 , pp. 1633-1649
    • Blom, N.1    Sicheritz-Ponten, T.2    Gupta, R.3    Gammeltoft, S.4    Brunak, So.5
  • 23
    • 0034745420 scopus 로고    scopus 로고
    • NF-κB-inducing kinase regulates the processing of NF-κB2 p100
    • DOI 10.1016/S1097-2765(01)00187-3
    • Xiao, G., Harhaj, E. W. & Sun, S. C. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol. Cell 7, 401-409 (2001). (Pubitemid 32206507)
    • (2001) Molecular Cell , vol.7 , Issue.2 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.-C.3
  • 24
    • 0037931474 scopus 로고    scopus 로고
    • RelB/p50 dimers are differentially regulated by tumor necrosis factor-α and lymphotoxin-β receptor activation. Critical roles for p100
    • DOI 10.1074/jbc.M300106200
    • Derudder, E. et al. RelB/p50 dimers are differentially regulated by tumor necrosis factor-Alpha and lymphotoxin-beta receptor activation: critical roles for p100. J. Biol. Chem. 278, 23278-23284 (2003). (Pubitemid 36830141)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.26 , pp. 23278-23284
    • Derudder, E.1    Dejardin, E.2    Pritchard, L.L.3    Green, D.R.4    Korner, M.5    Baud, V.6
  • 25
    • 0035803392 scopus 로고    scopus 로고
    • Retroviral oncoprotein tax induces processing of NF-κB2/p100 in T cells: Evidence for the involvement of IKKα
    • DOI 10.1093/emboj/20.23.6805
    • Xiao, G. et al. Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha. EMBO J. 20, 6805-6815 (2001). (Pubitemid 33134210)
    • (2001) EMBO Journal , vol.20 , Issue.23 , pp. 6805-6815
    • Xiao, G.1    Cvijic, M.E.2    Fong, A.3    Harhaj, E.W.4    Uhlik, M.T.5    Waterfield, M.6    Sun, S.-C.7
  • 28
    • 84859430011 scopus 로고    scopus 로고
    • Fbxw7alpha-And gsk3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma
    • Busino, L. et al. Fbxw7alpha-And GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nat. Cell Biol. 14, 375-385 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , pp. 375-385
    • Busino, L.1
  • 30
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of nf-kappab subunits in cancer
    • Perkins, N. D. The diverse and complex roles of NF-kappaB subunits in cancer. Nat. Rev. Cancer 12, 121-132 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 32
    • 33646336615 scopus 로고    scopus 로고
    • Beta-TrCP binding and processing of NF-κB2/p100 involve its phosphorylation at serines 866 and 870
    • DOI 10.1016/j.cellsig.2005.10.011, PII S0898656805002883
    • Liang, C., Zhang, M. & Sun, S. C. beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. Cell Signal 18, 1309-1317 (2006). (Pubitemid 43674034)
    • (2006) Cellular Signalling , vol.18 , Issue.8 , pp. 1309-1317
    • Liang, C.1    Zhang, M.2    Sun, S.-C.3
  • 35
    • 33745852665 scopus 로고    scopus 로고
    • Alternative pathways of NF-κB activation: A double-edged sword in health and disease
    • DOI 10.1016/j.cytogfr.2006.04.005, PII S1359610106000293
    • Xiao, G., Rabson, A. B., Young, W., Qing, G. & Qu, Z. Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease. Cytokine Growth Factor Rev. 17, 281-293 (2006). (Pubitemid 44038617)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.4 , pp. 281-293
    • Xiao, G.1    Rabson, A.B.2    Young, W.3    Qing, G.4    Qu, Z.5
  • 36
    • 79959658547 scopus 로고    scopus 로고
    • Nf-kappa b and cancer: A paradigm of yin-yang
    • Xiao, G. & Fu, J. NF-kappaB and cancer: a paradigm of Yin-Yang. Am. J. Cancer Res. 1, 192-221 (2011).
    • (2011) Am. J. Cancer Res. , vol.1 , pp. 192-221
    • Xiao, G.1    Fu, J.2
  • 38
    • 33745508920 scopus 로고    scopus 로고
    • Ubiquitylation of cyclin e requires the sequential function of scf complexes containing distinct hcdc4 isoforms
    • van Drogen, F. et al. Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms. Mol. Cell 23, 37-48 (2006).
    • (2006) Mol. Cell , vol.23 , pp. 37-48
    • Van Drogen, F.1
  • 39
    • 0038409927 scopus 로고    scopus 로고
    • P53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-κB subunit with histone deacetylase 1
    • DOI 10.1128/MCB.23.13.4713-4727.2003
    • Rocha, S., Martin, A. M., Meek, D. W. & Perkins, N. D. p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1. Mol. Cell. Biol. 23, 4713-4727 (2003). (Pubitemid 36740458)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.13 , pp. 4713-4727
    • Rocha, S.1    Martin, A.M.2    Meek, D.W.3    Perkins, N.D.4
  • 40
    • 79959923295 scopus 로고    scopus 로고
    • Mirna-27a controls fbw7/hcdc4-dependent cyclin e degradation and cell cycle progression
    • Lerner, M. et al. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression. Cell cycle 10, 2172-2183 (2011).
    • (2011) Cell cycle , vol.10 , pp. 2172-2183
    • Lerner, M.1
  • 41
    • 79851471726 scopus 로고    scopus 로고
    • Evolutionary conserved regulation of hif-1ß by nf-kappab
    • van Uden, P. et al. Evolutionary conserved regulation of HIF-1ß by NF-kappaB. PLoS Genet. 7, e1001285 (2011).
    • (2011) PLoS Genet. , vol.7
    • Van Uden, P.1
  • 42
    • 58749097408 scopus 로고    scopus 로고
    • A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: A genome-wide classification study
    • Den Boer, M. L. et al. A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol. 10, 125-134 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 125-134
    • Den Boer, M.L.1
  • 43
    • 49749131566 scopus 로고    scopus 로고
    • Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms
    • Eriksson, H. et al. Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms. Proteomics 8, 3008-3018 (2008).
    • (2008) Proteomics , vol.8 , pp. 3008-3018
    • Eriksson, H.1
  • 44
    • 35748972060 scopus 로고    scopus 로고
    • Semi-supervised learning for peptide identification from shotgun proteomics datasets
    • DOI 10.1038/nmeth1113, PII NMETH1113
    • Kall, L., Canterbury, J. D., Weston, J., Noble, W. S. & MacCoss, M. J. Semi-supervised learning for peptide identification from shotgun proteomics datasets. Nat. Methods 4, 923-925 (2007). (Pubitemid 350042380)
    • (2007) Nature Methods , vol.4 , Issue.11 , pp. 923-925
    • Kall, L.1    Canterbury, J.D.2    Weston, J.3    Noble, W.S.4    MacCoss, M.J.5
  • 45
    • 78651319979 scopus 로고    scopus 로고
    • Ongoing and future developments at the universal protein resource
    • Ongoing and future developments at the Universal Protein Resource. Nucleic Acids Res. 39, D214-D219 (2011).
    • (2011) Nucleic Acids Res. , vol.39
  • 46
    • 80054013297 scopus 로고    scopus 로고
    • Enhanced information output from shotgun proteomics data by protein quantification and peptide quality control (pqpq)
    • Forshed, J. et al. Enhanced information output from shotgun proteomics data by protein quantification and peptide quality control (PQPQ). Mol. Cell Proteomics 10, M111 010264 (2011).
    • (2011) Mol. Cell Proteomics , vol.10
    • Forshed, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.